Previous research on retinal vessel segmentation is targeted at a specific image domain, mostly color fundus photography (CFP). In this paper we make a brave attempt to attack a more challenging task of broad-domain retinal vessel segmentation (BD-RVS), which is to develop a unified model applicable to varied domains including CFP, SLO, UWF, OCTA and FFA. To that end, we propose Dual Convoltuional Prompting (DCP) that learns to extract domain-specific features by localized prompting along both position and channel dimensions. DCP is designed as a plug-in module that can effectively turn a R2AU-Net based vessel segmentation network to a unified model, yet without the need of modifying its network structure. For evaluation we build a broad-domain set using five public domain-specific datasets including ROSSA, FIVES, IOSTAR, PRIME-FP20 and VAMPIRE. In order to benchmark BD-RVS on the broad-domain dataset, we re-purpose a number of existing methods originally developed in other contexts, producing eight baseline methods in total. Extensive experiments show the the proposed method compares favorably against the baselines for BD-RVS.
Gastrointestinal (GI) bleeding is a serious medical condition that presents significant diagnostic challenges, particularly in settings with limited access to healthcare resources. Wireless Capsule Endoscopy (WCE) has emerged as a powerful diagnostic tool for visualizing the GI tract, but it requires time-consuming manual analysis by experienced gastroenterologists, which is prone to human error and inefficient given the increasing number of patients.To address this challenge, we propose ClassifyViStA, an AI-based framework designed for the automated detection and classification of bleeding and non-bleeding frames from WCE videos. The model consists of a standard classification path, augmented by two specialized branches: an implicit attention branch and a segmentation branch.The attention branch focuses on the bleeding regions, while the segmentation branch generates accurate segmentation masks, which are used for classification and interpretability. The model is built upon an ensemble of ResNet18 and VGG16 architectures to enhance classification performance. For the bleeding region detection, we implement a Soft Non-Maximum Suppression (Soft NMS) approach with YOLOv8, which improves the handling of overlapping bounding boxes, resulting in more accurate and nuanced detections.The system's interpretability is enhanced by using the segmentation masks to explain the classification results, offering insights into the decision-making process similar to the way a gastroenterologist identifies bleeding regions. Our approach not only automates the detection of GI bleeding but also provides an interpretable solution that can ease the burden on healthcare professionals and improve diagnostic efficiency. Our code is available at ClassifyViStA.
Accurate detection and segmentation of gastrointestinal bleeding are critical for diagnosing diseases such as peptic ulcers and colorectal cancer. This study proposes a two-stage framework that decouples classification and grounding to address the inherent challenges posed by traditional Multi-Task Learning models, which jointly optimizes classification and segmentation. Our approach separates these tasks to achieve targeted optimization for each. The model first classifies images as bleeding or non-bleeding, thereby isolating subsequent grounding from inter-task interference and label heterogeneity. To further enhance performance, we incorporate Stochastic Weight Averaging and Test-Time Augmentation, which improve model robustness against domain shifts and annotation inconsistencies. Our method is validated on the Auto-WCEBleedGen Challenge V2 Challenge dataset and achieving second place. Experimental results demonstrate significant improvements in classification accuracy and segmentation precision, especially on sequential datasets with consistent visual patterns. This study highlights the practical benefits of a two-stage strategy for medical image analysis and sets a new standard for GI bleeding detection and segmentation. Our code is publicly available at this GitHub repository.
This paper introduces a novel synthetic dataset that captures urban scenes under a variety of weather conditions, providing pixel-perfect, ground-truth-aligned images to facilitate effective feature alignment across domains. Additionally, we propose a method for domain adaptation and generalization that takes advantage of the multiple versions of each scene, enforcing feature consistency across different weather scenarios. Our experimental results demonstrate the impact of our dataset in improving performance across several alignment metrics, addressing key challenges in domain adaptation and generalization for segmentation tasks. This research also explores critical aspects of synthetic data generation, such as optimizing the balance between the volume and variability of generated images to enhance segmentation performance. Ultimately, this work sets forth a new paradigm for synthetic data generation and domain adaptation.
The challenges of road network segmentation demand an algorithm capable of adapting to the sparse and irregular shapes, as well as the diverse context, which often leads traditional encoding-decoding methods and simple Transformer embeddings to failure. We introduce a computationally efficient and powerful framework for elegant road-aware segmentation. Our method, called URoadNet, effectively encodes fine-grained local road connectivity and holistic global topological semantics while decoding multiscale road network information. URoadNet offers a novel alternative to the U-Net architecture by integrating connectivity attention, which can exploit intra-road interactions across multi-level sampling features with reduced computational complexity. This local interaction serves as valuable prior information for learning global interactions between road networks and the background through another integrality attention mechanism. The two forms of sparse attention are arranged alternatively and complementarily, and trained jointly, resulting in performance improvements without significant increases in computational complexity. Extensive experiments on various datasets with different resolutions, including Massachusetts, DeepGlobe, SpaceNet, and Large-Scale remote sensing images, demonstrate that URoadNet outperforms state-of-the-art techniques. Our approach represents a significant advancement in the field of road network extraction, providing a computationally feasible solution that achieves high-quality segmentation results.
Deep neural networks have shown outstanding performance in computer vision tasks such as semantic segmentation and have defined the state-of-the-art. However, these segmentation models are trained on a closed and predefined set of semantic classes, which leads to significant prediction failures in open-world scenarios on unknown objects. As this behavior prevents the application in safety-critical applications such as automated driving, the detection and segmentation of these objects from outside their predefined semantic space (out-of-distribution (OOD) objects) is of the utmost importance. In this work, we present a multi-scale OOD segmentation method that exploits the confidence information of a foreground-background segmentation model. While semantic segmentation models are trained on specific classes, this restriction does not apply to foreground-background methods making them suitable for OOD segmentation. We consider the per pixel confidence score of the model prediction which is close to 1 for a pixel in a foreground object. By aggregating these confidence values for different sized patches, objects of various sizes can be identified in a single image. Our experiments show improved performance of our method in OOD segmentation compared to comparable baselines in the SegmentMeIfYouCan benchmark.
With the rapid development of deep learning and computer vision technologies, medical image segmentation plays a crucial role in the early diagnosis of breast cancer. However, due to the characteristics of breast ultrasound images, such as low contrast, speckle noise, and the highly diverse morphology of tumors, existing segmentation methods exhibit significant limitations in terms of accuracy and robustness. To address these challenges, this study proposes a PINN-based and Enhanced Multi-Scale Feature Fusion Network. The network introduces a Hierarchical Aggregation Encoder in the backbone, which efficiently integrates and globally models multi-scale features through several structural innovations and a novel PCAM module. In the decoder section, a Multi-Scale Feature Refinement Decoder is employed, which, combined with a Multi-Scale Supervision Mechanism and a correction module, significantly improves segmentation accuracy and adaptability. Additionally, the loss function incorporating the PINN mechanism introduces physical constraints during the segmentation process, enhancing the model's ability to accurately delineate tumor boundaries. Comprehensive evaluations on two publicly available breast ultrasound datasets, BUSIS and BUSI, demonstrate that the proposed method outperforms previous segmentation approaches in terms of segmentation accuracy and robustness, particularly under conditions of complex noise and low contrast, effectively improving the accuracy and reliability of tumor segmentation. This method provides a more precise and robust solution for computer-aided diagnosis of breast ultrasound images.
Manipulating articulated objects with robotic arms is challenging due to the complex kinematic structure, which requires precise part segmentation for efficient manipulation. In this work, we introduce a novel superpoint-based perception method designed to improve part segmentation in 3D point clouds of articulated objects. We propose a learnable, part-aware superpoint generation technique that efficiently groups points based on their geometric and semantic similarities, resulting in clearer part boundaries. Furthermore, by leveraging the segmentation capabilities of the 2D foundation model SAM, we identify the centers of pixel regions and select corresponding superpoints as candidate query points. Integrating a query-based transformer decoder further enhances our method's ability to achieve precise part segmentation. Experimental results on the GAPartNet dataset show that our method outperforms existing state-of-the-art approaches in cross-category part segmentation, achieving AP50 scores of 77.9% for seen categories (4.4% improvement) and $39.3\%$ for unseen categories (11.6% improvement), with superior results in 5 out of 9 part categories for seen objects and outperforming all previous methods across all part categories for unseen objects.
With the rapid advancement of deep learning, the model robustness has become a significant research hotspot, \ie, adversarial attacks on deep neural networks. Existing works primarily focus on image classification tasks, aiming to alter the model's predicted labels. Due to the output complexity and deeper network architectures, research on adversarial examples for segmentation models is still limited, particularly for universal adversarial perturbations. In this paper, we propose a novel universal adversarial attack method designed for segmentation models, which includes dual feature separation and low-frequency scattering modules. The two modules guide the training of adversarial examples in the pixel and frequency space, respectively. Experiments demonstrate that our method achieves high attack success rates surpassing the state-of-the-art methods, and exhibits strong transferability across different models.
Despite the advances in learning-based image segmentation approach, the accurate segmentation of cardiac structures from magnetic resonance imaging (MRI) remains a critical challenge. While existing automatic segmentation methods have shown promise, they still require extensive manual corrections of the segmentation results by human experts, particularly in complex regions such as the basal and apical parts of the heart. Recent efforts have been made on developing interactive image segmentation methods that enable human-in-the-loop learning. However, they are semi-automatic and inefficient, due to their reliance on click-based prompts, especially for 3D cardiac MRI volumes. To address these limitations, we propose VerSe, a Versatile Segmentation framework to unify automatic and interactive segmentation through mutiple queries. Our key innovation lies in the joint learning of object and click queries as prompts for a shared segmentation backbone. VerSe supports both fully automatic segmentation, through object queries, and interactive mask refinement, by providing click queries when needed. With the proposed integrated prompting scheme, VerSe demonstrates significant improvement in performance and efficiency over existing methods, on both cardiac MRI and out-of-distribution medical imaging datasets. The code is available at https://github.com/bangwayne/Verse.
Semantic segmentation requires labour-intensive labelling tasks to obtain the supervision signals, and because of this issue, it is encouraged that using domain adaptation, which transfers information from the existing labelled source domains to unlabelled or weakly labelled target domains, is essential. However, it is intractable to find a well-generalised representation which can describe two domains due to probabilistic or geometric difference between the two domains. This paper presents a novel method, the Conditional and Inter-coder Connected Latent Diffusion (CICLD) based Semantic Segmentation Model, to advance unsupervised domain adaptation (UDA) for semantic segmentation tasks. Leveraging the strengths of latent diffusion models and adversarial learning, our method effectively bridges the gap between synthetic and real-world imagery. CICLD incorporates a conditioning mechanism to improve contextual understanding during segmentation and an inter-coder connection to preserve fine-grained details and spatial hierarchies. Additionally, adversarial learning aligns latent feature distributions across source, mixed, and target domains, further enhancing generalisation. Extensive experiments are conducted across three benchmark datasets-GTA5, Synthia, and Cityscape-shows that CICLD outperforms state-of-the-art UDA methods. Notably, the proposed method achieves a mean Intersection over Union (mIoU) of 74.4 for the GTA5 to Cityscape UDA setting and 67.2 mIoU for the Synthia to Cityscape UDA setting. This project is publicly available on 'https://github.com/andreYoo/CICLD'.
Natural Language Processing (NLP) is widely used in fields like machine translation and sentiment analysis. However, traditional NLP models struggle with accuracy and efficiency. This paper introduces Deep Convolutional Neural Networks (DCNN) into NLP to address these issues. By integrating DCNN, machine learning (ML) algorithms, and generative adversarial networks (GAN), the study improves language understanding, reduces ambiguity, and enhances task performance. The high-performance NLP model shows a 10% improvement in segmentation accuracy and a 4% increase in recall rate compared to traditional models. This integrated approach excels in tasks such as word segmentation, part-of-speech tagging, machine translation, and text classification, offering better recognition accuracy and processing efficiency.
Although semi-supervised learning has made significant advances in the field of medical image segmentation, fully annotating a volumetric sample slice by slice remains a costly and time-consuming task. Even worse, most of the existing approaches pay much attention to image-level information and ignore semantic features, resulting in the inability to perceive weak boundaries. To address these issues, we propose a novel Semantic-Guided Triplet Co-training (SGTC) framework, which achieves high-end medical image segmentation by only annotating three orthogonal slices of a few volumetric samples, significantly alleviating the burden of radiologists. Our method consist of two main components. Specifically, to enable semantic-aware, fine-granular segmentation and enhance the quality of pseudo-labels, a novel semantic-guided auxiliary learning mechanism is proposed based on the pretrained CLIP. In addition, focusing on a more challenging but clinically realistic scenario, a new triple-view disparity training strategy is proposed, which uses sparse annotations (i.e., only three labeled slices of a few volumes) to perform co-training between three sub-networks, significantly improving the robustness. Extensive experiments on three public medical datasets demonstrate that our method outperforms most state-of-the-art semi-supervised counterparts under sparse annotation settings. The source code is available at https://github.com/xmeimeimei/SGTC.
Histopathology, the microscopic examination of tissue samples, is essential for disease diagnosis and prognosis. Accurate segmentation and identification of key regions in histopathology images are crucial for developing automated solutions. However, state-of-art deep learning segmentation methods like UNet require extensive labels, which is both costly and time-consuming, particularly when dealing with multiple stainings. To mitigate this, multi-stain segmentation methods such as MDS1 and UDAGAN have been developed, which reduce the need for labels by requiring only one (source) stain to be labelled. Nonetheless, obtaining source stain labels can still be challenging, and segmentation models fail when they are unavailable. This article shows that through self-supervised pre-training, including SimCLR, BYOL, and a novel approach, HR-CS-CO, the performance of these segmentation methods (UNet, MDS1, and UDAGAN) can be retained even with 95% fewer labels. Notably, with self-supervised pre-training and using only 5% labels, the performance drops are minimal: 5.9% for UNet, 4.5% for MDS1, and 6.2% for UDAGAN, compared to their respective fully supervised counterparts (without pre-training, using 100% labels). The code is available from https://github.com/zeeshannisar/improve_kidney_glomeruli_segmentation [to be made public upon acceptance].
This work proposes a novel framework, Uncertainty-Guided Cross Attention Ensemble Mean Teacher (UG-CEMT), for achieving state-of-the-art performance in semi-supervised medical image segmentation. UG-CEMT leverages the strengths of co-training and knowledge distillation by combining a Cross-attention Ensemble Mean Teacher framework (CEMT) inspired by Vision Transformers (ViT) with uncertainty-guided consistency regularization and Sharpness-Aware Minimization emphasizing uncertainty. UG-CEMT improves semi-supervised performance while maintaining a consistent network architecture and task setting by fostering high disparity between sub-networks. Experiments demonstrate significant advantages over existing methods like Mean Teacher and Cross-pseudo Supervision in terms of disparity, domain generalization, and medical image segmentation performance. UG-CEMT achieves state-of-the-art results on multi-center prostate MRI and cardiac MRI datasets, where object segmentation is particularly challenging. Our results show that using only 10\% labeled data, UG-CEMT approaches the performance of fully supervised methods, demonstrating its effectiveness in exploiting unlabeled data for robust medical image segmentation. The code is publicly available at \url{https://github.com/Meghnak13/UG-CEMT}
Crack segmentation plays a crucial role in ensuring the structural integrity and seismic safety of civil structures. However, existing crack segmentation algorithms encounter challenges in maintaining accuracy with domain shifts across datasets. To address this issue, we propose a novel deep network that employs incremental training with unsupervised domain adaptation (UDA) using adversarial learning, without a significant drop in accuracy in the source domain. Our approach leverages an encoder-decoder architecture, consisting of both domain-invariant and domain-specific parameters. The encoder learns shared crack features across all domains, ensuring robustness to domain variations. Simultaneously, the decoder's domain-specific parameters capture domain-specific features unique to each domain. By combining these components, our model achieves improved crack segmentation performance. Furthermore, we introduce BuildCrack, a new crack dataset comparable to sub-datasets of the well-established CrackSeg9K dataset in terms of image count and crack percentage. We evaluate our proposed approach against state-of-the-art UDA methods using different sub-datasets of CrackSeg9K and our custom dataset. Our experimental results demonstrate a significant improvement in crack segmentation accuracy and generalization across target domains compared to other UDA methods - specifically, an improvement of 0.65 and 2.7 mIoU on source and target domains respectively.
Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical practice. In this work, we organized the first international competition dedicated to promptable medical image segmentation, featuring a large-scale dataset spanning nine common imaging modalities from over 20 different institutions. The top teams developed lightweight segmentation foundation models and implemented an efficient inference pipeline that substantially reduced computational requirements while maintaining state-of-the-art segmentation accuracy. Moreover, the post-challenge phase advanced the algorithms through the design of performance booster and reproducibility tasks, resulting in improved algorithms and validated reproducibility of the winning solution. Furthermore, the best-performing algorithms have been incorporated into the open-source software with a user-friendly interface to facilitate clinical adoption. The data and code are publicly available to foster the further development of medical image segmentation foundation models and pave the way for impactful real-world applications.
The accurate segmentation of guidewires in interventional cardiac fluoroscopy videos is crucial for computer-aided navigation tasks. Although deep learning methods have demonstrated high accuracy and robustness in wire segmentation, they require substantial annotated datasets for generalizability, underscoring the need for extensive labeled data to enhance model performance. To address this challenge, we propose the Segmentation-guided Frame-consistency Video Diffusion Model (SF-VD) to generate large collections of labeled fluoroscopy videos, augmenting the training data for wire segmentation networks. SF-VD leverages videos with limited annotations by independently modeling scene distribution and motion distribution. It first samples the scene distribution by generating 2D fluoroscopy images with wires positioned according to a specified input mask, and then samples the motion distribution by progressively generating subsequent frames, ensuring frame-to-frame coherence through a frame-consistency strategy. A segmentation-guided mechanism further refines the process by adjusting wire contrast, ensuring a diverse range of visibility in the synthesized image. Evaluation on a fluoroscopy dataset confirms the superior quality of the generated videos and shows significant improvements in guidewire segmentation.
The MitraClip is the most widely percutaneous treatment for mitral regurgitation, typically performed under the real-time guidance of 3D transesophagel echocardiography (TEE). However, artifacts and low image contrast in echocardiography hinder accurate clip visualization. This study presents an automated pipeline for clip detection from 3D TEE images. An Attention UNet was employed to segment the device, while a DenseNet classifier predicted its configuration among ten possible states, ranging from fully closed to fully open. Based on the predicted configuration, a template model derived from computer-aided design (CAD) was automatically registered to refine the segmentation and enable quantitative characterization of the device. The pipeline was trained and validated on 196 3D TEE images acquired using a heart simulator, with ground-truth annotations refined through CAD-based templates. The Attention UNet achieved an average surface distance of 0.76 mm and 95% Hausdorff distance of 2.44 mm for segmentation, while the DenseNet achieved an average weighted F1-score of 0.75 for classification. Post-refinement, segmentation accuracy improved, with average surface distance and 95% Hausdorff distance reduced to 0.75 mm and 2.05 mm, respectively. This pipeline enhanced clip visualization, providing fast and accurate detection with quantitative feedback, potentially improving procedural efficiency and reducing adverse outcomes.
Although multiview fusion has demonstrated potential in LiDAR segmentation, its dependence on computationally intensive point-based interactions, arising from the lack of fixed correspondences between views such as range view and Bird's-Eye View (BEV), hinders its practical deployment. This paper challenges the prevailing notion that multiview fusion is essential for achieving high performance. We demonstrate that significant gains can be realized by directly fusing Polar and Cartesian partitioning strategies within the BEV space. Our proposed BEV-only segmentation model leverages the inherent fixed grid correspondences between these partitioning schemes, enabling a fusion process that is orders of magnitude faster (170$\times$ speedup) than conventional point-based methods. Furthermore, our approach facilitates dense feature fusion, preserving richer contextual information compared to sparse point-based alternatives. To enhance scene understanding while maintaining inference efficiency, we also introduce a hybrid Transformer-CNN architecture. Extensive evaluation on the SemanticKITTI and nuScenes datasets provides compelling evidence that our method outperforms previous multiview fusion approaches in terms of both performance and inference speed, highlighting the potential of BEV-based fusion for LiDAR segmentation. Code is available at \url{https://github.com/skyshoumeng/PC-BEV.}