Quality-Governed Deep Learning Network for Brain Tumor MRI Segmentation

원문 초록

The segmentation of brain tumors from magnetic resonance imaging (MRI) is an essential step for computer-aided neuro-oncology, treatment planning and follow-up. While effective encoder-decoder representations are achieved by U-Net and Attention U-Net, the skip sections of the network can generate weak-contrast or noisy responses in the case of heterogeneous boundaries of the tumor. In this paper, we introduce a Quality-Governed Deep Learning Network (QGDL-Net) that can be used for binary tumor segmentation from FLAIR MRI slices. The proposed model is able to predict the slice quality based on contrast and SNR statistics and to fine-tune the encoder features prior to decoding by learnable quality gates. We used the 80:20 train-validation split for experiments with BraTS 2021. QGDL-Net achieved a Dice of 0.9747, IoU of 0.9506, precision of 0.9755, recall of 0.9739, F1 of 0.9747 and accuracy of 0.9982, outperforming U-Net and Attention U-Net. The EigenCAM maps and segmentation overlays provide better tumor localization and interpretable activation around the lesion regions.