Breast cancer stands as a prevalent cause of fatality among females on a global scale, with prompt detection playing a pivotal role in diminishing mortality rates. The utilization of ultrasound scans in the BUSI dataset for medical imagery pertaining to breast cancer has exhibited commendable segmentation outcomes through the application of UNet and UNet++ networks. Nevertheless, a notable drawback of these models resides in their inattention towards the temporal aspects embedded within the images. This research endeavors to enrich the UNet++ architecture by integrating LSTM layers and self-attention mechanisms to exploit temporal characteristics for segmentation purposes. Furthermore, the incorporation of a Multiscale Feature Extraction Module aims to grasp varied scale features within the UNet++. Through the amalgamation of our proposed methodology with data augmentation on the BUSI with GT dataset, an accuracy rate of 98.88%, specificity of 99.53%, precision of 95.34%, sensitivity of 91.20%, F1-score of 93.74, and Dice coefficient of 92.74% are achieved. These findings demonstrate competitiveness with cutting-edge techniques outlined in existing literature.
Uncertainty quantification (UQ) is essential for assessing the reliability of Earth observation (EO) products. However, the extensive use of machine learning models in EO introduces an additional layer of complexity, as those models themselves are inherently uncertain. While various UQ methods do exist for machine learning models, their performance on EO datasets remains largely unevaluated. A key challenge in the community is the absence of the ground truth for uncertainty, i.e. how certain the uncertainty estimates are, apart from the labels for the image/signal. This article fills this gap by introducing three benchmark datasets specifically designed for UQ in EO machine learning models. These datasets address three common problem types in EO: regression, image segmentation, and scene classification. They enable a transparent comparison of different UQ methods for EO machine learning models. We describe the creation and characteristics of each dataset, including data sources, preprocessing steps, and label generation, with a particular focus on calculating the reference uncertainty. We also showcase baseline performance of several machine learning models on each dataset, highlighting the utility of these benchmarks for model development and comparison. Overall, this article offers a valuable resource for researchers and practitioners working in artificial intelligence for EO, promoting a more accurate and reliable quality measure of the outputs of machine learning models. The dataset and code are accessible via https://gitlab.lrz.de/ai4eo/WG_Uncertainty.
In recent years, advanced U-like networks have demonstrated remarkable performance in medical image segmentation tasks. However, their drawbacks, including excessive parameters, high computational complexity, and slow inference speed, pose challenges for practical implementation in scenarios with limited computational resources. Existing lightweight U-like networks have alleviated some of these problems, but they often have pre-designed structures and consist of inseparable modules, limiting their application scenarios. In this paper, we propose three plug-and-play decoders by employing different discretization methods of the neural memory Ordinary Differential Equations (nmODEs). These decoders integrate features at various levels of abstraction by processing information from skip connections and performing numerical operations on upward path. Through experiments on the PH2, ISIC2017, and ISIC2018 datasets, we embed these decoders into different U-like networks, demonstrating their effectiveness in significantly reducing the number of parameters and FLOPs while maintaining performance. In summary, the proposed discretized nmODEs decoders are capable of reducing the number of parameters by about 20% ~ 50% and FLOPs by up to 74%, while possessing the potential to adapt to all U-like networks. Our code is available at https://github.com/nayutayuki/Lightweight-nmODE-Decoders-For-U-like-networks.
Crack detection is a critical task in structural health monitoring, aimed at assessing the structural integrity of bridges, buildings, and roads to prevent potential failures. Vision-based crack detection has become the mainstream approach due to its ease of implementation and effectiveness. Fusing infrared (IR) channels with red, green and blue (RGB) channels can enhance feature representation and thus improve crack detection. However, IR and RGB channels often differ in resolution. To align them, higher-resolution RGB images typically need to be downsampled to match the IR image resolution, which leads to the loss of fine details. Moreover, crack detection performance is restricted by the limited receptive fields and high computational complexity of traditional image segmentation networks. Inspired by the recently proposed Mamba neural architecture, this study introduces a two-stage paradigm called MSCrackMamba, which leverages Vision Mamba along with a super-resolution network to address these challenges. Specifically, to align IR and RGB channels, we first apply super-resolution to IR channels to match the resolution of RGB channels for data fusion. Vision Mamba is then adopted as the backbone network, while UperNet is employed as the decoder for crack detection. Our approach is validated on the large-scale Crack Detection dataset Crack900, demonstrating an improvement of 3.55% in mIoU compared to the best-performing baseline methods.
In generative models, two paradigms have gained attraction in various applications: next-set prediction-based Masked Generative Models and next-noise prediction-based Non-Autoregressive Models, e.g., Diffusion Models. In this work, we propose using discrete-state models to connect them and explore their scalability in the vision domain. First, we conduct a step-by-step analysis in a unified design space across two types of models including timestep-independence, noise schedule, temperature, guidance strength, etc in a scalable manner. Second, we re-cast typical discriminative tasks, e.g., image segmentation, as an unmasking process from [MASK] tokens on a discrete-state model. This enables us to perform various sampling processes, including flexible conditional sampling by only training once to model the joint distribution. All aforementioned explorations lead to our framework named Discrete Interpolants, which enables us to achieve state-of-the-art or competitive performance compared to previous discrete-state based methods in various benchmarks, like ImageNet256, MS COCO, and video dataset FaceForensics. In summary, by leveraging [MASK] in discrete-state models, we can bridge Masked Generative and Non-autoregressive Diffusion models, as well as generative and discriminative tasks.
We propose an unsupervised image segmentation method using features from pre-trained text-to-image diffusion models. Inspired by classic spectral clustering approaches, we construct adjacency matrices from self-attention layers between image patches and recursively partition using Normalised Cuts. A key insight is that self-attention probability distributions, which capture semantic relations between patches, can be interpreted as a transition matrix for random walks across the image. We leverage this by first using Random Walk Normalized Cuts directly on these self-attention activations to partition the image, minimizing transition probabilities between clusters while maximizing coherence within clusters. Applied recursively, this yields a hierarchical segmentation that reflects the rich semantics in the pre-trained attention layers, without any additional training. Next, we explore other ways to build the NCuts adjacency matrix from features, and how we can use the random walk interpretation of self-attention to capture long-range relationships. Finally, we propose an approach to automatically determine the NCut cost criterion, avoiding the need to tune this manually. We quantitatively analyse the effect incorporating different features, a constant versus dynamic NCut threshold, and incorporating multi-node paths when constructing the NCuts adjacency matrix. We show that our approach surpasses all existing methods for zero-shot unsupervised segmentation, achieving state-of-the-art results on COCO-Stuff-27 and Cityscapes.
Object permanence in humans is a fundamental cue that helps in understanding persistence of objects, even when they are fully occluded in the scene. Present day methods in object segmentation do not account for this amodal nature of the world, and only work for segmentation of visible or modal objects. Few amodal methods exist; single-image segmentation methods cannot handle high-levels of occlusions which are better inferred using temporal information, and multi-frame methods have focused solely on segmenting rigid objects. To this end, we propose to tackle video amodal segmentation by formulating it as a conditional generation task, capitalizing on the foundational knowledge in video generative models. Our method is simple; we repurpose these models to condition on a sequence of modal mask frames of an object along with contextual pseudo-depth maps, to learn which object boundary may be occluded and therefore, extended to hallucinate the complete extent of an object. This is followed by a content completion stage which is able to inpaint the occluded regions of an object. We benchmark our approach alongside a wide array of state-of-the-art methods on four datasets and show a dramatic improvement of upto 13% for amodal segmentation in an object's occluded region.
Recent open-vocabulary segmentation methods adopt mask generators to predict segmentation masks and leverage pre-trained vision-language models, e.g., CLIP, to classify these masks via mask pooling. Although these approaches show promising results, it is counterintuitive that accurate masks often fail to yield accurate classification results through pooling CLIP image embeddings within the mask regions. In this paper, we reveal the performance limitations of mask pooling and introduce Mask-Adapter, a simple yet effective method to address these challenges in open-vocabulary segmentation. Compared to directly using proposal masks, our proposed Mask-Adapter extracts semantic activation maps from proposal masks, providing richer contextual information and ensuring alignment between masks and CLIP. Additionally, we propose a mask consistency loss that encourages proposal masks with similar IoUs to obtain similar CLIP embeddings to enhance models' robustness to varying predicted masks. Mask-Adapter integrates seamlessly into open-vocabulary segmentation methods based on mask pooling in a plug-and-play manner, delivering more accurate classification results. Extensive experiments across several zero-shot benchmarks demonstrate significant performance gains for the proposed Mask-Adapter on several well-established methods. Notably, Mask-Adapter also extends effectively to SAM and achieves impressive results on several open-vocabulary segmentation datasets. Code and models are available at \url{https://github.com/hustvl/MaskAdapter}.
Medical image segmentation has recently demonstrated impressive progress with deep neural networks, yet the heterogeneous modalities and scarcity of mask annotations limit the development of segmentation models on unannotated modalities. This paper investigates a new paradigm for leveraging generative models in medical applications: controllably synthesizing data for unannotated modalities, without requiring registered data pairs. Specifically, we make the following contributions in this paper: (i) we collect and curate a large-scale radiology image-text dataset, MedGen-1M, comprising modality labels, attributes, region, and organ information, along with a subset of organ mask annotations, to support research in controllable medical image generation; (ii) we propose a diffusion-based data engine, termed MRGen, which enables generation conditioned on text prompts and masks, synthesizing MR images for diverse modalities lacking mask annotations, to train segmentation models on unannotated modalities; (iii) we conduct extensive experiments across various modalities, illustrating that our data engine can effectively synthesize training samples and extend MRI segmentation towards unannotated modalities.
Image segmentation foundation models (SFMs) like Segment Anything Model (SAM) have achieved impressive zero-shot and interactive segmentation across diverse domains. However, they struggle to segment objects with certain structures, particularly those with dense, tree-like morphology and low textural contrast from their surroundings. These failure modes are crucial for understanding the limitations of SFMs in real-world applications. To systematically study this issue, we introduce interpretable metrics quantifying object tree-likeness and textural separability. On carefully controlled synthetic experiments and real-world datasets, we show that SFM performance (e.g., SAM, SAM 2, HQ-SAM) noticeably correlates with these factors. We link these failures to "textural confusion", where models misinterpret local structure as global texture, causing over-segmentation or difficulty distinguishing objects from similar backgrounds. Notably, targeted fine-tuning fails to resolve this issue, indicating a fundamental limitation. Our study provides the first quantitative framework for modeling the behavior of SFMs on challenging structures, offering interpretable insights into their segmentation capabilities.
Advanced Driver Assistance Systems (ADAS) are designed with the main purpose of increasing the safety and comfort of vehicle occupants. Most of current computer vision-based ADAS perform detection and tracking tasks quite successfully under regular conditions, but are not completely reliable, particularly under adverse weather and changing lighting conditions, neither in complex situations with many overlapping objects. In this work we explore the use of hyperspectral imaging (HSI) in ADAS on the assumption that the distinct near infrared (NIR) spectral reflectances of different materials can help to better separate the objects in a driving scene. In particular, this paper describes some experimental results of the application of fully convolutional networks (FCN) to the image segmentation of HSI for ADAS applications. More specifically, our aim is to investigate to what extent the spatial features codified by convolutional filters can be helpful to improve the performance of HSI segmentation systems. With that aim, we use the HSI-Drive v1.1 dataset, which provides a set of labelled images recorded in real driving conditions with a small-size snapshot NIR-HSI camera. Finally, we analyze the implementability of such a HSI segmentation system by prototyping the developed FCN model together with the necessary hyperspectral cube preprocessing stage and characterizing its performance on an MPSoC.
Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes. Traditional domain generalization methods typically require inclusion of parts of the test domain within the training set, which is not always feasible in clinical settings with limited diverse data. Additionally, although diffusion models have demonstrated strong capabilities in image generation and style transfer, they often fail to preserve the critical structural information necessary for precise medical analysis. To address these issues, we propose a novel medical image segmentation method that combines diffusion models and Structure-Preserving Network for structure-aware one-shot image stylization. Our approach effectively mitigates domain shifts by transforming images from various sources into a consistent style while maintaining the location, size, and shape of lesions. This ensures robust and accurate segmentation even when the target domain is absent from the training data. Experimental evaluations on colonoscopy polyp segmentation and skin lesion segmentation datasets show that our method enhances the robustness and accuracy of segmentation models, achieving superior performance metrics compared to baseline models without style transfer. This structure-aware stylization framework offers a practical solution for improving medical image segmentation across diverse domains, facilitating more reliable clinical diagnoses.
We propose a novel two-stage semi-supervised learning approach for training downsampling-upsampling semantic segmentation architectures. The first stage does not use backpropagation. Rather, it exploits the bio-inspired Hebbian principle "fire together, wire together" as a local learning rule for updating the weights of both convolutional and transpose-convolutional layers, allowing unsupervised discovery of data features. In the second stage, the model is fine-tuned with standard backpropagation on a small subset of labeled data. We evaluate our methodology through experiments conducted on several widely used biomedical datasets, deeming that this domain is paramount in computer vision and is notably impacted by data scarcity. Results show that our proposed method outperforms SOTA approaches across different levels of label availability. Furthermore, we show that using our unsupervised stage to initialize the SOTA approaches leads to performance improvements. The code to replicate our experiments can be found at: https://github.com/ciampluca/hebbian-medical-image-segmentation
Exemplar-based semantic image synthesis aims to generate images aligned with given semantic content while preserving the appearance of an exemplar image. Conventional structure-guidance models, such as ControlNet, are limited in that they cannot directly utilize exemplar images as input, relying instead solely on text prompts to control appearance. Recent tuning-free approaches address this limitation by transferring local appearance from the exemplar image to the synthesized image through implicit cross-image matching in the augmented self-attention mechanism of pre-trained diffusion models. However, these methods face challenges when applied to content-rich scenes with significant geometric deformations, such as driving scenes. In this paper, we propose the Appearance Matching Adapter (AM-Adapter), a learnable framework that enhances cross-image matching within augmented self-attention by incorporating semantic information from segmentation maps. To effectively disentangle generation and matching processes, we adopt a stage-wise training approach. Initially, we train the structure-guidance and generation networks, followed by training the AM-Adapter while keeping the other networks frozen. During inference, we introduce an automated exemplar retrieval method to efficiently select exemplar image-segmentation pairs. Despite utilizing a limited number of learnable parameters, our method achieves state-of-the-art performance, excelling in both semantic alignment preservation and local appearance fidelity. Extensive ablation studies further validate our design choices. Code and pre-trained weights will be publicly available.: https://cvlab-kaist.github.io/AM-Adapter/
Few-shot Semantic Segmentation(FSS)aim to adapt a pre-trained model to new classes with as few as a single labeled training sample per class. The existing prototypical work used in natural image scenarios biasedly focus on capturing foreground's discrimination while employing a simplistic representation for background, grounded on the inherent observation separation between foreground and background. However, this paradigm is not applicable to medical images where the foreground and background share numerous visual features, necessitating a more detailed description for background. In this paper, we present a new pluggable Background-fused prototype(Bro)approach for FSS in medical images. Instead of finding a commonality of background subjects in support image, Bro incorporates this background with two pivot designs. Specifically, Feature Similarity Calibration(FeaC)initially reduces noise in the support image by employing feature cross-attention with the query image. Subsequently, Hierarchical Channel Adversarial Attention(HiCA)merges the background into comprehensive prototypes. We achieve this by a channel groups-based attention mechanism, where an adversarial Mean-Offset structure encourages a coarse-to-fine fusion. Extensive experiments show that previous state-of-the-art methods, when paired with Bro, experience significant performance improvements. This demonstrates a more integrated way to represent backgrounds specifically for medical image.
The remarkable success of deep learning methods in solving computer vision problems, such as image classification, object detection, scene understanding, image segmentation, etc., has paved the way for their application in biomedical imaging. One such application is in the field of CT image denoising, whereby deep learning methods are proposed to recover denoised images from noisy images acquired at low radiation. Outputs derived from applying deep learning denoising algorithms may appear clean and visually pleasing; however, the underlying diagnostic image quality may not be on par with their normal-dose CT counterparts. In this work, we assessed the image quality of deep learning denoising algorithms by making use of visual perception- and data fidelity-based task-agnostic metrics (like the PSNR and the SSIM) - commonly used in the computer vision - and a task-based detectability assessment (the LCD) - extensively used in the CT imaging. When compared against normal-dose CT images, the deep learning denoisers outperformed low-dose CT based on metrics like the PSNR (by 2.4 to 3.8 dB) and SSIM (by 0.05 to 0.11). However, based on the LCD performance, the detectability using quarter-dose denoised outputs was inferior to that obtained using normal-dose CT scans.
Segmenting internal structure from echocardiography is essential for the diagnosis and treatment of various heart diseases. Semi-supervised learning shows its ability in alleviating annotations scarcity. While existing semi-supervised methods have been successful in image segmentation across various medical imaging modalities, few have attempted to design methods specifically addressing the challenges posed by the poor contrast, blurred edge details and noise of echocardiography. These characteristics pose challenges to the generation of high-quality pseudo-labels in semi-supervised segmentation based on Mean Teacher. Inspired by human reflection on erroneous practices, we devise an error reflection strategy for echocardiography semi-supervised segmentation architecture. The process triggers the model to reflect on inaccuracies in unlabeled image segmentation, thereby enhancing the robustness of pseudo-label generation. Specifically, the strategy is divided into two steps. The first step is called reconstruction reflection. The network is tasked with reconstructing authentic proxy images from the semantic masks of unlabeled images and their auxiliary sketches, while maximizing the structural similarity between the original inputs and the proxies. The second step is called guidance correction. Reconstruction error maps decouple unreliable segmentation regions. Then, reliable data that are more likely to occur near high-density areas are leveraged to guide the optimization of unreliable data potentially located around decision boundaries. Additionally, we introduce an effective data augmentation strategy, termed as multi-scale mixing up strategy, to minimize the empirical distribution gap between labeled and unlabeled images and perceive diverse scales of cardiac anatomical structures. Extensive experiments demonstrate the competitiveness of the proposed method.
Despite significant advances in vision-language understanding, implementing image segmentation within multimodal architectures remains a fundamental challenge in modern artificial intelligence systems. Existing vision-language models, which primarily rely on backbone architectures or CLIP-based embedding learning, demonstrate inherent limitations in fine-grained spatial localization and operational capabilities. This paper introduces SJTU: Spatial Judgments in Multimodal Models - Towards Unified Segmentation through Coordinate Detection, a framework that leverages spatial coordinate understanding to bridge vision-language interaction and precise segmentation, enabling accurate target identification through natural language instructions. The framework presents an approach for integrating segmentation techniques with vision-language models through spatial inference in multimodal space. By utilizing normalized coordinate detection for bounding boxes and transforming them into actionable segmentation outputs, we establish a connection between spatial and language representations in multimodal architectures. Experimental results demonstrate superior performance across benchmark datasets, achieving IoU scores of 0.5958 on COCO 2017 and 0.6758 on Pascal VOC. Testing on a single NVIDIA RTX 3090 GPU with 512x512 resolution images yields an average inference time of 7 seconds per image, demonstrating the framework's effectiveness in both accuracy and practical deployability. The project code is available at https://github.com/jw-chae/SJTU
Deep supervised learning has achieved remarkable success across a wide range of tasks, yet it remains susceptible to overfitting when confronted with noisy labels. To address this issue, noise-robust loss functions offer an effective solution for enhancing learning in the presence of label noise. In this work, we systematically investigate the limitation of the recently proposed Active Passive Loss (APL), which employs Mean Absolute Error (MAE) as its passive loss function. Despite the robustness brought by MAE, one of its key drawbacks is that it pays equal attention to clean and noisy samples; this feature slows down convergence and potentially makes training difficult, particularly in large-scale datasets. To overcome these challenges, we introduce a novel loss function class, termed Normalized Negative Loss Functions (NNLFs), which serve as passive loss functions within the APL framework. NNLFs effectively address the limitations of MAE by concentrating more on memorized clean samples. By replacing MAE in APL with our proposed NNLFs, we enhance APL and present a new framework called Active Negative Loss (ANL). Moreover, in non-symmetric noise scenarios, we propose an entropy-based regularization technique to mitigate the vulnerability to the label imbalance. Extensive experiments demonstrate that the new loss functions adopted by our ANL framework can achieve better or comparable performance to state-of-the-art methods across various label noise types and in image segmentation tasks. The source code is available at: https://github.com/Virusdoll/Active-Negative-Loss.
The segmentation of endoscopic images plays a vital role in computer-aided diagnosis and treatment. The advancements in deep learning have led to the employment of numerous models for endoscopic tumor segmentation, achieving promising segmentation performance. Despite recent advancements, precise segmentation remains challenging due to limited annotations and the issue of low contrast. To address these issues, we propose a novel semi-supervised segmentation framework termed LoCo via low-contrast-enhanced contrastive learning (LCC). This innovative approach effectively harnesses the vast amounts of unlabeled data available for endoscopic image segmentation, improving both accuracy and robustness in the segmentation process. Specifically, LCC incorporates two advanced strategies to enhance the distinctiveness of low-contrast pixels: inter-class contrast enhancement (ICE) and boundary contrast enhancement (BCE), enabling models to segment low-contrast pixels among malignant tumors, benign tumors, and normal tissues. Additionally, a confidence-based dynamic filter (CDF) is designed for pseudo-label selection, enhancing the utilization of generated pseudo-labels for unlabeled data with a specific focus on minority classes. Extensive experiments conducted on two public datasets, as well as a large proprietary dataset collected over three years, demonstrate that LoCo achieves state-of-the-art results, significantly outperforming previous methods. The source code of LoCo is available at the URL of \href{https://github.com/AnoK3111/LoCo}{https://github.com/AnoK3111/LoCo}.