The application of methods based on Neural Radiance Fields (NeRF) and 3D Gaussian Splatting (3D GS) have steadily gained popularity in the field of 3D object segmentation in static scenes. These approaches demonstrate efficacy in a range of 3D scene understanding and editing tasks. Nevertheless, the 4D object segmentation of dynamic scenes remains an underexplored field due to the absence of a sufficiently extensive and accurately labelled multi-view video dataset. In this paper, we present MUVOD, a new multi-view video dataset for training and evaluating object segmentation in reconstructed real-world scenarios. The 17 selected scenes, describing various indoor or outdoor activities, are collected from different sources of datasets originating from various types of camera rigs. Each scene contains a minimum of 9 views and a maximum of 46 views. We provide 7830 RGB images (30 frames per video) with their corresponding segmentation mask in 4D motion, meaning that any object of interest in the scene could be tracked across temporal frames of a given view or across different views belonging to the same camera rig. This dataset, which contains 459 instances of 73 categories, is intended as a basic benchmark for the evaluation of multi-view video segmentation methods. We also present an evaluation metric and a baseline segmentation approach to encourage and evaluate progress in this evolving field. Additionally, we propose a new benchmark for 3D object segmentation task with a subset of annotated multi-view images selected from our MUVOD dataset. This subset contains 50 objects of different conditions in different scenarios, providing a more comprehensive analysis of state-of-the-art 3D object segmentation methods. Our proposed MUVOD dataset is available at https://volumetric-repository.labs.b-com.com/#/muvod.
Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel Human-AI collaborative framework for medical image segmentation that substantially reduces the annotation burden by eliminating the need for explicit manual pixel-level labeling. The core innovation lies in a preference learning paradigm, where human experts provide minimal, intuitive feedback -- simply indicating whether an AI-generated segmentation is better or worse than a previous version. The framework comprises four key components: (1) an adaptable foundation model (FM) for feature extraction, (2) label propagation based on feature similarity, (3) a clicking agent that learns from human better-or-worse feedback to decide where to click and with which label, and (4) a multi-round segmentation learning procedure that trains a state-of-the-art segmentation network using pseudo-labels generated by the clicking agent and FM-based label propagation. Experiments on three public datasets demonstrate that the proposed approach achieves competitive segmentation performance using only binary preference feedback, without requiring experts to directly manually annotate the images.
Pediatric medical imaging presents unique challenges due to significant anatomical and developmental differences compared to adults. Direct application of segmentation models trained on adult data often yields suboptimal performance, particularly for small or rapidly evolving structures. To address these challenges, several strategies leveraging the nnU-Net framework have been proposed, differing along four key axes: (i) the fingerprint dataset (adult, pediatric, or a combination thereof) from which the Training Plan -including the network architecture-is derived; (ii) the Learning Set (adult, pediatric, or mixed), (iii) Data Augmentation parameters, and (iv) the Transfer learning method (finetuning versus continual learning). In this work, we introduce PSAT (Pediatric Segmentation Approaches via Adult Augmentations and Transfer learning), a systematic study that investigates the impact of these axes on segmentation performance. We benchmark the derived strategies on two pediatric CT datasets and compare them with state-of-theart methods, including a commercial radiotherapy solution. PSAT highlights key pitfalls and provides actionable insights for improving pediatric segmentation. Our experiments reveal that a training plan based on an adult fingerprint dataset is misaligned with pediatric anatomy-resulting in significant performance degradation, especially when segmenting fine structures-and that continual learning strategies mitigate institutional shifts, thus enhancing generalization across diverse pediatric datasets. The code is available at https://github.com/ICANS-Strasbourg/PSAT.
The annotation bottleneck in semantic segmentation has driven significant interest in few-shot segmentation, which aims to develop segmentation models capable of generalizing rapidly to novel classes using minimal exemplars. Conventional training paradigms typically generate query prior maps by extracting masked-area features from support images, followed by making predictions guided by these prior maps. However, current approaches remain constrained by two critical limitations stemming from inter- and intra-image discrepancies, both of which significantly degrade segmentation performance: 1) The semantic gap between support and query images results in mismatched features and inaccurate prior maps; 2) Visually similar yet semantically distinct regions within support or query images lead to false negative or false positive predictions. We propose a novel FSS method called \textbf{I$^2$R}: 1) Using category-specific high level representations which aggregate global semantic cues from support and query images, enabling more precise inter-image region localization and address the first limitation. 2) Directional masking strategy that suppresses inconsistent support-query pixel pairs, which exhibit high feature similarity but conflicting mask, to mitigate the second issue. Experiments demonstrate that our method outperforms state-of-the-art approaches, achieving improvements of 1.9\% and 2.1\% in mIoU under the 1-shot setting on PASCAL-5$^i$ and COCO-20$^i$ benchmarks, respectively.
Image segmentation plays a vital role in the medical field by isolating organs or regions of interest from surrounding areas. Traditionally, segmentation models are trained on a specific organ or a disease, limiting their ability to handle other organs and diseases. At present, few advanced models can perform multi-organ or multi-disease segmentation, offering greater flexibility. Also, recently, prompt-based image segmentation has gained attention as a more flexible approach. It allows models to segment areas based on user-provided prompts. Despite these advances, there has been no dedicated work on prompt-based interactive multi-organ and multi-disease segmentation, especially for Chest X-rays. This work presents two main contributions: first, generating doodle prompts by medical experts of a collection of datasets from multiple sources with 23 classes, including 6 organs and 17 diseases, specifically designed for prompt-based Chest X-ray segmentation. Second, we introduce Prompt2SegCXR, a lightweight model for accurately segmenting multiple organs and diseases from Chest X-rays. The model incorporates multi-stage feature fusion, enabling it to combine features from various network layers for better spatial and semantic understanding, enhancing segmentation accuracy. Compared to existing pre-trained models for prompt-based image segmentation, our model scores well, providing a reliable solution for segmenting Chest X-rays based on user prompts.
Interactive segmentation (IS) allows users to iteratively refine object boundaries with minimal cues, such as positive and negative clicks. While the Segment Anything Model (SAM) has garnered attention in the IS community for its promptable segmentation capabilities, it often struggles in specialized domains or when handling complex scenarios (e.g., camouflaged or multi-part objects). To overcome these challenges, we propose DC-TTA, a novel test-time adaptation (TTA) framework that adapts SAM on a per-sample basis by leveraging user interactions as supervision. Instead of forcing a single model to incorporate all user clicks at once, DC-TTA partitions the clicks into more coherent subsets, each processed independently via TTA with a separated model. This Divide-and-Conquer strategy reduces conflicts among diverse cues and enables more localized updates. Finally, we merge the adapted models to form a unified predictor that integrates the specialized knowledge from each subset. Experimental results across various benchmarks demonstrate that DC-TTA significantly outperforms SAM's zero-shot results and conventional TTA methods, effectively handling complex tasks such as camouflaged object segmentation with fewer interactions and improved accuracy.
Reliable semantic segmentation of open environments is essential for intelligent systems, yet significant problems remain: 1) Existing RGB-T semantic segmentation models mainly rely on low-level visual features and lack high-level textual information, which struggle with accurate segmentation when categories share similar visual characteristics. 2) While SAM excels in instance-level segmentation, integrating it with thermal images and text is hindered by modality heterogeneity and computational inefficiency. To address these, we propose TASeg, a text-aware RGB-T segmentation framework by using Low-Rank Adaptation (LoRA) fine-tuning technology to adapt vision foundation models. Specifically, we propose a Dynamic Feature Fusion Module (DFFM) in the image encoder, which effectively merges features from multiple visual modalities while freezing SAM's original transformer blocks. Additionally, we incorporate CLIP-generated text embeddings in the mask decoder to enable semantic alignment, which further rectifies the classification error and improves the semantic understanding accuracy. Experimental results across diverse datasets demonstrate that our method achieves superior performance in challenging scenarios with fewer trainable parameters.
The recent advancements in large foundation models have driven the success of open-set image segmentation, a task focused on segmenting objects beyond predefined categories. Among various prompt types (such as points, boxes, texts, and visual references), visual reference segmentation stands out for its unique flexibility and strong zero-shot capabilities. Recently, several SAM-based methods have made notable progress in this task by automatically generating prompts to guide SAM. However, these methods often generate prompts at object boundaries due to suboptimal prompt encoder, which results in instability and reduced robustness. In this work, we introduce ProSAM, a simple but effective method to address the stability challenges we identified in existing SAM-based visual reference segmentation approaches. By learning a variational prompt encoder to predict multivariate prompt distributions, ProSAM avoids generating prompts that lie in unstable regions, overcoming the instability caused by less robust prompts. Our approach consistently surpasses state-of-the-art methods on the Pascal-5$^i$ and COCO-20$^i$ datasets, providing a more robust solution for visual reference segmentation.
Referring Remote Sensing Image Segmentation provides a flexible and fine-grained framework for remote sensing scene analysis via vision-language collaborative interpretation. Current approaches predominantly utilize a three-stage pipeline encompassing dual-modal encoding, cross-modal interaction, and pixel decoding. These methods demonstrate significant limitations in managing complex semantic relationships and achieving precise cross-modal alignment, largely due to their coupled processing mechanism that conflates target localization with boundary delineation. This architectural coupling amplifies error propagation under semantic ambiguity while restricting model generalizability and interpretability. To address these issues, we propose RSRefSeg 2, a decoupling paradigm that reformulates the conventional workflow into a collaborative dual-stage framework: coarse localization followed by fine segmentation. RSRefSeg 2 integrates CLIP's cross-modal alignment strength with SAM's segmentation generalizability through strategic foundation model collaboration. Specifically, CLIP is employed as the dual-modal encoder to activate target features within its pre-aligned semantic space and generate localization prompts. To mitigate CLIP's misactivation challenges in multi-entity scenarios described by referring texts, a cascaded second-order prompter is devised, which enhances precision through implicit reasoning via decomposition of text embeddings into complementary semantic subspaces. These optimized semantic prompts subsequently direct the SAM to generate pixel-level refined masks, thereby completing the semantic transmission pipeline. Extensive experiments (RefSegRS, RRSIS-D, and RISBench) demonstrate that RSRefSeg 2 surpasses contemporary methods in segmentation accuracy (+~3% gIoU) and complex semantic interpretation. Code is available at: https://github.com/KyanChen/RSRefSeg2.
The Segment Anything Model (SAM), with its prompt-driven paradigm, exhibits strong generalization in generic segmentation tasks. However, applying SAM to remote sensing (RS) images still faces two major challenges. First, manually constructing precise prompts for each image (e.g., points or boxes) is labor-intensive and inefficient, especially in RS scenarios with dense small objects or spatially fragmented distributions. Second, SAM lacks domain adaptability, as it is pre-trained primarily on natural images and struggles to capture RS-specific semantics and spatial characteristics, especially when segmenting novel or unseen classes. To address these issues, inspired by few-shot learning, we propose ViRefSAM, a novel framework that guides SAM utilizing only a few annotated reference images that contain class-specific objects. Without requiring manual prompts, ViRefSAM enables automatic segmentation of class-consistent objects across RS images. Specifically, ViRefSAM introduces two key components while keeping SAM's original architecture intact: (1) a Visual Contextual Prompt Encoder that extracts class-specific semantic clues from reference images and generates object-aware prompts via contextual interaction with target images; and (2) a Dynamic Target Alignment Adapter, integrated into SAM's image encoder, which mitigates the domain gap by injecting class-specific semantics into target image features, enabling SAM to dynamically focus on task-relevant regions. Extensive experiments on three few-shot segmentation benchmarks, including iSAID-5$^i$, LoveDA-2$^i$, and COCO-20$^i$, demonstrate that ViRefSAM enables accurate and automatic segmentation of unseen classes by leveraging only a few reference images and consistently outperforms existing few-shot segmentation methods across diverse datasets.
Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual annotation, which can be an expensive, time-consuming, and error-prone process. This signals a need for accurate, automatic, and annotation-efficient methods of training these models. We propose ADA-SAM (automated, domain-specific, and adaptive segment anything model), a novel multitask learning framework for medical image segmentation that leverages class activation maps from an auxiliary classifier to guide the predictions of the semi-supervised segmentation branch, which is based on the Segment Anything (SAM) framework. Additionally, our ADA-SAM model employs a novel gradient feedback mechanism to create a learnable connection between the segmentation and classification branches by using the segmentation gradients to guide and improve the classification predictions. We validate ADA-SAM on real-world clinical data collected during rehabilitation trials, and demonstrate that our proposed method outperforms both fully-supervised and semi-supervised baselines by double digits in limited label settings. Our code is available at: https://github.com/tbwa233/ADA-SAM.
Polyp segmentation in colonoscopy images is crucial for early detection and diagnosis of colorectal cancer. However, this task remains a significant challenge due to the substantial variations in polyp shape, size, and color, as well as the high similarity between polyps and surrounding tissues, often compounded by indistinct boundaries. While existing encoder-decoder CNN and transformer-based approaches have shown promising results, they struggle with stable segmentation performance on polyps with weak or blurry boundaries. These methods exhibit limited abilities to distinguish between polyps and non-polyps and capture essential boundary cues. Moreover, their generalizability still falls short of meeting the demands of real-time clinical applications. To address these limitations, we propose SAM-MaGuP, a groundbreaking approach for robust polyp segmentation. By incorporating a boundary distillation module and a 1D-2D Mamba adapter within the Segment Anything Model (SAM), SAM-MaGuP excels at resolving weak boundary challenges and amplifies feature learning through enriched global contextual interactions. Extensive evaluations across five diverse datasets reveal that SAM-MaGuP outperforms state-of-the-art methods, achieving unmatched segmentation accuracy and robustness. Our key innovations, a Mamba-guided boundary prior and a 1D-2D Mamba block, set a new benchmark in the field, pushing the boundaries of polyp segmentation to new heights.
Instance segmentation of novel objects instances in RGB images, given some example images for each object, is a well known problem in computer vision. Designing a model general enough to be employed, for all kinds of novel objects, without (re-) training, has proven to be a difficult task. To handle this, we propose a simple, yet powerful, framework, called: Novel Object Cyclic Threshold based Instance Segmentation (NOCTIS). This work stems from and improves upon previous ones like CNOS, SAM-6D and NIDS-Net; thus, it also leverages on recent vision foundation models, namely: Grounded-SAM 2 and DINOv2. It utilises Grounded-SAM 2 to obtain object proposals with precise bounding boxes and their corresponding segmentation masks; while DINOv2's zero-shot capabilities are employed to generate the image embeddings. The quality of those masks, together with their embeddings, is of vital importance to our approach; as the proposal-object matching is realized by determining an object matching score based on the similarity of the class embeddings and the average maximum similarity of the patch embeddings. Differently to SAM-6D, calculating the latter involves a prior patch filtering based on the distance between each patch and its corresponding cyclic/roundtrip patch in the image grid. Furthermore, the average confidence of the proposals' bounding box and mask is used as an additional weighting factor for the object matching score. We empirically show that NOCTIS, without further training/fine tuning, outperforms the best RGB and RGB-D methods on the seven core datasets of the BOP 2023 challenge for the "Model-based 2D segmentation of unseen objects" task.
Accurate and generalizable object segmentation in ultrasound imaging remains a significant challenge due to anatomical variability, diverse imaging protocols, and limited annotated data. In this study, we propose a prompt-driven vision-language model (VLM) that integrates Grounding DINO with SAM2 to enable object segmentation across multiple ultrasound organs. A total of 18 public ultrasound datasets, encompassing the breast, thyroid, liver, prostate, kidney, and paraspinal muscle, were utilized. These datasets were divided into 15 for fine-tuning and validation of Grounding DINO using Low Rank Adaptation (LoRA) to the ultrasound domain, and 3 were held out entirely for testing to evaluate performance in unseen distributions. Comprehensive experiments demonstrate that our approach outperforms state-of-the-art segmentation methods, including UniverSeg, MedSAM, MedCLIP-SAM, BiomedParse, and SAMUS on most seen datasets while maintaining strong performance on unseen datasets without additional fine-tuning. These results underscore the promise of VLMs in scalable and robust ultrasound image analysis, reducing dependence on large, organ-specific annotated datasets. We will publish our code on code.sonography.ai after acceptance.
Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges, synthetic medical data generation offers a promising solution. Generative AI (GenAI), employing generative deep learning models, has proven effective at producing realistic synthetic images. This study proposes a novel mask-guided GenAI approach using diffusion models to generate synthetic fetal head ultrasound images paired with segmentation masks. These synthetic pairs augment real datasets for supervised fine-tuning of the Segment Anything Model (SAM). Our results show that the synthetic data captures real image features effectively, and this approach reaches state-of-the-art fetal head segmentation, especially when trained with a limited number of real image-mask pairs. In particular, the segmentation reaches Dice Scores of 94.66\% and 94.38\% using a handful of ultrasound images from the Spanish and African cohorts, respectively. Our code, models, and data are available on GitHub.
Existing video segmenter and grounder approaches, exemplified by Sa2VA, directly fuse features within segmentation models. This often results in an undesirable entanglement of dynamic visual information and static semantics, thereby degrading segmentation accuracy. To systematically mitigate this issue, we propose DeSa2VA, a decoupling-enhanced prompting scheme integrating text pre-training and a linear decoupling module to address the information processing limitations inherent in SAM-2. Specifically, first, we devise a pre-training paradigm that converts textual ground-truth labels into point-level prompts while generating corresponding text masks. These masks are refined through a hybrid loss function to strengthen the model's semantic grounding capabilities. Next, we employ linear projection to disentangle hidden states that generated by a large language model into distinct textual and visual feature subspaces. Finally, a dynamic mask fusion strategy synergistically combines these decoupled features through triple supervision from predicted text/visual masks and ground-truth annotations. Extensive experiments demonstrate state-of-the-art performance across diverse tasks, including image segmentation, image question answering, video segmentation, and video question answering. Our codes are available at https://github.com/longmalongma/DeSa2VA.
Text-to-image retrieval (TIR) aims to find relevant images based on a textual query, but existing approaches are primarily based on whole-image captions and lack interpretability. Meanwhile, referring expression segmentation (RES) enables precise object localization based on natural language descriptions but is computationally expensive when applied across large image collections. To bridge this gap, we introduce Mask-aware TIR (MaTIR), a new task that unifies TIR and RES, requiring both efficient image search and accurate object segmentation. To address this task, we propose a two-stage framework, comprising a first stage for segmentation-aware image retrieval and a second stage for reranking and object grounding with a multimodal large language model (MLLM). We leverage SAM 2 to generate object masks and Alpha-CLIP to extract region-level embeddings offline at first, enabling effective and scalable online retrieval. Secondly, MLLM is used to refine retrieval rankings and generate bounding boxes, which are matched to segmentation masks. We evaluate our approach on COCO and D$^3$ datasets, demonstrating significant improvements in both retrieval accuracy and segmentation quality over previous methods.
Video Instance Segmentation (VIS) fundamentally struggles with pervasive challenges including object occlusions, motion blur, and appearance variations during temporal association. To overcome these limitations, this work introduces geometric awareness to enhance VIS robustness by strategically leveraging monocular depth estimation. We systematically investigate three distinct integration paradigms. Expanding Depth Channel (EDC) method concatenates the depth map as input channel to segmentation networks; Sharing ViT (SV) designs a uniform ViT backbone, shared between depth estimation and segmentation branches; Depth Supervision (DS) makes use of depth prediction as an auxiliary training guide for feature learning. Though DS exhibits limited effectiveness, benchmark evaluations demonstrate that EDC and SV significantly enhance the robustness of VIS. When with Swin-L backbone, our EDC method gets 56.2 AP, which sets a new state-of-the-art result on OVIS benchmark. This work conclusively establishes depth cues as critical enablers for robust video understanding.
Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data, poses major challenges for automated segmentation. To address this, we propose Color-Structure Dual-Student (CSDS), a novel semi-supervised segmentation framework designed to learn disentangled representations of stain appearance and tissue structure. CSDS comprises two specialized student networks: one trained on stain-augmented inputs to model chromatic variation, and the other on structure-augmented inputs to capture morphological cues. A shared teacher network, updated via Exponential Moving Average (EMA), supervises both students through pseudo-labels. To further improve label reliability, we introduce stain-aware and structure-aware uncertainty estimation modules that adaptively modulate the contribution of each student during training. Experiments on the GlaS and CRAG datasets show that CSDS achieves state-of-the-art performance in low-label settings, with Dice score improvements of up to 1.2% on GlaS and 0.7% on CRAG at 5% labeled data, and 0.7% and 1.4% at 10%. Our code and pre-trained models are available at https://github.com/hieuphamha19/CSDS.
The performance of image segmentation models has historically been constrained by the high cost of collecting large-scale annotated data. The Segment Anything Model (SAM) alleviates this original problem through a promptable, semantics-agnostic, segmentation paradigm and yet still requires manual visual-prompts or complex domain-dependent prompt-generation rules to process a new image. Towards reducing this new burden, our work investigates the task of object segmentation when provided with, alternatively, only a small set of reference images. Our key insight is to leverage strong semantic priors, as learned by foundation models, to identify corresponding regions between a reference and a target image. We find that correspondences enable automatic generation of instance-level segmentation masks for downstream tasks and instantiate our ideas via a multi-stage, training-free method incorporating (1) memory bank construction; (2) representation aggregation and (3) semantic-aware feature matching. Our experiments show significant improvements on segmentation metrics, leading to state-of-the-art performance on COCO FSOD (36.8% nAP), PASCAL VOC Few-Shot (71.2% nAP50) and outperforming existing training-free approaches on the Cross-Domain FSOD benchmark (22.4% nAP).