Photoacoustic microscopy holds the potential to measure biomarkers' structural and functional status without labels, which significantly aids in comprehending pathophysiological conditions in biomedical research. However, conventional optical-resolution photoacoustic microscopy (OR-PAM) is hindered by a limited depth-of-field (DoF) due to the narrow depth range focused on a Gaussian beam. Consequently, it fails to resolve sufficient details in the depth direction. Herein, we propose a decision-level constrained end-to-end multi-focus image fusion (Dc-EEMF) to push DoF limit of PAM. The DC-EEMF method is a lightweight siamese network that incorporates an artifact-resistant channel-wise spatial frequency as its feature fusion rule. The meticulously crafted U-Net-based perceptual loss function for decision-level focus properties in end-to-end fusion seamlessly integrates the complementary advantages of spatial domain and transform domain methods within Dc-EEMF. This approach can be trained end-to-end without necessitating post-processing procedures. Experimental results and numerical analyses collectively demonstrate our method's robust performance, achieving an impressive fusion result for PAM images without a substantial sacrifice in lateral resolution. The utilization of Dc-EEMF-powered PAM has the potential to serve as a practical tool in preclinical and clinical studies requiring extended DoF for various applications.
Image fusion integrates essential information from multiple images into a single composite, enhancing structures, textures, and refining imperfections. Existing methods predominantly focus on pixel-level and semantic visual features for recognition, but often overlook the deeper text-level semantic information beyond vision. Therefore, we introduce a novel fusion paradigm named image Fusion via vIsion-Language Model (FILM), for the first time, utilizing explicit textual information from source images to guide the fusion process. Specifically, FILM generates semantic prompts from images and inputs them into ChatGPT for comprehensive textual descriptions. These descriptions are fused within the textual domain and guide the visual information fusion, enhancing feature extraction and contextual understanding, directed by textual semantic information via cross-attention. FILM has shown promising results in four image fusion tasks: infrared-visible, medical, multi-exposure, and multi-focus image fusion. We also propose a vision-language dataset containing ChatGPT-generated paragraph descriptions for the eight image fusion datasets across four fusion tasks, facilitating future research in vision-language model-based image fusion. Code and dataset are available at https://github.com/Zhaozixiang1228/IF-FILM.
Existing multi-focus image fusion (MFIF) methods often fail to preserve the uncertain transition region and detect small focus areas within large defocused regions accurately. To address this issue, this study proposes a new small-area-aware MFIF algorithm for enhancing object detection capability. First, we enhance the pixel attributes within the small focus and boundary regions, which are subsequently combined with visual saliency detection to obtain the pre-fusion results used to discriminate the distribution of focused pixels. To accurately ensure pixel focus, we consider the source image as a combination of focused, defocused, and uncertain regions and propose a three-region segmentation strategy. Finally, we design an effective pixel selection rule to generate segmentation decision maps and obtain the final fusion results. Experiments demonstrated that the proposed method can accurately detect small and smooth focus areas while improving object detection performance, outperforming existing methods in both subjective and objective evaluations. The source code is available at https://github.com/ixilai/SAMF.
Cameras are limited in their ability to capture all-in-focus images due to their limited depth of field. This results in blurriness for objects too far in front of or behind the focused point. To overcome this limitation, multi-focus image fusion (MFIF) approaches have been proposed. Although recent MFIF methods have shown promising results for this task, they still need to be improved in terms of artifacts and color degradation. Motivated by these observations, in this paper, we propose a new Generative Adversarial Network (GAN)–based MFIF model to improve fusion quality by predicting more accurate focus maps thanks to a trainable guided filter we incorporated. The proposed model comprises an encoder-decoder network, and a trainable self-guided filtering (TSGF) module that is specifically designed to enhance spatial consistency in the predicted focus map and to eliminate the requirements of post-processing in existing GAN-based methods. The encoder-decoder network first predicts raw focus maps, which are then passed to the TSGF to produce the final focus maps. To train the proposed model effectively, we define three objectives: L1 loss, GAN loss, and Focal Frequency Loss (FFL) in the frequency domain. L1 loss is defined on ground-truth and predicted focus maps, whereas GAN loss and FFL are defined on ground-truth all-in-focus images and fused images. Experimental results show that the proposed approach outperforms the existing GAN-based methods and achieves highly competitive performance with state-of-the-art methods in terms of standard quantitative image fusion metrics and visual quality on three MFIF benchmark datasets.
Focus stacking is widely used in micro, macro, and landscape photography to reconstruct all-in-focus images from multiple frames obtained with focus bracketing, that is, with shallow depth of field and different focus planes. Existing deep learning approaches to the underlying multi-focus image fusion problem have limited applicability to real-world imagery since they are designed for very short image sequences (two to four images), and are typically trained on small, low-resolution datasets either acquired by light-field cameras or generated synthetically. We introduce a new dataset consisting of 94 high-resolution bursts of raw images with focus bracketing, with pseudo ground truth computed from the data using state-of-the-art commercial software. This dataset is used to train the first deep learning algorithm for focus stacking capable of handling bursts of sufficient length for real-world applications. Qualitative experiments demonstrate that it is on par with existing commercial solutions in the long-burst, realistic regime while being significantly more tolerant to noise. The code and dataset are available at https://github.com/araujoalexandre/FocusStackingDataset.
Multi-focus is a technique of focusing on different aspects of a particular object or scene. Wireless Visual Sensor Networks (WVSN) use multi-focus image fusion, which combines two or more images to create a more accurate output image that describes the scene better than any individual input image. WVSN has various applications, including video surveillance, monitoring, and tracking. Therefore, a high-level analysis of these networks can benefit Biometrics. This paper introduces an algorithm that utilizes discrete cosine transform (DCT) standards to fuse multi-focus images in WVSNs. The spatial frequency (SF) of the corresponding blocks from the source images determines the fusion criterion. The blocks with higher spatial frequencies make up the DCT presentation of the fused image, and the Consistency Verification (CV) procedure is used to enhance the output image quality. The proposed fusion method was tested on multiple pairs of multi-focus images coded on JPEG standard to evaluate the fusion performance, and the results indicate that it improves the visual quality of the output image and outperforms other DCT-based techniques.
Multi-focus image fusion is a challenging field of study that aims to provide a completely focused image by integrating focused and un-focused pixels. Most existing methods suffer from shift variance, misregistered images, and data-dependent. In this study, we introduce a novel gradient information-based multi-focus image fusion method that is robust for the aforementioned problems. The proposed method first generates gradient images from original images by using Halftoning-Inverse Halftoning (H-IH) transform. Then, Energy of Gradient (EOG) and Standard Deviation functions are used as the focus measurement on the gradient images to form a fused image. Finally, in order to enhance the fused image a decision fusion approach is applied with the majority voting method. The proposed method is compared with 17 different novel and conventional techniques both visually and objectively. For objective evaluation, 6 different quantitative metrics are used. It is observed that the proposed method is promising according to visual evaluation and 83.3% success is achieved by being first in five out of six metrics according to objective evaluation.
Image fusion is a technique to integrate information from multiple source images with complementary information to improve the richness of a single image. Due to insufficient task-specific training data and corresponding ground truth, most existing end-to-end image fusion methods easily fall into overfitting or tedious parameter optimization processes. Two-stage methods avoid the need of large amount of task-specific training data by training encoder-decoder network on large natural image datasets and utilizing the extracted features for fusion, but the domain gap between natural images and different fusion tasks results in limited performance. In this study, we design a novel encoder-decoder based image fusion framework and propose a destruction-reconstruction based self-supervised training scheme to encourage the network to learn task-specific features. Specifically, we propose three destruction-reconstruction self-supervised auxiliary tasks for multi-modal image fusion, multi-exposure image fusion and multi-focus image fusion based on pixel intensity non-linear transformation, brightness transformation and noise transformation, respectively. In order to encourage different fusion tasks to promote each other and increase the generalizability of the trained network, we integrate the three self-supervised auxiliary tasks by randomly choosing one of them to destroy a natural image in model training. In addition, we design a new encoder that combines CNN and Transformer for feature extraction, so that the trained model can exploit both local and global information. Extensive experiments on multi-modal image fusion, multi-exposure image fusion and multi-focus image fusion tasks demonstrate that our proposed method achieves the state-of-the-art performance in both subjective and objective evaluations. The code will be publicly available soon.
Multi-focus image fusion (MFIF) and super-resolution (SR) are the inverse problem of imaging model, purposes of MFIF and SR are obtaining all-in-focus and high-resolution 2D mapping of targets. Though various MFIF and SR methods have been designed; almost all the them deal with MFIF and SR separately. This paper unifies MFIF and SR problems in the physical perspective as the multi-focus image super resolution fusion (MFISRF), and we propose a novel unified dataset-free unsupervised framework named deep fusion prior (DFP) based-on deep image prior (DIP) to address such MFISRF with single model. Experiments have proved that our proposed DFP approaches or even outperforms those state-of-art MFIF and SR method combinations. To our best knowledge, our proposed work is a dataset-free unsupervised method to simultaneously implement the multi-focus fusion and super-resolution task for the first time. Additionally, DFP is a general framework, thus its networks and focus measurement tactics can be continuously updated to further improve the MFISRF performance. DFP codes are open source available at http://github.com/GuYuanjie/DeepFusionPrior.
In recent years, various applications in computer vision have achieved substantial progress based on deep learning, which has been widely used for image fusion and shown to achieve adequate performance. However, suffering from limited ability in modeling the spatial correspondence of different source images, it still remains a great challenge for existing unsupervised image fusion models to extract appropriate feature and achieves adaptive and balanced fusion. In this paper, we propose a novel cross-attention-guided image fusion network, which is a unified and unsupervised framework for multi-modal image fusion, multi-exposure image fusion, and multi-focus image fusion. Different from the existing self-attention module, our cross-attention module focus on modeling the cross-correlation between different source images. Using the proposed cross attention module as a core block, a densely connected cross attention-guided network is built to dynamically learn the spatial correspondence to derive better alignment of important details from different input images. Meanwhile, an auxiliary branch is also designed to model the long-range information, and a merging network is attached to finally reconstruct the fusion image. Extensive experiments have been carried out on publicly available datasets, and the results demonstrate that the proposed model outperforms the state-of-the-art quantitatively and qualitatively.
Depth information is useful in many image processing applications. However, since taking a picture is a process of projection of a 3D scene onto a 2D imaging sensor, the depth information is embedded in the image. Extracting the depth information from the image is a challenging task. A guiding principle is that the level of blurriness due to defocus is related to the distance between the object and the focal plane. Based on this principle and the widely used assumption that Gaussian blur is a good model for defocus blur, we formulate the problem of estimating the spatially varying defocus blurriness as a Gaussian blur classification problem. We solved the problem by training a deep neural network to classify image patches into one of the 20 levels of blurriness. We have created a dataset of more than 500000 image patches of size $32\times32$ which are used to train and test several well-known network models. We find that MobileNetV2 is suitable for this application due to its low memory requirement and high accuracy. The trained model is used to determine the patch blurriness which is then refined by applying an iterative weighted guided filter. The result is a defocus map that carries the information of the degree of blurriness for each pixel. We compare the proposed method with state-of-the-art techniques and we demonstrate its successful applications in adaptive image enhancement, defocus magnification, and multi-focus image fusion.
Traditional and deep learning-based fusion methods generated the intermediate decision map to obtain the fusion image through a series of post-processing procedures. However, the fusion results generated by these methods are easy to lose some source image details or results in artifacts. Inspired by the image reconstruction techniques based on deep learning, we propose a multi-focus image fusion network framework without any post-processing to solve these problems in the end-to-end and supervised learning way. To sufficiently train the fusion model, we have generated a large-scale multi-focus image dataset with ground-truth fusion images. What's more, to obtain a more informative fusion image, we further designed a novel fusion strategy based on unity fusion attention, which is composed of a channel attention module and a spatial attention module. Specifically, the proposed fusion approach mainly comprises three key components: feature extraction, feature fusion and image reconstruction. We firstly utilize seven convolutional blocks to extract the image features from source images. Then, the extracted convolutional features are fused by the proposed fusion strategy in the feature fusion layer. Finally, the fused image features are reconstructed by four convolutional blocks. Experimental results demonstrate that the proposed approach for multi-focus image fusion achieves remarkable fusion performance compared to 19 state-of-the-art fusion methods.
Multi-focus image fusion (MFF) is a popular technique to generate an all-in-focus image, where all objects in the scene are sharp. However, existing methods pay little attention to defocus spread effects of the real-world multi-focus images. Consequently, most of the methods perform badly in the areas near focus map boundaries. According to the idea that each local region in the fused image should be similar to the sharpest one among source images, this paper presents an optimization-based approach to reduce defocus spread effects. Firstly, a new MFF assessmentmetric is presented by combining the principle of structure similarity and detected focus maps. Then, MFF problem is cast into maximizing this metric. The optimization is solved by gradient ascent. Experiments conducted on the real-world dataset verify superiority of the proposed model. The codes are available at https://github.com/xsxjtu/MFF-SSIM.
The general aim of multi-focus image fusion is to gather focused regions of different images to generate a unique all-in-focus fused image. Deep learning based methods become the mainstream of image fusion by virtue of its powerful feature representation ability. However, most of the existing deep learning structures failed to balance fusion quality and end-to-end implementation convenience. End-to-end decoder design often leads to unrealistic result because of its non-linear mapping mechanism. On the other hand, generating an intermediate decision map achieves better quality for the fused image, but relies on the rectification with empirical post-processing parameter choices. In this work, to handle the requirements of both output image quality and comprehensive simplicity of structure implementation, we propose a cascade network to simultaneously generate decision map and fused result with an end-to-end training procedure. It avoids the dependence on empirical post-processing methods in the inference stage. To improve the fusion quality, we introduce a gradient aware loss function to preserve gradient information in output fused image. In addition, we design a decision calibration strategy to decrease the time consumption in the application of multiple images fusion. Extensive experiments are conducted to compare with 19 different state-of-the-art multi-focus image fusion structures with 6 assessment metrics. The results prove that our designed structure can generally ameliorate the output fused image quality, while implementation efficiency increases over 30\% for multiple images fusion.
Image fusion in visual sensor networks (VSNs) aims to combine information from multiple images of the same scene in order to transform a single image with more information. Image fusion methods based on discrete cosine transform (DCT) are less complex and time-saving in DCT based standards of image and video which makes them more suitable for VSN applications. In this paper, an efficient algorithm for the fusion of multi-focus images in the DCT domain is proposed. The Sum of modified laplacian (SML) of corresponding blocks of source images is used as a contrast criterion and blocks with the larger value of SML are absorbed to output images. The experimental results on several images show the improvement of the proposed algorithm in terms of both subjective and objective quality of fused image relative to other DCT based techniques.
Multi-Focus Image Fusion (MFIF) is a promising image enhancement technique to obtain all-in-focus images meeting visual needs and it is a precondition of other computer vision tasks. One of the research trends of MFIF is to avoid the defocus spread effect (DSE) around the focus/defocus boundary (FDB). In this paper,we propose a network termed MFIF-GAN to attenuate the DSE by generating focus maps in which the foreground region are correctly larger than the corresponding objects. The Squeeze and Excitation Residual module is employed in the network. By combining the prior knowledge of training condition, this network is trained on a synthetic dataset based on an {\alpha}-matte model. In addition, the reconstruction and gradient regularization terms are combined in the loss functions to enhance the boundary details and improve the quality of fused images. Extensive experiments demonstrate that the MFIF-GAN outperforms several state-of-the-art (SOTA) methods in visual perception, quantitative analysis as well as efficiency. Moreover, the edge diffusion and contraction module is firstly proposed to verify that focus maps generated by our method are accurate at the pixel level.
Multi-focus image fusion (MFIF) has attracted considerable interests due to its numerous applications. While much progress has been made in recent years with efforts on developing various MFIF algorithms, some issues significantly hinder the fair and comprehensive performance comparison of MFIF methods, such as the lack of large-scale test set and the random choices of objective evaluation metrics in the literature. To solve these issues, this paper presents a multi-focus image fusion benchmark (MFIFB) which consists a test set of 105 image pairs, a code library of 30 MFIF algorithms, and 20 evaluation metrics. MFIFB is the first benchmark in the field of MFIF and provides the community a platform to compare MFIF algorithms fairly and comprehensively. Extensive experiments have been conducted using the proposed MFIFB to understand the performance of these algorithms. By analyzing the experimental results, effective MFIF algorithms are identified. More importantly, some observations on the status of the MFIF field are given, which can help to understand this field better.
Multi-focus image fusion, a technique to generate an all-in-focus image from two or more partially-focused source images, can benefit many computer vision tasks. However, currently there is no large and realistic dataset to perform convincing evaluation and comparison of algorithms in multi-focus image fusion. Moreover, it is difficult to train a deep neural network for multi-focus image fusion without a suitable dataset. In this letter, we introduce a large and realistic multi-focus dataset called Real-MFF, which contains 710 pairs of source images with corresponding ground truth images. The dataset is generated by light field images, and both the source images and the ground truth images are realistic. To serve as both a well-established benchmark for existing multi-focus image fusion algorithms and an appropriate training dataset for future development of deep-learning-based methods, the dataset contains a variety of scenes, including buildings, plants, humans, shopping malls, squares and so on. We also evaluate 10 typical multi-focus algorithms on this dataset for the purpose of illustration.
Multi-focus image fusion (MFF) is a fundamental task in the field of computational photography. Current methods have achieved significant performance improvement. It is found that current methods are evaluated on simulated image sets or Lytro dataset. Recently, a growing number of researchers pay attention to defocus spread effect, a phenomenon of real-world multi-focus images. Nonetheless, defocus spread effect is not obvious in simulated or Lytro datasets, where popular methods perform very similar. To compare their performance on images with defocus spread effect, this paper constructs a new dataset called MFF in the wild (MFFW). It contains 19 pairs of multi-focus images collected on the Internet. We register all pairs of source images, and provide focus maps and reference images for part of pairs. Compared with Lytro dataset, images in MFFW significantly suffer from defocus spread effect. In addition, the scenes of MFFW are more complex. The experiments demonstrate that most state-of-the-art methods on MFFW dataset cannot robustly generate satisfactory fusion images. MFFW can be a new baseline dataset to test whether an MMF algorithm is able to deal with defocus spread effect.
This paper presents an improved dual channel pulse coupled neural network (IDC-PCNN) model for image fusion. The model can overcome some defects of standard PCNN model. In this fusion scheme, the multiplication rule is replaced by addition rule in the information fusion pool of dual channel PCNN (DC-PCNN) model. Meanwhile the sum of modified Laplacian (SML) measure is adopted, which is better than other focus measures. This method not only inherits the good characteristics of the standard PCNN model but also enhances the computing efficiency and fusion quality. The performance of the proposed method is evaluated by using four criteria including average cross entropy, root mean square error, peak value signal to noise ratio and structure similarity index. Comparative studies show that the proposed fusion algorithm outperforms the standard PCNN method and the DC-PCNN method.