Vision-language foundation models have been incredibly successful in a wide range of downstream computer vision tasks using adaptation methods. However, due to the high cost of obtaining pre-training datasets, pairs with weak image-text correlation in the data exist in large numbers. We call them weak-paired samples. Due to the limitations of these weak-paired samples, the pre-training model are unable to mine all the knowledge from pre-training data. The existing adaptation methods do not consider the missing knowledge, which may lead to crucial task-related knowledge for the downstream tasks being ignored. To address this issue, we propose a new adaptation framework called Data Adaptive Traceback (DAT). Specifically, we utilize a zero-shot-based method to extract the most downstream task-related subset of the pre-training data to enable the downstream tasks. Furthermore, we adopt a pseudo-label-based semi-supervised technique to reuse the pre-training images and a vision-language contrastive learning method to address the confirmation bias issue in semi-supervised learning. We conduct extensive experiments that show our proposed DAT approach meaningfully improves various benchmark datasets performance over traditional adaptation methods by simply.
Machine learning models are vulnerable to tiny adversarial input perturbations optimized to cause a very large output error. To measure this vulnerability, we need reliable methods that can find such adversarial perturbations. For image classification models, evaluation methodologies have emerged that have stood the test of time. However, we argue that in the area of semantic segmentation, a good approximation of the sensitivity to adversarial perturbations requires significantly more effort than what is currently considered satisfactory. To support this claim, we re-evaluate a number of well-known robust segmentation models in an extensive empirical study. We propose new attacks and combine them with the strongest attacks available in the literature. We also analyze the sensitivity of the models in fine detail. The results indicate that most of the state-of-the-art models have a dramatically larger sensitivity to adversarial perturbations than previously reported. We also demonstrate a size-bias: small objects are often more easily attacked, even if the large objects are robust, a phenomenon not revealed by current evaluation metrics. Our results also demonstrate that a diverse set of strong attacks is necessary, because different models are often vulnerable to different attacks.
Various reversible deep neural networks (DNN) models have been proposed to reduce memory consumption in the training process. However, almost all existing reversible DNNs either require special non-standard architectures or are constructed by modifying existing DNN architectures considerably to enable reversibility. In this work we present the BDIA-transformer, which is an exact bit-level reversible transformer that uses an unchanged standard architecture for inference. The basic idea is to first treat each transformer block as the Euler integration approximation for solving an ordinary differential equation (ODE) and then incorporate the technique of bidirectional integration approximation (BDIA) into the neural architecture, together with activation quantization to make it exactly bit-level reversible. In the training process, we let a hyper-parameter $\gamma$ in BDIA-transformer randomly take one of the two values $\{0.5, -0.5\}$ per training sample per transformer block for averaging every two consecutive integration approximations. As a result, BDIA-transformer can be viewed as training an ensemble of ODE solvers parameterized by a set of binary random variables, which regularizes the model and results in improved validation accuracy. Lightweight side information per transformer block is required to be stored in the forward process to account for binary quantization loss to enable exact bit-level reversibility. In the inference procedure, the expectation $\mathbb{E}(\gamma)=0$ is taken to make the resulting architectures of BDIA-transformer identical to transformers up to activation quantization. Our experiments in both image classification and language translation show that BDIA-transformers outperform their conventional counterparts significantly in terms of validation performance while also requiring considerably less training memory.
Pre-trained vision-language models (VLMs) have enabled significant progress in open vocabulary computer vision tasks such as image classification, object detection and image segmentation. Some recent works have focused on extending VLMs to open vocabulary single label action classification in videos. However, previous methods fall short in holistic video understanding which requires the ability to simultaneously recognize multiple actions and entities e.g., objects in the video in an open vocabulary setting. We formulate this problem as open vocabulary multilabel video classification and propose a method to adapt a pre-trained VLM such as CLIP to solve this task. We leverage large language models (LLMs) to provide semantic guidance to the VLM about class labels to improve its open vocabulary performance with two key contributions. First, we propose an end-to-end trainable architecture that learns to prompt an LLM to generate soft attributes for the CLIP text-encoder to enable it to recognize novel classes. Second, we integrate a temporal modeling module into CLIP's vision encoder to effectively model the spatio-temporal dynamics of video concepts as well as propose a novel regularized finetuning technique to ensure strong open vocabulary classification performance in the video domain. Our extensive experimentation showcases the efficacy of our approach on multiple benchmark datasets.
Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial drawbacks. There exist numerous tasks in pathology, but one needs to build a model per task, i.e., a task-specific model, thereby increasing the number of models, training resources, and cost. Moreover, transferring arbitrary task-specific model to another task is still a challenging problem. Herein, we propose a task-agnostic generative and general pathology image classifier, so called GPC, that aims at learning from diverse kinds of pathology images and conducting numerous classification tasks in a unified model. GPC, equipped with a convolutional neural network and a Transformer-based language model, maps pathology images into a high-dimensional feature space and generates pertinent class labels as texts via the image-to-text classification mechanism. We evaluate GPC on six datasets for four different pathology image classification tasks. Experimental results show that GPC holds considerable potential for developing an effective and efficient universal model for pathology image analysis.
There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high costs. To address the challenges, we propose a generic, unified, and universal framework, called a continuous and adaptive learning model in pathology (CAMP), for pathology image classification. CAMP is a generative, efficient, and adaptive classification model that can continuously adapt to any classification task by leveraging pathology-specific prior knowledge and learning taskspecific knowledge with minimal computational cost and without forgetting the knowledge from the existing tasks. We evaluated CAMP on 22 datasets, including 1,171,526 patches and 11,811 pathology slides, across 17 classification tasks. CAMP achieves state-of-theart classification performance on a wide range of datasets and tasks at both patch- and slide-levels and reduces up to 94% of computation time and 85% of storage memory in comparison to the conventional classification models. Our results demonstrate that CAMP can offer a fundamental transformation in pathology image classification, paving the way for the fully digitized and computerized pathology practice.
Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and differences across various stages, anatomical locations and patients should be taken into account. However, recent research mainly focuses on the inner-contextual information in a single WSI, ignoring the correlations between slides. To verify whether introducing the slide inter-correlations can bring improvements to WSI representation learning, we propose a generic WSI analysis pipeline SlideGCD that considers the existing multi-instance learning (MIL) methods as the backbone and forge the WSI classification task as a node classification problem. More specifically, SlideGCD declares a node buffer that stores previous slide embeddings for subsequent extensive slide-based graph construction and conducts graph learning to explore the inter-correlations implied in the slide-based graph. Moreover, we frame the MIL classifier and graph learning into two parallel workflows and deploy the knowledge distillation to transfer the differentiable information to the graph neural network. The consistent performance boosting, brought by SlideGCD, of four previous state-of-the-art MIL methods is observed on two TCGA benchmark datasets. The code is available at https://github.com/HFUT-miaLab/SlideGCD.
Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in computer vision allow for accurate recognition of lesion regions with deep learning-based solutions. Such models, however, usually require extensive annotated datasets for training, which is often not the case in the considered task, where the number of available patient data samples is very limited. To deal with this problem, we propose a novel DeepCMorph model pre-trained to learn cell morphology and identify a large number of different cancer types. The model consists of two modules: the first one performs cell nuclei segmentation and annotates each cell type, and is trained on a combination of 8 publicly available datasets to ensure its high generalizability and robustness. The second module combines the obtained segmentation map with the original microscopy image and is trained for the downstream task. We pre-trained this module on the Pan-Cancer TCGA dataset consisting of over 270K tissue patches extracted from 8736 diagnostic slides from 7175 patients. The proposed solution achieved a new state-of-the-art performance on the dataset under consideration, detecting 32 cancer types with over 82% accuracy and outperforming all previously proposed solutions by more than 4%. We demonstrate that the resulting pre-trained model can be easily fine-tuned on smaller microscopy datasets, yielding superior results compared to the current top solutions and models initialized with ImageNet weights. The codes and pre-trained models presented in this paper are available at: https://github.com/aiff22/DeepCMorph
Continual Learning (CL) is crucial for enabling networks to dynamically adapt as they learn new tasks sequentially, accommodating new data and classes without catastrophic forgetting. Diverging from conventional perspectives on CL, our paper introduces a new perspective wherein forgetting could actually benefit the sequential learning paradigm. Specifically, we present BiasPruner, a CL framework that intentionally forgets spurious correlations in the training data that could lead to shortcut learning. Utilizing a new bias score that measures the contribution of each unit in the network to learning spurious features, BiasPruner prunes those units with the highest bias scores to form a debiased subnetwork preserved for a given task. As BiasPruner learns a new task, it constructs a new debiased subnetwork, potentially incorporating units from previous subnetworks, which improves adaptation and performance on the new task. During inference, BiasPruner employs a simple task-agnostic approach to select the best debiased subnetwork for predictions. We conduct experiments on three medical datasets for skin lesion classification and chest X-Ray classification and demonstrate that BiasPruner consistently outperforms SOTA CL methods in terms of classification performance and fairness. Our code is available here.
Efficient extraction of spectral sequences and geospatial information has always been a hot topic in hyperspectral image classification. In terms of spectral sequence feature capture, RNN and Transformer have become mainstream classification frameworks due to their long-range feature capture capabilities. In terms of spatial information aggregation, CNN enhances the receptive field to retain integrated spatial information as much as possible. However, the spectral feature-capturing architectures exhibit low computational efficiency, and CNNs lack the flexibility to perceive spatial contextual information. To address these issues, this paper proposes GraphMamba--an efficient graph structure learning vision Mamba classification framework that fully considers HSI characteristics to achieve deep spatial-spectral information mining. Specifically, we propose a novel hyperspectral visual GraphMamba processing paradigm (HVGM) that preserves spatial-spectral features by constructing spatial-spectral cubes and utilizes linear spectral encoding to enhance the operability of subsequent tasks. The core components of GraphMamba include the HyperMamba module for improving computational efficiency and the SpectralGCN module for adaptive spatial context awareness. The HyperMamba mitigates clutter interference by employing the global mask (GM) and introduces a parallel training inference architecture to alleviate computational bottlenecks. The SpatialGCN incorporates weighted multi-hop aggregation (WMA) spatial encoding to focus on highly correlated spatial structural features, thus flexibly aggregating contextual information while mitigating spatial noise interference. Extensive experiments were conducted on three different scales of real HSI datasets, and compared with the state-of-the-art classification frameworks, GraphMamba achieved optimal performance.
Data augmentation remains a widely utilized technique in deep learning, particularly in tasks such as image classification, semantic segmentation, and object detection. Among them, Copy-Paste is a simple yet effective method and gain great attention recently. However, existing Copy-Paste often overlook contextual relevance between source and target images, resulting in inconsistencies in generated outputs. To address this challenge, we propose a context-aware approach that integrates Bidirectional Latent Information Propagation (BLIP) for content extraction from source images. By matching extracted content information with category information, our method ensures cohesive integration of target objects using Segment Anything Model (SAM) and You Only Look Once (YOLO). This approach eliminates the need for manual annotation, offering an automated and user-friendly solution. Experimental evaluations across diverse datasets demonstrate the effectiveness of our method in enhancing data diversity and generating high-quality pseudo-images across various computer vision tasks.
We propose a novel hybrid Mamba-Transformer backbone, MambaVision, specifically tailored for vision applications. Our core contribution includes redesigning the Mamba formulation to enhance its capability for efficient modeling of visual features. Through a comprehensive ablation study, we demonstrate the feasibility of integrating Vision Transformers (ViT) with Mamba. Our results show that equipping the Mamba architecture with self-attention blocks in the final layers greatly improves its capacity to capture long-range spatial dependencies. Based on these findings, we introduce a family of MambaVision models with a hierarchical architecture to meet various design criteria. For classification on the ImageNet-1K dataset, MambaVision variants achieve state-of-the-art (SOTA) performance in terms of both Top-1 accuracy and throughput. In downstream tasks such as object detection, instance segmentation, and semantic segmentation on MS COCO and ADE20K datasets, MambaVision outperforms comparably sized backbones while demonstrating favorable performance. Code: https://github.com/NVlabs/MambaVision
Recently, the fractional Fourier transform (FrFT) has been integrated into distinct deep neural network (DNN) models such as transformers, sequence models, and convolutional neural networks (CNNs). In these studies, the fraction order is considered a hyperparameter and tuned manually to find the suitable values. By taking these one step further, we extend the scope of FrFT and introduce it as a trainable layer in various neural network architectures, where the fraction order is learned in the training stage along with the network weights. First, we mathematically show that fraction order can be updated through backpropagation in the network training phase. To support this formulation, we conduct extensive experiments encompassing image classification and time series prediction tasks on benchmark datasets. Our results show that the trainable FrFT layers alleviate the need to search for suitable fraction orders and improve performance over time and Fourier domain approaches.
This study introduces the Misclassification Likelihood Matrix (MLM) as a novel tool for quantifying the reliability of neural network predictions under distribution shifts. The MLM is obtained by leveraging softmax outputs and clustering techniques to measure the distances between the predictions of a trained neural network and class centroids. By analyzing these distances, the MLM provides a comprehensive view of the model's misclassification tendencies, enabling decision-makers to identify the most common and critical sources of errors. The MLM allows for the prioritization of model improvements and the establishment of decision thresholds based on acceptable risk levels. The approach is evaluated on the MNIST dataset using a Convolutional Neural Network (CNN) and a perturbed version of the dataset to simulate distribution shifts. The results demonstrate the effectiveness of the MLM in assessing the reliability of predictions and highlight its potential in enhancing the interpretability and risk mitigation capabilities of neural networks. The implications of this work extend beyond image classification, with ongoing applications in autonomous systems, such as self-driving cars, to improve the safety and reliability of decision-making in complex, real-world environments.
Nonlinear activation functions are pivotal to the success of deep neural nets, and choosing the appropriate activation function can significantly affect their performance. Most networks use fixed activation functions (e.g., ReLU, GELU, etc.), and this choice might limit their expressiveness. Furthermore, different layers may benefit from diverse activation functions. Consequently, there has been a growing interest in trainable activation functions. In this paper, we introduce DiTAC, a trainable highly-expressive activation function based on an efficient diffeomorphic transformation (called CPAB). Despite introducing only a negligible number of trainable parameters, DiTAC enhances model expressiveness and performance, often yielding substantial improvements. It also outperforms existing activation functions (regardless whether the latter are fixed or trainable) in tasks such as semantic segmentation, image generation, regression problems, and image classification. Our code is available at https://github.com/BGU-CS-VIL/DiTAC.
Vision Transformers (ViTs) have achieved significant advancement in computer vision tasks due to their powerful modeling capacity. However, their performance notably degrades when trained with insufficient data due to lack of inherent inductive biases. Distilling knowledge and inductive biases from a Convolutional Neural Network (CNN) teacher has emerged as an effective strategy for enhancing the generalization of ViTs on limited datasets. Previous approaches to Knowledge Distillation (KD) have pursued two primary paths: some focused solely on distilling the logit distribution from CNN teacher to ViT student, neglecting the rich semantic information present in intermediate features due to the structural differences between them. Others integrated feature distillation along with logit distillation, yet this introduced alignment operations that limits the amount of knowledge transferred due to mismatched architectures and increased the computational overhead. To this end, this paper presents Hybrid Data-efficient Knowledge Distillation (HDKD) paradigm which employs a CNN teacher and a hybrid student. The choice of hybrid student serves two main aspects. First, it leverages the strengths of both convolutions and transformers while sharing the convolutional structure with the teacher model. Second, this shared structure enables the direct application of feature distillation without any information loss or additional computational overhead. Additionally, we propose an efficient light-weight convolutional block named Mobile Channel-Spatial Attention (MBCSA), which serves as the primary convolutional block in both teacher and student models. Extensive experiments on two medical public datasets showcase the superiority of HDKD over other state-of-the-art models and its computational efficiency. Source code at: https://github.com/omarsherif200/HDKD
Recently, vision-language pre-trained models have emerged in computational pathology. Previous works generally focused on the alignment of image-text pairs via the contrastive pre-training paradigm. Such pre-trained models have been applied to pathology image classification in zero-shot learning or transfer learning fashion. Herein, we hypothesize that the pre-trained vision-language models can be utilized for quantitative histopathology image analysis through a simple image-to-text retrieval. To this end, we propose a Text-based Quantitative and Explainable histopathology image analysis, which we call TQx. Given a set of histopathology images, we adopt a pre-trained vision-language model to retrieve a word-of-interest pool. The retrieved words are then used to quantify the histopathology images and generate understandable feature embeddings due to the direct mapping to the text description. To evaluate the proposed method, the text-based embeddings of four histopathology image datasets are utilized to perform clustering and classification tasks. The results demonstrate that TQx is able to quantify and analyze histopathology images that are comparable to the prevalent visual models in computational pathology.
Slide-level classification for whole-slide images (WSIs) has been widely recognized as a crucial problem in digital and computational pathology. Current approaches commonly consider WSIs as a bag of cropped patches and process them via multiple instance learning due to the large number of patches, which cannot fully explore the relationship among patches; in other words, the global information cannot be fully incorporated into decision making. Herein, we propose an efficient and effective slide-level classification model, named as FALFormer, that can process a WSI as a whole so as to fully exploit the relationship among the entire patches and to improve the classification performance. FALFormer is built based upon Transformers and self-attention mechanism. To lessen the computational burden of the original self-attention mechanism and to process the entire patches together in a WSI, FALFormer employs Nystr\"om self-attention which approximates the computation by using a smaller number of tokens or landmarks. For effective learning, FALFormer introduces feature-aware landmarks to enhance the representation power of the landmarks and the quality of the approximation. We systematically evaluate the performance of FALFormer using two public datasets, including CAMELYON16 and TCGA-BRCA. The experimental results demonstrate that FALFormer achieves superior performance on both datasets, outperforming the state-of-the-art methods for the slide-level classification. This suggests that FALFormer can facilitate an accurate and precise analysis of WSIs, potentially leading to improved diagnosis and prognosis on WSIs.
Hyperspectral image classification, a task that assigns pre-defined classes to each pixel in a hyperspectral image of remote sensing scenes, often faces challenges due to the neglect of correlations between spectrally similar pixels. This oversight can lead to inaccurate edge definitions and difficulties in managing minor spectral variations in contiguous areas. To address these issues, we introduce the novel Dual-stage Spectral Supertoken Classifier (DSTC), inspired by superpixel concepts. DSTC employs spectrum-derivative-based pixel clustering to group pixels with similar spectral characteristics into spectral supertokens. By projecting the classification of these tokens onto the image space, we achieve pixel-level results that maintain regional classification consistency and precise boundary. Moreover, recognizing the diversity within tokens, we propose a class-proportion-based soft label. This label adaptively assigns weights to different categories based on their prevalence, effectively managing data distribution imbalances and enhancing classification performance. Comprehensive experiments on WHU-OHS, IP, KSC, and UP datasets corroborate the robust classification capabilities of DSTC and the effectiveness of its individual components. Code will be publicly available at https://github.com/laprf/DSTC.
The cornerstone of autonomous vehicles (AV) is a solid perception system, where camera encoders play a crucial role. Existing works usually leverage pre-trained Convolutional Neural Networks (CNN) or Vision Transformers (ViTs) designed for general vision tasks, such as image classification, segmentation, and 2D detection. Although those well-known architectures have achieved state-of-the-art accuracy in AV-related tasks, e.g., 3D Object Detection, there remains significant potential for improvement in network design due to the nuanced complexities of industrial-level AV dataset. Moreover, existing public AV benchmarks usually contain insufficient data, which might lead to inaccurate evaluation of those architectures.To reveal the AV-specific model insights, we start from a standard general-purpose encoder, ConvNeXt and progressively transform the design. We adjust different design parameters including width and depth of the model, stage compute ratio, attention mechanisms, and input resolution, supported by systematic analysis to each modifications. This customization yields an architecture optimized for AV camera encoder achieving 8.79% mAP improvement over the baseline. We believe our effort could become a sweet cookbook of image encoders for AV and pave the way to the next-level drive system.