Raman scattering is based on molecular vibration spectroscopy and provides a powerful technology for pathogenic bacteria diagnosis using the unique molecular fingerprint information of a substance. The integration of deep learning technology has significantly improved the efficiency and accuracy of intelligent Raman spectroscopy (RS) recognition. However, the current RS recognition methods based on deep neural networks still require the annotation of a large amount of spectral data, which is labor-intensive. This paper presents a novel annotation-efficient Self-Calibrated Dual Contrasting (SCDC) method for RS recognition that operates effectively with few or no annotation. Our core motivation is to represent the spectrum from two different perspectives in two distinct subspaces: embedding and category. The embedding perspective captures instance-level information, while the category perspective reflects category-level information. Accordingly, we have implemented a dual contrastive learning approach from two perspectives to obtain discriminative representations, which are applicable for Raman spectroscopy recognition under both unsupervised and semi-supervised learning conditions. Furthermore, a self-calibration mechanism is proposed to enhance robustness. Validation of the identification task on three large-scale bacterial Raman spectroscopy datasets demonstrates that our SCDC method achieves robust recognition performance with very few (5$\%$ or 10$\%$) or no annotations, highlighting the potential of the proposed method for biospectral identification in annotation-efficient clinical scenarios.
In medical image analysis, multi-organ semi-supervised segmentation faces challenges such as insufficient labels and low contrast in soft tissues. To address these issues, existing studies typically employ semi-supervised segmentation techniques using pseudo-labeling and consistency regularization. However, these methods mainly rely on individual data samples for training, ignoring the rich neighborhood information present in the feature space. In this work, we argue that supervisory information can be directly extracted from the geometry of the feature space. Inspired by the density-based clustering hypothesis, we propose using feature density to locate sparse regions within feature clusters. Our goal is to increase intra-class compactness by addressing sparsity issues. To achieve this, we propose a Density-Aware Contrastive Learning (DACL) strategy, pushing anchored features in sparse regions towards cluster centers approximated by high-density positive samples, resulting in more compact clusters. Specifically, our method constructs density-aware neighbor graphs using labeled and unlabeled data samples to estimate feature density and locate sparse regions. We also combine label-guided co-training with density-guided geometric regularization to form complementary supervision for unlabeled data. Experiments on the Multi-Organ Segmentation Challenge dataset demonstrate that our proposed method outperforms state-of-the-art methods, highlighting its efficacy in medical image segmentation tasks.
Multimodal representation learning, with contrastive learning, plays an important role in the artificial intelligence domain. As an important subfield, video-language representation learning focuses on learning representations using global semantic interactions between pre-defined video-text pairs. However, to enhance and refine such coarse-grained global interactions, more detailed interactions are necessary for fine-grained multimodal learning. In this study, we introduce a new approach that models video-text as game players using multivariate cooperative game theory to handle uncertainty during fine-grained semantic interactions with diverse granularity, flexible combination, and vague intensity. Specifically, we design the Hierarchical Banzhaf Interaction to simulate the fine-grained correspondence between video clips and textual words from hierarchical perspectives. Furthermore, to mitigate the bias in calculations within Banzhaf Interaction, we propose reconstructing the representation through a fusion of single-modal and cross-modal components. This reconstructed representation ensures fine granularity comparable to that of the single-modal representation, while also preserving the adaptive encoding characteristics of cross-modal representation. Additionally, we extend our original structure into a flexible encoder-decoder framework, enabling the model to adapt to various downstream tasks. Extensive experiments on commonly used text-video retrieval, video-question answering, and video captioning benchmarks, with superior performance, validate the effectiveness and generalization of our method.
Weakly Supervised Monitoring Anomaly Detection (WSMAD) utilizes weak supervision learning to identify anomalies, a critical task for smart city monitoring. However, existing multimodal approaches often fail to meet the real-time and interpretability requirements of edge devices due to their complexity. This paper presents TCVADS (Two-stage Cross-modal Video Anomaly Detection System), which leverages knowledge distillation and cross-modal contrastive learning to enable efficient, accurate, and interpretable anomaly detection on edge devices.TCVADS operates in two stages: coarse-grained rapid classification and fine-grained detailed analysis. In the first stage, TCVADS extracts features from video frames and inputs them into a time series analysis module, which acts as the teacher model. Insights are then transferred via knowledge distillation to a simplified convolutional network (student model) for binary classification. Upon detecting an anomaly, the second stage is triggered, employing a fine-grained multi-class classification model. This stage uses CLIP for cross-modal contrastive learning with text and images, enhancing interpretability and achieving refined classification through specially designed triplet textual relationships. Experimental results demonstrate that TCVADS significantly outperforms existing methods in model performance, detection efficiency, and interpretability, offering valuable contributions to smart city monitoring applications.
Learning representations for multimedia content is critical for multimedia recommendation. Current representation learning methods roughly fall into two groups: (1) using the historical interactions to create ID embeddings of users and items, and (2) treating multi-modal data as the side information of items to enrich their ID embeddings. Each user-item interaction offers the supervisory signal to optimize the representation learning by the traditional supervised learning paradigm. Due to the overlook of the multi-modal patterns ( e.g. , co-occurrence of visual, acoustic, textual features in micro-videos a user saw before, and her behavioral features) hidden in the data, these methods are insufficient to create powerful representations and obtain satisfactory recommendation accuracy. To capture multi-modal patterns in the data itself, we go beyond the supervised learning paradigm, and incorporate the idea of self-supervised learning (SSL) into multimedia recommendation. Specifically, SSL consists of two components: (1) data augmentation upon multi-modal contents, where we design three operators — feature dropout (FD), feature masking (FM), feature fine and coarse spaces (FAC) — to generate multiple views of individual items; and (2) contrastive learning, which differentiates the views of an item from the others’ to distill additional supervisory signals. Clearly, SSL enables us to explore and exhibit the underlying relations among modalities, thereby resulting in powerful representations. We denote the generic framework by Self-supervised Learning-guided Multimedia Recommendation (SLMRec). Extensive experiments are performed on three real-world datasets, showing that SLMRec achieves significant improvements over several state-of-the-art baselines like LightGCN [1], MMGCN [2]. Further analysis shows how SSL affects recommendation performance.
Contrastive learning underpins most current self-supervised time series representation methods. The strategy for constructing positive and negative sample pairs significantly affects the final representation quality. However, due to the continuous nature of time series semantics, the modeling approach of contrastive learning struggles to accommodate the characteristics of time series data. This results in issues such as difficulties in constructing hard negative samples and the potential introduction of inappropriate biases during positive sample construction. Although some recent works have developed several scientific strategies for constructing positive and negative sample pairs with improved effectiveness, they remain constrained by the contrastive learning framework. To fundamentally overcome the limitations of contrastive learning, this paper introduces Frequency-masked Embedding Inference (FEI), a novel non-contrastive method that completely eliminates the need for positive and negative samples. The proposed FEI constructs 2 inference branches based on a prompting strategy: 1) Using frequency masking as prompts to infer the embedding representation of the target series with missing frequency bands in the embedding space, and 2) Using the target series as prompts to infer its frequency masking embedding. In this way, FEI enables continuous semantic relationship modeling for time series. Experiments on 8 widely used time series datasets for classification and regression tasks, using linear evaluation and end-to-end fine-tuning, show that FEI significantly outperforms existing contrastive-based methods in terms of generalization. This study provides new insights into self-supervised representation learning for time series. The code is available at https://github.com/USTBInnovationPark/Frequency-masked-Embedding-Inference.
With the rapid development of online social networks and the inadequacies in content moderation mechanisms, the detection of fake news has emerged as a pressing concern for the public. Various methods have been proposed for fake news detection, including text-based approaches as well as a series of graph-based approaches. However, the deceptive nature of fake news renders text-based approaches less effective. Propagation tree-based methods focus on the propagation process of individual news, capturing pairwise relationships but lacking the capability to capture high-order complex relationships. Large heterogeneous graph-based approaches necessitate the incorporation of substantial additional information beyond news text and user data, while hypergraph-based approaches rely on predefined hypergraph structures. To tackle these issues, we propose a novel dynamic hypergraph-based multi-view fake news detection model (DHy-MFND) that learns news embeddings across three distinct views: text-level, propagation tree-level, and hypergraph-level. By employing hypergraph structures to model complex high-order relationships among multiple news pieces and introducing dynamic hypergraph structure learning, we optimize predefined hypergraph structures while learning news embeddings. Additionally, we introduce contrastive learning to capture authenticity-relevant embeddings across different views. Extensive experiments on two benchmark datasets demonstrate the effectiveness of our proposed DHy-MFND compared with a broad range of competing baselines.
Unsupervised learning visible-infrared person re-identification (USL-VI-ReID) aims to learn modality-invariant features from unlabeled cross-modality datasets and reduce the inter-modality gap. However, the existing methods lack cross-modality clustering or excessively pursue cluster-level association, which makes it difficult to perform reliable modality-invariant features learning. To deal with this issue, we propose a Extended Cross-Modality United Learning (ECUL) framework, incorporating Extended Modality-Camera Clustering (EMCC) and Two-Step Memory Updating Strategy (TSMem) modules. Specifically, we design ECUL to naturally integrates intra-modality clustering, inter-modality clustering and inter-modality instance selection, establishing compact and accurate cross-modality associations while reducing the introduction of noisy labels. Moreover, EMCC captures and filters the neighborhood relationships by extending the encoding vector, which further promotes the learning of modality-invariant and camera-invariant knowledge in terms of clustering algorithm. Finally, TSMem provides accurate and generalized proxy points for contrastive learning by updating the memory in stages. Extensive experiments results on SYSU-MM01 and RegDB datasets demonstrate that the proposed ECUL shows promising performance and even outperforms certain supervised methods.
Generative AI has transformed the animation industry. Several models have been developed for image-to-image translation, particularly focusing on converting real-world images into anime through unpaired translation. Scenimefy, a notable approach utilizing contrastive learning, achieves high fidelity anime scene translation by addressing limited paired data through semi-supervised training. However, it faces limitations due to its reliance on paired data from a fine-tuned StyleGAN in the anime domain, often producing low-quality datasets. Additionally, Scenimefy's high parameter architecture presents opportunities for computational optimization. This research introduces NijiGAN, a novel model incorporating Neural Ordinary Differential Equations (NeuralODEs), which offer unique advantages in continuous transformation modeling compared to traditional residual networks. NijiGAN successfully transforms real-world scenes into high fidelity anime visuals using half of Scenimefy's parameters. It employs pseudo-paired data generated through Scenimefy for supervised training, eliminating dependence on low-quality paired data and improving the training process. Our comprehensive evaluation includes ablation studies, qualitative, and quantitative analysis comparing NijiGAN to similar models. The testing results demonstrate that NijiGAN produces higher-quality images compared to AnimeGAN, as evidenced by a Mean Opinion Score (MOS) of 2.192, it surpasses AnimeGAN's MOS of 2.160. Furthermore, our model achieved a Frechet Inception Distance (FID) score of 58.71, outperforming Scenimefy's FID score of 60.32. These results demonstrate that NijiGAN achieves competitive performance against existing state-of-the-arts, especially Scenimefy as the baseline model.
Conversational Speech Synthesis (CSS) aims to effectively take the multimodal dialogue history (MDH) to generate speech with appropriate conversational prosody for target utterance. The key challenge of CSS is to model the interaction between the MDH and the target utterance. Note that text and speech modalities in MDH have their own unique influences, and they complement each other to produce a comprehensive impact on the target utterance. Previous works did not explicitly model such intra-modal and inter-modal interactions. To address this issue, we propose a new intra-modal and inter-modal context interaction scheme-based CSS system, termed III-CSS. Specifically, in the training phase, we combine the MDH with the text and speech modalities in the target utterance to obtain four modal combinations, including Historical Text-Next Text, Historical Speech-Next Speech, Historical Text-Next Speech, and Historical Speech-Next Text. Then, we design two contrastive learning-based intra-modal and two inter-modal interaction modules to deeply learn the intra-modal and inter-modal context interaction. In the inference phase, we take MDH and adopt trained interaction modules to fully infer the speech prosody of the target utterance's text content. Subjective and objective experiments on the DailyTalk dataset show that III-CSS outperforms the advanced baselines in terms of prosody expressiveness. Code and speech samples are available at https://github.com/AI-S2-Lab/I3CSS.
Adversarial attacks exploit the vulnerabilities of convolutional neural networks by introducing imperceptible perturbations that lead to misclassifications, exposing weaknesses in feature representations and decision boundaries. This paper presents a novel framework combining supervised contrastive learning and margin-based contrastive loss to enhance adversarial robustness. Supervised contrastive learning improves the structure of the feature space by clustering embeddings of samples within the same class and separating those from different classes. Margin-based contrastive loss, inspired by support vector machines, enforces explicit constraints to create robust decision boundaries with well-defined margins. Experiments on the CIFAR-100 dataset with a ResNet-18 backbone demonstrate robustness performance improvements in adversarial accuracy under Fast Gradient Sign Method attacks.
Graph Neural Networks (GNNs) have recently gained widespread attention as a successful tool for analyzing graph-structured data. However, imperfect graph structure with noisy links lacks enough robustness and may damage graph representations, therefore limiting the GNNs' performance in practical tasks. Moreover, existing generative architectures fail to fit discriminative graph-related tasks. To tackle these issues, we introduce an unsupervised method based on a joint of generative training and discriminative training to learn graph structure and representation, aiming to improve the discriminative performance of generative models. We propose an Energy-based Contrastive Learning (ECL) guided Graph Structure Refinement (GSR) framework, denoted as ECL-GSR. To our knowledge, this is the first work to combine energy-based models with contrastive learning for GSR. Specifically, we leverage ECL to approximate the joint distribution of sample pairs, which increases the similarity between representations of positive pairs while reducing the similarity between negative ones. Refined structure is produced by augmenting and removing edges according to the similarity metrics among node representations. Extensive experiments demonstrate that ECL-GSR outperforms the state-of-the-art on eight benchmark datasets in node classification. ECL-GSR achieves faster training with fewer samples and memories against the leading baseline, highlighting its simplicity and efficiency in downstream tasks.
Interactive Recommendation (IR) has gained significant attention recently for its capability to quickly capture dynamic interest and optimize both short and long term objectives. IR agents are typically implemented through Deep Reinforcement Learning (DRL), because DRL is inherently compatible with the dynamic nature of IR. However, DRL is currently not perfect for IR. Due to the large action space and sample inefficiency problem, training DRL recommender agents is challenging. The key point is that useful features cannot be extracted as high-quality representations for the recommender agent to optimize its policy. To tackle this problem, we propose Contrastive Representation for Interactive Recommendation (CRIR). CRIR efficiently extracts latent, high-level preference ranking features from explicit interaction, and leverages the features to enhance users' representation. Specifically, the CRIR provides representation through one representation network, and refines it through our proposed Preference Ranking Contrastive Learning (PRCL). The key insight of PRCL is that it can perform contrastive learning without relying on computations involving high-level representations or large potential action sets. Furthermore, we also propose a data exploiting mechanism and an agent training mechanism to better adapt CRIR to the DRL backbone. Extensive experiments have been carried out to show our method's superior improvement on the sample efficiency while training an DRL-based IR agent.
Federated learning has become a promising solution for collaboration among medical institutions. However, data owned by each institution would be highly heterogeneous and the distribution is always non-independent and identical distribution (non-IID), resulting in client drift and unsatisfactory performance. Despite existing federated learning methods attempting to solve the non-IID problems, they still show marginal advantages but rely on frequent communication which would incur high costs and privacy concerns. In this paper, we propose a novel federated learning method: \textbf{Fed}erated learning via \textbf{V}aluable \textbf{C}ondensed \textbf{K}nowledge (FedVCK). We enhance the quality of condensed knowledge and select the most necessary knowledge guided by models, to tackle the non-IID problem within limited communication budgets effectively. Specifically, on the client side, we condense the knowledge of each client into a small dataset and further enhance the condensation procedure with latent distribution constraints, facilitating the effective capture of high-quality knowledge. During each round, we specifically target and condense knowledge that has not been assimilated by the current model, thereby preventing unnecessary repetition of homogeneous knowledge and minimizing the frequency of communications required. On the server side, we propose relational supervised contrastive learning to provide more supervision signals to aid the global model updating. Comprehensive experiments across various medical tasks show that FedVCK can outperform state-of-the-art methods, demonstrating that it's non-IID robust and communication-efficient.
Tumor synthesis can generate examples that AI often misses or over-detects, improving AI performance by training on these challenging cases. However, existing synthesis methods, which are typically unconditional -- generating images from random variables -- or conditioned only by tumor shapes, lack controllability over specific tumor characteristics such as texture, heterogeneity, boundaries, and pathology type. As a result, the generated tumors may be overly similar or duplicates of existing training data, failing to effectively address AI's weaknesses. We propose a new text-driven tumor synthesis approach, termed TextoMorph, that provides textual control over tumor characteristics. This is particularly beneficial for examples that confuse the AI the most, such as early tumor detection (increasing Sensitivity by +8.5%), tumor segmentation for precise radiotherapy (increasing DSC by +6.3%), and classification between benign and malignant tumors (improving Sensitivity by +8.2%). By incorporating text mined from radiology reports into the synthesis process, we increase the variability and controllability of the synthetic tumors to target AI's failure cases more precisely. Moreover, TextoMorph uses contrastive learning across different texts and CT scans, significantly reducing dependence on scarce image-report pairs (only 141 pairs used in this study) by leveraging a large corpus of 34,035 radiology reports. Finally, we have developed rigorous tests to evaluate synthetic tumors, including Text-Driven Visual Turing Test and Radiomics Pattern Analysis, showing that our synthetic tumors is realistic and diverse in texture, heterogeneity, boundaries, and pathology.
We introduce a new task called Defeasible Visual Entailment (DVE), where the goal is to allow the modification of the entailment relationship between an image premise and a text hypothesis based on an additional update. While this concept is well-established in Natural Language Inference, it remains unexplored in visual entailment. At a high level, DVE enables models to refine their initial interpretations, leading to improved accuracy and reliability in various applications such as detecting misleading information in images, enhancing visual question answering, and refining decision-making processes in autonomous systems. Existing metrics do not adequately capture the change in the entailment relationship brought by updates. To address this, we propose a novel inference-aware evaluator designed to capture changes in entailment strength induced by updates, using pairwise contrastive learning and categorical information learning. Additionally, we introduce a reward-driven update optimization method to further enhance the quality of updates generated by multimodal models. Experimental results demonstrate the effectiveness of our proposed evaluator and optimization method.
Graph contrastive learning (GCL) has become a hot topic in the field of graph representation learning. In contrast to traditional supervised learning relying on a large number of labels, GCL exploits augmentation strategies to generate multiple views and positive/negative pairs, both of which greatly influence the performance. Unfortunately, commonly used random augmentations may disturb the underlying semantics of graphs. Moreover, traditional GNNs, a type of widely employed encoders in GCL, are inevitably confronted with over-smoothing and over-squashing problems. To address these issues, we propose GNN-Transformer Cooperative Architecture for Trustworthy Graph Contrastive Learning (GTCA), which inherits the advantages of both GNN and Transformer, incorporating graph topology to obtain comprehensive graph representations. Theoretical analysis verifies the trustworthiness of the proposed method. Extensive experiments on benchmark datasets demonstrate state-of-the-art empirical performance.
While Natural Language Inference (NLI) models have achieved high performances on benchmark datasets, there are still concerns whether they truly capture the intended task, or largely exploit dataset artifacts. Through detailed analysis of the Stanford Natural Language Inference (SNLI) dataset, we have uncovered complex patterns of various types of artifacts and their interactions, leading to the development of our novel structural debiasing approach. Our fine-grained analysis of 9,782 validation examples reveals four major categories of artifacts: length-based patterns, lexical overlap, subset relationships, and negation patterns. Our multi-head debiasing architecture achieves substantial improvements across all bias categories: length bias accuracy improved from 86.03% to 90.06%, overlap bias from 91.88% to 93.13%, subset bias from 95.43% to 96.49%, and negation bias from 88.69% to 94.64%. Overall, our approach reduces the error rate from 14.19% to 10.42% while maintaining high performance on unbiased examples. Analysis of 1,026 error cases shows significant improvement in handling neutral relationships, traditionally one of the most challenging areas for NLI systems.
Classifying antimicrobial peptides(AMPs) from the vast array of peptides mined from metagenomic sequencing data is a significant approach to addressing the issue of antibiotic resistance. However, current AMP classification methods, primarily relying on sequence-based data, neglect the spatial structure of peptides, thereby limiting the accurate classification of AMPs. Additionally, the number of known AMPs is significantly lower than that of non-AMPs, leading to imbalanced datasets that reduce predictive accuracy for AMPs. To alleviate these two limitations, we first employ Omegafold to predict the three-dimensional spatial structures of AMPs and non-AMPs, constructing peptide graphs based on the amino acids' C$_\alpha$ positions. Building upon this, we propose a novel classification model named Spatial GNN-based AMP Classifier (SGAC). Our SGAC model employs a graph encoder based on Graph Neural Networks (GNNs) to process peptide graphs, generating high-dimensional representations that capture essential features from the three-dimensional spatial structure of amino acids. Then, to address the inherent imbalanced datasets, SGAC first incorporates Weight-enhanced Contrastive Learning, which clusters similar peptides while ensuring separation between dissimilar ones, using weighted contributions to emphasize AMP-specific features. Furthermore, SGAC employs Weight-enhanced Pseudo-label Distillation to dynamically generate high-confidence pseudo labels for ambiguous peptides, further refining predictions and promoting balanced learning between AMPs and non-AMPs. Experiments on publicly available AMP and non-AMP datasets demonstrate that SGAC significantly outperforms traditional sequence-based methods and achieves state-of-the-art performance among graph-based models, validating its effectiveness in AMP classification.
This paper introduces a novel synthetic dataset that captures urban scenes under a variety of weather conditions, providing pixel-perfect, ground-truth-aligned images to facilitate effective feature alignment across domains. Additionally, we propose a method for domain adaptation and generalization that takes advantage of the multiple versions of each scene, enforcing feature consistency across different weather scenarios. Our experimental results demonstrate the impact of our dataset in improving performance across several alignment metrics, addressing key challenges in domain adaptation and generalization for segmentation tasks. This research also explores critical aspects of synthetic data generation, such as optimizing the balance between the volume and variability of generated images to enhance segmentation performance. Ultimately, this work sets forth a new paradigm for synthetic data generation and domain adaptation.