Deep Neural Networks~(DNNs) have been widely deployed in software to address various tasks~(e.g., autonomous driving, medical diagnosis). However, they could also produce incorrect behaviors that result in financial losses and even threaten human safety. To reveal the incorrect behaviors in DNN and repair them, DNN developers often collect rich unlabeled datasets from the natural world and label them to test the DNN models. However, properly labeling a large number of unlabeled datasets is a highly expensive and time-consuming task. To address the above-mentioned problem, we propose NSS, Neuron Sensitivity guided test case Selection, which can reduce the labeling time by selecting valuable test cases from unlabeled datasets. NSS leverages the internal neuron's information induced by test cases to select valuable test cases, which have high confidence in causing the model to behave incorrectly. We evaluate NSS with four widely used datasets and four well-designed DNN models compared to SOTA baseline methods. The results show that NSS performs well in assessing the test cases' probability of fault triggering and model improvement capabilities. Specifically, compared with baseline approaches, NSS obtains a higher fault detection rate~(e.g., when selecting 5\% test case from the unlabeled dataset in MNIST \& LeNet1 experiment, NSS can obtain 81.8\% fault detection rate, 20\% higher than baselines).
We wish to define the limits of a classical classification model based on deep learning when applied to abstract images, which do not represent visually identifiable objects.QR codes (Quick Response codes) fall into this category of abstract images: one bit corresponding to one encoded character, QR codes were not designed to be decoded manually. To understand the limitations of a deep learning-based model for abstract image classification, we train an image classification model on QR codes generated from information obtained when reading a health pass. We compare a classification model with a classical (deterministic) decoding method in the presence of noise. This study allows us to conclude that a model based on deep learning can be relevant for the understanding of abstract images.
Explainable Deep Learning has gained significant attention in the field of artificial intelligence (AI), particularly in domains such as medical imaging, where accurate and interpretable machine learning models are crucial for effective diagnosis and treatment planning. Grad-CAM is a baseline that highlights the most critical regions of an image used in a deep learning model's decision-making process, increasing interpretability and trust in the results. It is applied in many computer vision (CV) tasks such as classification and explanation. This study explores the principles of Explainable Deep Learning and its relevance to medical imaging, discusses various explainability techniques and their limitations, and examines medical imaging applications of Grad-CAM. The findings highlight the potential of Explainable Deep Learning and Grad-CAM in improving the accuracy and interpretability of deep learning models in medical imaging. The code is available in (will be available).
Eye is the essential sense organ for vision function. Due to the fact that certain eye disorders might result in vision loss, it is essential to diagnose and treat eye diseases early on. By identifying common eye illnesses and performing an eye check, eye care providers can safeguard patients against vision loss or blindness. Convolutional neural networks (CNN) and transfer learning were employed in this study to discriminate between a normal eye and one with diabetic retinopathy, cataract, or glaucoma disease. Using transfer learning for multi-class classification, high accuracy was achieved at 94% while the traditional CNN achieved 84% rate.
Mammography images are widely used to detect non-palpable breast lesions or nodules, preventing cancer and providing the opportunity to plan interventions when necessary. The identification of some structures of interest is essential to make a diagnosis and evaluate image adequacy. Thus, computer-aided detection systems can be helpful in assisting medical interpretation by automatically segmenting these landmark structures. In this paper, we propose a deep learning-based framework for the segmentation of the nipple, the pectoral muscle, the fibroglandular tissue, and the fatty tissue on standard-view mammography images. We introduce a large private segmentation dataset and extensive experiments considering different deep-learning model architectures. Our experiments demonstrate accurate segmentation performance on variate and challenging cases, showing that this framework can be integrated into clinical practice.
Image synthesis has attracted emerging research interests in academic and industry communities. Deep learning technologies especially the generative models greatly inspired controllable image synthesis approaches and applications, which aim to generate particular visual contents with latent prompts. In order to further investigate low-level controllable image synthesis problem which is crucial for fine image rendering and editing tasks, we present a survey of some recent works on 3D controllable image synthesis using deep learning. We first introduce the datasets and evaluation indicators for 3D controllable image synthesis. Then, we review the state-of-the-art research for geometrically controllable image synthesis in two aspects: 1) Viewpoint/pose-controllable image synthesis; 2) Structure/shape-controllable image synthesis. Furthermore, the photometrically controllable image synthesis approaches are also reviewed for 3D re-lighting researches. While the emphasis is on 3D controllable image synthesis algorithms, the related applications, products and resources are also briefly summarized for practitioners.
In this endeavor, we developed a comprehensive system that processes integrated visual features derived from video frames captured by a regular camera, along with depth details obtained from a point cloud scanner. This system is designed to anticipate driving actions, encompassing both vehicle speed and steering angle. To ensure its reliability, we conducted assessments where we juxtaposed the projected outcomes with the established norms adhered to by skilled real-world drivers. Our evaluation outcomes indicate that the forecasts achieve a noteworthy level of accuracy in a minimum of half the test scenarios (ranging around 50-80%, contingent on the specific model). Notably, the utilization of amalgamated features yielded superior performance in comparison to using video frames in isolation, as demonstrated by most of the cases.
Myocardial infarction (MI) is one of the most common causes of death in the world. Image-based biomarkers commonly used in the clinic, such as ejection fraction, fail to capture more complex patterns in the heart's 3D anatomy and thus limit diagnostic accuracy. In this work, we present the multi-objective point cloud autoencoder as a novel geometric deep learning approach for explainable infarction prediction, based on multi-class 3D point cloud representations of cardiac anatomy and function. Its architecture consists of multiple task-specific branches connected by a low-dimensional latent space to allow for effective multi-objective learning of both reconstruction and MI prediction, while capturing pathology-specific 3D shape information in an interpretable latent space. Furthermore, its hierarchical branch design with point cloud-based deep learning operations enables efficient multi-scale feature learning directly on high-resolution anatomy point clouds. In our experiments on a large UK Biobank dataset, the multi-objective point cloud autoencoder is able to accurately reconstruct multi-temporal 3D shapes with Chamfer distances between predicted and input anatomies below the underlying images' pixel resolution. Our method outperforms multiple machine learning and deep learning benchmarks for the task of incident MI prediction by 19% in terms of Area Under the Receiver Operating Characteristic curve. In addition, its task-specific compact latent space exhibits easily separable control and MI clusters with clinically plausible associations between subject encodings and corresponding 3D shapes, thus demonstrating the explainability of the prediction.
Deep Learning (DL) , a variant of the neural network algorithms originally proposed in the 1980s, has made surprising progress in Artificial Intelligence (AI), ranging from language translation, protein folding, autonomous cars, and more recently human-like language models (CHATbots), all that seemed intractable until very recently. Despite the growing use of Deep Learning (DL) networks, little is actually understood about the learning mechanisms and representations that makes these networks effective across such a diverse range of applications. Part of the answer must be the huge scale of the architecture and of course the large scale of the data, since not much has changed since 1987. But the nature of deep learned representations remain largely unknown. Unfortunately training sets with millions or billions of tokens have unknown combinatorics and Networks with millions or billions of hidden units cannot easily be visualized and their mechanisms cannot be easily revealed. In this paper, we explore these questions with a large (1.24M weights; VGG) DL in a novel high density sample task (5 unique tokens with at minimum 500 exemplars per token) which allows us to more carefully follow the emergence of category structure and feature construction. We use various visualization methods for following the emergence of the classification and the development of the coupling of feature detectors and structures that provide a type of graphical bootstrapping, From these results we harvest some basic observations of the learning dynamics of DL and propose a new theory of complex feature construction based on our results.
Can artificial intelligence unlock the secrets of the human brain? How do the inner mechanisms of deep learning models relate to our neural circuits? Is it possible to enhance AI by tapping into the power of brain recordings? These captivating questions lie at the heart of an emerging field at the intersection of neuroscience and artificial intelligence. Our survey dives into this exciting domain, focusing on human brain recording studies and cutting-edge cognitive neuroscience datasets that capture brain activity during natural language processing, visual perception, and auditory experiences. We explore two fundamental approaches: encoding models, which attempt to generate brain activity patterns from sensory inputs; and decoding models, which aim to reconstruct our thoughts and perceptions from neural signals. These techniques not only promise breakthroughs in neurological diagnostics and brain-computer interfaces but also offer a window into the very nature of cognition. In this survey, we first discuss popular representations of language, vision, and speech stimuli, and present a summary of neuroscience datasets. We then review how the recent advances in deep learning transformed this field, by investigating the popular deep learning based encoding and decoding architectures, noting their benefits and limitations across different sensory modalities. From text to images, speech to videos, we investigate how these models capture the brain's response to our complex, multimodal world. While our primary focus is on human studies, we also highlight the crucial role of animal models in advancing our understanding of neural mechanisms. Throughout, we mention the ethical implications of these powerful technologies, addressing concerns about privacy and cognitive liberty. We conclude with a summary and discussion of future trends in this rapidly evolving field.
The field of RNA secondary structure prediction has made significant progress with the adoption of deep learning techniques. In this work, we present the RNAformer, a lean deep learning model using axial attention and recycling in the latent space. We gain performance improvements by designing the architecture for modeling the adjacency matrix directly in the latent space and by scaling the size of the model. Our approach achieves state-of-the-art performance on the popular TS0 benchmark dataset and even outperforms methods that use external information. Further, we show experimentally that the RNAformer can learn a biophysical model of the RNA folding process.
Deep learning (DL) models have been popular due to their ability to learn directly from the raw data in an end-to-end paradigm, alleviating the concern of a separate error-prone feature extraction phase. Recent DL-based neuroimaging studies have also witnessed a noticeable performance advancement over traditional machine learning algorithms. But the challenges of deep learning models still exist because of the lack of transparency in these models for their successful deployment in real-world applications. In recent years, Explainable AI (XAI) has undergone a surge of developments mainly to get intuitions of how the models reached the decisions, which is essential for safety-critical domains such as healthcare, finance, and law enforcement agencies. While the interpretability domain is advancing noticeably, researchers are still unclear about what aspect of model learning a post hoc method reveals and how to validate its reliability. This paper comprehensively reviews interpretable deep learning models in the neuroimaging domain. Firstly, we summarize the current status of interpretability resources in general, focusing on the progression of methods, associated challenges, and opinions. Secondly, we discuss how multiple recent neuroimaging studies leveraged model interpretability to capture anatomical and functional brain alterations most relevant to model predictions. Finally, we discuss the limitations of the current practices and offer some valuable insights and guidance on how we can steer our future research directions to make deep learning models substantially interpretable and thus advance scientific understanding of brain disorders.
Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and technology as a consequence of several effects including dimensionality reduction(3D to 2D), noise, reflections, shades, and occlusions, among many other possibilities. While a large number of interesting related approaches have been suggested along the last decades, it was mainly thanks to the recent development of deep learning that more effective and general solutions have been obtained, currently constituting the basic comparison reference for this type of operation. Also developed recently, a multiset-based methodology has been described that is capable of encouraging image segmentation performance combining spatial accuracy, stability, and robustness while requiring little computational resources (hardware and/or training and recognition time). The interesting features of the multiset neurons methodology mostly follow from the enhanced selectivity and sensitivity, as well as good robustness to data perturbations and outliers, allowed by the coincidence similarity index on which the multiset approach to supervised image segmentation is founded. After describing the deep learning and multiset neurons approaches, the present work develops comparison experiments between them which are primarily aimed at illustrating their respective main interesting features when applied to the adopted specific type of data and parameter configurations. While the deep learning approach confirmed its potential for performing image segmentation, the alternative multiset methodology allowed for enhanced accuracy while requiring little computational resources.
In recent years, there has been an explosion of research on the application of deep learning to the prediction of various peptide properties, due to the significant development and market potential of peptides. Molecular dynamics has enabled the efficient collection of large peptide datasets, providing reliable training data for deep learning. However, the lack of systematic analysis of the peptide encoding, which is essential for AI-assisted peptide-related tasks, makes it an urgent problem to be solved for the improvement of prediction accuracy. To address this issue, we first collect a high-quality, colossal simulation dataset of peptide self-assembly containing over 62,000 samples generated by coarse-grained molecular dynamics (CGMD). Then, we systematically investigate the effect of peptide encoding of amino acids into sequences and molecular graphs using state-of-the-art sequential (i.e., RNN, LSTM, and Transformer) and structural deep learning models (i.e., GCN, GAT, and GraphSAGE), on the accuracy of peptide self-assembly prediction, an essential physiochemical process prior to any peptide-related applications. Extensive benchmarking studies have proven Transformer to be the most powerful sequence-encoding-based deep learning model, pushing the limit of peptide self-assembly prediction to decapeptides. In summary, this work provides a comprehensive benchmark analysis of peptide encoding with advanced deep learning models, serving as a guide for a wide range of peptide-related predictions such as isoelectric points, hydration free energy, etc.
Forecasting how landslides will evolve over time or whether they will fail is a challenging task due to a variety of factors, both internal and external. Despite their considerable potential to address these challenges, deep learning techniques lack interpretability, undermining the credibility of the forecasts they produce. The recent development of transformer-based deep learning offers untapped possibilities for forecasting landslides with unprecedented interpretability and nonlinear feature learning capabilities. Here, we present a deep learning pipeline that is capable of predicting landslide behavior holistically, which employs a transformer-based network called LFIT to learn complex nonlinear relationships from prior knowledge and multiple source data, identifying the most relevant variables, and demonstrating a comprehensive understanding of landslide evolution and temporal patterns. By integrating prior knowledge, we provide improvement in holistic landslide forecasting, enabling us to capture diverse responses to various influencing factors in different local landslide areas. Using deformation observations as proxies for measuring the kinetics of landslides, we validate our approach by training models to forecast reservoir landslides in the Three Gorges Reservoir and creeping landslides on the Tibetan Plateau. When prior knowledge is incorporated, we show that interpretable landslide forecasting effectively identifies influential factors across various landslides. It further elucidates how local areas respond to these factors, making landslide behavior and trends more interpretable and predictable. The findings from this study will contribute to understanding landslide behavior in a new way and make the proposed approach applicable to other complex disasters influenced by internal and external factors in the future.
Many companies and organizations have started to use some form of AIenabled auto mated tools to assist in their hiring process, e.g. screening resumes, interviewing candi dates, performance evaluation. While those AI tools have greatly improved human re source operations efficiency and provided conveniences to job seekers as well, there are increasing concerns on unfair treatment to candidates, caused by underlying bias in AI systems. Laws around equal opportunity and fairness, like GDPR, CCPA, are introduced or under development, in attempt to regulate AI. However, it is difficult to implement AI regulations in practice, as technologies are constantly advancing and the risk perti nent to their applications can fail to be recognized. This study examined deep learning methods, a recent technology breakthrough, with focus on their application to automated resume screening. One impressive performance of deep learning methods is the represen tation of individual words as lowdimensional numerical vectors, called word embedding, which are learned from aggregated global wordword cooccurrence statistics from a cor pus, like Wikipedia or Google news. The resulting word representations possess interest ing linear substructures of the word vector space and have been widely used in down stream tasks, like resume screening. However, word embedding inherits and reinforces the stereotyping from the training corpus, as deep learning models essentially learn a probability distribution of words and their relations from history data. Our study finds out that if we rely on such deeplearningpowered automated resume screening tools, it may lead to decisions favoring or disfavoring certain demographic groups and raise eth ical, even legal, concerns. To address the issue, we developed bias mitigation method. Extensive experiments on real candidate resumes are conducted to validate our study
Optical information processing and computing can potentially offer enhanced performance, scalability and energy efficiency. However, achieving nonlinearity-a critical component of computation-remains challenging in the optical domain. Here we introduce a design that leverages a multiple-scattering cavity to passively induce optical nonlinear random mapping with a continuous-wave laser at a low power. Each scattering event effectively mixes information from different areas of a spatial light modulator, resulting in a highly nonlinear mapping between the input data and output pattern. We demonstrate that our design retains vital information even when the readout dimensionality is reduced, thereby enabling optical data compression. This capability allows our optical platforms to offer efficient optical information processing solutions across applications. We demonstrate our design's efficacy across tasks, including classification, image reconstruction, keypoint detection and object detection, all of which are achieved through optical data compression combined with a digital decoder. In particular, high performance at extreme compression ratios is observed in real-time pedestrian detection. Our findings open pathways for novel algorithms and unconventional architectural designs for optical computing.
It is imperative to ensure the robustness of deep learning models in critical applications such as, healthcare. While recent advances in deep learning have improved the performance of volumetric medical image segmentation models, these models cannot be deployed for real-world applications immediately due to their vulnerability to adversarial attacks. We present a 3D frequency domain adversarial attack for volumetric medical image segmentation models and demonstrate its advantages over conventional input or voxel domain attacks. Using our proposed attack, we introduce a novel frequency domain adversarial training approach for optimizing a robust model against voxel and frequency domain attacks. Moreover, we propose frequency consistency loss to regulate our frequency domain adversarial training that achieves a better tradeoff between model's performance on clean and adversarial samples. Code is publicly available at https://github.com/asif-hanif/vafa.
Over the last decade, there has been a vast increase in eating disorder diagnoses and eating disorder-attributed deaths, reaching their zenith during the Covid-19 pandemic. This immense growth derived in part from the stressors of the pandemic but also from increased exposure to social media, which is rife with content that promotes eating disorders. This study aimed to create a multimodal deep learning model that can determine if a given social media post promotes eating disorders based on a combination of visual and textual data. A labeled dataset of Tweets was collected from Twitter, recently rebranded as X, upon which twelve deep learning models were trained and evaluated. Based on model performance, the most effective deep learning model was the multimodal fusion of the RoBERTa natural language processing model and the MaxViT image classification model, attaining accuracy and F1 scores of 95.9% and 0.959, respectively. The RoBERTa and MaxViT fusion model, deployed to classify an unlabeled dataset of posts from the social media sites Tumblr and Reddit, generated results akin to those of previous research studies that did not employ artificial intelligence-based techniques, indicating that deep learning models can develop insights congruent to those of researchers. Additionally, the model was used to conduct a time-series analysis of yet unseen Tweets from eight Twitter hashtags, uncovering that, since 2014, the relative abundance of content that promotes eating disorders has decreased drastically within those communities. Despite this reduction, by 2018, content that promotes eating disorders had either stopped declining or increased in ampleness anew on those hashtags.
In this paper, we propose a numerical methodology for finding the closed-loop Nash equilibrium of stochastic delay differential games through deep learning. These games are prevalent in finance and economics where multi-agent interaction and delayed effects are often desired features in a model, but are introduced at the expense of increased dimensionality of the problem. This increased dimensionality is especially significant as that arising from the number of players is coupled with the potential infinite dimensionality caused by the delay. Our approach involves parameterizing the controls of each player using distinct recurrent neural networks. These recurrent neural network-based controls are then trained using a modified version of Brown's fictitious play, incorporating deep learning techniques. To evaluate the effectiveness of our methodology, we test it on finance-related problems with known solutions. Furthermore, we also develop new problems and derive their analytical Nash equilibrium solutions, which serve as additional benchmarks for assessing the performance of our proposed deep learning approach.