Contrastive Language-Image Pretraining (CLIP) has demonstrated strong zero-shot performance across diverse downstream text-image tasks. Existing CLIP methods typically optimize a contrastive objective using negative samples drawn from each minibatch. To achieve robust representation learning, these methods require extremely large batch sizes and escalate computational demands to hundreds or even thousands of GPUs. Prior approaches to mitigate this issue often compromise downstream performance, prolong training duration, or face scalability challenges with very large datasets. To overcome these limitations, we propose AmorLIP, an efficient CLIP pretraining framework that amortizes expensive computations involved in contrastive learning through lightweight neural networks, which substantially improves training efficiency and performance. Leveraging insights from a spectral factorization of energy-based models, we introduce novel amortization objectives along with practical techniques to improve training stability. Extensive experiments across 38 downstream tasks demonstrate the superior zero-shot classification and retrieval capabilities of AmorLIP, consistently outperforming standard CLIP baselines with substantial relative improvements of up to 12.24%.
Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated training data. However, the pixel-level annotation process is expensive, time-consuming, and error-prone, hindering progress and making it challenging to perform effective segmentations. Therefore, models must learn efficiently from limited labeled data. Self-supervised learning (SSL), particularly contrastive learning via pre-training on unlabeled data and fine-tuning on limited annotations, can facilitate such limited labeled image segmentation. To this end, we propose a novel self-supervised contrastive learning framework for medical image segmentation, leveraging inherent relationships of different images, dubbed PolyCL. Without requiring any pixel-level annotations or unreasonable data augmentations, our PolyCL learns and transfers context-aware discriminant features useful for segmentation from an innovative surrogate, in a task-related manner. Additionally, we integrate the Segment Anything Model (SAM) into our framework in two novel ways: as a post-processing refinement module that improves the accuracy of predicted masks using bounding box prompts derived from coarse outputs, and as a propagation mechanism via SAM 2 that generates volumetric segmentations from a single annotated 2D slice. Experimental evaluations on three public computed tomography (CT) datasets demonstrate that PolyCL outperforms fully-supervised and self-supervised baselines in both low-data and cross-domain scenarios. Our code is available at https://github.com/tbwa233/PolyCL.
Diffusion Tensor Imaging (DTI) tractography offers detailed insights into the structural connectivity of the brain, but presents challenges in effective representation and interpretation in deep learning models. In this work, we propose a novel 2D representation of DTI tractography that encodes tract-level fractional anisotropy (FA) values into a 9x9 grayscale image. This representation is processed through a Beta-Total Correlation Variational Autoencoder with a Spatial Broadcast Decoder to learn a disentangled and interpretable latent embedding. We evaluate the quality of this embedding using supervised and unsupervised representation learning strategies, including auxiliary classification, triplet loss, and SimCLR-based contrastive learning. Compared to the 1D Group deep neural network (DNN) baselines, our approach improves the F1 score in a downstream sex classification task by 15.74% and shows a better disentanglement than the 3D representation.
Weakly supervised referring expression comprehension(WREC) and segmentation(WRES) aim to learn object grounding based on a given expression using weak supervision signals like image-text pairs. While these tasks have traditionally been modeled separately, we argue that they can benefit from joint learning in a multi-task framework. To this end, we propose WeakMCN, a novel multi-task collaborative network that effectively combines WREC and WRES with a dual-branch architecture. Specifically, the WREC branch is formulated as anchor-based contrastive learning, which also acts as a teacher to supervise the WRES branch. In WeakMCN, we propose two innovative designs to facilitate multi-task collaboration, namely Dynamic Visual Feature Enhancement(DVFE) and Collaborative Consistency Module(CCM). DVFE dynamically combines various pre-trained visual knowledge to meet different task requirements, while CCM promotes cross-task consistency from the perspective of optimization. Extensive experimental results on three popular REC and RES benchmarks, i.e., RefCOCO, RefCOCO+, and RefCOCOg, consistently demonstrate performance gains of WeakMCN over state-of-the-art single-task alternatives, e.g., up to 3.91% and 13.11% on RefCOCO for WREC and WRES tasks, respectively. Furthermore, experiments also validate the strong generalization ability of WeakMCN in both semi-supervised REC and RES settings against existing methods, e.g., +8.94% for semi-REC and +7.71% for semi-RES on 1% RefCOCO. The code is publicly available at https://github.com/MRUIL/WeakMCN.
Image Restoration (IR) aims to recover high quality images from degraded inputs affected by various corruptions such as noise, blur, haze, rain, and low light conditions. Despite recent advances, most existing approaches treat IR as a direct mapping problem, relying on shared representations across degradation types without modeling their structural diversity. In this work, we present MIRAGE, a unified and lightweight framework for all in one IR that explicitly decomposes the input feature space into three semantically aligned parallel branches, each processed by a specialized module attention for global context, convolution for local textures, and MLP for channel-wise statistics. This modular decomposition significantly improves generalization and efficiency across diverse degradations. Furthermore, we introduce a cross layer contrastive learning scheme that aligns shallow and latent features to enhance the discriminability of shared representations. To better capture the underlying geometry of feature representations, we perform contrastive learning in a Symmetric Positive Definite (SPD) manifold space rather than the conventional Euclidean space. Extensive experiments show that MIRAGE not only achieves new state of the art performance across a variety of degradation types but also offers a scalable solution for challenging all-in-one IR scenarios. Our code and models will be publicly available at https://amazingren.github.io/MIRAGE/.
Multimodal information retrieval (MIR) faces inherent challenges due to the heterogeneity of data sources and the complexity of cross-modal alignment. While previous studies have identified modal gaps in feature spaces, a systematic approach to address these challenges remains unexplored. In this work, we introduce UNITE, a universal framework that tackles these challenges through two critical yet underexplored aspects: data curation and modality-aware training configurations. Our work provides the first comprehensive analysis of how modality-specific data properties influence downstream task performance across diverse scenarios. Moreover, we propose Modal-Aware Masked Contrastive Learning (MAMCL) to mitigate the competitive relationships among the instances of different modalities. Our framework achieves state-of-the-art results on multiple multimodal retrieval benchmarks, outperforming existing methods by notable margins. Through extensive experiments, we demonstrate that strategic modality curation and tailored training protocols are pivotal for robust cross-modal representation learning. This work not only advances MIR performance but also provides a foundational blueprint for future research in multimodal systems. Our project is available at https://friedrichor.github.io/projects/UNITE.
Implicit hate speech detection is challenging due to its subtlety and reliance on contextual interpretation rather than explicit offensive words. Current approaches rely on contrastive learning, which are shown to be effective on distinguishing hate and non-hate sentences. Humans, however, detect implicit hate speech by first identifying specific targets within the text and subsequently interpreting how these target relate to their surrounding context. Motivated by this reasoning process, we propose AmpleHate, a novel approach designed to mirror human inference for implicit hate detection. AmpleHate identifies explicit target using a pretrained Named Entity Recognition model and capture implicit target information via [CLS] tokens. It computes attention-based relationships between explicit, implicit targets and sentence context and then, directly injects these relational vectors into the final sentence representation. This amplifies the critical signals of target-context relations for determining implicit hate. Experiments demonstrate that AmpleHate achieves state-of-the-art performance, outperforming contrastive learning baselines by an average of 82.14% and achieve faster convergence. Qualitative analyses further reveal that attention patterns produced by AmpleHate closely align with human judgement, underscoring its interpretability and robustness.
Learning effective visual representations for robotic manipulation remains a fundamental challenge due to the complex body dynamics involved in action execution. In this paper, we study how visual representations that carry body-relevant cues can enable efficient policy learning for downstream robotic manipulation tasks. We present $\textbf{I}$nter-token $\textbf{Con}$trast ($\textbf{ICon}$), a contrastive learning method applied to the token-level representations of Vision Transformers (ViTs). ICon enforces a separation in the feature space between agent-specific and environment-specific tokens, resulting in agent-centric visual representations that embed body-specific inductive biases. This framework can be seamlessly integrated into end-to-end policy learning by incorporating the contrastive loss as an auxiliary objective. Our experiments show that ICon not only improves policy performance across various manipulation tasks but also facilitates policy transfer across different robots. The project website: https://github.com/HenryWJL/icon
Earth observation foundation models have shown strong generalization across multiple Earth observation tasks, but their robustness under real-world perturbations remains underexplored. To bridge this gap, we introduce REOBench, the first comprehensive benchmark for evaluating the robustness of Earth observation foundation models across six tasks and twelve types of image corruptions, including both appearance-based and geometric perturbations. To ensure realistic and fine-grained evaluation, our benchmark focuses on high-resolution optical remote sensing images, which are widely used in critical applications such as urban planning and disaster response. We conduct a systematic evaluation of a broad range of models trained using masked image modeling, contrastive learning, and vision-language pre-training paradigms. Our results reveal that (1) existing Earth observation foundation models experience significant performance degradation when exposed to input corruptions. (2) The severity of degradation varies across tasks, model architectures, backbone sizes, and types of corruption, with performance drop varying from less than 1% to over 20%. (3) Vision-language models show enhanced robustness, particularly in multimodal tasks. REOBench underscores the vulnerability of current Earth observation foundation models to real-world corruptions and provides actionable insights for developing more robust and reliable models.
Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but lack the structural knowledge essential for many biological applications. To address this, we integrate structural insights from pre-trained protein graph neural networks (pGNNs) into pLMs through a latent-level contrastive learning task. This task aligns residue representations from pLMs with those from pGNNs across multiple proteins, enriching pLMs with inter-protein structural knowledge. Additionally, we incorporate a physical-level task that infuses intra-protein structural knowledge by optimizing pLMs to predict structural tokens. The proposed dual-task framework effectively incorporates both inter-protein and intra-protein structural knowledge into pLMs. Given the variability in the quality of protein structures in PDB, we further introduce a residue loss selection module, which uses a small model trained on high-quality structures to select reliable yet challenging residue losses for the pLM to learn. Applying our structure alignment method to the state-of-the-art ESM2 and AMPLIFY results in notable performance gains across a wide range of tasks, including a 12.7% increase in ESM2 contact prediction. The data, code, and resulting SaESM2 and SaAMPLIFY models will be released on Hugging Face.
Sequencing a genome to determine an individual's DNA produces an enormous number of short nucleotide subsequences known as reads, which must be reassembled to reconstruct the full genome. We present a method for analyzing this type of data using contrastive learning, in which an encoder model is trained to produce embeddings that cluster together sequences from the same genomic region. The sequential nature of genomic regions is preserved in the form of trajectories through this embedding space. Trained solely to reflect the structure of the genome, the resulting model provides a general representation of $k$-mer sequences, suitable for a range of downstream tasks involving read data. We apply our framework to learn the structure of the $E.\ coli$ genome, and demonstrate its use in simulated ancient DNA (aDNA) read mapping and identification of structural variations. Furthermore, we illustrate the potential of using this type of model for metagenomic species identification. We show how incorporating a domain-specific noise model can enhance embedding robustness, and how a supervised contrastive learning setting can be adopted when a linear reference genome is available, by introducing a distance thresholding parameter $\Gamma$. The model can also be trained fully self-supervised on read data, enabling analysis without the need to construct a full genome assembly using specialized algorithms. Small prediction heads based on a pre-trained embedding are shown to perform on par with BWA-aln, the current gold standard approach for aDNA mapping, in terms of accuracy and runtime for short genomes. Given the method's favorable scaling properties with respect to total genome size, inference using our approach is highly promising for metagenomic applications and for mapping to genomes comparable in size to the human genome.
Despite providing superior performance, open-source large language models (LLMs) are vulnerable to abusive usage. To address this issue, recent works propose LLM fingerprinting methods to identify the specific source LLMs behind suspect applications. However, these methods fail to provide stealthy and robust fingerprint verification. In this paper, we propose a novel LLM fingerprinting scheme, namely CoTSRF, which utilizes the Chain of Thought (CoT) as the fingerprint of an LLM. CoTSRF first collects the responses from the source LLM by querying it with crafted CoT queries. Then, it applies contrastive learning to train a CoT extractor that extracts the CoT feature (i.e., fingerprint) from the responses. Finally, CoTSRF conducts fingerprint verification by comparing the Kullback-Leibler divergence between the CoT features of the source and suspect LLMs against an empirical threshold. Various experiments have been conducted to demonstrate the advantage of our proposed CoTSRF for fingerprinting LLMs, particularly in stealthy and robust fingerprint verification.
Customizable multilingual zero-shot singing voice synthesis (SVS) has various potential applications in music composition and short video dubbing. However, existing SVS models overly depend on phoneme and note boundary annotations, limiting their robustness in zero-shot scenarios and producing poor transitions between phonemes and notes. Moreover, they also lack effective multi-level style control via diverse prompts. To overcome these challenges, we introduce TCSinger 2, a multi-task multilingual zero-shot SVS model with style transfer and style control based on various prompts. TCSinger 2 mainly includes three key modules: 1) Blurred Boundary Content (BBC) Encoder, predicts duration, extends content embedding, and applies masking to the boundaries to enable smooth transitions. 2) Custom Audio Encoder, uses contrastive learning to extract aligned representations from singing, speech, and textual prompts. 3) Flow-based Custom Transformer, leverages Cus-MOE, with F0 supervision, enhancing both the synthesis quality and style modeling of the generated singing voice. Experimental results show that TCSinger 2 outperforms baseline models in both subjective and objective metrics across multiple related tasks. Singing voice samples are available at https://aaronz345.github.io/TCSinger2Demo/.
Graph contrastive learning (GCL) has demonstrated great promise for learning generalizable graph representations from unlabeled data. However, conventional GCL approaches face two critical limitations: (1) the restricted expressive capacity of multilayer perceptron (MLP) based encoders, and (2) suboptimal negative samples that either from random augmentations-failing to provide effective 'hard negatives'-or generated hard negatives without addressing the semantic distinctions crucial for discriminating graph data. To this end, we propose Khan-GCL, a novel framework that integrates the Kolmogorov-Arnold Network (KAN) into the GCL encoder architecture, substantially enhancing its representational capacity. Furthermore, we exploit the rich information embedded within KAN coefficient parameters to develop two novel critical feature identification techniques that enable the generation of semantically meaningful hard negative samples for each graph representation. These strategically constructed hard negatives guide the encoder to learn more discriminative features by emphasizing critical semantic differences between graphs. Extensive experiments demonstrate that our approach achieves state-of-the-art performance compared to existing GCL methods across a variety of datasets and tasks.
Deploying machine learning models in resource-constrained environments, such as edge devices or rapid prototyping scenarios, increasingly demands distillation of large datasets into significantly smaller yet informative synthetic datasets. Current dataset distillation techniques, particularly Trajectory Matching methods, optimize synthetic data so that the model's training trajectory on synthetic samples mirrors that on real data. While demonstrating efficacy on medium-scale synthetic datasets, these methods fail to adequately preserve semantic richness under extreme sample scarcity. To address this limitation, we propose a novel dataset distillation method integrating contrastive learning during image synthesis. By explicitly maximizing instance-level feature discrimination, our approach produces more informative and diverse synthetic samples, even when dataset sizes are significantly constrained. Experimental results demonstrate that incorporating contrastive learning substantially enhances the performance of models trained on very small-scale synthetic datasets. This integration not only guides more effective feature representation but also significantly improves the visual fidelity of the synthesized images. Experimental results demonstrate that our method achieves notable performance improvements over existing distillation techniques, especially in scenarios with extremely limited synthetic data.
Vision-Language Models (VLMs) are essential for multimodal tasks, especially compositional reasoning (CR) tasks, which require distinguishing fine-grained semantic differences between visual and textual embeddings. However, existing methods primarily fine-tune the model by generating text-based hard negative samples, neglecting the importance of image-based negative samples, which results in insufficient training of the visual encoder and ultimately impacts the overall performance of the model. Moreover, negative samples are typically treated uniformly, without considering their difficulty levels, and the alignment of positive samples is insufficient, which leads to challenges in aligning difficult sample pairs. To address these issues, we propose Adaptive Hard Negative Perturbation Learning (AHNPL). AHNPL translates text-based hard negatives into the visual domain to generate semantically disturbed image-based negatives for training the model, thereby enhancing its overall performance. AHNPL also introduces a contrastive learning approach using a multimodal hard negative loss to improve the model's discrimination of hard negatives within each modality and a dynamic margin loss that adjusts the contrastive margin according to sample difficulty to enhance the distinction of challenging sample pairs. Experiments on three public datasets demonstrate that our method effectively boosts VLMs' performance on complex CR tasks. The source code is available at https://github.com/nynu-BDAI/AHNPL.
Research on Graph Structure Learning (GSL) provides key insights for graph-based clustering, yet current methods like Graph Neural Networks (GNNs), Graph Attention Networks (GATs), and contrastive learning often rely heavily on the original graph structure. Their performance deteriorates when the original graph's adjacency matrix is too sparse or contains noisy edges unrelated to clustering. Moreover, these methods depend on learning node embeddings and using traditional techniques like k-means to form clusters, which may not fully capture the underlying graph structure between nodes. To address these limitations, this paper introduces DeSE, a novel unsupervised graph clustering framework incorporating Deep Structural Entropy. It enhances the original graph with quantified structural information and deep neural networks to form clusters. Specifically, we first propose a method for calculating structural entropy with soft assignment, which quantifies structure in a differentiable form. Next, we design a Structural Learning layer (SLL) to generate an attributed graph from the original feature data, serving as a target to enhance and optimize the original structural graph, thereby mitigating the issue of sparse connections between graph nodes. Finally, our clustering assignment method (ASS), based on GNNs, learns node embeddings and a soft assignment matrix to cluster on the enhanced graph. The ASS layer can be stacked to meet downstream task requirements, minimizing structural entropy for stable clustering and maximizing node consistency with edge-based cross-entropy loss. Extensive comparative experiments are conducted on four benchmark datasets against eight representative unsupervised graph clustering baselines, demonstrating the superiority of the DeSE in both effectiveness and interpretability.
The open-world assumption in model development suggests that a model might lack sufficient information to adequately handle data that is entirely distinct or out of distribution (OOD). While deep learning methods have shown promising results in handling OOD data through generalization techniques, they often require specialized hardware that may not be accessible to all users. We present TCL, a lightweight yet effective solution that operates efficiently on standard CPU hardware. Our approach adapts contrastive learning principles specifically for tabular data structures, incorporating full matrix augmentation and simplified loss calculation. Through comprehensive experiments across 10 diverse datasets, we demonstrate that TCL outperforms existing models, including FT-Transformer and ResNet, particularly in classification tasks, while maintaining competitive performance in regression problems. TCL achieves these results with significantly reduced computational requirements, making it accessible to users with limited hardware capabilities. This study also provides practical guidance for detecting and evaluating OOD data through straightforward experiments and visualizations. Our findings show that TCL offers a promising balance between performance and efficiency in handling OOD prediction tasks, which is particularly beneficial for general machine learning practitioners working with computational constraints.
Graphs serve as versatile data structures in numerous real-world domains-including social networks, molecular biology, and knowledge graphs-by capturing intricate relational information among entities. Among graph-based learning techniques, Graph Contrastive Learning (GCL) has gained significant attention for its ability to derive robust, self-supervised graph representations through the contrasting of positive and negative sample pairs. However, a critical challenge lies in ensuring high-quality positive pairs so that the intrinsic semantic and structural properties of the original graph are preserved rather than distorted. To address this issue, we propose SRGCL (Self-Reinforced Graph Contrastive Learning), a novel framework that leverages the model's own encoder to dynamically evaluate and select high-quality positive pairs. We designed a unified positive pair generator employing multiple augmentation strategies, and a selector guided by the manifold hypothesis to maintain the underlying geometry of the latent space. By adopting a probabilistic mechanism for selecting positive pairs, SRGCL iteratively refines its assessment of pair quality as the encoder's representational power improves. Extensive experiments on diverse graph-level classification tasks demonstrate that SRGCL, as a plug-in module, consistently outperforms state-of-the-art GCL methods, underscoring its adaptability and efficacy across various domains.
Citation classification, which identifies the intention behind academic citations, is pivotal for scholarly analysis. Previous works suggest fine-tuning pretrained language models (PLMs) on citation classification datasets, reaping the reward of the linguistic knowledge they gained during pretraining. However, directly fine-tuning for citation classification is challenging due to labeled data scarcity, contextual noise, and spurious keyphrase correlations. In this paper, we present a novel framework, Citss, that adapts the PLMs to overcome these challenges. Citss introduces self-supervised contrastive learning to alleviate data scarcity, and is equipped with two specialized strategies to obtain the contrastive pairs: sentence-level cropping, which enhances focus on target citations within long contexts, and keyphrase perturbation, which mitigates reliance on specific keyphrases. Compared with previous works that are only designed for encoder-based PLMs, Citss is carefully developed to be compatible with both encoder-based PLMs and decoder-based LLMs, to embrace the benefits of enlarged pretraining. Experiments with three benchmark datasets with both encoder-based PLMs and decoder-based LLMs demonstrate our superiority compared to the previous state of the art. Our code is available at: github.com/LITONG99/Citss