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arXiv:2407.02528

Actionable Cyber Threat Intelligence using Knowledge Graphs and Large Language Models

Cyber threats are constantly evolving. Extracting actionable insights from unstructured Cyber Threat Intelligence (CTI) data is essential to guide cybersecurity decisions. Increasingly, organizations like Microsoft, Trend Micro, and CrowdStrike are using generative AI to facilitate CTI extraction. This paper addresses the challenge of automating the extraction of actionable CTI using advancements in Large Language Models (LLMs) and Knowledge Graphs (KGs). We explore the application of state-of-the-art open-source LLMs, including the Llama 2 series, Mistral 7B Instruct, and Zephyr for extracting meaningful triples from CTI texts. Our methodology evaluates techniques such as prompt engineering, the guidance framework, and fine-tuning to optimize information extraction and structuring. The extracted data is then utilized to construct a KG, offering a structured and queryable representation of threat intelligence. Experimental results demonstrate the effectiveness of our approach in extracting relevant information, with guidance and fine-tuning showing superior performance over prompt engineering. However, while our methods prove effective in small-scale tests, applying LLMs to large-scale data for KG construction and Link Prediction presents ongoing challenges.

arXiv:2407.03004

SemioLLM: Assessing Large Language Models for Semiological Analysis in Epilepsy Research

Large Language Models have shown promising results in their ability to encode general medical knowledge in standard medical question-answering datasets. However, their potential application in clinical practice requires evaluation in domain-specific tasks, where benchmarks are largely missing. In this study semioLLM, we test the ability of state-of-the-art LLMs (GPT-3.5, GPT-4, Mixtral 8x7B, and Qwen-72chat) to leverage their internal knowledge and reasoning for epilepsy diagnosis. Specifically, we obtain likelihood estimates linking unstructured text descriptions of seizures to seizure-generating brain regions, using an annotated clinical database containing 1269 entries. We evaluate the LLM's performance, confidence, reasoning, and citation abilities in comparison to clinical evaluation. Models achieve above-chance classification performance with prompt engineering significantly improving their outcome, with some models achieving close-to-clinical performance and reasoning. However, our analyses also reveal significant pitfalls with several models being overly confident while showing poor performance, as well as exhibiting citation errors and hallucinations. In summary, our work provides the first extensive benchmark comparing current SOTA LLMs in the medical domain of epilepsy and highlights their ability to leverage unstructured texts from patients' medical history to aid diagnostic processes in health care.

arXiv:2407.01606공식 코드 · Papers with Code

On Discrete Prompt Optimization for Diffusion Models

This paper introduces the first gradient-based framework for prompt optimization in text-to-image diffusion models. We formulate prompt engineering as a discrete optimization problem over the language space. Two major challenges arise in efficiently finding a solution to this problem: (1) Enormous Domain Space: Setting the domain to the entire language space poses significant difficulty to the optimization process. (2) Text Gradient: Efficiently computing the text gradient is challenging, as it requires backpropagating through the inference steps of the diffusion model and a non-differentiable embedding lookup table. Beyond the problem formulation, our main technical contributions lie in solving the above challenges. First, we design a family of dynamically generated compact subspaces comprised of only the most relevant words to user input, substantially restricting the domain space. Second, we introduce "Shortcut Text Gradient" -- an effective replacement for the text gradient that can be obtained with constant memory and runtime. Empirical evaluation on prompts collected from diverse sources (DiffusionDB, ChatGPT, COCO) suggests that our method can discover prompts that substantially improve (prompt enhancement) or destroy (adversarial attack) the faithfulness of images generated by the text-to-image diffusion model.

arXiv:2407.01896공식 코드 · Papers with Code

LogEval: A Comprehensive Benchmark Suite for Large Language Models In Log Analysis

Log analysis is crucial for ensuring the orderly and stable operation of information systems, particularly in the field of Artificial Intelligence for IT Operations (AIOps). Large Language Models (LLMs) have demonstrated significant potential in natural language processing tasks. In the AIOps domain, they excel in tasks such as anomaly detection, root cause analysis of faults, operations and maintenance script generation, and alert information summarization. However, the performance of current LLMs in log analysis tasks remains inadequately validated. To address this gap, we introduce LogEval, a comprehensive benchmark suite designed to evaluate the capabilities of LLMs in various log analysis tasks for the first time. This benchmark covers tasks such as log parsing, log anomaly detection, log fault diagnosis, and log summarization. LogEval evaluates each task using 4,000 publicly available log data entries and employs 15 different prompts for each task to ensure a thorough and fair assessment. By rigorously evaluating leading LLMs, we demonstrate the impact of various LLM technologies on log analysis performance, focusing on aspects such as self-consistency and few-shot contextual learning. We also discuss findings related to model quantification, Chinese-English question-answering evaluation, and prompt engineering. These findings provide insights into the strengths and weaknesses of LLMs in multilingual environments and the effectiveness of different prompt strategies. Various evaluation methods are employed for different tasks to accurately measure the performance of LLMs in log analysis, ensuring a comprehensive assessment. The insights gained from LogEvals evaluation reveal the strengths and limitations of LLMs in log analysis tasks, providing valuable guidance for researchers and practitioners.

arXiv:2407.00476공식 코드 · Papers with Code

Large Language Models for Power Scheduling: A User-Centric Approach

While traditional optimization and scheduling schemes are designed to meet fixed, predefined system requirements, future systems are moving toward user-driven approaches and personalized services, aiming to achieve high quality-of-experience (QoE) and flexibility. This challenge is particularly pronounced in wireless and digitalized energy networks, where users' requirements have largely not been taken into consideration due to the lack of a common language between users and machines. The emergence of powerful large language models (LLMs) marks a radical departure from traditional system-centric methods into more advanced user-centric approaches by providing a natural communication interface between users and devices. In this paper, for the first time, we introduce a novel architecture for resource scheduling problems by constructing three LLM agents to convert an arbitrary user's voice request (VRQ) into a resource allocation vector. Specifically, we design an LLM intent recognition agent to translate the request into an optimization problem (OP), an LLM OP parameter identification agent, and an LLM OP solving agent. To evaluate system performance, we construct a database of typical VRQs in the context of electric vehicle (EV) charging. As a proof of concept, we primarily use Llama 3 8B. Through testing with different prompt engineering scenarios, the obtained results demonstrate the efficiency of the proposed architecture. The conducted performance analysis allows key insights to be extracted. For instance, having a larger set of candidate OPs to model the real-world problem might degrade the final performance because of a higher recognition/OP classification noise level. All results and codes are open source.

arXiv:2407.01463공식 코드 · Papers with Code

Retrieval-augmented generation in multilingual settings

Retrieval-augmented generation (RAG) has recently emerged as a promising solution for incorporating up-to-date or domain-specific knowledge into large language models (LLMs) and improving LLM factuality, but is predominantly studied in English-only settings. In this work, we consider RAG in the multilingual setting (mRAG), i.e. with user queries and the datastore in 13 languages, and investigate which components and with which adjustments are needed to build a well-performing mRAG pipeline, that can be used as a strong baseline in future works. Our findings highlight that despite the availability of high-quality off-the-shelf multilingual retrievers and generators, task-specific prompt engineering is needed to enable generation in user languages. Moreover, current evaluation metrics need adjustments for multilingual setting, to account for variations in spelling named entities. The main limitations to be addressed in future works include frequent code-switching in non-Latin alphabet languages, occasional fluency errors, wrong reading of the provided documents, or irrelevant retrieval. We release the code for the resulting mRAG baseline pipeline at https://github.com/naver/bergen.

arXiv:2406.19898공식 코드 · Papers with Code

Paraphrase Types Elicit Prompt Engineering Capabilities

Much of the success of modern language models depends on finding a suitable prompt to instruct the model. Until now, it has been largely unknown how variations in the linguistic expression of prompts affect these models. This study systematically and empirically evaluates which linguistic features influence models through paraphrase types, i.e., different linguistic changes at particular positions. We measure behavioral changes for five models across 120 tasks and six families of paraphrases (i.e., morphology, syntax, lexicon, lexico-syntax, discourse, and others). We also control for other prompt engineering factors (e.g., prompt length, lexical diversity, and proximity to training data). Our results show a potential for language models to improve tasks when their prompts are adapted in specific paraphrase types (e.g., 6.7% median gain in Mixtral 8x7B; 5.5% in LLaMA 3 8B). In particular, changes in morphology and lexicon, i.e., the vocabulary used, showed promise in improving prompts. These findings contribute to developing more robust language models capable of handling variability in linguistic expression.

arXiv:2406.19528

Harnessing LLMs for Automated Video Content Analysis: An Exploratory Workflow of Short Videos on Depression

Despite the growing interest in leveraging Large Language Models (LLMs) for content analysis, current studies have primarily focused on text-based content. In the present work, we explored the potential of LLMs in assisting video content analysis by conducting a case study that followed a new workflow of LLM-assisted multimodal content analysis. The workflow encompasses codebook design, prompt engineering, LLM processing, and human evaluation. We strategically crafted annotation prompts to get LLM Annotations in structured form and explanation prompts to generate LLM Explanations for a better understanding of LLM reasoning and transparency. To test LLM's video annotation capabilities, we analyzed 203 keyframes extracted from 25 YouTube short videos about depression. We compared the LLM Annotations with those of two human coders and found that LLM has higher accuracy in object and activity Annotations than emotion and genre Annotations. Moreover, we identified the potential and limitations of LLM's capabilities in annotating videos. Based on the findings, we explore opportunities and challenges for future research and improvements to the workflow. We also discuss ethical concerns surrounding future studies based on LLM-assisted video analysis.

arXiv:2406.19486

LoPT: Low-Rank Prompt Tuning for Parameter Efficient Language Models

In prompt tuning, a prefix or suffix text is added to the prompt, and the embeddings (soft prompts) or token indices (hard prompts) of the prefix/suffix are optimized to gain more control over language models for specific tasks. This approach eliminates the need for hand-crafted prompt engineering or explicit model fine-tuning. Prompt tuning is significantly more parameter-efficient than model fine-tuning, as it involves optimizing partial inputs of language models to produce desired outputs. In this work, we aim to further reduce the amount of trainable parameters required for a language model to perform well on specific tasks. We propose Low-rank Prompt Tuning (LoPT), a low-rank model for prompts that achieves efficient prompt optimization. The proposed method demonstrates similar outcomes to full parameter prompt tuning while reducing the number of trainable parameters by a factor of 5. It also provides promising results compared to the state-of-the-art methods that would require 10 to 20 times more parameters.

arXiv:2406.18627공식 코드 · Papers with Code

AssertionBench: A Benchmark to Evaluate Large-Language Models for Assertion Generation

Assertions have been the de facto collateral for simulation-based and formal verification of hardware designs for over a decade. The quality of hardware verification, \ie, detection and diagnosis of corner-case design bugs, is critically dependent on the quality of the assertions. There has been a considerable amount of research leveraging a blend of data-driven statistical analysis and static analysis to generate high-quality assertions from hardware design source code and design execution trace data. Despite such concerted effort, all prior research struggles to scale to industrial-scale large designs, generates too many low-quality assertions, often fails to capture subtle and non-trivial design functionality, and does not produce any easy-to-comprehend explanations of the generated assertions to understand assertions' suitability to different downstream validation tasks. Recently, with the advent of Large-Language Models (LLMs), there has been a widespread effort to leverage prompt engineering to generate assertions. However, there is little effort to quantitatively establish the effectiveness and suitability of various LLMs for assertion generation. In this paper, we present AssertionBench, a novel benchmark to evaluate LLMs' effectiveness for assertion generation quantitatively. AssertioBench contains 100 curated Verilog hardware designs from OpenCores and formally verified assertions for each design generated from GoldMine and HARM. We use AssertionBench to compare state-of-the-art LLMs to assess their effectiveness in inferring functionally correct assertions for hardware designs. Our experiments demonstrate how LLMs perform relative to each other, the benefits of using more in-context exemplars in generating a higher fraction of functionally correct assertions, and the significant room for improvement for LLM-based assertion generators.

arXiv:2406.18297공식 코드 · Papers with Code

FactFinders at CheckThat! 2024: Refining Check-worthy Statement Detection with LLMs through Data Pruning

The rapid dissemination of information through social media and the Internet has posed a significant challenge for fact-checking, among others in identifying check-worthy claims that fact-checkers should pay attention to, i.e. filtering claims needing fact-checking from a large pool of sentences. This challenge has stressed the need to focus on determining the priority of claims, specifically which claims are worth to be fact-checked. Despite advancements in this area in recent years, the application of large language models (LLMs), such as GPT, has only recently drawn attention in studies. However, many open-source LLMs remain underexplored. Therefore, this study investigates the application of eight prominent open-source LLMs with fine-tuning and prompt engineering to identify check-worthy statements from political transcriptions. Further, we propose a two-step data pruning approach to automatically identify high-quality training data instances for effective learning. The efficiency of our approach is demonstrated through evaluations on the English language dataset as part of the check-worthiness estimation task of CheckThat! 2024. Further, the experiments conducted with data pruning demonstrate that competitive performance can be achieved with only about 44\% of the training data. Our team ranked first in the check-worthiness estimation task in the English language.

arXiv:2406.17888공식 코드 · Papers with Code

CTBench: A Comprehensive Benchmark for Evaluating Language Model Capabilities in Clinical Trial Design

CTBench is introduced as a benchmark to assess language models (LMs) in aiding clinical study design. Given study-specific metadata, CTBench evaluates AI models' ability to determine the baseline features of a clinical trial (CT), which include demographic and relevant features collected at the trial's start from all participants. These baseline features, typically presented in CT publications (often as Table 1), are crucial for characterizing study cohorts and validating results. Baseline features, including confounders and covariates, are also necessary for accurate treatment effect estimation in studies involving observational data. CTBench consists of two datasets: "CT-Repo," containing baseline features from 1,690 clinical trials sourced from clinicaltrials.gov, and "CT-Pub," a subset of 100 trials with more comprehensive baseline features gathered from relevant publications. Two LM-based evaluation methods are developed to compare the actual baseline feature lists against LM-generated responses. "ListMatch-LM" and "ListMatch-BERT" use GPT-4o and BERT scores (at various thresholds), respectively, for evaluation. To establish baseline results, advanced prompt engineering techniques using LLaMa3-70B-Instruct and GPT-4o in zero-shot and three-shot learning settings are applied to generate potential baseline features. The performance of GPT-4o as an evaluator is validated through human-in-the-loop evaluations on the CT-Pub dataset, where clinical experts confirm matches between actual and LM-generated features. The results highlight a promising direction with significant potential for improvement, positioning CTBench as a useful tool for advancing research on AI in CT design and potentially enhancing the efficacy and robustness of CTs.

arXiv:2406.16510

Large Language Models in Student Assessment: Comparing ChatGPT and Human Graders

This study investigates the efficacy of large language models (LLMs) as tools for grading master-level student essays. Utilizing a sample of 60 essays in political science, the study compares the accuracy of grades suggested by the GPT-4 model with those awarded by university teachers. Results indicate that while GPT-4 aligns with human grading standards on mean scores, it exhibits a risk-averse grading pattern and its interrater reliability with human raters is low. Furthermore, modifications in the grading instructions (prompt engineering) do not significantly alter AI performance, suggesting that GPT-4 primarily assesses generic essay characteristics such as language quality rather than adapting to nuanced grading criteria. These findings contribute to the understanding of AI's potential and limitations in higher education, highlighting the need for further development to enhance its adaptability and sensitivity to specific educational assessment requirements.

arXiv:2406.16349

AnnotatedTables: A Large Tabular Dataset with Language Model Annotations

Tabular data is ubiquitous in real-world applications and abundant on the web, yet its annotation has traditionally required human labor, posing a significant scalability bottleneck for tabular machine learning. Our methodology can successfully annotate a large amount of tabular data and can be flexibly steered to generate various types of annotations based on specific research objectives, as we demonstrate with SQL annotation and input-target column annotation as examples. As a result, we release AnnotatedTables, a collection of 32,119 databases with LLM-generated annotations. The dataset includes 405,616 valid SQL programs, making it the largest SQL dataset with associated tabular data that supports query execution. To further demonstrate the value of our methodology and dataset, we perform two follow-up research studies. 1) We investigate whether LLMs can translate SQL programs to Rel programs, a database language previously unknown to LLMs, while obtaining the same execution results. Using our Incremental Prompt Engineering methods based on execution feedback, we show that LLMs can produce adequate translations with few-shot learning. 2) We evaluate the performance of TabPFN, a recent neural tabular classifier trained on Bayesian priors, on 2,720 tables with input-target columns identified and annotated by LLMs. On average, TabPFN performs on par with the baseline AutoML method, though the relative performance can vary significantly from one data table to another, making both models viable for practical applications depending on the situation. Our findings underscore the potential of LLMs in automating the annotation of large volumes of diverse tabular data.

arXiv:2406.16271공식 코드 · Papers with Code

Feature-prompting GBMSeg: One-Shot Reference Guided Training-Free Prompt Engineering for Glomerular Basement Membrane Segmentation

Assessment of the glomerular basement membrane (GBM) in transmission electron microscopy (TEM) is crucial for diagnosing chronic kidney disease (CKD). The lack of domain-independent automatic segmentation tools for the GBM necessitates an AI-based solution to automate the process. In this study, we introduce GBMSeg, a training-free framework designed to automatically segment the GBM in TEM images guided only by a one-shot annotated reference. Specifically, GBMSeg first exploits the robust feature matching capabilities of the pretrained foundation model to generate initial prompt points, then introduces a series of novel automatic prompt engineering techniques across the feature and physical space to optimize the prompt scheme. Finally, GBMSeg employs a class-agnostic foundation segmentation model with the generated prompt scheme to obtain accurate segmentation results. Experimental results on our collected 2538 TEM images confirm that GBMSeg achieves superior segmentation performance with a Dice similarity coefficient (DSC) of 87.27% using only one labeled reference image in a training-free manner, outperforming recently proposed one-shot or few-shot methods. In summary, GBMSeg introduces a distinctive automatic prompt framework that facilitates robust domain-independent segmentation performance without training, particularly advancing the automatic prompting of foundation segmentation models for medical images. Future work involves automating the thickness measurement of segmented GBM and quantifying pathological indicators, holding significant potential for advancing pathology assessments in clinical applications. The source code is available on https://github.com/SnowRain510/GBMSeg

arXiv:2406.15708

Teach Better or Show Smarter? On Instructions and Exemplars in Automatic Prompt Optimization

Large language models have demonstrated remarkable capabilities, but their performance is heavily reliant on effective prompt engineering. Automatic prompt optimization (APO) methods are designed to automate this and can be broadly categorized into those targeting instructions (instruction optimization, IO) vs. those targeting exemplars (exemplar optimization, EO). Despite their shared objective, these have evolved rather independently, with IO receiving more research attention recently. This paper seeks to bridge this gap by comprehensively comparing the performance of representative IO and EO techniques both isolation and combination on a diverse set of challenging tasks. Our findings reveal that intelligently reusing model-generated input-output pairs obtained from evaluating prompts on the validation set as exemplars, consistently improves performance on top of IO methods but is currently under-investigated. We also find that despite the recent focus on IO, how we select exemplars can outweigh how we optimize instructions, with EO strategies as simple as random search outperforming state-of-the-art IO methods with seed instructions without any optimization. Moreover, we observe a synergy between EO and IO, with optimal combinations surpassing the individual contributions. We conclude that studying exemplar optimization both as a standalone method and its optimal combination with instruction optimization remain a crucial aspect of APO and deserve greater consideration in future research, even in the era of highly capable instruction-following models.

arXiv:2406.14596

VLM Agents Generate Their Own Memories: Distilling Experience into Embodied Programs of Thought

Large-scale LLMs and VLMs excel at few-shot learning but require high-quality examples. We introduce In-Context Abstraction Learning (ICAL), which iteratively refines suboptimal trajectories into high-quality data with optimized actions and detailed reasoning. Given an inefficient demonstration, a VLM corrects actions and annotates causal relationships, object states, subgoals, and task-relevant visuals, forming "programs of thought." With human feedback, these programs are improved as the agent executes them in a similar environment. The resulting examples, used as prompt context or fine-tuning data, significantly boost decision-making while reducing human feedback needs. ICAL surpasses state-of-the-art in TEACh (dialogue-based instruction following), VisualWebArena (multimodal web agents), and Ego4D (egocentric video action anticipation). In TEACh, combining fine-tuning and retrieval on ICAL examples outperforms raw human demonstrations and expert examples, achieving a 17.5% increase in goal-condition success. In VisualWebArena, retrieval-augmented GPT-4V with ICAL improves task success rate 1.6x over GPT-4V, while fine-tuning Qwen2-VL achieves a 2.8x improvement. In Ego4D, ICAL outperforms few-shot GPT-4V and remains competitive with supervised models. Overall, ICAL scales 2x better than raw human demonstrations and reduces manual prompt engineering.

arXiv:2406.10248공식 코드 · Papers with Code

On the Worst Prompt Performance of Large Language Models

The performance of large language models (LLMs) is acutely sensitive to the phrasing of prompts, which raises significant concerns about their reliability in real-world scenarios. Existing studies often divide prompts into task-level instructions and case-level inputs and primarily focus on evaluating and improving robustness against variations in tasks-level instructions. However, this setup fails to fully address the diversity of real-world user queries and assumes the existence of task-specific datasets. To address these limitations, we introduce RobustAlpacaEval, a new benchmark that consists of semantically equivalent case-level queries and emphasizes the importance of using the worst prompt performance to gauge the lower bound of model performance. Extensive experiments on RobustAlpacaEval with ChatGPT and six open-source LLMs from the Llama, Mistral, and Gemma families uncover substantial variability in model performance; for instance, a difference of 45.48% between the worst and best performance for the Llama-2-70B-chat model, with its worst performance dipping as low as 9.38%. We further illustrate the difficulty in identifying the worst prompt from both model-agnostic and model-dependent perspectives, emphasizing the absence of a shortcut to characterize the worst prompt. We also attempt to enhance the worst prompt performance using existing prompt engineering and prompt consistency methods, but find that their impact is limited. These findings underscore the need to create more resilient LLMs that can maintain high performance across diverse prompts. Data and code are available at https://github.com/cbwbuaa/On-the-Worst-Prompt- Performance-of-LLMs.

arXiv:2406.15259공식 코드 · Papers with Code

V-RECS, a Low-Cost LLM4VIS Recommender with Explanations, Captioning and Suggestions

NL2VIS (natural language to visualization) is a promising and recent research area that involves interpreting natural language queries and translating them into visualizations that accurately represent the underlying data. As we navigate the era of big data, NL2VIS holds considerable application potential since it greatly facilitates data exploration by non-expert users. Following the increasingly widespread usage of generative AI in NL2VIS applications, in this paper we present V-RECS, the first LLM-based Visual Recommender augmented with explanations(E), captioning(C), and suggestions(S) for further data exploration. V-RECS' visualization narratives facilitate both response verification and data exploration by non-expert users. Furthermore, our proposed solution mitigates computational, controllability, and cost issues associated with using powerful LLMs by leveraging a methodology to effectively fine-tune small models. To generate insightful visualization narratives, we use Chain-of-Thoughts (CoT), a prompt engineering technique to help LLM identify and generate the logical steps to produce a correct answer. Since CoT is reported to perform poorly with small LLMs, we adopted a strategy in which a large LLM (GPT-4), acting as a Teacher, generates CoT-based instructions to fine-tune a small model, Llama-2-7B, which plays the role of a Student. Extensive experiments-based on a framework for the quantitative evaluation of AI-based visualizations and on manual assessment by a group of participants-show that V-RECS achieves performance scores comparable to GPT-4, at a much lower cost. The efficacy of the V-RECS teacher-student paradigm is also demonstrated by the fact that the un-tuned Llama fails to perform the task in the vast majority of test cases. We release V-RECS for the visualization community to assist visualization designers throughout the entire visualization generation process.

arXiv:2406.13106

Accelerating Complex Disease Treatment through Network Medicine and GenAI: A Case Study on Drug Repurposing for Breast Cancer

The objective of this research is to introduce a network specialized in predicting drugs that can be repurposed by investigating real-world evidence sources, such as clinical trials and biomedical literature. Specifically, it aims to generate drug combination therapies for complex diseases (e.g., cancer, Alzheimer's). We present a multilayered network medicine approach, empowered by a highly configured ChatGPT prompt engineering system, which is constructed on the fly to extract drug mentions in clinical trials. Additionally, we introduce a novel algorithm that connects real-world evidence with disease-specific signaling pathways (e.g., KEGG database). This sheds light on the repurposability of drugs if they are found to bind with one or more protein constituents of a signaling pathway. To demonstrate, we instantiated the framework for breast cancer and found that, out of 46 breast cancer signaling pathways, the framework identified 38 pathways that were covered by at least two drugs. This evidence signals the potential for combining those drugs. Specifically, the most covered signaling pathway, ID hsa:2064, was covered by 108 drugs, some of which can be combined. Conversely, the signaling pathway ID hsa:1499 was covered by only two drugs, indicating a significant gap for further research. Our network medicine framework, empowered by GenAI, shows promise in identifying drug combinations with a high degree of specificity, knowing the exact signaling pathways and proteins that serve as targets. It is noteworthy that ChatGPT successfully accelerated the process of identifying drug mentions in clinical trials, though further investigations are required to determine the relationships among the drug mentions.