Counterfactual explanations play a pivotal role in explainable artificial intelligence (XAI) by offering intuitive, human-understandable alternatives that elucidate machine learning model decisions. Despite their significance, existing methods for generating counterfactuals often require constant access to the predictive model, involve computationally intensive optimization for each instance and lack the flexibility to adapt to new user-defined constraints without retraining. In this paper, we propose DiCoFlex, a novel model-agnostic, conditional generative framework that produces multiple diverse counterfactuals in a single forward pass. Leveraging conditional normalizing flows trained solely on labeled data, DiCoFlex addresses key limitations by enabling real-time user-driven customization of constraints such as sparsity and actionability at inference time. Extensive experiments on standard benchmark datasets show that DiCoFlex outperforms existing methods in terms of validity, diversity, proximity, and constraint adherence, making it a practical and scalable solution for counterfactual generation in sensitive decision-making domains.
Artificial Intelligence (AI) is one of the major technological advancements of this century, bearing incredible potential for users through AI-powered applications and tools in numerous domains. Being often black-box (i.e., its decision-making process is unintelligible), developers typically resort to eXplainable Artificial Intelligence (XAI) techniques to interpret the behaviour of AI models to produce systems that are transparent, fair, reliable, and trustworthy. However, presenting explanations to the user is not trivial and is often left as a secondary aspect of the system's design process, leading to AI systems that are not useful to end-users. This paper presents a Systematic Literature Review on Explanation User Interfaces (XUIs) to gain a deeper understanding of the solutions and design guidelines employed in the academic literature to effectively present explanations to users. To improve the contribution and real-world impact of this survey, we also present a framework for Human-cEnteRed developMent of Explainable user interfaceS (HERMES) to guide practitioners and academics in the design and evaluation of XUIs.
Psychiatric disorders affect millions globally, yet their diagnosis faces significant challenges in clinical practice due to subjective assessments and accessibility concerns, leading to potential delays in treatment. To help address this issue, we present Heart2Mind, a human-centered contestable psychiatric disorder diagnosis system using wearable electrocardiogram (ECG) monitors. Our approach leverages cardiac biomarkers, particularly heart rate variability (HRV) and R-R intervals (RRI) time series, as objective indicators of autonomic dysfunction in psychiatric conditions. The system comprises three key components: (1) a Cardiac Monitoring Interface (CMI) for real-time data acquisition from Polar H9/H10 devices; (2) a Multi-Scale Temporal-Frequency Transformer (MSTFT) that processes RRI time series through integrated time-frequency domain analysis; (3) a Contestable Diagnosis Interface (CDI) combining Self-Adversarial Explanations (SAEs) with contestable Large Language Models (LLMs). Our MSTFT achieves 91.7% accuracy on the HRV-ACC dataset using leave-one-out cross-validation, outperforming state-of-the-art methods. SAEs successfully detect inconsistencies in model predictions by comparing attention-based and gradient-based explanations, while LLMs enable clinicians to validate correct predictions and contest erroneous ones. This work demonstrates the feasibility of combining wearable technology with Explainable Artificial Intelligence (XAI) and contestable LLMs to create a transparent, contestable system for psychiatric diagnosis that maintains clinical oversight while leveraging advanced AI capabilities. Our implementation is publicly available at: https://github.com/Analytics-Everywhere-Lab/heart2mind.
While Graph Neural Networks (GNNs) have become the de facto model for learning from structured data, their decisional process remains opaque to the end user, undermining their deployment in safety-critical applications. In the case of graph classification, Explainable Artificial Intelligence (XAI) techniques address this major issue by identifying sub-graph motifs that explain predictions. However, advancements in this field are hindered by a chronic scarcity of benchmark datasets with known ground-truth motifs to assess the explanations' quality. Current graph XAI benchmarks are limited to synthetic data or a handful of real-world tasks hand-curated by domain experts. In this paper, we propose a general method to automate the construction of XAI benchmarks for graph classification from real-world datasets. We provide both 15 ready-made benchmarks, as well as the code to generate more than 2000 additional XAI benchmarks with our method. As a use case, we employ our benchmarks to assess the effectiveness of some popular graph explainers.
Counterfactuals play a pivotal role in the two distinct data science fields of causal inference (CI) and explainable artificial intelligence (XAI). While the core idea behind counterfactuals remains the same in both fields--the examination of what would have happened under different circumstances--there are key differences in how they are used and interpreted. We introduce a formal definition that encompasses the multi-faceted concept of the counterfactual in CI and XAI. We then discuss how counterfactuals are used, evaluated, generated, and operationalized in CI vs. XAI, highlighting conceptual and practical differences. By comparing and contrasting the two, we hope to identify opportunities for cross-fertilization across CI and XAI.
Explainable Artificial Intelligence (XAI) is critical for attaining trust in the operation of AI systems. A key question of an AI system is ``why was this decision made this way''. Formal approaches to XAI use a formal model of the AI system to identify abductive explanations. While abductive explanations may be applicable to a large number of inputs sharing the same concrete values, more general explanations may be preferred for numeric inputs. So-called inflated abductive explanations give intervals for each feature ensuring that any input whose values fall withing these intervals is still guaranteed to make the same prediction. Inflated explanations cover a larger portion of the input space, and hence are deemed more general explanations. But there can be many (inflated) abductive explanations for an instance. Which is the best? In this paper, we show how to find a most general abductive explanation for an AI decision. This explanation covers as much of the input space as possible, while still being a correct formal explanation of the model's behaviour. Given that we only want to give a human one explanation for a decision, the most general explanation gives us the explanation with the broadest applicability, and hence the one most likely to seem sensible. (The paper has been accepted at IJCAI2025 conference.)
Recently, post hoc explanation methods have emerged to enhance model transparency by attributing model outputs to input features. However, these methods face challenges due to their specificity to certain neural network architectures and data modalities. Existing explainable artificial intelligence (XAI) frameworks have attempted to address these challenges but suffer from several limitations. These include limited flexibility to diverse model architectures and data modalities due to hard-coded implementations, a restricted number of supported XAI methods because of the requirements for layer-specific operations of attribution methods, and sub-optimal recommendations of explanations due to the lack of evaluation and optimization phases. Consequently, these limitations impede the adoption of XAI technology in real-world applications, making it difficult for practitioners to select the optimal explanation method for their domain. To address these limitations, we introduce \textbf{PnPXAI}, a universal XAI framework that supports diverse data modalities and neural network models in a Plug-and-Play (PnP) manner. PnPXAI automatically detects model architectures, recommends applicable explanation methods, and optimizes hyperparameters for optimal explanations. We validate the framework's effectiveness through user surveys and showcase its versatility across various domains, including medicine and finance.
Traditional machine learning models often prioritize predictive accuracy, often at the expense of model transparency and interpretability. The lack of transparency makes it difficult for organizations to comply with regulatory requirements and gain stakeholders trust. In this research, we propose a fraud detection framework that combines a stacking ensemble of well-known gradient boosting models: XGBoost, LightGBM, and CatBoost. In addition, explainable artificial intelligence (XAI) techniques are used to enhance the transparency and interpretability of the model's decisions. We used SHAP (SHapley Additive Explanations) for feature selection to identify the most important features. Further efforts were made to explain the model's predictions using Local Interpretable Model-Agnostic Explanation (LIME), Partial Dependence Plots (PDP), and Permutation Feature Importance (PFI). The IEEE-CIS Fraud Detection dataset, which includes more than 590,000 real transaction records, was used to evaluate the proposed model. The model achieved a high performance with an accuracy of 99% and an AUC-ROC score of 0.99, outperforming several recent related approaches. These results indicate that combining high prediction accuracy with transparent interpretability is possible and could lead to a more ethical and trustworthy solution in financial fraud detection.
Despite the growing interest in Explainable Artificial Intelligence (XAI), explainability is rarely considered during hyperparameter tuning or neural architecture optimization, where the focus remains primarily on minimizing predictive loss. In this work, we introduce the novel concept of XAI consistency, defined as the agreement among different feature attribution methods, and propose new metrics to quantify it. For the first time, we integrate XAI consistency directly into the hyperparameter tuning objective, creating a multi-objective optimization framework that balances predictive performance with explanation robustness. Implemented within the Sequential Parameter Optimization Toolbox (SPOT), our approach uses both weighted aggregation and desirability-based strategies to guide model selection. Through our proposed framework and supporting tools, we explore the impact of incorporating XAI consistency into the optimization process. This enables us to characterize distinct regions in the architecture configuration space: one region with poor performance and comparatively low interpretability, another with strong predictive performance but weak interpretability due to low \gls{xai} consistency, and a trade-off region that balances both objectives by offering high interpretability alongside competitive performance. Beyond introducing this novel approach, our research provides a foundation for future investigations into whether models from the trade-off zone-balancing performance loss and XAI consistency-exhibit greater robustness by avoiding overfitting to training performance, thereby leading to more reliable predictions on out-of-distribution data.
Explainable artificial intelligence (XAI) is essential for trustworthy machine learning (ML), particularly in high-stakes domains such as healthcare and finance. Shapley value (SV) methods provide a principled framework for feature attribution in complex models but incur high computational costs, limiting their scalability in high-dimensional settings. We propose Stochastic Iterative Momentum for Shapley Value Approximation (SIM-Shapley), a stable and efficient SV approximation method inspired by stochastic optimization. We analyze variance theoretically, prove linear $Q$-convergence, and demonstrate improved empirical stability and low bias in practice on real-world datasets. In our numerical experiments, SIM-Shapley reduces computation time by up to 85% relative to state-of-the-art baselines while maintaining comparable feature attribution quality. Beyond feature attribution, our stochastic mini-batch iterative framework extends naturally to a broader class of sample average approximation problems, offering a new avenue for improving computational efficiency with stability guarantees. Code is publicly available at https://github.com/nliulab/SIM-Shapley.
Artificial Intelligence (AI) is rapidly expanding and integrating more into daily life to automate tasks, guide decision making, and enhance efficiency. However, complex AI models, which make decisions without providing clear explanations (known as the "black-box problem"), currently restrict trust and widespread adoption of AI. Explainable Artificial Intelligence (XAI) has emerged to address the black-box problem of making AI systems more interpretable and transparent so stakeholders can trust, verify, and act upon AI-based outcomes. Researchers have developed various techniques to foster XAI in the Software Development Lifecycle. However, there are gaps in applying XAI techniques in the Software Engineering phases. Literature review shows that 68% of XAI in Software Engineering research is focused on maintenance as opposed to 8% on software management and requirements. In this paper, we present a comprehensive survey of the applications of XAI methods such as concept-based explanations, Local Interpretable Model-agnostic Explanations (LIME), SHapley Additive exPlanations (SHAP), rule extraction, attention mechanisms, counterfactual explanations, and example-based explanations to the different phases of the Software Development Life Cycle (SDLC), including requirements elicitation, design and development, testing and deployment, and evolution. To the best of our knowledge, this paper presents the first comprehensive survey of XAI techniques for every phase of the Software Development Life Cycle (SDLC). This survey aims to promote explainable AI in Software Engineering and facilitate the practical application of complex AI models in AI-driven software development.
Concept-based explanations have emerged as an effective approach within Explainable Artificial Intelligence, enabling interpretable insights by aligning model decisions with human-understandable concepts. However, existing methods rely on computationally intensive procedures and struggle to efficiently capture complex, semantic concepts. Recently, the Concept Discovery through Latent Diffusion-based Counterfactual Trajectories (CDCT) framework, introduced by Varshney et al. (2025), attempts to identify concepts via dimension-wise traversal of the latent space of a Variational Autoencoder trained on counterfactual trajectories. Extending the CDCT framework, this work introduces Concept Directions via Latent Clustering (CDLC), which extracts global, class-specific concept directions by clustering latent difference vectors derived from factual and diffusion-generated counterfactual image pairs. CDLC substantially reduces computational complexity by eliminating the exhaustive latent dimension traversal required in CDCT and enables the extraction of multidimensional semantic concepts encoded across the latent dimensions. This approach is validated on a real-world skin lesion dataset, demonstrating that the extracted concept directions align with clinically recognized dermoscopic features and, in some cases, reveal dataset-specific biases or unknown biomarkers. These results highlight that CDLC is interpretable, scalable, and applicable across high-stakes domains and diverse data modalities.
The present research tackles the difficulty of predicting osteoporosis risk via machine learning (ML) approaches, emphasizing the use of explainable artificial intelligence (XAI) to improve model transparency. Osteoporosis is a significant public health concern, sometimes remaining untreated owing to its asymptomatic characteristics, and early identification is essential to avert fractures. The research assesses six machine learning classifiers: Random Forest, Logistic Regression, XGBoost, AdaBoost, LightGBM, and Gradient Boosting and utilizes a dataset based on clinical, demographic, and lifestyle variables. The models are refined using GridSearchCV to calibrate hyperparameters, with the objective of enhancing predictive efficacy. XGBoost had the greatest accuracy (91%) among the evaluated models, surpassing others in precision (0.92), recall (0.91), and F1-score (0.90). The research further integrates XAI approaches, such as SHAP, LIME, and Permutation Feature Importance, to elucidate the decision-making process of the optimal model. The study indicates that age is the primary determinant in forecasting osteoporosis risk, followed by hormonal alterations and familial history. These results corroborate clinical knowledge and affirm the models' therapeutic significance. The research underscores the significance of explainability in machine learning models for healthcare applications, guaranteeing that physicians can rely on the system's predictions. The report ultimately proposes directions for further research, such as validation across varied populations and the integration of supplementary biomarkers for enhanced predictive accuracy.
This chapter discusses the opportunities of eXplainable Artificial Intelligence (XAI) within the realm of spatial analysis. A key objective in spatial analysis is to model spatial relationships and infer spatial processes to generate knowledge from spatial data, which has been largely based on spatial statistical methods. More recently, machine learning offers scalable and flexible approaches that complement traditional methods and has been increasingly applied in spatial data science. Despite its advantages, machine learning is often criticized for being a black box, which limits our understanding of model behavior and output. Recognizing this limitation, XAI has emerged as a pivotal field in AI that provides methods to explain the output of machine learning models to enhance transparency and understanding. These methods are crucial for model diagnosis, bias detection, and ensuring the reliability of results obtained from machine learning models. This chapter introduces key concepts and methods in XAI with a focus on Shapley value-based approaches, which is arguably the most popular XAI method, and their integration with spatial analysis. An empirical example of county-level voting behaviors in the 2020 Presidential election is presented to demonstrate the use of Shapley values and spatial analysis with a comparison to multi-scale geographically weighted regression. The chapter concludes with a discussion on the challenges and limitations of current XAI techniques and proposes new directions.
Explainable artificial intelligence (XAI) has become increasingly important in decision-critical domains such as healthcare, finance, and law. Counterfactual (CF) explanations, a key approach in XAI, provide users with actionable insights by suggesting minimal modifications to input features that lead to different model outcomes. Despite significant advancements, existing CF generation methods often struggle to balance proximity, diversity, and robustness, limiting their real-world applicability. A widely adopted framework, Diverse Counterfactual Explanations (DiCE), emphasizes diversity but lacks robustness, making CF explanations sensitive to perturbations and domain constraints. To address these challenges, we introduce DiCE-Extended, an enhanced CF explanation framework that integrates multi-objective optimization techniques to improve robustness while maintaining interpretability. Our approach introduces a novel robustness metric based on the Dice-Sorensen coefficient, ensuring stability under small input variations. Additionally, we refine CF generation using weighted loss components (lambda_p, lambda_d, lambda_r) to balance proximity, diversity, and robustness. We empirically validate DiCE-Extended on benchmark datasets (COMPAS, Lending Club, German Credit, Adult Income) across multiple ML backends (Scikit-learn, PyTorch, TensorFlow). Results demonstrate improved CF validity, stability, and alignment with decision boundaries compared to standard DiCE-generated explanations. Our findings highlight the potential of DiCE-Extended in generating more reliable and interpretable CFs for high-stakes applications. Future work will explore adaptive optimization techniques and domain-specific constraints to further enhance CF generation in real-world scenarios.
This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy. Due to the limitations of existing radiomics and unimodal deep learning approaches, we introduce an intermediate fusion strategy that integrates imaging and clinical data, enabling efficient interaction between data modalities. The proposed Multimodal Doctor-in-the-Loop method further enhances clinical relevance by embedding clinicians' domain knowledge directly into the training process, guiding the model's focus gradually from broader lung regions to specific lesions. Results demonstrate improved predictive accuracy and explainability, providing insights into optimal data integration strategies for clinical applications.
Large Language Models are fundamental actors in the modern IT landscape dominated by AI solutions. However, security threats associated with them might prevent their reliable adoption in critical application scenarios such as government organizations and medical institutions. For this reason, commercial LLMs typically undergo a sophisticated censoring mechanism to eliminate any harmful output they could possibly produce. In response to this, LLM Jailbreaking is a significant threat to such protections, and many previous approaches have already demonstrated its effectiveness across diverse domains. Existing jailbreak proposals mostly adopt a generate-and-test strategy to craft malicious input. To improve the comprehension of censoring mechanisms and design a targeted jailbreak attack, we propose an Explainable-AI solution that comparatively analyzes the behavior of censored and uncensored models to derive unique exploitable alignment patterns. Then, we propose XBreaking, a novel jailbreak attack that exploits these unique patterns to break the security constraints of LLMs by targeted noise injection. Our thorough experimental campaign returns important insights about the censoring mechanisms and demonstrates the effectiveness and performance of our attack.
Explainable Artificial Intelligence (XAI) has emerged as a pillar of Trustworthy AI and aims to bring transparency in complex models that are opaque by nature. Despite the benefits of incorporating explanations in models, an urgent need is found in addressing the privacy concerns of providing this additional information to end users. In this article, we conduct a scoping review of existing literature to elicit details on the conflict between privacy and explainability. Using the standard methodology for scoping review, we extracted 57 articles from 1,943 studies published from January 2019 to December 2024. The review addresses 3 research questions to present readers with more understanding of the topic: (1) what are the privacy risks of releasing explanations in AI systems? (2) what current methods have researchers employed to achieve privacy preservation in XAI systems? (3) what constitutes a privacy preserving explanation? Based on the knowledge synthesized from the selected studies, we categorize the privacy risks and preservation methods in XAI and propose the characteristics of privacy preserving explanations to aid researchers and practitioners in understanding the requirements of XAI that is privacy compliant. Lastly, we identify the challenges in balancing privacy with other system desiderata and provide recommendations for achieving privacy preserving XAI. We expect that this review will shed light on the complex relationship of privacy and explainability, both being the fundamental principles of Trustworthy AI.
Explainable artificial intelligence (XAI) enhances AI system transparency by framing interpretability as an optimization problem. However, this approach often necessitates numerous iterations of computationally intensive operations, limiting its applicability in real-time scenarios. While recent research has focused on XAI hardware acceleration on FPGAs and TPU, these methods do not fully address energy efficiency in real-time settings. To address this limitation, we propose XAIedge, a novel framework that leverages approximate computing techniques into XAI algorithms, including integrated gradients, model distillation, and Shapley analysis. XAIedge translates these algorithms into approximate matrix computations and exploits the synergy between convolution, Fourier transform, and approximate computing paradigms. This approach enables efficient hardware acceleration on TPU-based edge devices, facilitating faster real-time outcome interpretations. Our comprehensive evaluation demonstrates that XAIedge achieves a $2\times$ improvement in energy efficiency compared to existing accurate XAI hardware acceleration techniques while maintaining comparable accuracy. These results highlight the potential of XAIedge to significantly advance the deployment of explainable AI in energy-constrained real-time applications.
In this paper, we propose a new adversarial training framework to address high-dimensional instantaneous channel estimation in wireless communications. Specifically, we train a generative adversarial network to predict a channel realization in the time-frequency-space domain, in which the generator exploits the third-order moment of the input in its loss function and applies a new reparameterization method for latent distribution learning to minimize the Wasserstein distance between the true and estimated channel distributions. Next, we propose an explainable artificial intelligence mechanism to examine how the critic discriminates the generated channel. We demonstrate that our proposed framework is superior to existing methods in terms of minimizing estimation errors. Additionally, we find that the critic's attention focuses on the high-power portion of the channel's time-frequency representation.