Irony is a powerful figurative language (FL) on social media that can potentially mislead various NLP tasks, such as recommendation systems, misinformation checks, and sentiment analysis. Understanding the implicit meaning of this kind of subtle language is essential to mitigate irony's negative impact on NLP tasks. However, building models to understand irony presents a unique set of challenges, because irony is a complex form of language that often relies on context, tone, and subtle cues to convey meaning that is opposite or different from the literal interpretation. Large language models, such as ChatGPT, are increasingly able to capture implicit and contextual information. In this study, we investigate the generalization, reasoning and understanding ability of ChatGPT on irony detection across six different genre irony detection datasets. Our findings suggest that ChatGPT appears to show an enhanced language understanding and reasoning ability. But it needs to be very careful in prompt engineering design. Thus, we propose a prompt engineering design framework IDADP to achieve higher irony detection accuracy, improved understanding of irony, and more effective explanations compared to other state-of-the-art ChatGPT zero-shot approaches. And ascertain via experiments that the practice generated under the framework is likely to be the promised solution to resolve the generalization issues of LLMs.
The success of Large Language Models (LLMs) in various domains has led researchers to apply them to graph-related problems by converting graph data into natural language text. However, unlike graph data, natural language inherently has sequential order. We observe a counter-intuitive fact that when the order of nodes or edges in the natural language description of a graph is shuffled, despite describing the same graph, model performance fluctuates between high performance and random guessing. Additionally, due to LLMs' limited input context length, current methods typically randomly sample neighbors of target nodes as representatives of their neighborhood, which may not always be effective for accurate reasoning. To address these gaps, we introduce GraphSOS (Graph Sampling and Order Selection). This novel model framework features an Order Selector Module to ensure proper serialization order of the graph and a Subgraph Sampling Module to sample subgraphs with better structure for better reasoning. Furthermore, we propose Graph CoT obtained through distillation, and enhance LLM's reasoning and zero-shot learning capabilities for graph tasks through instruction tuning. Experiments on multiple datasets for node classification and graph question-answering demonstrate that GraphSOS improves LLMs' performance and generalization ability on graph tasks.
Artificial intelligence (AI) shows great potential in assisting radiologists to improve the efficiency and accuracy of medical image interpretation and diagnosis. However, a versatile AI model requires large-scale data and comprehensive annotations, which are often impractical in medical settings. Recent studies leverage radiology reports as a naturally high-quality supervision for medical images, using contrastive language-image pre-training (CLIP) to develop language-informed models for radiological image interpretation. Nonetheless, these approaches typically contrast entire images with reports, neglecting the local associations between imaging regions and report sentences, which may undermine model performance and interoperability. In this paper, we propose a fine-grained vision-language model (fVLM) for anatomy-level CT image interpretation. Specifically, we explicitly match anatomical regions of CT images with corresponding descriptions in radiology reports and perform contrastive pre-training for each anatomy individually. Fine-grained alignment, however, faces considerable false-negative challenges, mainly from the abundance of anatomy-level healthy samples and similarly diseased abnormalities. To tackle this issue, we propose identifying false negatives of both normal and abnormal samples and calibrating contrastive learning from patient-level to disease-aware pairing. We curated the largest CT dataset to date, comprising imaging and report data from 69,086 patients, and conducted a comprehensive evaluation of 54 major and important disease diagnosis tasks across 15 main anatomies. Experimental results demonstrate the substantial potential of fVLM in versatile medical image interpretation. In the zero-shot classification task, we achieved an average AUC of 81.3% on 54 diagnosis tasks, surpassing CLIP and supervised methods by 12.9% and 8.0%, respectively.
Compositional Zero-Shot Learning (CZSL) aims to identify unseen state-object compositions by leveraging knowledge learned from seen compositions. Existing approaches often independently predict states and objects, overlooking their relationships. In this paper, we propose a novel framework, learning primitive relations (LPR), designed to probabilistically capture the relationships between states and objects. By employing the cross-attention mechanism, LPR considers the dependencies between states and objects, enabling the model to infer the likelihood of unseen compositions. Experimental results demonstrate that LPR outperforms state-of-the-art methods on all three CZSL benchmark datasets in both closed-world and open-world settings. Through qualitative analysis, we show that LPR leverages state-object relationships for unseen composition prediction.
Multi-modal models require aligned, shared embedding spaces. However, common CLIP-based approaches need large amounts of samples and do not natively support 3D or tabular data, both of which are crucial in the medical domain. To address these issues, we revisit CLIP-style alignment by training a domain-specific 3D foundation model as an image encoder and demonstrate that modality alignment is feasible with only 62 MRI scans. Our approach is enabled by a simple embedding accumulation strategy required for training in 3D, which scales the amount of negative pairs across batches in order to stabilize training. We perform a thorough evaluation of various design choices, including the choice of backbone and loss functions, and evaluate the proposed methodology on zero-shot classification and image-retrieval tasks. While zero-shot image-retrieval remains challenging, zero-shot classification results demonstrate that the proposed approach can meaningfully align the representations of 3D MRI with tabular data.
The updated recommendations on diagnostic procedures and treatment pathways for a medical condition are documented as graphical flows in Clinical Practice Guidelines (CPGs). For effective use of the CPGs in helping medical professionals in the treatment decision process, it is necessary to fully capture the guideline knowledge, particularly the contexts and their relationships in the graph. While several existing works have utilized these guidelines to create rule bases for Clinical Decision Support Systems, limited work has been done toward directly capturing the full medical knowledge contained in CPGs. This work proposes an approach to create a contextually enriched, faithful digital representation of National Comprehensive Cancer Network (NCCN) Cancer CPGs in the form of graphs using automated extraction and node & relationship classification. We also implement semantic enrichment of the model by using Large Language Models (LLMs) for node classification, achieving an accuracy of 80.86% and 88.47% with zero-shot learning and few-shot learning, respectively. Additionally, we introduce a methodology for answering natural language questions with constraints to guideline text by leveraging LLMs to extract the relevant subgraph from the guideline knowledge base. By generating natural language answers based on subgraph paths and semantic information, we mitigate the risk of incorrect answers and hallucination associated with LLMs, ensuring factual accuracy in medical domain Question Answering.
Compositional Zero-Shot Learning (CZSL) aims to recognize novel compositions of attributes and objects by leveraging knowledge learned from seen compositions. Recent approaches have explored the use of Vision-Language Models (VLMs) to align textual and visual modalities. These methods typically employ prompt engineering, parameter-tuning, and modality fusion to generate rich textual prototypes that serve as class prototypes for CZSL. However, the modality gap results in textual prototypes being unable to fully capture the optimal representations of all class prototypes, particularly those with fine-grained features, which can be directly obtained from the visual modality. In this paper, we propose a novel Dual-Modal Prototype Joint Learning framework for the CZSL task. Our approach, based on VLMs, introduces prototypes in both the textual and visual modalities. The textual prototype is optimized to capture broad conceptual information, aiding the model's generalization across unseen compositions. Meanwhile, the visual prototype is used to mitigate the classification errors caused by the modality gap and capture fine-grained details to distinguish images with similar appearances. To effectively optimize these prototypes, we design specialized decomposition modules and a joint learning strategy that enrich the features from both modalities. These prototypes not only capture key category information during training but also serve as crucial reference targets during inference. Experimental results demonstrate that our approach achieves state-of-the-art performance in the closed-world setting and competitive performance in the open-world setting across three publicly available CZSL benchmarks. These findings validate the effectiveness of our method in advancing compositional generalization.
Visual Language Models such as CLIP excel in image recognition due to extensive image-text pre-training. However, applying the CLIP inference in zero-shot classification, particularly for medical image diagnosis, faces challenges due to: 1) the inadequacy of representing image classes solely with single category names; 2) the modal gap between the visual and text spaces generated by CLIP encoders. Despite attempts to enrich disease descriptions with large language models, the lack of class-specific knowledge often leads to poor performance. In addition, empirical evidence suggests that existing proxy learning methods for zero-shot image classification on natural image datasets exhibit instability when applied to medical datasets. To tackle these challenges, we introduce the Knowledge Proxy Learning (KPL) to mine knowledge from CLIP. KPL is designed to leverage CLIP's multimodal understandings for medical image classification through Text Proxy Optimization and Multimodal Proxy Learning. Specifically, KPL retrieves image-relevant knowledge descriptions from the constructed knowledge-enhanced base to enrich semantic text proxies. It then harnesses input images and these descriptions, encoded via CLIP, to stably generate multimodal proxies that boost the zero-shot classification performance. Extensive experiments conducted on both medical and natural image datasets demonstrate that KPL enables effective zero-shot image classification, outperforming all baselines. These findings highlight the great potential in this paradigm of mining knowledge from CLIP for medical image classification and broader areas.
Conditional dependency present one of the trickiest problems in Compositional Zero-Shot Learning, leading to significant property variations of the same state (object) across different objects (states). To address this problem, existing approaches often adopt either all-to-one or one-to-one representation paradigms. However, these extremes create an imbalance in the seesaw between transferability and discriminability, favoring one at the expense of the other. Comparatively, humans are adept at analogizing and reasoning in a hierarchical clustering manner, intuitively grouping categories with similar properties to form cohesive concepts. Motivated by this, we propose Homogeneous Group Representation Learning (HGRL), a new perspective formulates state (object) representation learning as multiple homogeneous sub-group representation learning. HGRL seeks to achieve a balance between semantic transferability and discriminability by adaptively discovering and aggregating categories with shared properties, learning distributed group centers that retain group-specific discriminative features. Our method integrates three core components designed to simultaneously enhance both the visual and prompt representation capabilities of the model. Extensive experiments on three benchmark datasets validate the effectiveness of our method.
Cyber Threat Intelligence (CTI) is critical for mitigating threats to organizations, governments, and institutions, yet the necessary data are often dispersed across diverse formats. AI-driven solutions for CTI Information Extraction (IE) typically depend on high-quality, annotated data, which are not always available. This paper introduces 0-CTI, a scalable AI-based framework designed for efficient CTI Information Extraction. Leveraging advanced Natural Language Processing (NLP) techniques, particularly Transformer-based architectures, the proposed system processes complete text sequences of CTI reports to extract a cyber ontology of named entities and their relationships. Our contribution is the development of 0-CTI, the first modular framework for CTI Information Extraction that supports both supervised and zero-shot learning. Unlike existing state-of-the-art models that rely heavily on annotated datasets, our system enables fully dataless operation through zero-shot methods for both Entity and Relation Extraction, making it adaptable to various data availability scenarios. Additionally, our supervised Entity Extractor surpasses current state-of-the-art performance in cyber Entity Extraction, highlighting the dual strength of the framework in both low-resource and data-rich environments. By aligning the system's outputs with the Structured Threat Information Expression (STIX) format, a standard for information exchange in the cybersecurity domain, 0-CTI standardizes extracted knowledge, enhancing communication and collaboration in cybersecurity operations.
This paper investigates the robustness of vision-language models against adversarial visual perturbations and introduces a novel ``double visual defense" to enhance this robustness. Unlike previous approaches that resort to lightweight adversarial fine-tuning of a pre-trained CLIP model, we perform large-scale adversarial vision-language pre-training from scratch using web-scale data. We then strengthen the defense by incorporating adversarial visual instruction tuning. The resulting models from each stage, $\Delta$CLIP and $\Delta^2$LLaVA, show substantially enhanced zero-shot robustness and set a new state-of-the-art in adversarial defense for vision-language models. For example, the adversarial robustness of $\Delta$CLIP surpasses that of the previous best models on ImageNet-1k by ~20%. %For example, $\Delta$CLIP surpasses the previous best models on ImageNet-1k by ~20% in terms of adversarial robustness. Similarly, compared to prior art, $\Delta^2$LLaVA brings a ~30% robustness improvement to image captioning task and a ~20% robustness improvement to visual question answering task. Furthermore, our models exhibit stronger zero-shot recognition capability, fewer hallucinations, and superior reasoning performance compared to baselines. Our project page is https://doublevisualdefense.github.io/.
Zero-shot recognition models require extensive training data for generalization. However, in zero-shot 3D classification, collecting 3D data and captions is costly and laborintensive, posing a significant barrier compared to 2D vision. Recent advances in generative models have achieved unprecedented realism in synthetic data production, and recent research shows the potential for using generated data as training data. Here, naturally raising the question: Can synthetic 3D data generated by generative models be used as expanding limited 3D datasets? In response, we present a synthetic 3D dataset expansion method, Textguided Geometric Augmentation (TeGA). TeGA is tailored for language-image-3D pretraining, which achieves SoTA in zero-shot 3D classification, and uses a generative textto-3D model to enhance and extend limited 3D datasets. Specifically, we automatically generate text-guided synthetic 3D data and introduce a consistency filtering strategy to discard noisy samples where semantics and geometric shapes do not match with text. In the experiment to double the original dataset size using TeGA, our approach demonstrates improvements over the baselines, achieving zeroshot performance gains of 3.0% on Objaverse-LVIS, 4.6% on ScanObjectNN, and 8.7% on ModelNet40. These results demonstrate that TeGA effectively bridges the 3D data gap, enabling robust zero-shot 3D classification even with limited real training data and paving the way for zero-shot 3D vision application.
Remote sensing imagery is dense with objects and contextual visual information. There is a recent trend to combine paired satellite images and text captions for pretraining performant encoders for downstream tasks. However, while contrastive image-text methods like CLIP enable vision-language alignment and zero-shot classification ability, vision-only downstream performance tends to degrade compared to image-only pretraining, such as MAE. In this paper, we propose FLAVARS, a pretraining method that combines the best of both contrastive learning and masked modeling, along with geospatial alignment via contrastive location encoding. We find that FLAVARS significantly outperforms a baseline of SkyCLIP for vision-only tasks such as KNN classification and semantic segmentation, +6\% mIOU on SpaceNet1, while retaining the ability to perform zero-shot classification, unlike MAE pretrained methods.
The development of vision-language models (VLMs) is driven by large-scale and diverse multimodal datasets. However, progress toward generalist biomedical VLMs is limited by the lack of annotated, publicly accessible datasets across biology and medicine. Existing efforts are restricted to narrow domains, missing the full diversity of biomedical knowledge encoded in scientific literature. To address this gap, we introduce BIOMEDICA, a scalable, open-source framework to extract, annotate, and serialize the entirety of the PubMed Central Open Access subset into an easy-to-use, publicly accessible dataset. Our framework produces a comprehensive archive with over 24 million unique image-text pairs from over 6 million articles. Metadata and expert-guided annotations are also provided. We demonstrate the utility and accessibility of our resource by releasing BMCA-CLIP, a suite of CLIP-style models continuously pre-trained on the BIOMEDICA dataset via streaming, eliminating the need to download 27 TB of data locally. On average, our models achieve state-of-the-art performance across 40 tasks - spanning pathology, radiology, ophthalmology, dermatology, surgery, molecular biology, parasitology, and cell biology - excelling in zero-shot classification with a 6.56% average improvement (as high as 29.8% and 17.5% in dermatology and ophthalmology, respectively), and stronger image-text retrieval, all while using 10x less compute. To foster reproducibility and collaboration, we release our codebase and dataset for the broader research community.
Compositional Zero-Shot Learning (CZSL) aims to enable models to recognize novel compositions of visual states and objects that were absent during training. Existing methods predominantly focus on learning semantic representations of seen compositions but often fail to disentangle the independent features of states and objects in images, thereby limiting their ability to generalize to unseen compositions. To address this challenge, we propose Duplex, a novel dual-prototype learning method that integrates semantic and visual prototypes through a carefully designed dual-branch architecture, enabling effective representation learning for compositional tasks. Duplex utilizes a Graph Neural Network (GNN) to adaptively update visual prototypes, capturing complex interactions between states and objects. Additionally, it leverages the strong visual-semantic alignment of pre-trained Vision-Language Models (VLMs) and employs a multi-path architecture combined with prompt engineering to align image and text representations, ensuring robust generalization. Extensive experiments on three benchmark datasets demonstrate that Duplex outperforms state-of-the-art methods in both closed-world and open-world settings.
Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face significant challenges in medical question answering, particularly in understanding domain-specific terminologies and performing complex reasoning. These limitations undermine their effectiveness in critical medical applications. To address these issues, we propose a novel approach incorporating similar case generation within a multi-agent medical question-answering (MedQA) system. Specifically, we leverage the Llama3.1:70B model, a state-of-the-art LLM, in a multi-agent architecture to enhance performance on the MedQA dataset using zero-shot learning. Our method capitalizes on the model's inherent medical knowledge and reasoning capabilities, eliminating the need for additional training data. Experimental results show substantial performance gains over existing benchmark models, with improvements of 7% in both accuracy and F1-score across various medical QA tasks. Furthermore, we examine the model's interpretability and reliability in addressing complex medical queries. This research not only offers a robust solution for medical question answering but also establishes a foundation for broader applications of LLMs in the medical domain.
Transductive zero-shot learning with vision-language models leverages image-image similarities within the dataset to achieve better classification accuracy compared to the inductive setting. However, there is little work that explores the structure of the language space in this context. We propose GTA-CLIP, a novel technique that incorporates supervision from language models for joint transduction in language and vision spaces. Our approach is iterative and consists of three steps: (i) incrementally exploring the attribute space by querying language models, (ii) an attribute-augmented transductive inference procedure, and (iii) fine-tuning the language and vision encoders based on inferred labels within the dataset. Through experiments with CLIP encoders, we demonstrate that GTA-CLIP, yields an average performance improvement of 8.6% and 3.7% across 12 datasets and 3 encoders, over CLIP and transductive CLIP respectively in the zero-shot setting. We also observe similar improvements in a few-shot setting. We present ablation studies that demonstrate the value of each step and visualize how the vision and language spaces evolve over iterations driven by the transductive learning.
Named entity recognition is an important task when constructing knowledge bases from unstructured data sources. Whereas entity detection methods mostly rely on extensive training data, Large Language Models (LLMs) have paved the way towards approaches that rely on zero-shot learning (ZSL) or few-shot learning (FSL) by taking advantage of the capabilities LLMs acquired during pretraining. Specifically, in very specialized scenarios where large-scale training data is not available, ZSL / FSL opens new opportunities. This paper follows this recent trend and investigates the potential of leveraging Large Language Models (LLMs) in such scenarios to automatically detect datasets and software within textual content from GitHub repositories. While existing methods focused solely on named entities, this study aims to broaden the scope by incorporating resources such as repositories and online hubs where entities are also represented by URLs. The study explores different FSL prompt learning approaches to enhance the LLMs' ability to identify dataset and software mentions within repository texts. Through analyses of LLM effectiveness and learning strategies, this paper offers insights into the potential of advanced language models for automated entity detection.
Multi-modal generative AI systems, such as those combining vision and language, rely on contrastive pre-training to learn representations across different modalities. While their practical benefits are widely acknowledged, a rigorous theoretical understanding of the contrastive pre-training framework remains limited. This paper develops a theoretical framework to explain the success of contrastive pre-training in downstream tasks, such as zero-shot classification, conditional diffusion models, and vision-language models. We introduce the concept of approximate sufficient statistics, a generalization of the classical sufficient statistics, and show that near-minimizers of the contrastive pre-training loss are approximately sufficient, making them adaptable to diverse downstream tasks. We further propose the Joint Generative Hierarchical Model for the joint distribution of images and text, showing that transformers can efficiently approximate relevant functions within this model via belief propagation. Building on this framework, we derive sample complexity guarantees for multi-modal learning based on contrastive pre-trained representations. Numerical simulations validate these theoretical findings, demonstrating the strong generalization performance of contrastively pre-trained transformers in various multi-modal tasks.
3D medical images such as Computed tomography (CT) are widely used in clinical practice, offering a great potential for automatic diagnosis. Supervised learning-based approaches have achieved significant progress but rely heavily on extensive manual annotations, limited by the availability of training data and the diversity of abnormality types. Vision-language alignment (VLA) offers a promising alternative by enabling zero-shot learning without additional annotations. However, we empirically discover that the visual and textural embeddings after alignment endeavors from existing VLA methods form two well-separated clusters, presenting a wide gap to be bridged. To bridge this gap, we propose a Bridged Semantic Alignment (BrgSA) framework. First, we utilize a large language model to perform semantic summarization of reports, extracting high-level semantic information. Second, we design a Cross-Modal Knowledge Interaction (CMKI) module that leverages a cross-modal knowledge bank as a semantic bridge, facilitating interaction between the two modalities, narrowing the gap, and improving their alignment. To comprehensively evaluate our method, we construct a benchmark dataset that includes 15 underrepresented abnormalities as well as utilize two existing benchmark datasets. Experimental results demonstrate that BrgSA achieves state-of-the-art performances on both public benchmark datasets and our custom-labeled dataset, with significant improvements in zero-shot diagnosis of underrepresented abnormalities.