This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we propose a cascaded binary classification framework that fine-tunes pre-trained language models and incorporates pause encoding to better capture disfluencies. This design streamlines multi-class classification and addresses class imbalance by restructuring the decision process. For the Mini-Mental State Examination score regression task, we develop an enhanced multimodal fusion system that combines diverse acoustic and linguistic features. Separate regression models are trained on individual feature sets, with ensemble learning applied through score averaging. Experimental results on the test set outperform the baselines provided by the organizers in both tasks, demonstrating the robustness and effectiveness of our approach.
Peptide compounds demonstrate considerable potential as therapeutic agents due to their high target affinity and low toxicity, yet their drug development is constrained by their low membrane permeability. Molecular weight and peptide length have significant effects on the logD of peptides, which in turn influences their ability to cross biological membranes. However, accurate prediction of peptide logD remains challenging due to the complex interplay between sequence, structure, and ionization states. This study introduces LengthLogD, a predictive framework that establishes specialized models through molecular length stratification while innovatively integrating multi-scale molecular representations. We constructed feature spaces across three hierarchical levels: atomic (10 molecular descriptors), structural (1024-bit Morgan fingerprints), and topological (3 graph-based features including Wiener index), optimized through stratified ensemble learning. An adaptive weight allocation mechanism specifically developed for long peptides significantly enhances model generalizability. Experimental results demonstrate superior performance across all categories: short peptides (R^2=0.855), medium peptides (R^2=0.816), and long peptides (R^2=0.882), with a 34.7% reduction in prediction error for long peptides compared to conventional single-model approaches. Ablation studies confirm: 1) The length-stratified strategy contributes 41.2% to performance improvement; 2) Topological features account for 28.5% of predictive importance. Compared to state-of-the-art models, our method maintains short peptide prediction accuracy while achieving a 25.7% increase in the coefficient of determination (R^2) for long peptides. This research provides a precise logD prediction tool for peptide drug development, particularly demonstrating unique value in optimizing long peptide lead compounds.
Exploring the trustworthiness of deep learning models is crucial, especially in critical domains such as medical imaging decision support systems. Conformal prediction has emerged as a rigorous means of providing deep learning models with reliable uncertainty estimates and safety guarantees. However, conformal prediction results face challenges due to the backbone model's struggles in domain-shifted scenarios, such as variations in different sources. To aim this challenge, this paper proposes a novel framework termed Conformal Ensemble of Vision Transformers (CE-ViTs) designed to enhance image classification performance by prioritizing domain adaptation and model robustness, while accounting for uncertainty. The proposed method leverages an ensemble of vision transformer models in the backbone, trained on diverse datasets including HAM10000, Dermofit, and Skin Cancer ISIC datasets. This ensemble learning approach, calibrated through the combined mentioned datasets, aims to enhance domain adaptation through conformal learning. Experimental results underscore that the framework achieves a high coverage rate of 90.38\%, representing an improvement of 9.95\% compared to the HAM10000 model. This indicates a strong likelihood that the prediction set includes the true label compared to singular models. Ensemble learning in CE-ViTs significantly improves conformal prediction performance, increasing the average prediction set size for challenging misclassified samples from 1.86 to 3.075.
We revisit the classical problem of Bayesian ensembles and address the challenge of learning optimal combinations of Bayesian models in an online, continual learning setting. To this end, we reinterpret existing approaches such as Bayesian model averaging (BMA) and Bayesian stacking through a novel empirical Bayes lens, shedding new light on the limitations and pathologies of BMA. Further motivated by insights from online optimization, we propose Online Bayesian Stacking (OBS), a method that optimizes the log-score over predictive distributions to adaptively combine Bayesian models. A key contribution of our work is establishing a novel connection between OBS and portfolio selection, bridging Bayesian ensemble learning with a rich, well-studied theoretical framework that offers efficient algorithms and extensive regret analysis. We further clarify the relationship between OBS and online BMA, showing that they optimize related but distinct cost functions. Through theoretical analysis and empirical evaluation, we identify scenarios where OBS outperforms online BMA and provide principled guidance on when practitioners should prefer one approach over the other.
Bootstrap methods have long been a cornerstone of ensemble learning in machine learning. This paper presents a theoretical analysis of bootstrap techniques applied to the Least Square Support Vector Machine (LSSVM) ensemble in the context of large and growing sample sizes and feature dimensionalities. Leveraging tools from Random Matrix Theory, we investigate the performance of this classifier that aggregates decision functions from multiple weak classifiers, each trained on different subsets of the data. We provide insights into the use of bootstrap methods in high-dimensional settings, enhancing our understanding of their impact. Based on these findings, we propose strategies to select the number of subsets and the regularization parameter that maximize the performance of the LSSVM. Empirical experiments on synthetic and real-world datasets validate our theoretical results.
Mixture of Experts (MoE) models constitute a widely utilized class of ensemble learning approaches in statistics and machine learning, known for their flexibility and computational efficiency. They have become integral components in numerous state-of-the-art deep neural network architectures, particularly for analyzing heterogeneous data across diverse domains. Despite their practical success, the theoretical understanding of model selection, especially concerning the optimal number of mixture components or experts, remains limited and poses significant challenges. These challenges primarily stem from the inclusion of covariates in both the Gaussian gating functions and expert networks, which introduces intrinsic interactions governed by partial differential equations with respect to their parameters. In this paper, we revisit the concept of dendrograms of mixing measures and introduce a novel extension to Gaussian-gated Gaussian MoE models that enables consistent estimation of the true number of mixture components and achieves the pointwise optimal convergence rate for parameter estimation in overfitted scenarios. Notably, this approach circumvents the need to train and compare a range of models with varying numbers of components, thereby alleviating the computational burden, particularly in high-dimensional or deep neural network settings. Experimental results on synthetic data demonstrate the effectiveness of the proposed method in accurately recovering the number of experts. It outperforms common criteria such as the Akaike information criterion, the Bayesian information criterion, and the integrated completed likelihood, while achieving optimal convergence rates for parameter estimation and accurately approximating the regression function.
The automatic diagnosis of chest diseases is a popular and challenging task. Most current methods are based on convolutional neural networks (CNNs), which focus on local features while neglecting global features. Recently, self-attention mechanisms have been introduced into the field of computer vision, demonstrating superior performance. Therefore, this paper proposes an effective model, CheX-DS, for classifying long-tail multi-label data in the medical field of chest X-rays. The model is based on the excellent CNN model DenseNet for medical imaging and the newly popular Swin Transformer model, utilizing ensemble deep learning techniques to combine the two models and leverage the advantages of both CNNs and Transformers. The loss function of CheX-DS combines weighted binary cross-entropy loss with asymmetric loss, effectively addressing the issue of data imbalance. The NIH ChestX-ray14 dataset is selected to evaluate the model's effectiveness. The model outperforms previous studies with an excellent average AUC score of 83.76\%, demonstrating its superior performance.
The management of chronic Heart Failure (HF) presents significant challenges in modern healthcare, requiring continuous monitoring, early detection of exacerbations, and personalized treatment strategies. In this paper, we present a predictive model founded on Machine Learning (ML) techniques to identify patients at HF risk. This model is an ensemble learning approach, a modified stacking technique, that uses two specialized models leveraging clinical and echocardiographic features and then a meta-model to combine the predictions of these two models. We initially assess the model on a real dataset and the obtained results suggest that it performs well in the stratification of patients at HR risk. Specifically, we obtained high sensitivity (95\%), ensuring that nearly all high-risk patients are identified. As for accuracy, we obtained 84\%, which can be considered moderate in some ML contexts. However, it is acceptable given our priority of identifying patients at risk of HF because they will be asked to participate in the telemonitoring program of the PrediHealth research project on which some of the authors of this paper are working. The initial findings also suggest that ML-based risk stratification models can serve as valuable decision-support tools not only in the PrediHealth project but also for healthcare professionals, aiding in early intervention and personalized patient management. To have a better understanding of the value and of potentiality of our predictive model, we also contrasted its results with those obtained by using three baseline models. The preliminary results indicate that our predictive model outperforms these baselines that flatly consider features, \ie not grouping them in clinical and echocardiographic features.
The rapid expansion of bike-sharing systems (BSS) has greatly improved urban "last-mile" connectivity, yet large-scale deployments face escalating operational challenges, particularly in detecting faulty bikes. Existing detection approaches either rely on static model-based thresholds that overlook dynamic spatiotemporal (ST) usage patterns or employ supervised learning methods that struggle with label scarcity and class imbalance. To address these limitations, this paper proposes a novel Self-Supervised Transformer (SSTransformer) framework for automatically detecting unusable shared bikes, leveraging ST features extracted from GPS trajectories and trip records. The model incorporates a self-supervised pre-training strategy to enhance its feature extraction capabilities, followed by fine-tuning for efficient status recognition. In the pre-training phase, the Transformer encoder learns generalized representations of bike movement via a self-supervised objective; in the fine-tuning phase, the encoder is adapted to a downstream binary classification task. Comprehensive experiments on a real-world dataset of 10,730 bikes (1,870 unusable, 8,860 normal) from Chengdu, China, demonstrate that SSTransformer significantly outperforms traditional machine learning, ensemble learning, and deep learning baselines, achieving the best accuracy (97.81%), precision (0.8889), and F1-score (0.9358). This work highlights the effectiveness of self-supervised Transformer on ST data for capturing complex anomalies in BSS, paving the way toward more reliable and scalable maintenance solutions for shared mobility.
In biomedical science, a set of objects or persons can often be described by multiple distinct sets of features obtained from different data sources or modalities (called "multi-view data"). Classical machine learning methods ignore the multi-view structure of such data, limiting model interpretability and performance. The R package `mvs` provides methods that were designed specifically for dealing with multi-view data, based on the multi-view stacking (MVS) framework. MVS is a form of supervised (machine) learning used to train multi-view classification or prediction models. MVS works by training a learning algorithm on each view separately, estimating the predictive power of each view-specific model through cross-validation, and then using another learning algorithm to assign weights to the view-specific models based on their estimated predictions. MVS is a form of ensemble learning, dividing the large multi-view learning problem into smaller sub-problems. Most of these sub-problems can be solved in parallel, making it computationally attractive. Additionally, the number of features of the sub-problems is greatly reduced compared with the full multi-view learning problem. This makes MVS especially useful when the total number of features is larger than the number of observations (i.e., high-dimensional data). MVS can still be applied even if the sub-problems are themselves high-dimensional by adding suitable penalty terms to the learning algorithms. Furthermore, MVS can be used to automatically select the views which are most important for prediction. The R package `mvs` makes fitting MVS models, including such penalty terms, easily and openly accessible. `mvs` allows for the fitting of stacked models with any number of levels, with different penalty terms, different outcome distributions, and provides several options for missing data handling.
Carbon intensity (CI) measures the average carbon emissions generated per unit of electricity, making it a crucial metric for quantifying and managing the environmental impact. Accurate CI predictions are vital for minimizing carbon footprints, yet the state-of-the-art method (CarbonCast) falls short due to its inability to address regional variability and lack of adaptability. To address these limitations, we introduce EnsembleCI, an adaptive, end-to-end ensemble learning-based approach for CI forecasting. EnsembleCI combines weighted predictions from multiple sublearners, offering enhanced flexibility and regional adaptability. In evaluations across 11 regional grids, EnsembleCI consistently surpasses CarbonCast, achieving the lowest mean absolute percentage error (MAPE) in almost all grids and improving prediction accuracy by an average of 19.58%. While performance still varies across grids due to inherent regional diversity, EnsembleCI reduces variability and exhibits greater robustness in long-term forecasting compared to CarbonCast and identifies region-specific key features, underscoring its interpretability and practical relevance. These findings position EnsembleCI as a more accurate and reliable solution for CI forecasting. EnsembleCI source code and data used in this paper are available at https://github.com/emmayly/EnsembleCI.
Recent advances in reinforcement learning (RL) for large language model (LLM) fine-tuning show promise in addressing multi-objective tasks but still face significant challenges, including complex objective balancing, low training efficiency, poor scalability, and limited explainability. Leveraging ensemble learning principles, we introduce an Ensemble Multi-Objective RL (EMORL) framework that fine-tunes multiple models with individual objectives while optimizing their aggregation after the training to improve efficiency and flexibility. Our method is the first to aggregate the last hidden states of individual models, incorporating contextual information from multiple objectives. This approach is supported by a hierarchical grid search algorithm that identifies optimal weighted combinations. We evaluate EMORL on counselor reflection generation tasks, using text-scoring LLMs to evaluate the generations and provide rewards during RL fine-tuning. Through comprehensive experiments on the PAIR and Psych8k datasets, we demonstrate the advantages of EMORL against existing baselines: significantly lower and more stable training consumption ($17,529\pm 1,650$ data points and $6,573\pm 147.43$ seconds), improved scalability and explainability, and comparable performance across multiple objectives.
Graph Coloring Problem (GCP) is an NP-Hard vertex labeling problem in graphs such that no two adjacent vertices can have the same color. Large instances of GCP cannot be solved in reasonable execution times by exact algorithms. Therefore, soft computing approaches, such as metaheuristics, have proven to be very efficient for solving large instances of GCP. In this study, we propose a new island-parallel ensemble metaheuristic algorithm (PEM-Color) to solve large GCP instances. Ensemble learning is a new machine learning approach based on combining the output of multiple models instead of using a single one. We use Message Passing Interface (MPI) parallel computation libraries to combine recent state-of-the-art metaheuristics: Harris Hawk Optimization (HHO), Artificial Bee Colony (ABC), and Teaching Learning Based (TLBO) to improve the quality of their solutions further. To the best of our knowledge, this is the first study that combines metaheuristics and applies to the GCP using an ensemble approach. We conducted experiments on large graph instances from the well-known DIMACS benchmark using 64 processors and achieved significant improvements in execution times. The experiments also indicate an almost linear speed-up with a strong scalability potential. The solution quality of the instances is promising, as our algorithm outperforms 13 state-of-the-art algorithms.
This study presents an ensemble-based approach for cocoa pod disease classification by integrating transfer learning with three ensemble learning strategies: Bagging, Boosting, and Stacking. Pre-trained convolutional neural networks, including VGG16, VGG19, ResNet50, ResNet101, InceptionV3, and Xception, were fine-tuned and employed as base learners to detect three disease categories: Black Pod Rot, Pod Borer, and Healthy. A balanced dataset of 6,000 cocoa pod images was curated and augmented to ensure robustness against variations in lighting, orientation, and disease severity. The performance of each ensemble method was evaluated using accuracy, precision, recall, and F1-score. Experimental results show that Bagging consistently achieved superior classification performance with a test accuracy of 100%, outperforming Boosting (97%) and Stacking (92%). The findings confirm that combining transfer learning with ensemble techniques improves model generalization and reliability, making it a promising direction for precision agriculture and automated crop disease management.
Model merging is an effective strategy to merge multiple models for enhancing model performances, and more efficient than ensemble learning as it will not introduce extra computation into inference. However, limited research explores if the merging process can occur within one model and enhance the model's robustness, which is particularly critical in the medical image domain. In the paper, we are the first to propose in-model merging (InMerge), a novel approach that enhances the model's robustness by selectively merging similar convolutional kernels in the deep layers of a single convolutional neural network (CNN) during the training process for classification. We also analytically reveal important characteristics that affect how in-model merging should be performed, serving as an insightful reference for the community. We demonstrate the feasibility and effectiveness of this technique for different CNN architectures on 4 prevalent datasets. The proposed InMerge-trained model surpasses the typically-trained model by a substantial margin. The code will be made public.
White blood cell (WBC) classification assists in assessing immune health and diagnosing various diseases, yet manual classification is labor-intensive and prone to inconsistencies. Recent advancements in deep learning have shown promise over traditional methods; however, challenges such as data imbalance and the computational demands of modern technologies, such as Transformer-based models which do not scale well with input size, limit their practical application. This paper introduces a novel framework that leverages Mamba models integrated with ensemble learning to improve WBC classification. Mamba models, known for their linear complexity, provide a scalable alternative to Transformer-based approaches, making them suitable for deployment in resource-constrained environments. Additionally, we introduce a new WBC dataset, Chula-WBC-8, for benchmarking. Our approach not only validates the effectiveness of Mamba models in this domain but also demonstrates their potential to significantly enhance classification efficiency without compromising accuracy. The source code can be found at https://github.com/LewisClifton/Mamba-WBC-Classification.
Recommending items to users has long been a fundamental task, and studies have tried to improve it ever since. Most well-known models commonly employ representation learning to map users and items into a unified embedding space for matching assessment. These approaches have primary limitations, especially when dealing with explicit feedback and sparse data contexts. Two primary limitations are their proneness to overfitting and failure to incorporate epistemic uncertainty in predictions. To address these problems, we propose a novel Bayesian Deep Ensemble Collaborative Filtering method named BDECF. To improve model generalization and quality, we utilize Bayesian Neural Networks, which incorporate uncertainty within their weight parameters. In addition, we introduce a new interpretable non-linear matching approach for the user and item embeddings, leveraging the advantages of the attention mechanism. Furthermore, we endorse the implementation of an ensemble-based supermodel to generate more robust and reliable predictions, resulting in a more complete model. Empirical evaluation through extensive experiments and ablation studies across a range of publicly accessible real-world datasets with differing sparsity characteristics confirms our proposed method's effectiveness and the importance of its components.
While text-to-image (T2I) generation models have achieved remarkable progress in recent years, existing evaluation methodologies for vision-language alignment still struggle with the fine-grained semantic matching. Current approaches based on global similarity metrics often overlook critical token-level correspondences between textual descriptions and visual content. To this end, we present TokenFocus-VQA, a novel evaluation framework that leverages Large Vision-Language Models (LVLMs) through visual question answering (VQA) paradigm with position-specific probability optimization. Our key innovation lies in designing a token-aware loss function that selectively focuses on probability distributions at pre-defined vocabulary positions corresponding to crucial semantic elements, enabling precise measurement of fine-grained semantical alignment. The proposed framework further integrates ensemble learning techniques to aggregate multi-perspective assessments from diverse LVLMs architectures, thereby achieving further performance enhancement. Evaluated on the NTIRE 2025 T2I Quality Assessment Challenge Track 1, our TokenFocus-VQA ranks 2nd place (0.8445, only 0.0001 lower than the 1st method) on public evaluation and 2nd place (0.8426) on the official private test set, demonstrating superiority in capturing nuanced text-image correspondences compared to conventional evaluation methods.
Fault tolerance in Deep Neural Networks (DNNs) deployed on resource-constrained systems presents unique challenges for high-accuracy applications with strict timing requirements. Memory bit-flips can severely degrade DNN accuracy, while traditional protection approaches like Triple Modular Redundancy (TMR) often sacrifice accuracy to maintain reliability, creating a three-way dilemma between reliability, accuracy, and timeliness. We introduce NAPER, a novel protection approach that addresses this challenge through ensemble learning. Unlike conventional redundancy methods, NAPER employs heterogeneous model redundancy, where diverse models collectively achieve higher accuracy than any individual model. This is complemented by an efficient fault detection mechanism and a real-time scheduler that prioritizes meeting deadlines by intelligently scheduling recovery operations without interrupting inference. Our evaluations demonstrate NAPER's superiority: 40% faster inference in both normal and fault conditions, maintained accuracy 4.2% higher than TMR-based strategies, and guaranteed uninterrupted operation even during fault recovery. NAPER effectively balances the competing demands of accuracy, reliability, and timeliness in real-time DNN applications
Generative models, such as GPT and BERT, have significantly improved performance in tasks like text generation and summarization. However, hallucinations "where models generate non-factual or misleading content" are especially problematic in smaller-scale architectures, limiting their real-world applicability.In this paper, we propose a unified Virtual Mixture-of-Experts (MoE) fusion strategy that enhances inference performance and mitigates hallucinations in a single Qwen 1.5 0.5B model without increasing the parameter count. Our method leverages multiple domain-specific expert prompts (with the number of experts being adjustable) to guide the model from different perspectives. We apply a statistical outlier truncation strategy based on the mean and standard deviation to filter out abnormally high probability predictions, and we inject noise into the embedding space to promote output diversity. To clearly assess the contribution of each module, we adopt a fixed voting mechanism rather than a dynamic gating network, thereby avoiding additional confounding factors. We provide detailed theoretical derivations from both statistical and ensemble learning perspectives to demonstrate how our method reduces output variance and suppresses hallucinations. Extensive ablation experiments on dialogue generation tasks show that our approach significantly improves inference accuracy and robustness in small models. Additionally, we discuss methods for evaluating the orthogonality of virtual experts and outline the potential for future work involving dynamic expert weight allocation using gating networks.