Echo-SyncNet: Self-supervised Cardiac View Synchronization in Echocardiography

원문 초록

In echocardiography (echo), an electrocardiogram (ECG) is conventionally used to temporally align different cardiac views for assessing critical measurements. However, in emergencies or point-of-care situations, acquiring an ECG is often not an option, hence motivating the need for alternative temporal synchronization methods. Here, we propose Echo-SyncNet, a self-supervised learning framework to synchronize various cross-sectional 2D echo series without any external input. The proposed framework takes advantage of both intra-view and inter-view self supervisions. The former relies on spatiotemporal patterns found between the frames of a single echo cine and the latter on the interdependencies between multiple cines. The combined supervisions are used to learn a feature-rich embedding space where multiple echo cines can be temporally synchronized. We evaluate the framework with multiple experiments: 1) Using data from 998 patients, Echo-SyncNet shows promising results for synchronizing Apical 2 chamber and Apical 4 chamber cardiac views; 2) Using data from 3070 patients, our experiments reveal that the learned representations of Echo-SyncNet outperform a supervised deep learning method that is optimized for automatic detection of fine-grained cardiac phase; 3) We show the usefulness of the learned representations in a one-shot learning scenario of cardiac keyframe detection. Without any fine-tuning, keyframes in 1188 validation patient studies are identified by synchronizing them with only one labeled reference study. We do not make any prior assumption about what specific cardiac views are used for training and show that Echo-SyncNet can accurately generalize to views not present in its training set. Project repository: github.com/fatemehtd/Echo-SyncNet.