Early detection of skin abnormalities plays a crucial role in diagnosing and treating skin cancer. Segmentation of affected skin regions using AI-powered devices is relatively common and supports the diagnostic process. However, achieving high performance remains a significant challenge due to the need for high-resolution images and the often unclear boundaries of individual lesions. At the same time, medical devices require segmentation models to have a small memory foot-print and low computational cost. Based on these requirements, we introduce a novel lightweight model called MambaU-Lite, which combines the strengths of Mamba and CNN architectures, featuring just over 400K parameters and a computational cost of more than 1G flops. To enhance both global context and local feature extraction, we propose the P-Mamba block, a novel component that incorporates VSS blocks along-side multiple pooling layers, enabling the model to effectively learn multiscale features and enhance segmentation performance. We evaluate the model's performance on two skin datasets, ISIC2018 and PH2, yielding promising results. Our source code will be made publicly available at: https://github.com/nqnguyen812/MambaU-Lite.
Open compound domain adaptation (OCDA) is a practical domain adaptation problem that consists of a source domain, target compound domain, and unseen open domain. In this problem, the absence of domain labels and pixel-level segmentation labels for both compound and open domains poses challenges to the direct application of existing domain adaptation and generalization methods. To address this issue, we propose Amplitude-based curriculum learning and a Hopfield segmentation model for Open Compound Domain Adaptation (AH-OCDA). Our method comprises two complementary components: 1) amplitude-based curriculum learning and 2) Hopfield segmentation model. Without prior knowledge of target domains within the compound domains, amplitude-based curriculum learning gradually induces the semantic segmentation model to adapt from the near-source compound domain to the far-source compound domain by ranking unlabeled compound domain images through Fast Fourier Transform (FFT). Additionally, the Hopfield segmentation model maps segmentation feature distributions from arbitrary domains to the feature distributions of the source domain. AH-OCDA achieves state-of-the-art performance on two OCDA benchmarks and extended open domains, demonstrating its adaptability to continuously changing compound domains and unseen open domains.
Medical imaging is essential in healthcare to provide key insights into patient anatomy and pathology, aiding in diagnosis and treatment. Non-invasive techniques such as X-ray, Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and Ultrasound (US), capture detailed images of organs, tissues, and abnormalities. Effective analysis of these images requires precise segmentation to delineate regions of interest (ROI), such as organs or lesions. Traditional segmentation methods, relying on manual feature-extraction, are labor-intensive and vary across experts. Recent advancements in Artificial Intelligence (AI) and Deep Learning (DL), particularly convolutional models such as U-Net and its variants (U-Net++ and U-Net 3+), have transformed medical image segmentation (MIS) by automating the process and enhancing accuracy. These models enable efficient, precise pixel-wise classification across various imaging modalities, overcoming the limitations of manual segmentation. This review explores various medical imaging techniques, examines the U-Net architectures and their adaptations, and discusses their application across different modalities. It also identifies common challenges in MIS and proposes potential solutions.
Human pose estimation methods work well on separated people but struggle with multi-body scenarios. Recent work has addressed this problem by conditioning pose estimation with detected bounding boxes or bottom-up-estimated poses. Unfortunately, all of these approaches overlooked segmentation masks and their connection to estimated keypoints. We condition pose estimation model by segmentation masks instead of bounding boxes to improve instance separation. This improves top-down pose estimation in multi-body scenarios but does not fix detection errors. Consequently, we develop BBox-Mask-Pose (BMP), integrating detection, segmentation and pose estimation into self-improving feedback loop. We adapt detector and pose estimation model for conditioning by instance masks and use Segment Anything as pose-to-mask model to close the circle. With only small models, BMP is superior to top-down methods on OCHuman dataset and to detector-free methods on COCO dataset, combining the best from both approaches and matching state of art performance in both settings. Code is available on https://mirapurkrabek.github.io/BBox-Mask-Pose.
Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds or thousands of annotated cells for fine-tuning. We introduce CellSeg1, a practical solution for segmenting cells of arbitrary morphology and modality with a few dozen cell annotations in 1 image. By adopting Low-Rank Adaptation of the Segment Anything Model (SAM), we achieve robust cell segmentation. Tested on 19 diverse cell datasets, CellSeg1 trained on 1 image achieved 0.81 average mAP at 0.5 IoU, performing comparably to existing models trained on over 500 images. It also demonstrated superior generalization in cross-dataset tests on TissueNet. We found that high-quality annotation of a few dozen densely packed cells of varied sizes is key to effective segmentation. CellSeg1 provides an efficient solution for cell segmentation with minimal annotation effort.
Medical image segmentation is a critical aspect of modern medical research and clinical practice. Despite the remarkable performance of Convolutional Neural Networks (CNNs) in this domain, they inherently struggle to capture long-range dependencies within images. Transformers, on the other hand, are naturally adept at modeling global context but often face challenges in capturing local features effectively. Therefore, we presents FAN-UNet, a novel architecture that combines the strengths of Fourier Analysis Network (FAN)-based vision backbones and the U-Net architecture, effectively addressing the challenges of long-range dependency and periodicity modeling in biomedical image segmentation tasks. The proposed Vision-FAN layer integrates the FAN layer and self-attention mechanisms, leveraging Fourier analysis to enable the model to effectively capture both long-range dependencies and periodic relationships. Extensive experiments on various medical imaging datasets demonstrate that FAN-UNet achieves a favorable balance between model complexity and performance, validating its effectiveness and practicality for medical image segmentation tasks.
Segment Anything Model 2 (SAM 2) has emerged as a powerful tool for video object segmentation and tracking anything. Key components of SAM 2 that drive the impressive video object segmentation performance include a large multistage image encoder for frame feature extraction and a memory mechanism that stores memory contexts from past frames to help current frame segmentation. The high computation complexity of multistage image encoder and memory module has limited its applications in real-world tasks, e.g., video object segmentation on mobile devices. To address this limitation, we propose EfficientTAMs, lightweight track anything models that produce high-quality results with low latency and model size. Our idea is based on revisiting the plain, nonhierarchical Vision Transformer (ViT) as an image encoder for video object segmentation, and introducing an efficient memory module, which reduces the complexity for both frame feature extraction and memory computation for current frame segmentation. We take vanilla lightweight ViTs and efficient memory module to build EfficientTAMs, and train the models on SA-1B and SA-V datasets for video object segmentation and track anything tasks. We evaluate on multiple video segmentation benchmarks including semi-supervised VOS and promptable video segmentation, and find that our proposed EfficientTAM with vanilla ViT perform comparably to SAM 2 model (HieraB+SAM 2) with ~2x speedup on A100 and ~2.4x parameter reduction. On segment anything image tasks, our EfficientTAMs also perform favorably over original SAM with ~20x speedup on A100 and ~20x parameter reduction. On mobile devices such as iPhone 15 Pro Max, our EfficientTAMs can run at ~10 FPS for performing video object segmentation with reasonable quality, highlighting the capability of small models for on-device video object segmentation applications.
Segmentation has long been essential in computer vision due to its numerous real-world applications. However, most traditional deep learning and machine learning models need help to capture geometric features such as size and convexity of the segmentation targets, resulting in suboptimal outcomes. To resolve this problem, we propose using a CovHuSeg algorithm to solve the problem of kidney glomeruli segmentation. This simple post-processing method is specified to adapt to the segmentation of ball-shaped anomalies, including the glomerulus. Unlike other post-processing methods, the CovHuSeg algorithm assures that the outcome mask does not have holes in it or comes in unusual shapes that are impossible to be the shape of a glomerulus. We illustrate the effectiveness of our method by experimenting with multiple deep-learning models in the context of segmentation on kidney pathology images. The results show that all models have increased accuracy when using the CovHuSeg algorithm.
Integrating 2D mammography with 3D magnetic resonance imaging (MRI) is crucial for improving breast cancer diagnosis and treatment planning. However, this integration is challenging due to differences in imaging modalities and the need for precise tissue segmentation and alignment. This paper addresses these challenges by enhancing biomechanical breast models in two main aspects: improving tissue identification using nnU-Net segmentation models and evaluating finite element (FE) biomechanical solvers, specifically comparing NiftySim and FEBio. We performed a detailed six-class segmentation of breast MRI data using the nnU-Net architecture, achieving Dice Coefficients of 0.94 for fat, 0.88 for glandular tissue, and 0.87 for pectoral muscle. The overall foreground segmentation reached a mean Dice Coefficient of 0.83 through an ensemble of 2D and 3D U-Net configurations, providing a solid foundation for 3D reconstruction and biomechanical modeling. The segmented data was then used to generate detailed 3D meshes and develop biomechanical models using NiftySim and FEBio, which simulate breast tissue's physical behaviors under compression. Our results include a comparison between NiftySim and FEBio, providing insights into the accuracy and reliability of these simulations in studying breast tissue responses under compression. The findings of this study have the potential to improve the integration of 2D and 3D imaging modalities, thereby enhancing diagnostic accuracy and treatment planning for breast cancer.
There has been extensive progress in the reconstruction and generation of 4D scenes from monocular casually-captured video. While these tasks rely heavily on known camera poses, the problem of finding such poses using structure-from-motion (SfM) often depends on robustly separating static from dynamic parts of a video. The lack of a robust solution to this problem limits the performance of SfM camera-calibration pipelines. We propose a novel approach to video-based motion segmentation to identify the components of a scene that are moving w.r.t. a fixed world frame. Our simple but effective iterative method, RoMo, combines optical flow and epipolar cues with a pre-trained video segmentation model. It outperforms unsupervised baselines for motion segmentation as well as supervised baselines trained from synthetic data. More importantly, the combination of an off-the-shelf SfM pipeline with our segmentation masks establishes a new state-of-the-art on camera calibration for scenes with dynamic content, outperforming existing methods by a substantial margin.
Anomaly segmentation is a valuable computer vision task for safety-critical applications that need to be aware of unexpected events. Current state-of-the-art (SOTA) scene-level anomaly segmentation approaches rely on diverse inlier class labels during training, limiting their ability to leverage vast unlabeled datasets and pre-trained vision encoders. These methods may underperform in domains with reduced color diversity and limited object classes. Conversely, existing unsupervised methods struggle with anomaly segmentation with the diverse scenes of less restricted domains. To address these challenges, we introduce FlowCLAS, a novel self-supervised framework that utilizes vision foundation models to extract rich features and employs a normalizing flow network to learn their density distribution. We enhance the model's discriminative power by incorporating Outlier Exposure and contrastive learning in the latent space. FlowCLAS significantly outperforms all existing methods on the ALLO anomaly segmentation benchmark for space robotics and demonstrates competitive results on multiple road anomaly segmentation benchmarks for autonomous driving, including Fishyscapes Lost&Found and Road Anomaly. These results highlight FlowCLAS's effectiveness in addressing the unique challenges of space anomaly segmentation while retaining SOTA performance in the autonomous driving domain without reliance on inlier segmentation labels.
3D scene understanding has become an essential area of research with applications in autonomous driving, robotics, and augmented reality. Recently, 3D Gaussian Splatting (3DGS) has emerged as a powerful approach, combining explicit modeling with neural adaptability to provide efficient and detailed scene representations. However, three major challenges remain in leveraging 3DGS for scene understanding: 1) an imbalance between appearance and semantics, where dense Gaussian usage for fine-grained texture modeling does not align with the minimal requirements for semantic attributes; 2) inconsistencies between appearance and semantics, as purely appearance-based Gaussians often misrepresent object boundaries; and 3) reliance on top-down instance segmentation methods, which struggle with uneven category distributions, leading to over- or under-segmentation. In this work, we propose InstanceGaussian, a method that jointly learns appearance and semantic features while adaptively aggregating instances. Our contributions include: i) a novel Semantic-Scaffold-GS representation balancing appearance and semantics to improve feature representations and boundary delineation; ii) a progressive appearance-semantic joint training strategy to enhance stability and segmentation accuracy; and iii) a bottom-up, category-agnostic instance aggregation approach that addresses segmentation challenges through farthest point sampling and connected component analysis. Our approach achieves state-of-the-art performance in category-agnostic, open-vocabulary 3D point-level segmentation, highlighting the effectiveness of the proposed representation and training strategies. Project page: https://lhj-git.github.io/InstanceGaussian/
We present Track Anything Behind Everything (TABE), a novel dataset, pipeline, and evaluation framework for zero-shot amodal completion from visible masks. Unlike existing methods that require pretrained class labels, our approach uses a single query mask from the first frame where the object is visible, enabling flexible, zero-shot inference. Our dataset, TABE-51 provides highly accurate ground truth amodal segmentation masks without the need for human estimation or 3D reconstruction. Our TABE pipeline is specifically designed to handle amodal completion, even in scenarios where objects are completely occluded. We also introduce a specialised evaluation framework that isolates amodal completion performance, free from the influence of traditional visual segmentation metrics.
In medical image analysis, achieving fast, efficient, and accurate segmentation is essential for automated diagnosis and treatment. Although recent advancements in deep learning have significantly improved segmentation accuracy, current models often face challenges in adaptability and generalization, particularly when processing multi-modal medical imaging data. These limitations stem from the substantial variations between imaging modalities and the inherent complexity of medical data. To address these challenges, we propose the Strategy-driven Interactive Segmentation Model (SISeg), built on SAM2, which enhances segmentation performance across various medical imaging modalities by integrating a selection engine. To mitigate memory bottlenecks and optimize prompt frame selection during the inference of 2D image sequences, we developed an automated system, the Adaptive Frame Selection Engine (AFSE). This system dynamically selects the optimal prompt frames without requiring extensive prior medical knowledge and enhances the interpretability of the model's inference process through an interactive feedback mechanism. We conducted extensive experiments on 10 datasets covering 7 representative medical imaging modalities, demonstrating the SISeg model's robust adaptability and generalization in multi-modal tasks. The project page and code will be available at: [URL].
Open-Vocabulary Segmentation (OVS) aims at segmenting images from free-form textual concepts without predefined training classes. While existing vision-language models such as CLIP can generate segmentation masks by leveraging coarse spatial information from Vision Transformers, they face challenges in spatial localization due to their global alignment of image and text features. Conversely, self-supervised visual models like DINO excel in fine-grained visual encoding but lack integration with language. To bridge this gap, we present Talk2DINO, a novel hybrid approach that combines the spatial accuracy of DINOv2 with the language understanding of CLIP. Our approach aligns the textual embeddings of CLIP to the patch-level features of DINOv2 through a learned mapping function without the need to fine-tune the underlying backbones. At training time, we exploit the attention maps of DINOv2 to selectively align local visual patches with textual embeddings. We show that the powerful semantic and localization abilities of Talk2DINO can enhance the segmentation process, resulting in more natural and less noisy segmentations, and that our approach can also effectively distinguish foreground objects from the background. Experimental results demonstrate that Talk2DINO achieves state-of-the-art performance across several unsupervised OVS benchmarks. Source code and models are publicly available at: https://lorebianchi98.github.io/Talk2DINO/.
Moving object detection and segmentation from a single moving camera is a challenging task, requiring an understanding of recognition, motion and 3D geometry. Combining both recognition and reconstruction boils down to a fusion problem, where appearance and motion features need to be combined for classification and segmentation. In this paper, we present a novel fusion architecture for monocular motion segmentation - M3Former, which leverages the strong performance of transformers for segmentation and multi-modal fusion. As reconstructing motion from monocular video is ill-posed, we systematically analyze different 2D and 3D motion representations for this problem and their importance for segmentation performance. Finally, we analyze the effect of training data and show that diverse datasets are required to achieve SotA performance on Kitti and Davis.
Text-to-image diffusion models have emerged as powerful priors for real-world image super-resolution (Real-ISR). However, existing methods may produce unintended results due to noisy text prompts and their lack of spatial information. In this paper, we present HoliSDiP, a framework that leverages semantic segmentation to provide both precise textual and spatial guidance for diffusion-based Real-ISR. Our method employs semantic labels as concise text prompts while introducing dense semantic guidance through segmentation masks and our proposed Segmentation-CLIP Map. Extensive experiments demonstrate that HoliSDiP achieves significant improvement in image quality across various Real-ISR scenarios through reduced prompt noise and enhanced spatial control.
Segmentation of Earth observation (EO) satellite data is critical for natural hazard analysis and disaster response. However, processing EO data at ground stations introduces delays due to data transmission bottlenecks and communication windows. Using segmentation models capable of near-real-time data analysis onboard satellites can therefore improve response times. This study presents a proof-of-concept using MobileSAM, a lightweight, pre-trained segmentation model, onboard Unibap iX10-100 satellite hardware. We demonstrate the segmentation of water bodies from Sentinel-2 satellite imagery and integrate MobileSAM with PASEOS, an open-source Python module that simulates satellite operations. This integration allows us to evaluate MobileSAM's performance under simulated conditions of a satellite constellation. Our research investigates the potential of fine-tuning MobileSAM in a decentralised way onboard multiple satellites in rapid response to a disaster. Our findings show that MobileSAM can be rapidly fine-tuned and benefits from decentralised learning, considering the constraints imposed by the simulated orbital environment. We observe improvements in segmentation performance with minimal training data and fast fine-tuning when satellites frequently communicate model updates. This study contributes to the field of onboard AI by emphasising the benefits of decentralised learning and fine-tuning pre-trained models for rapid response scenarios. Our work builds on recent related research at a critical time; as extreme weather events increase in frequency and magnitude, rapid response with onboard data analysis is essential.
Purpose: To explore best-practice approaches for generating synthetic chest X-ray images and augmenting medical imaging datasets to optimize the performance of deep learning models in downstream tasks like classification and segmentation. Materials and Methods: We utilized a latent diffusion model to condition the generation of synthetic chest X-rays on text prompts and/or segmentation masks. We explored methods like using a proxy model and using radiologist feedback to improve the quality of synthetic data. These synthetic images were then generated from relevant disease information or geometrically transformed segmentation masks and added to ground truth training set images from the CheXpert, CANDID-PTX, SIIM, and RSNA Pneumonia datasets to measure improvements in classification and segmentation model performance on the test sets. F1 and Dice scores were used to evaluate classification and segmentation respectively. One-tailed t-tests with Bonferroni correction assessed the statistical significance of performance improvements with synthetic data. Results: Across all experiments, the synthetic data we generated resulted in a maximum mean classification F1 score improvement of 0.150453 (CI: 0.099108-0.201798; P=0.0031) compared to using only real data. For segmentation, the maximum Dice score improvement was 0.14575 (CI: 0.108267-0.183233; P=0.0064). Conclusion: Best practices for generating synthetic chest X-ray images for downstream tasks include conditioning on single-disease labels or geometrically transformed segmentation masks, as well as potentially using proxy modeling for fine-tuning such generations.
In the radiation therapy of nasopharyngeal carcinoma (NPC), clinicians typically delineate the gross tumor volume (GTV) using non-contrast planning computed tomography to ensure accurate radiation dose delivery. However, the low contrast between tumors and adjacent normal tissues necessitates that radiation oncologists manually delineate the tumors, often relying on diagnostic MRI for guidance. % In this study, we propose a novel approach to directly segment NPC gross tumors on non-contrast planning CT images, circumventing potential registration errors when aligning MRI or MRI-derived tumor masks to planning CT. To address the low contrast issues between tumors and adjacent normal structures in planning CT, we introduce a 3D Semantic Asymmetry Tumor segmentation (SATs) method. Specifically, we posit that a healthy nasopharyngeal region is characteristically bilaterally symmetric, whereas the emergence of nasopharyngeal carcinoma disrupts this symmetry. Then, we propose a Siamese contrastive learning segmentation framework that minimizes the voxel-wise distance between original and flipped areas without tumor and encourages a larger distance between original and flipped areas with tumor. Thus, our approach enhances the sensitivity of features to semantic asymmetries. % Extensive experiments demonstrate that the proposed SATs achieves the leading NPC GTV segmentation performance in both internal and external testing, \emph{e.g.}, with at least 2\% absolute Dice score improvement and 12\% average distance error reduction when compared to other state-of-the-art methods in the external testing.