Breast Cancer Histology Image Classification

The evaluation of human epidermal growth factor receptor 2 (HER2) expression is essential to formulate a precise treatment for breast cancer. The routine evaluation of HER2 is conducted with immunohistochemical techniques (IHC), which is very expensive. Therefore, we propose a breast cancer immunohistochemical (BCI) benchmark attempting to synthesize IHC data directly with the paired hematoxylin and eosin (HE) stained images. The dataset contains 4870 registered image pairs, covering a variety of HER2 expression levels (0, 1+, 2+, 3+).

The Breast Cancer Histopathological Image Classification (BreakHis) is composed of 9,109 microscopic images of breast tumor tissue collected from 82 patients using different magnifying factors (40X, 100X, 200X, and 400X). It contains 2,480 benign and 5,429 malignant samples (700X460 pixels, 3-channel RGB, 8-bit depth in each channel, PNG format). This database has been built in collaboration with the P&D Laboratory - Pathological Anatomy and Cytopathology, Parana, Brazil. Paper: F. A. Spanhol, L. S. Oliveira, C. Petitjean and L. Heutte, "A Dataset for Breast Cancer Histopathological Image Classification," in IEEE Transactions on Biomedical Engineering, vol. 63, no. 7, pp. 1455-1462, July 2016, doi: 10.1109/TBME.2015.2496264 Source: https://web.inf.ufpr.br/vri/databases/breast-cancer-histopathological-database-breakhis/ Image Source: https://web.inf.ufpr.br/vri/databases/breast-cancer-histopathological-database-breakhis/

The dataset is composed of Hematoxylin and eosin (H&E) stained breast histology microscopy and whole-slide images. Challenge participants should evaluate the performance of their method on either/both sets of images.