This study offers an in-depth analysis of smart wheelchair (SW) systems, charting their progression from early developments to future innovations. It delves into various Brain-Computer Interface (BCI) systems, including mu rhythm, event-related potential, and steady-state visual evoked potential. The paper addresses challenges in signal categorization, proposing the sparse Bayesian extreme learning machine as an innovative solution. Additionally, it explores the integration of emotional states in BCI systems, the application of alternative control methods such as EMG-based systems, and the deployment of intelligent adaptive interfaces utilizing recurrent quantum neural networks. The study also covers advancements in autonomous navigation, assistance, and mapping, emphasizing their importance in SW systems. The human aspect of SW interaction receives considerable attention, specifically in terms of privacy, physiological factors, and the refinement of control mechanisms. The paper acknowledges the commercial challenges faced, like the limitations of indoor usage and the necessity for user training. For future applications, the research explores the potential of autonomous systems adept at adapting to changing environments and user needs. This exploration includes reinforcement learning and various control methods, such as eye and voice control, to improve adaptability and interaction. The potential integration with smart home technologies, including advanced features such as robotic arms, is also considered, aiming to further enhance user accessibility and independence. Ultimately, this study seeks to provide a thorough overview of SW systems, presenting extensive research to detail their historical evolution, current state, and future prospects.
Recent advances in brain-computer interface (BCI) technology, particularly based on generative adversarial networks (GAN), have shown great promise for improving decoding performance for BCI. Within the realm of Brain-Computer Interfaces (BCI), GANs find application in addressing many areas. They serve as a valuable tool for data augmentation, which can solve the challenge of limited data availability, and synthesis, effectively expanding the dataset and creating novel data formats, thus enhancing the robustness and adaptability of BCI systems. Research in speech-related paradigms has significantly expanded, with a critical impact on the advancement of assistive technologies and communication support for individuals with speech impairments. In this study, GANs were investigated, particularly for the BCI field, and applied to generate text from EEG signals. The GANs could generalize all subjects and decode unseen words, indicating its ability to capture underlying speech patterns consistent across different individuals. The method has practical applications in neural signal-based speech recognition systems and communication aids for individuals with speech difficulties.
Brain-computer interfaces (BCIs) offer a way to interact with computers without relying on physical movements. Non-invasive electroencephalography (EEG)-based visual BCIs, known for efficient speed and calibration ease, face limitations in continuous tasks due to discrete stimulus design and decoding methods. To achieve continuous control, we implemented a novel spatial encoding stimulus paradigm and devised a corresponding projection method to enable continuous modulation of decoded velocity. Subsequently, we conducted experiments involving 17 participants and achieved Fitt's ITR of 0.55 bps for the fixed tracking task and 0.37 bps for the random tracking task. The proposed BCI with a high Fitt's ITR was then integrated into two applications, including painting and gaming. In conclusion, this study proposed a visual BCI-based control method to go beyond discrete commands, allowing natural continuous control based on neural activity.
Deep learning has shown promise in decoding brain signals, such as electroencephalogram (EEG), in the field of brain-computer interfaces (BCIs). However, the non-stationary characteristics of EEG signals pose challenges for training neural networks to acquire appropriate knowledge. Inconsistent EEG signals resulting from these non-stationary characteristics can lead to poor performance. Therefore, it is crucial to investigate and address sample inconsistency to ensure robust performance in spontaneous BCIs. In this study, we introduce the concept of sample dominance as a measure of EEG signal inconsistency and propose a method to modulate its effect on network training. We present a two-stage dominance score estimation technique that compensates for performance degradation caused by sample inconsistencies. Our proposed method utilizes non-parametric estimation to infer sample inconsistency and assigns each sample a dominance score. This score is then aggregated with the loss function during training to modulate the impact of sample inconsistency. Furthermore, we design a curriculum learning approach that gradually increases the influence of inconsistent signals during training to improve overall performance. We evaluate our proposed method using public spontaneous BCI dataset. The experimental results confirm that our findings highlight the importance of addressing sample dominance for achieving robust performance in spontaneous BCIs.
Motor imagery EEG classification plays a crucial role in non-invasive Brain-Computer Interface (BCI) research. However, the classification is affected by the non-stationarity and individual variations of EEG signals. Simply pooling EEG data with different statistical distributions to train a classification model can severely degrade the generalization performance. To address this issue, the existing methods primarily focus on domain adaptation, which requires access to the target data during training. This is unrealistic in many EEG application scenarios. In this paper, we propose a novel multi-source domain generalization framework called EEG-DG, which leverages multiple source domains with different statistical distributions to build generalizable models on unseen target EEG data. We optimize both the marginal and conditional distributions to ensure the stability of the joint distribution across source domains and extend it to a multi-source domain generalization framework to achieve domain-invariant feature representation, thereby alleviating calibration efforts. Systematic experiments on a simulative dataset and BCI competition datasets IV-2a and IV-2b demonstrate the superiority of our proposed EEG-DG over state-of-the-art methods. Specifically, EEG-DG achieves an average classification accuracy/kappa value of 81.79%/0.7572 and 87.12%/0.7424 on datasets IV-2a and IV-2b, respectively, which even outperforms some domain adaptation methods. Our code is available at https://github.com/XC-ZhongHIT/EEG-DG for free download and evaluation.
To handle the scarcity and heterogeneity of electroencephalography (EEG) data for Brain-Computer Interface (BCI) tasks, and to harness the power of large publicly available data sets, we propose Neuro-GPT, a foundation model consisting of an EEG encoder and a GPT model. The foundation model is pre-trained on a large-scale data set using a self-supervised task that learns how to reconstruct masked EEG segments. We then fine-tune the model on a Motor Imagery Classification task to validate its performance in a low-data regime (9 subjects). Our experiments demonstrate that applying a foundation model can significantly improve classification performance compared to a model trained from scratch, which provides evidence for the generalizability of the foundation model and its ability to address challenges of data scarcity and heterogeneity in EEG. The code is publicly available at github.com/wenhui0206/NeuroGPT.
As a typical self-paced brain-computer interface (BCI) system, the motor imagery (MI) BCI has been widely applied in fields such as robot control, stroke rehabilitation, and assistance for patients with stroke or spinal cord injury. Many studies have focused on the traditional spatial filters obtained through the common spatial pattern (CSP) method. However, the CSP method can only obtain fixed spatial filters for specific input signals. Besides, CSP method only focuses on the variance difference of two types of electroencephalogram (EEG) signals, so the decoding ability of EEG signals is limited. To obtain more effective spatial filters for better extraction of spatial features that can improve classification to MI-EEG, this paper proposes an adaptive spatial filter solving method based on particle swarm optimization algorithm (PSO). A training and testing framework based on filter bank and spatial filters (FBCSP-ASP) is designed for MI EEG signal classification. Comparative experiments are conducted on two public datasets (2a and 2b) from BCI competition IV, which show the outstanding average recognition accuracy of FBCSP-ASP. The proposed method has achieved significant performance improvement on MI-BCI. The classification accuracy of the proposed method has reached 74.61% and 81.19% on datasets 2a and 2b, respectively. Compared with the baseline algorithm (FBCSP), the proposed algorithm improves 11.44% and 7.11% on two datasets respectively. Furthermore, the analysis based on mutual information, t-SNE and Shapley values further proves that ASP features have excellent decoding ability for MI-EEG signals, and explains the improvement of classification performance by the introduction of ASP features.
The bottom two layers of a neuromorphic architecture are designed and shown to be capable of online clustering and supervised classification. An active spiking dendrite model is used, and a single dendritic segment performs essentially the same function as a classic integrate-and-fire point neuron. A single dendrite is then composed of multiple segments and is capable of online clustering. Although this work focuses primarily on dendrite functionality, a multi-point neuron can be formed by combining multiple dendrites. To demonstrate its clustering capability, a dendrite is applied to spike sorting, an important component of brain-computer interface applications. Supervised online classification is implemented as a network composed of multiple dendrites and a simple voting mechanism. The dendrites operate independently and in parallel. The network learns in an online fashion and can adapt to macro-level changes in the input stream. Achieving brain-like capabilities, efficiencies, and adaptability will require a significantly different approach than conventional deep networks that learn via compute-intensive back propagation. The model described herein may serve as the foundation for such an approach.
The objective of this study is to investigate the application of various channel attention mechanisms within the domain of brain-computer interface (BCI) for motor imagery decoding. Channel attention mechanisms can be seen as a powerful evolution of spatial filters traditionally used for motor imagery decoding. This study systematically compares such mechanisms by integrating them into a lightweight architecture framework to evaluate their impact. We carefully construct a straightforward and lightweight baseline architecture designed to seamlessly integrate different channel attention mechanisms. This approach is contrary to previous works which only investigate one attention mechanism and usually build a very complex, sometimes nested architecture. Our framework allows us to evaluate and compare the impact of different attention mechanisms under the same circumstances. The easy integration of different channel attention mechanisms as well as the low computational complexity enables us to conduct a wide range of experiments on four datasets to thoroughly assess the effectiveness of the baseline model and the attention mechanisms. Our experiments demonstrate the strength and generalizability of our architecture framework as well as how channel attention mechanisms can improve the performance while maintaining the small memory footprint and low computational complexity of our baseline architecture. Our architecture emphasizes simplicity, offering easy integration of channel attention mechanisms, while maintaining a high degree of generalizability across datasets, making it a versatile and efficient solution for EEG motor imagery decoding within brain-computer interfaces.
Deep neural networks (DNN) have become increasingly utilized in brain-computer interface (BCI) technologies with the outset goal of classifying human physiological signals in computer-readable format. While our present understanding of DNN usage for BCI is promising, we have little experience in deciphering neural events from dynamic freely-mobile situations. Using an improved version of EEGNet, our goal was to classify cognitive events from electroencephalography (EEG) signals while subjects simultaneously walked on a treadmill, sometimes while carrying a rucksack equivalent to 40% of their body weight. Walking subjects simultaneously performed a visual oddball target detection task, eliciting the P300 event-related potential (ERP), which then served as the DNN classification target. We found the base EEGNet to reach classification levels well above chance, with similar performance to previously reported P300 results. We found performance to be robust to noise, with classification similar for walking and loaded walking, with respect to standard seated condition with minimal movement. With additional architectural search and tuning to the EEGNet model (termed Cog-Neuro, herein; CN-EEGNet), we reached classification accuracy of greater than 95%, similar to previously reported state of the art levels in seated P300 tasks. To our knowledge, these results are the first documented implementation of a DNN for the classification of cognitive neural state during dual-task walking. The classification of one's ongoing cognitive state during a demanding physical task establishes the utility for BCI in complex environments.
This article discusses practical and theoretical aspects of real-time brain computer interface control methods based on Bayesian statistics. We investigate and improve the performance of automatic control and feedback algorithms of a reactive brain computer interface based on a visual oddball paradigm for faster statistical convergence. We introduce transfer learning using Gaussian mixture models, enabling a ready-to-use setup.
Phase synchrony information plays a crucial role in analyzing functional brain connectivity and identifying brain activities. A widely adopted feature extraction pipeline, composed of preprocessing, selection of EEG acquisition channels, and phase locking value (PLV) calculation, has achieved success in motor imagery classification (MI). However, this pipeline is manual and reliant on expert knowledge, limiting its convenience and adaptability to different application scenarios. Moreover, most studies have employed mediocre data-independent spatial filters to suppress noise, impeding the exploration of more significant phase synchronization phenomena. To address the issues, we propose the concept of phase synchrony component self-organization, which enables the adaptive learning of data-dependent spatial filters for automating both the preprocessing and channel selection procedures. Based on this concept, the first deep learning end-to-end network is developed, which directly extracts phase synchrony-based features from raw EEG signals and perform classification. The network learns optimal filters during training, which are obtained when the network achieves peak classification results. Extensive experiments have demonstrated that our network outperforms state-of-the-art methods. Remarkably, through the learned optimal filters, significant phase synchronization phenomena can be observed. Specifically, by calculating the PLV between a pair of signals extracted from each sample using two of the learned spatial filters, we have obtained an average PLV exceeding 0.87 across all tongue MI samples. This high PLV indicates a groundbreaking discovery in the synchrony pattern of tongue MI.
Brain-computer interfaces (BCI) are presented as a solution for people with global paralysis, also known as locked-in syndrome (LIS). The targeted population includes the most severe patients, with no residual eye movements, who cannot use any communication device (Complete LIS). However, BCI reliability is low precisely in these cases, technical pitfalls being considered responsible so far. Here, we propose to consider also that global paralysis could have an impact on cognitive functions that are crucial for being able to control a BCI. We review a bundle of arguments about the role of motor structures in cognition. Especially, we uncover that these patients without oculomotor activity often have injuries in more 'cognitive' structures such as the frontal eye field or the midbrain, exposing them to cognitive deficits further than canonical LIS population. We develop a hypothesis about the putative role of the motor system in (covert) attention, a capacity which is a prerequisite for most BCI paradigms and which should therefore be both better assessed in patients and considered.
Brain-Computer Interface (BCI) systems allow users to perform actions by translating their brain activity into commands. Such systems usually need a training phase, consisting in training a classification algorithm to discriminate between mental states using specific features from the recorded signals. This phase of feature selection and training is crucial for BCI performance and presents specific constraints to be met in a clinical context, such as post-stroke rehabilitation. In this paper, we present HappyFeat, a software making Motor Imagery (MI) based BCI experiments easier, by gathering all necessary manipulations and analysis in a single convenient GUI and via automation of experiment or analysis parameters. The resulting workflow allows for effortlessly selecting the best features, helping to achieve good BCI performance in time-constrained environments. Alternative features based on Functional Connectivity can be used and compared or combined with Power Spectral Density, allowing a network-oriented approach. We then give details of HappyFeat's main mechanisms, and a review of its performances in typical use cases. We also show that it can be used as an efficient tool for comparing different metrics extracted from the signals, to train the classification algorithm. To this end, we show a comparison between the commonly-used Power Spectral Density and network metrics based on Functional Connectivity. HappyFeat is available as an open-source project which can be freely downloaded on GitHub.
While significant advancements in artificial intelligence (AI) have catalyzed progress across various domains, its full potential in understanding visual perception remains underexplored. We propose an artificial neural network dubbed VISION, an acronym for "Visual Interface System for Imaging Output of Neural activity," to mimic the human brain and show how it can foster neuroscientific inquiries. Using visual and contextual inputs, this multimodal model predicts the brain's functional magnetic resonance imaging (fMRI) scan response to natural images. VISION successfully predicts human hemodynamic responses as fMRI voxel values to visual inputs with an accuracy exceeding state-of-the-art performance by 45%. We further probe the trained networks to reveal representational biases in different visual areas, generate experimentally testable hypotheses, and formulate an interpretable metric to associate these hypotheses with cortical functions. With both a model and evaluation metric, the cost and time burdens associated with designing and implementing functional analysis on the visual cortex could be reduced. Our work suggests that the evolution of computational models may shed light on our fundamental understanding of the visual cortex and provide a viable approach toward reliable brain-machine interfaces.
Measuring the bioelectric signals is one of the key functions in wearable healthcare devices and implantable medical devices. The use of wearable healthcare devices has made continuous and immediate monitoring of personal health status possible. Implantable medical devices have played an important role throughout the fields of neuroscience, brain-machine (or brain-computer) interface, and rehabilitation technology. Over the last five decades, the bioelectric signals have been observed through a variety of biopotential recording front-ends, along with advances in semiconductor technology scaling and circuit techniques. Also, for reliable and continuous signal acquisition, the front-end architectures have evolved while maintaining low power and low noise performance. In this article, the architecture history of the biopotential recording front-ends developed since the 1970s is surveyed, and overall key circuit techniques are discussed. Depending on the bioelectric signals being measured, appropriate front-end architecture needs to be chosen, and the characteristics and challenges of each architecture are also covered in this article.
There is a correlation between adjacent channels of electroencephalogram (EEG), and how to represent this correlation is an issue that is currently being explored. In addition, due to inter-individual differences in EEG signals, this discrepancy results in new subjects need spend a amount of calibration time for EEG-based motor imagery brain-computer interface. In order to solve the above problems, we propose a Dynamic Domain Adaptation Based Deep Learning Network (DADL-Net). First, the EEG data is mapped to the three-dimensional geometric space and its temporal-spatial features are learned through the 3D convolution module, and then the spatial-channel attention mechanism is used to strengthen the features, and the final convolution module can further learn the spatial-temporal information of the features. Finally, to account for inter-subject and cross-sessions differences, we employ a dynamic domain-adaptive strategy, the distance between features is reduced by introducing a Maximum Mean Discrepancy loss function, and the classification layer is fine-tuned by using part of the target domain data. We verify the performance of the proposed method on BCI competition IV 2a and OpenBMI datasets. Under the intra-subject experiment, the accuracy rates of 70.42% and 73.91% were achieved on the OpenBMI and BCIC IV 2a datasets.
Adaptive interfaces can help users perform sequential decision-making tasks like robotic teleoperation given noisy, high-dimensional command signals (e.g., from a brain-computer interface). Recent advances in human-in-the-loop machine learning enable such systems to improve by interacting with users, but tend to be limited by the amount of data that they can collect from individual users in practice. In this paper, we propose a reinforcement learning algorithm to address this by training an interface to map raw command signals to actions using a combination of offline pre-training and online fine-tuning. To address the challenges posed by noisy command signals and sparse rewards, we develop a novel method for representing and inferring the user's long-term intent for a given trajectory. We primarily evaluate our method's ability to assist users who can only communicate through noisy, high-dimensional input channels through a user study in which 12 participants performed a simulated navigation task by using their eye gaze to modulate a 128-dimensional command signal from their webcam. The results show that our method enables successful goal navigation more often than a baseline directional interface, by learning to denoise user commands signals and provide shared autonomy assistance. We further evaluate on a simulated Sawyer pushing task with eye gaze control, and the Lunar Lander game with simulated user commands, and find that our method improves over baseline interfaces in these domains as well. Extensive ablation experiments with simulated user commands empirically motivate each component of our method.
Insufficient data is a long-standing challenge for Brain-Computer Interface (BCI) to build a high-performance deep learning model. Though numerous research groups and institutes collect a multitude of EEG datasets for the same BCI task, sharing EEG data from multiple sites is still challenging due to the heterogeneity of devices. The significance of this challenge cannot be overstated, given the critical role of data diversity in fostering model robustness. However, existing works rarely discuss this issue, predominantly centering their attention on model training within a single dataset, often in the context of inter-subject or inter-session settings. In this work, we propose a hierarchical personalized Federated Learning EEG decoding (FLEEG) framework to surmount this challenge. This innovative framework heralds a new learning paradigm for BCI, enabling datasets with disparate data formats to collaborate in the model training process. Each client is assigned a specific dataset and trains a hierarchical personalized model to manage diverse data formats and facilitate information exchange. Meanwhile, the server coordinates the training procedure to harness knowledge gleaned from all datasets, thus elevating overall performance. The framework has been evaluated in Motor Imagery (MI) classification with nine EEG datasets collected by different devices but implementing the same MI task. Results demonstrate that the proposed frame can boost classification performance up to 16.7% by enabling knowledge sharing between multiple datasets, especially for smaller datasets. Visualization results also indicate that the proposed framework can empower the local models to put a stable focus on task-related areas, yielding better performance. To the best of our knowledge, this is the first end-to-end solution to address this important challenge.
Objective: BCI (Brain-Computer Interface) technology operates in three modes: online, offline, and pseudo-online. In the online mode, real-time EEG data is constantly analyzed. In offline mode, the signal is acquired and processed afterwards. The pseudo-online mode processes collected data as if they were received in real-time. The main difference is that the offline mode often analyzes the whole data, while the online and pseudo-online modes only analyze data in short time windows. Offline analysis is usually done with asynchronous BCIs, which restricts analysis to predefined time windows. Asynchronous BCI, compatible with online and pseudo-online modes, allows flexible mental activity duration. Offline processing tends to be more accurate, while online analysis is better for therapeutic applications. Pseudo-online implementation approximates online processing without real-time constraints. Many BCI studies being offline introduce biases compared to real-life scenarios, impacting classification algorithm performance. Approach: The objective of this research paper is therefore to extend the current MOABB framework, operating in offline mode, so as to allow a comparison of different algorithms in a pseudo-online setting with the use of a technology based on overlapping sliding windows. To do this will require the introduction of a idle state event in the dataset that takes into account all different possibilities that are not task thinking. To validate the performance of the algorithms we will use the normalized Matthews Correlation Coefficient (nMCC) and the Information Transfer Rate (ITR). Main results: We analyzed the state-of-the-art algorithms of the last 15 years over several Motor Imagery (MI) datasets composed by several subjects, showing the differences between the two approaches from a statistical point of view. Significance: The ability to analyze the performance of different algorithms in offline and pseudo-online modes will allow the BCI community to obtain more accurate and comprehensive reports regarding the performance of classification algorithms.