Vehicular metaverses are an emerging paradigm that merges intelligent transportation systems with virtual spaces, leveraging advanced digital twin and Artificial Intelligence (AI) technologies to seamlessly integrate vehicles, users, and digital environments. In this paradigm, vehicular AI agents are endowed with environment perception, decision-making, and action execution capabilities, enabling real-time processing and analysis of multi-modal data to provide users with customized interactive services. Since vehicular AI agents require substantial resources for real-time decision-making, given vehicle mobility and network dynamics conditions, the AI agents are deployed in RoadSide Units (RSUs) with sufficient resources and dynamically migrated among them. However, AI agent migration requires frequent data exchanges, which may expose vehicular metaverses to potential cyber attacks. To this end, we propose a reliable vehicular AI agent migration framework, achieving reliable dynamic migration and efficient resource scheduling through cooperation between vehicles and RSUs. Additionally, we design a trust evaluation model based on the theory of planned behavior to dynamically quantify the reputation of RSUs, thereby better accommodating the personalized trust preferences of users. We then model the vehicular AI agent migration process as a partially observable markov decision process and develop a Confidence-regulated Generative Diffusion Model (CGDM) to efficiently generate AI agent migration decisions. Numerical results demonstrate that the CGDM algorithm significantly outperforms baseline methods in reducing system latency and enhancing robustness against cyber attacks.
We introduce TimeSeriesGym, a scalable benchmarking framework for evaluating Artificial Intelligence (AI) agents on time series machine learning engineering challenges. Existing benchmarks lack scalability, focus narrowly on model building in well-defined settings, and evaluate only a limited set of research artifacts (e.g., CSV submission files). To make AI agent benchmarking more relevant to the practice of machine learning engineering, our framework scales along two critical dimensions. First, recognizing that effective ML engineering requires a range of diverse skills, TimeSeriesGym incorporates challenges from diverse sources spanning multiple domains and tasks. We design challenges to evaluate both isolated capabilities (including data handling, understanding research repositories, and code translation) and their combinations, and rather than addressing each challenge independently, we develop tools that support designing multiple challenges at scale. Second, we implement evaluation mechanisms for multiple research artifacts, including submission files, code, and models, using both precise numeric measures and more flexible LLM-based evaluation approaches. This dual strategy balances objective assessment with contextual judgment. Although our initial focus is on time series applications, our framework can be readily extended to other data modalities, broadly enhancing the comprehensiveness and practical utility of agentic AI evaluation. We open-source our benchmarking framework to facilitate future research on the ML engineering capabilities of AI agents.
An AI agent might surprisingly find she has reached an unknown state which she has never been aware of -- an unknown unknown. We mathematically ground this scenario in reinforcement learning: an agent, after taking an action calculated from value functions $Q$ and $V$ defined on the {\it {aware domain}}, reaches a state out of the domain. To enable the agent to handle this scenario, we propose an {\it episodic Markov decision {process} with growing awareness} (EMDP-GA) model, taking a new {\it noninformative value expansion} (NIVE) approach to expand value functions to newly aware areas: when an agent arrives at an unknown unknown, value functions $Q$ and $V$ whereon are initialised by noninformative beliefs -- the averaged values on the aware domain. This design is out of respect for the complete absence of knowledge in the newly discovered state. The upper confidence bound momentum Q-learning is then adapted to the growing awareness for training the EMDP-GA model. We prove that (1) the regret of our approach is asymptotically consistent with the state of the art (SOTA) without exposure to unknown unknowns in an extremely uncertain environment, and (2) our computational complexity and space complexity are comparable with the SOTA -- these collectively suggest that though an unknown unknown is surprising, it will be asymptotically properly discovered with decent speed and an affordable cost.
The variety of data in data lakes presents significant challenges for data analytics, as data scientists must simultaneously analyze multi-modal data, including structured, semi-structured, and unstructured data. While Large Language Models (LLMs) have demonstrated promising capabilities, they still remain inadequate for multi-modal data analytics in terms of accuracy, efficiency, and freshness. First, current natural language (NL) or SQL-like query languages may struggle to precisely and comprehensively capture users' analytical intent. Second, relying on a single unified LLM to process diverse data modalities often leads to substantial inference overhead. Third, data stored in data lakes may be incomplete or outdated, making it essential to integrate external open-domain knowledge to generate timely and relevant analytics results. In this paper, we envision a new multi-modal data analytics system. Specifically, we propose a novel architecture built upon the Model Context Protocol (MCP), an emerging paradigm that enables LLMs to collaborate with knowledgeable agents. First, we define a semantic operator hierarchy tailored for querying multi-modal data in data lakes and develop an AI-agent-powered NL2Operator translator to bridge user intent and analytical execution. Next, we introduce an MCP-based execution framework, in which each MCP server hosts specialized foundation models optimized for specific data modalities. This design enhances both accuracy and efficiency, while supporting high scalability through modular deployment. Finally, we propose a updating mechanism by harnessing the deep research and machine unlearning techniques to refresh the data lakes and LLM knowledges, with the goal of balancing the data freshness and inference efficiency.
The proliferation of AI agents requires robust mechanisms for secure discovery. This paper introduces the Agent Name Service (ANS), a novel architecture based on DNS addressing the lack of a public agent discovery framework. ANS provides a protocol-agnostic registry infrastructure that leverages Public Key Infrastructure (PKI) certificates for verifiable agent identity and trust. The architecture features several key innovations: a formalized agent registration and renewal mechanism for lifecycle management; DNS-inspired naming conventions with capability-aware resolution; a modular Protocol Adapter Layer supporting diverse communication standards (A2A, MCP, ACP etc.); and precisely defined algorithms for secure resolution. We implement structured communication using JSON Schema and conduct a comprehensive threat analysis of our proposal. The result is a foundational directory service addressing the core challenges of secured discovery and interaction in multi-agent systems, paving the way for future interoperable, trustworthy, and scalable agent ecosystems.
This study critically distinguishes between AI Agents and Agentic AI, offering a structured conceptual taxonomy, application mapping, and challenge analysis to clarify their divergent design philosophies and capabilities. We begin by outlining the search strategy and foundational definitions, characterizing AI Agents as modular systems driven by Large Language Models (LLMs) and Large Image Models (LIMs) for narrow, task-specific automation. Generative AI is positioned as a precursor, with AI Agents advancing through tool integration, prompt engineering, and reasoning enhancements. In contrast, Agentic AI systems represent a paradigmatic shift marked by multi-agent collaboration, dynamic task decomposition, persistent memory, and orchestrated autonomy. Through a sequential evaluation of architectural evolution, operational mechanisms, interaction styles, and autonomy levels, we present a comparative analysis across both paradigms. Application domains such as customer support, scheduling, and data summarization are contrasted with Agentic AI deployments in research automation, robotic coordination, and medical decision support. We further examine unique challenges in each paradigm including hallucination, brittleness, emergent behavior, and coordination failure and propose targeted solutions such as ReAct loops, RAG, orchestration layers, and causal modeling. This work aims to provide a definitive roadmap for developing robust, scalable, and explainable AI agent and Agentic AI-driven systems. >AI Agents, Agent-driven, Vision-Language-Models, Agentic AI Decision Support System, Agentic-AI Applications
With the advancement of large language models and embodied Artificial Intelligence (AI) in the intelligent transportation scenarios, the combination of them in intelligent transportation spawns the Vehicular Embodied AI Network (VEANs). In VEANs, Autonomous Vehicles (AVs) are typical agents whose local advanced AI applications are defined as vehicular embodied AI agents, enabling capabilities such as environment perception and multi-agent collaboration. Due to computation latency and resource constraints, the local AI applications and services running on vehicular embodied AI agents need to be migrated, and subsequently referred to as vehicular embodied AI agent twins, which drive the advancement of vehicular embodied AI networks to offload intensive tasks to Roadside Units (RSUs), mitigating latency problems while maintaining service quality. Recognizing workload imbalance among RSUs in traditional approaches, we model AV-RSU interactions as a Stackelberg game to optimize bandwidth resource allocation for efficient migration. A Tiny Multi-Agent Bidirectional LSTM Proximal Policy Optimization (TMABLPPO) algorithm is designed to approximate the Stackelberg equilibrium through decentralized coordination. Furthermore, a personalized neural network pruning algorithm based on Path eXclusion (PX) dynamically adapts to heterogeneous AV computation capabilities by identifying task-critical parameters in trained models, reducing model complexity with less performance degradation. Experimental validation confirms the algorithm's effectiveness in balancing system load and minimizing delays, demonstrating significant improvements in vehicular embodied AI agent deployment.
Crucial in disease analysis and surgical planning, manual segmentation of volumetric medical scans (e.g. MRI, CT) is laborious, error-prone, and challenging to master, while fully automatic algorithms can benefit from user feedback. Therefore, with the complementary power of the latest radiological AI foundation models and virtual reality (VR)'s intuitive data interaction, we propose SAMIRA, a novel conversational AI agent for medical VR that assists users with localizing, segmenting, and visualizing 3D medical concepts. Through speech-based interaction, the agent helps users understand radiological features, locate clinical targets, and generate segmentation masks that can be refined with just a few point prompts. The system also supports true-to-scale 3D visualization of segmented pathology to enhance patient-specific anatomical understanding. Furthermore, to determine the optimal interaction paradigm under near-far attention-switching for refining segmentation masks in an immersive, human-in-the-loop workflow, we compare VR controller pointing, head pointing, and eye tracking as input modes. With a user study, evaluations demonstrated a high usability score (SUS=90.0 $\pm$ 9.0), low overall task load, as well as strong support for the proposed VR system's guidance, training potential, and integration of AI in radiological segmentation tasks.
Large language models (LLMs) have achieved unprecedented performance by leveraging vast pretraining corpora, yet their performance remains suboptimal in knowledge-intensive domains such as medicine and scientific research, where high factual precision is required. While synthetic data provides a promising avenue for augmenting domain knowledge, existing methods frequently generate redundant samples that do not align with the model's true knowledge gaps. To overcome this limitation, we propose a novel Structural Entropy-guided Knowledge Navigator (SENATOR) framework that addresses the intrinsic knowledge deficiencies of LLMs. Our approach employs the Structure Entropy (SE) metric to quantify uncertainty along knowledge graph paths and leverages Monte Carlo Tree Search (MCTS) to selectively explore regions where the model lacks domain-specific knowledge. Guided by these insights, the framework generates targeted synthetic data for supervised fine-tuning, enabling continuous self-improvement. Experimental results on LLaMA-3 and Qwen2 across multiple domain-specific benchmarks show that SENATOR effectively detects and repairs knowledge deficiencies, achieving notable performance improvements. The code and data for our methods and experiments are available at https://github.com/weiyifan1023/senator.
Agentic systems built on large language models (LLMs) offer promising capabilities for automating complex workflows in healthcare AI. We introduce mAIstro, an open-source, autonomous multi-agentic framework for end-to-end development and deployment of medical AI models. The system orchestrates exploratory data analysis, radiomic feature extraction, image segmentation, classification, and regression through a natural language interface, requiring no coding from the user. Built on a modular architecture, mAIstro supports both open- and closed-source LLMs, and was evaluated using a large and diverse set of prompts across 16 open-source datasets, covering a wide range of imaging modalities, anatomical regions, and data types. The agents successfully executed all tasks, producing interpretable outputs and validated models. This work presents the first agentic framework capable of unifying data analysis, AI model development, and inference across varied healthcare applications, offering a reproducible and extensible foundation for clinical and research AI integration. The code is available at: https://github.com/eltzanis/mAIstro
This study examines the understudied role of algorithmic evaluation of human judgment in hybrid decision-making systems, a critical gap in management research. While extant literature focuses on human reluctance to follow algorithmic advice, we reverse the perspective by investigating how AI agents based on large language models (LLMs) assess and integrate human input. Our work addresses a pressing managerial constraint: firms barred from deploying LLMs directly due to privacy concerns can still leverage them as mediating tools (for instance, anonymized outputs or decision pipelines) to guide high-stakes choices like pricing or discounts without exposing proprietary data. Through a controlled prediction task, we analyze how an LLM-based AI agent weights human versus algorithmic predictions. We find that the AI system systematically discounts human advice, penalizing human errors more severely than algorithmic errors--a bias exacerbated when the agent's identity (human vs AI) is disclosed and the human is positioned second. These results reveal a disconnect between AI-generated trust metrics and the actual influence of human judgment, challenging assumptions about equitable human-AI collaboration. Our findings offer three key contributions. First, we identify a reverse algorithm aversion phenomenon, where AI agents undervalue human input despite comparable error rates. Second, we demonstrate how disclosure and positional bias interact to amplify this effect, with implications for system design. Third, we provide a framework for indirect LLM deployment that balances predictive power with data privacy. For practitioners, this research emphasize the need to audit AI weighting mechanisms, calibrate trust dynamics, and strategically design decision sequences in human-AI systems.
The internet is undergoing a historical transformation from the "Internet of Websites" to the "Internet of AgentSites." While traditional Websites served as the foundation for information hosting and dissemination, a new frontier is emerging where AgentSites serve as the hubs of the internet, where each AgentSite hosts one or more AI agents that receive tasks, address them, and deliver actionable solutions, marking a significant shift in the digital landscape and representing the next generation of online ecosystems. Under this vision, AIOS, the AI Agent Operating System, serves as the server for the development, deployment and execution of AI agents, which is a fundamental infrastructure for the Internet of Agentsites. In this paper, we introduce AIOS Server, a runtime framework to host agents and enable global-scale collaboration among decentralized agents. AIOS Server provides a communication protocol leveraging the Model Context Protocol (MCP) and JSON-RPC to enable agent-agent or human-agent interactions. Each AIOS node operates as a server to host and execute agents, while supporting peer-to-peer coordination without reliance on centralized orchestration. Based on AIOS Server, we further present the world's first practically deployed Internet of Agentsites (AIOS-IoA), including AgentHub for agent registration and discovery and AgentChat for interactive communication, at https://planet.aios.foundation. The agent discovery mechanism based on Distributed Hash Tables (DHT) and a Gossip protocol serves as the search engine for the internet of agentsites. This work provides a practical foundation for building the Internet of Agentsites-a new paradigm where autonomous agents become first-class citizens of the web. The implementation is available at https://github.com/agiresearch/AIOS.Server and is integrated into the AIOS main branch at https://github.com/agiresearch/AIOS.
Multi-agent systems represent a significant advancement in artificial intelligence, enabling complex problem-solving through coordinated specialized agents. However, these systems face fundamental challenges in context management, coordination efficiency, and scalable operation. This paper introduces a comprehensive framework for advancing multi-agent systems through Model Context Protocol (MCP), addressing these challenges through standardized context sharing and coordination mechanisms. We extend previous work on AI agent architectures by developing a unified theoretical foundation, advanced context management techniques, and scalable coordination patterns. Through detailed implementation case studies across enterprise knowledge management, collaborative research, and distributed problem-solving domains, we demonstrate significant performance improvements compared to traditional approaches. Our evaluation methodology provides a systematic assessment framework with benchmark tasks and datasets specifically designed for multi-agent systems. We identify current limitations, emerging research opportunities, and potential transformative applications across industries. This work contributes to the evolution of more capable, collaborative, and context-aware artificial intelligence systems that can effectively address complex real-world challenges.
The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in-silico modeling and reducing dependence on costly experimental trials. Current AI agent-based systems demonstrate proficiency in solving programming challenges and conducting research, indicating an emerging potential to develop software capable of addressing complex problems such as pharmaceutical design and drug discovery. This paper introduces DO Challenge, a benchmark designed to evaluate the decision-making abilities of AI agents in a single, complex problem resembling virtual screening scenarios. The benchmark challenges systems to independently develop, implement, and execute efficient strategies for identifying promising molecular structures from extensive datasets, while navigating chemical space, selecting models, and managing limited resources in a multi-objective context. We also discuss insights from the DO Challenge 2025, a competition based on the proposed benchmark, which showcased diverse strategies explored by human participants. Furthermore, we present the Deep Thought multi-agent system, which demonstrated strong performance on the benchmark, outperforming most human teams. Among the language models tested, Claude 3.7 Sonnet, Gemini 2.5 Pro and o3 performed best in primary agent roles, and GPT-4o, Gemini 2.0 Flash were effective in auxiliary roles. While promising, the system's performance still fell short of expert-designed solutions and showed high instability, highlighting both the potential and current limitations of AI-driven methodologies in transforming drug discovery and broader scientific research.
Most industry-standard generative AIs and feature encoders are proprietary, offering only black-box access: their outputs are observable, but their internal parameters and architectures remain hidden from the end-user. This black-box access is especially limiting when constructing mixture-of-expert type ensemble models since the user cannot optimize each proprietary AI's internal parameters. Our problem naturally lends itself to a non-competitive game-theoretic lens where each proprietary AI (agent) is inherently competing against the other AI agents, with this competition arising naturally due to their obliviousness of the AI's to their internal structure. In contrast, the user acts as a central planner trying to synchronize the ensemble of competing AIs. We show the existence of the unique Nash equilibrium in the online setting, which we even compute in closed-form by eliciting a feedback mechanism between any given time series and the sequence generated by each (proprietary) AI agent. Our solution is implemented as a decentralized, federated-learning algorithm in which each agent optimizes their structure locally on their machine without ever releasing any internal structure to the others. We obtain refined expressions for pre-trained models such as transformers, random feature models, and echo-state networks. Our ``proprietary federated learning'' algorithm is implemented on a range of real-world and synthetic time-series benchmarks. It achieves orders-of-magnitude improvements in predictive accuracy over natural benchmarks, of which there are surprisingly few due to this natural problem still being largely unexplored.
We introduce the In Real Life (IRL) Ditto, an AI-driven embodied agent designed to represent remote colleagues in shared office spaces, creating opportunities for real-time exchanges even in their absence. IRL Ditto offers a unique hybrid experience by allowing in-person colleagues to encounter a digital version of their remote teammates, initiating greetings, updates, or small talk as they might in person. Our research question examines: How can the IRL Ditto influence interactions and relationships among colleagues in a shared office space? Through a four-day study, we assessed IRL Ditto's ability to strengthen social ties by simulating presence and enabling meaningful interactions across different levels of social familiarity. We find that enhancing social relationships depended deeply on the foundation of the relationship participants had with the source of the IRL Ditto. This study provides insights into the role of embodied agents in enriching workplace dynamics for distributed teams.
This paper presents Tinker Tales, an interactive storytelling framework in the format of a board game, designed to support both narrative development and AI literacy in early childhood. The framework integrates tangible and speech-based interactions with AI through NFC chip-attached pawns and tokens, along with a speaker and microphone. Children select and define key story elements-such as characters, places, items, and emotions-using the pawns and tokens, providing further details to the AI and receiving proper assistance, similar to how adults prompt AI for specific tasks (e.g., writing). For evaluation, several game sessions were simulated with a child AI agent, and the quality and safety of the generated stories were assessed from various perspectives. This work highlights the potential of combining physical and digital elements in AI literacy, offering a safe and engaging way for children to learn how to effectively collaborate with AI.
Manus AI is a general-purpose AI agent introduced in early 2025, marking a significant advancement in autonomous artificial intelligence. Developed by the Chinese startup Monica.im, Manus is designed to bridge the gap between "mind" and "hand" - combining the reasoning and planning capabilities of large language models with the ability to execute complex, end-to-end tasks that produce tangible outcomes. This paper presents a comprehensive overview of Manus AI, exploring its core technical architecture, diverse applications across sectors such as healthcare, finance, manufacturing, robotics, and gaming, as well as its key strengths, current limitations, and future potential. Positioned as a preview of what lies ahead, Manus AI represents a shift toward intelligent agents that can translate high-level intentions into real-world actions, heralding a new era of human-AI collaboration.
A voice AI agent that blends seamlessly into daily life would interact with humans in an autonomous, real-time, and emotionally expressive manner. Rather than merely reacting to commands, it would continuously listen, reason, and respond proactively, fostering fluid, dynamic, and emotionally resonant interactions. We introduce Voila, a family of large voice-language foundation models that make a step towards this vision. Voila moves beyond traditional pipeline systems by adopting a new end-to-end architecture that enables full-duplex, low-latency conversations while preserving rich vocal nuances such as tone, rhythm, and emotion. It achieves a response latency of just 195 milliseconds, surpassing the average human response time. Its hierarchical multi-scale Transformer integrates the reasoning capabilities of large language models (LLMs) with powerful acoustic modeling, enabling natural, persona-aware voice generation -- where users can simply write text instructions to define the speaker's identity, tone, and other characteristics. Moreover, Voila supports over one million pre-built voices and efficient customization of new ones from brief audio samples as short as 10 seconds. Beyond spoken dialogue, Voila is designed as a unified model for a wide range of voice-based applications, including automatic speech recognition (ASR), Text-to-Speech (TTS), and, with minimal adaptation, multilingual speech translation. Voila is fully open-sourced to support open research and accelerate progress toward next-generation human-machine interactions.
We present Noise-to-Meaning Recursive Self-Improvement (N2M-RSI), a minimal formal model showing that once an AI agent feeds its own outputs back as inputs and crosses an explicit information-integration threshold, its internal complexity will grow without bound under our assumptions. The framework unifies earlier ideas on self-prompting large language models, G\"odelian self-reference, and AutoML, yet remains implementation-agnostic. The model furthermore scales naturally to interacting swarms of agents, hinting at super-linear effects once communication among instances is permitted. For safety reasons, we omit system-specific implementation details and release only a brief, model-agnostic toy prototype in Appendix C.