We apply active learning to help with data scarcity problems in sign languages. In particular, we perform a novel analysis of the effect of pre-training. Since many sign languages are linguistic descendants of French sign language, they share hand configurations, which pre-training can hopefully exploit. We test this hypothesis on American, Chinese, German, and Irish fingerspelling corpora. We do observe a benefit from pre-training, but this may be due to visual rather than linguistic similarities
Virtual screening of large compound libraries to identify potential hit candidates is one of the earliest steps in drug discovery. As the size of commercially available compound collections grows exponentially to the scale of billions, brute-force virtual screening using traditional tools such as docking becomes infeasible in terms of time and computational resources. Active learning and Bayesian optimization has recently been proven as effective methods of narrowing down the search space. An essential component in those methods is a surrogate machine learning model that is trained with a small subset of the library to predict the desired properties of compounds. Accurate model can achieve high sample efficiency by finding the most promising compounds with only a fraction of the whole library being virtually screened. In this study, we examined the performance of pretrained transformer-based language model and graph neural network in Bayesian optimization active learning framework. The best pretrained models identifies 58.97% of the top-50000 by docking score after screening only 0.6% of an ultra-large library containing 99.5 million compounds, improving 8% over previous state-of-the-art baseline. Through extensive benchmarks, we show that the superior performance of pretrained models persists in both structure-based and ligand-based drug discovery. Such model can serve as a boost to the accuracy and sample efficiency of active learning based molecule virtual screening.
Active learning has been utilized as an efficient tool in building anomaly detection models by leveraging expert feedback. In an active learning framework, a model queries samples to be labeled by experts and re-trains the model with the labeled data samples. It unburdens in obtaining annotated datasets while improving anomaly detection performance. However, most of the existing studies focus on helping experts identify as many abnormal data samples as possible, which is a sub-optimal approach for one-class classification-based deep anomaly detection. In this paper, we tackle two essential problems of active learning for Deep SVDD: query strategy and semi-supervised learning method. First, rather than solely identifying anomalies, our query strategy selects uncertain samples according to an adaptive boundary. Second, we apply noise contrastive estimation in training a one-class classification model to incorporate both labeled normal and abnormal data effectively. We analyze that the proposed query strategy and semi-supervised loss individually improve an active learning process of anomaly detection and further improve when combined together on seven anomaly detection datasets.
Developing personalised thermal comfort models to inform occupant-centric controls (OCC) in buildings requires collecting large amounts of real-time occupant preference data. This process can be highly intrusive and labour-intensive for large-scale implementations, limiting the practicality of real-world OCC implementations. To address this issue, this study proposes a thermal preference-based HVAC control framework enhanced with Active Learning (AL) to address the data challenges related to real-world implementations of such OCC systems. The proposed AL approach proactively identifies the most informative thermal conditions for human annotation and iteratively updates a supervised thermal comfort model. The resulting model is subsequently used to predict the occupants' thermal preferences under different thermal conditions, which are integrated into the building's HVAC controls. The feasibility of our proposed AL-enabled OCC was demonstrated in an EnergyPlus simulation of a real-world testbed supplemented with the thermal preference data of 58 study occupants. The preliminary results indicated a significant reduction in overall labelling effort (i.e., 31.0%) between our AL-enabled OCC and conventional OCC while still achieving a slight increase in energy savings (i.e., 1.3%) and thermal satisfaction levels above 98%. This result demonstrates the potential for deploying such systems in future real-world implementations, enabling personalised comfort and energy-efficient building operations.
The ability to retrieve a photo by mere free-hand sketching highlights the immense potential of Fine-grained sketch-based image retrieval (FG-SBIR). However, its rapid practical adoption, as well as scalability, is limited by the expense of acquiring faithful sketches for easily available photo counterparts. A solution to this problem is Active Learning, which could minimise the need for labeled sketches while maximising performance. Despite extensive studies in the field, there exists no work that utilises it for reducing sketching effort in FG-SBIR tasks. To this end, we propose a novel active learning sampling technique that drastically minimises the need for drawing photo sketches. Our proposed approach tackles the trade-off between uncertainty and diversity by utilising the relationship between the existing photo-sketch pair to a photo that does not have its sketch and augmenting this relation with its intermediate representations. Since our approach relies only on the underlying data distribution, it is agnostic of the modelling approach and hence is applicable to other cross-modal instance-level retrieval tasks as well. With experimentation over two publicly available fine-grained SBIR datasets ChairV2 and ShoeV2, we validate our approach and reveal its superiority over adapted baselines.
This paper proposes a new active learning method for semantic segmentation. The core of our method lies in a new annotation query design. It samples informative local image regions (e.g., superpixels), and for each of such regions, asks an oracle for a multi-hot vector indicating all classes existing in the region. This multi-class labeling strategy is substantially more efficient than existing ones like segmentation, polygon, and even dominant class labeling in terms of annotation time per click. However, it introduces the class ambiguity issue in training as it assigns partial labels (i.e., a set of candidate classes) to individual pixels. We thus propose a new algorithm for learning semantic segmentation while disambiguating the partial labels in two stages. In the first stage, it trains a segmentation model directly with the partial labels through two new loss functions motivated by partial label learning and multiple instance learning. In the second stage, it disambiguates the partial labels by generating pixel-wise pseudo labels, which are used for supervised learning of the model. Equipped with a new acquisition function dedicated to the multi-class labeling, our method outperforms previous work on Cityscapes and PASCAL VOC 2012 while spending less annotation cost. Our code and results are available at https://github.com/sehyun03/MulActSeg.
We study the problem of teaching via demonstrations in sequential decision-making tasks. In particular, we focus on the situation when the teacher has no access to the learner's model and policy, and the feedback from the learner is limited to trajectories that start from states selected by the teacher. The necessity to select the starting states and infer the learner's policy creates an opportunity for using the methods of inverse reinforcement learning and active learning by the teacher. In this work, we formalize the teaching process with limited feedback and propose an algorithm that solves this teaching problem. The algorithm uses a modified version of the active value-at-risk method to select the starting states, a modified maximum causal entropy algorithm to infer the policy, and the difficulty score ratio method to choose the teaching demonstrations. We test the algorithm in a synthetic car driving environment and conclude that the proposed algorithm is an effective solution when the learner's feedback is limited.
The rapidly evolving nature of Android apps poses a significant challenge to static batch machine learning algorithms employed in malware detection systems, as they quickly become obsolete. Despite this challenge, the existing literature pays limited attention to addressing this issue, with many advanced Android malware detection approaches, such as Drebin, DroidDet and MaMaDroid, relying on static models. In this work, we show how retraining techniques are able to maintain detector capabilities over time. Particularly, we analyze the effect of two aspects in the efficiency and performance of the detectors: 1) the frequency with which the models are retrained, and 2) the data used for retraining. In the first experiment, we compare periodic retraining with a more advanced concept drift detection method that triggers retraining only when necessary. In the second experiment, we analyze sampling methods to reduce the amount of data used to retrain models. Specifically, we compare fixed sized windows of recent data and state-of-the-art active learning methods that select those apps that help keep the training dataset small but diverse. Our experiments show that concept drift detection and sample selection mechanisms result in very efficient retraining strategies which can be successfully used to maintain the performance of the static Android malware state-of-the-art detectors in changing environments.
We are not only observers but also actors of reality. Our capability to intervene and alter the course of some events in the space and time surrounding us is an essential component of how we build our model of the world. In this doctoral thesis we introduce a generic a-priori assessment of each possible intervention, in order to select the most cost-effective interventions only, and avoid unnecessary systematic experimentation on the real world. Based on this a-priori assessment, we propose an active learning algorithm that identifies the causal relations in any given causal model, using a least cost sequence of interventions. There are several novel aspects introduced by our algorithm. It is, in most case scenarios, able to discard many causal model candidates using relatively inexpensive interventions that only test one value of the intervened variables. Also, the number of interventions performed by the algorithm can be bounded by the number of causal model candidates. Hence, fewer initial candidates (or equivalently, more prior knowledge) lead to fewer interventions for causal discovery. Causality is intimately related to time, as causes appear to precede their effects. Cyclical causal processes are a very interesting case of causality in relation to time. In this doctoral thesis we introduce a formal analysis of time cyclical causal settings by defining a causal analog to the purely observational Dynamic Bayesian Networks, and provide a sound and complete algorithm for the identification of causal effects in the cyclic setting. We introduce the existence of two types of hidden confounder variables in this framework, which affect in substantially different ways the identification procedures, a distinction with no analog in either Dynamic Bayesian Networks or standard causal graphs.
Object detection (OD), a crucial vision task, remains challenged by the lack of large training datasets with precise object localization labels. In this work, we propose ALWOD, a new framework that addresses this problem by fusing active learning (AL) with weakly and semi-supervised object detection paradigms. Because the performance of AL critically depends on the model initialization, we propose a new auxiliary image generator strategy that utilizes an extremely small labeled set, coupled with a large weakly tagged set of images, as a warm-start for AL. We then propose a new AL acquisition function, another critical factor in AL success, that leverages the student-teacher OD pair disagreement and uncertainty to effectively propose the most informative images to annotate. Finally, to complete the AL loop, we introduce a new labeling task delegated to human annotators, based on selection and correction of model-proposed detections, which is both rapid and effective in labeling the informative images. We demonstrate, across several challenging benchmarks, that ALWOD significantly narrows the gap between the ODs trained on few partially labeled but strategically selected image instances and those that rely on the fully-labeled data. Our code is publicly available on https://github.com/seqam-lab/ALWOD.
This thesis explores challenges in semantic parsing, specifically focusing on scenarios with limited data and computational resources. It offers solutions using techniques like automatic data curation, knowledge transfer, active learning, and continual learning. For tasks with no parallel training data, the thesis proposes generating synthetic training examples from structured database schemas. When there is abundant data in a source domain but limited parallel data in a target domain, knowledge from the source is leveraged to improve parsing in the target domain. For multilingual situations with limited data in the target languages, the thesis introduces a method to adapt parsers using a limited human translation budget. Active learning is applied to select source-language samples for manual translation, maximizing parser performance in the target language. In addition, an alternative method is also proposed to utilize machine translation services, supplemented by human-translated data, to train a more effective parser. When computational resources are limited, a continual learning approach is introduced to minimize training time and computational memory. This maintains the parser's efficiency in previously learned tasks while adapting it to new tasks, mitigating the problem of catastrophic forgetting. Overall, the thesis provides a comprehensive set of methods to improve semantic parsing in resource-constrained conditions.
A common bottleneck in deploying supervised learning systems is collecting human-annotated examples. In many domains, annotators form an opinion about the label of an example incrementally--e.g., each additional word read from a document or each additional minute spent inspecting a video helps inform the annotation. In this paper, we investigate whether we can train learning systems more efficiently by requesting an annotation before inspection is fully complete--e.g., after reading only 25 words of a document. While doing so may reduce the overall annotation time, it also introduces the risk that the annotator might not be able to provide a label if interrupted too early. We propose an anytime active learning approach that optimizes the annotation time and response rate simultaneously. We conduct user studies on two document classification datasets and develop simulated annotators that mimic the users. Our simulated experiments show that anytime active learning outperforms several baselines on these two datasets. For example, with an annotation budget of one hour, training a classifier by annotating the first 25 words of each document reduces classification error by 17% over annotating the first 100 words of each document.
Search methods based on Pretrained Language Models (PLM) have demonstrated great effectiveness gains compared to statistical and early neural ranking models. However, fine-tuning PLM-based rankers requires a great amount of annotated training data. Annotating data involves a large manual effort and thus is expensive, especially in domain specific tasks. In this paper we investigate fine-tuning PLM-based rankers under limited training data and budget. We investigate two scenarios: fine-tuning a ranker from scratch, and domain adaptation starting with a ranker already fine-tuned on general data, and continuing fine-tuning on a target dataset. We observe a great variability in effectiveness when fine-tuning on different randomly selected subsets of training data. This suggests that it is possible to achieve effectiveness gains by actively selecting a subset of the training data that has the most positive effect on the rankers. This way, it would be possible to fine-tune effective PLM rankers at a reduced annotation budget. To investigate this, we adapt existing Active Learning (AL) strategies to the task of fine-tuning PLM rankers and investigate their effectiveness, also considering annotation and computational costs. Our extensive analysis shows that AL strategies do not significantly outperform random selection of training subsets in terms of effectiveness. We further find that gains provided by AL strategies come at the expense of more assessments (thus higher annotation costs) and AL strategies underperform random selection when comparing effectiveness given a fixed annotation cost. Our results highlight that ``optimal'' subsets of training data that provide high effectiveness at low annotation cost do exist, but current mainstream AL strategies applied to PLM rankers are not capable of identifying them.
Remote sensing through semantic segmentation of satellite images contributes to the understanding and utilisation of the earth's surface. For this purpose, semantic segmentation networks are typically trained on large sets of labelled satellite images. However, obtaining expert labels for these images is costly. Therefore, we propose to rely on a low-cost approach, e.g. crowdsourcing or pretrained networks, to label the images in the first step. Since these initial labels are partially erroneous, we use active learning strategies to cost-efficiently refine the labels in the second step. We evaluate the active learning strategies using satellite images of Bengaluru in India, labelled with land cover and land use labels. Our experimental results suggest that an active label refinement to improve the semantic segmentation network's performance is beneficial.
The incredible capabilities of generative artificial intelligence models have inevitably led to their application in the domain of drug discovery. Within this domain, the vastness of chemical space motivates the development of more efficient methods for identifying regions with molecules that exhibit desired characteristics. In this work, we present a computationally efficient active learning methodology that requires evaluation of only a subset of the generated data in the constructed sample space to successfully align a generative model with respect to a specified objective. We demonstrate the applicability of this methodology to targeted molecular generation by fine-tuning a GPT-based molecular generator toward a protein with FDA-approved small-molecule inhibitors, c-Abl kinase. Remarkably, the model learns to generate molecules similar to the inhibitors without prior knowledge of their existence, and even reproduces two of them exactly. We also show that the methodology is effective for a protein without any commercially available small-molecule inhibitors, the HNH domain of the CRISPR-associated protein 9 (Cas9) enzyme. We believe that the inherent generality of this method ensures that it will remain applicable as the exciting field of in silico molecular generation evolves. To facilitate implementation and reproducibility, we have made all of our software available through the open-source ChemSpaceAL Python package.
The retina is the only part of the human body in which blood vessels can be accessed non-invasively using imaging techniques such as digital fundus images (DFI). The spatial distribution of the retinal microvasculature may change with cardiovascular diseases and thus the eyes may be regarded as a window to our hearts. Computerized segmentation of the retinal arterioles and venules (A/V) is essential for automated microvasculature analysis. Using active learning, we created a new DFI dataset containing 240 crowd-sourced manual A/V segmentations performed by fifteen medical students and reviewed by an ophthalmologist, and developed LUNet, a novel deep learning architecture for high resolution A/V segmentation. LUNet architecture includes a double dilated convolutional block that aims to enhance the receptive field of the model and reduce its parameter count. Furthermore, LUNet has a long tail that operates at high resolution to refine the segmentation. The custom loss function emphasizes the continuity of the blood vessels. LUNet is shown to significantly outperform two state-of-the-art segmentation algorithms on the local test set as well as on four external test sets simulating distribution shifts across ethnicity, comorbidities, and annotators. We make the newly created dataset open access (upon publication).
Pool-based active learning (AL) is a promising technology for increasing data-efficiency of machine learning models. However, surveys show that performance of recent AL methods is very sensitive to the choice of dataset and training setting, making them unsuitable for general application. In order to tackle this problem, the field Learning Active Learning (LAL) suggests to learn the active learning strategy itself, allowing it to adapt to the given setting. In this work, we propose a novel LAL method for classification that exploits symmetry and independence properties of the active learning problem with an Attentive Conditional Neural Process model. Our approach is based on learning from a myopic oracle, which gives our model the ability to adapt to non-standard objectives, such as those that do not equally weight the error on all data points. We experimentally verify that our Neural Process model outperforms a variety of baselines in these settings. Finally, our experiments show that our model exhibits a tendency towards improved stability to changing datasets. However, performance is sensitive to choice of classifier and more work is necessary to reduce the performance the gap with the myopic oracle and to improve scalability. We present our work as a proof-of-concept for LAL on nonstandard objectives and hope our analysis and modelling considerations inspire future LAL work.
Active learning (AL) reduces the amount of labeled data needed to train a machine learning model by intelligently choosing which instances to label. Classic pool-based AL requires all data to be present in a datacenter, which can be challenging with the increasing amounts of data needed in deep learning. However, AL on mobile devices and robots, like autonomous cars, can filter the data from perception sensor streams before reaching the datacenter. We exploited the temporal properties for such image streams in our work and proposed the novel temporal predicted loss (TPL) method. To evaluate the stream-based setting properly, we introduced the GTA V streets and the A2D2 streets dataset and made both publicly available. Our experiments showed that our approach significantly improves the diversity of the selection while being an uncertainty-based method. As pool-based approaches are more common in perception applications, we derived a concept for comparing pool-based and stream-based AL, where TPL out-performed state-of-the-art pool- or stream-based approaches for different models. TPL demonstrated a gain of 2.5 precept points (pp) less required data while being significantly faster than pool-based methods.
Modern deep learning heavily relies on large labeled datasets, which often comse with high costs in terms of both manual labeling and computational resources. To mitigate these challenges, researchers have explored the use of informative subset selection techniques, including coreset selection and active learning. Specifically, coreset selection involves sampling data with both input ($\bx$) and output ($\by$), active learning focuses solely on the input data ($\bx$). In this study, we present a theoretically optimal solution for addressing both coreset selection and active learning within the context of linear softmax regression. Our proposed method, COPS (unCertainty based OPtimal Sub-sampling), is designed to minimize the expected loss of a model trained on subsampled data. Unlike existing approaches that rely on explicit calculations of the inverse covariance matrix, which are not easily applicable to deep learning scenarios, COPS leverages the model's logits to estimate the sampling ratio. This sampling ratio is closely associated with model uncertainty and can be effectively applied to deep learning tasks. Furthermore, we address the challenge of model sensitivity to misspecification by incorporating a down-weighting approach for low-density samples, drawing inspiration from previous works. To assess the effectiveness of our proposed method, we conducted extensive empirical experiments using deep neural networks on benchmark datasets. The results consistently showcase the superior performance of COPS compared to baseline methods, reaffirming its efficacy.
The Cancer Registry of Norway (CRN) collects information on cancer patients by receiving cancer messages from different medical entities (e.g., medical labs, and hospitals) in Norway. Such messages are validated by an automated cancer registry system: GURI. Its correct operation is crucial since it lays the foundation for cancer research and provides critical cancer-related statistics to its stakeholders. Constructing a cyber-cyber digital twin (CCDT) for GURI can facilitate various experiments and advanced analyses of the operational state of GURI without requiring intensive interactions with the real system. However, GURI constantly evolves due to novel medical diagnostics and treatment, technological advances, etc. Accordingly, CCDT should evolve as well to synchronize with GURI. A key challenge of achieving such synchronization is that evolving CCDT needs abundant data labelled by the new GURI. To tackle this challenge, we propose EvoCLINICAL, which considers the CCDT developed for the previous version of GURI as the pretrained model and fine-tunes it with the dataset labelled by querying a new GURI version. EvoCLINICAL employs a genetic algorithm to select an optimal subset of cancer messages from a candidate dataset and query GURI with it. We evaluate EvoCLINICAL on three evolution processes. The precision, recall, and F1 score are all greater than 91%, demonstrating the effectiveness of EvoCLINICAL. Furthermore, we replace the active learning part of EvoCLINICAL with random selection to study the contribution of transfer learning to the overall performance of EvoCLINICAL. Results show that employing active learning in EvoCLINICAL increases its performances consistently.