Moving object segmentation plays a vital role in understanding dynamic visual environments. While existing methods rely on multi-frame image sequences to identify moving objects, single-image MOS is critical for applications like motion intention prediction and handling camera frame drops. However, segmenting moving objects from a single image remains challenging for existing methods due to the absence of temporal cues. To address this gap, we propose MovSAM, the first framework for single-image moving object segmentation. MovSAM leverages a Multimodal Large Language Model (MLLM) enhanced with Chain-of-Thought (CoT) prompting to search the moving object and generate text prompts based on deep thinking for segmentation. These prompts are cross-fused with visual features from the Segment Anything Model (SAM) and a Vision-Language Model (VLM), enabling logic-driven moving object segmentation. The segmentation results then undergo a deep thinking refinement loop, allowing MovSAM to iteratively improve its understanding of the scene context and inter-object relationships with logical reasoning. This innovative approach enables MovSAM to segment moving objects in single images by considering scene understanding. We implement MovSAM in the real world to validate its practical application and effectiveness for autonomous driving scenarios where the multi-frame methods fail. Furthermore, despite the inherent advantage of multi-frame methods in utilizing temporal information, MovSAM achieves state-of-the-art performance across public MOS benchmarks, reaching 92.5\% on J\&F. Our implementation will be available at https://github.com/IRMVLab/MovSAM.
Semi-supervised instance segmentation poses challenges due to limited labeled data, causing difficulties in accurately localizing distinct object instances. Current teacher-student frameworks still suffer from performance constraints due to unreliable pseudo-label quality stemming from limited labeled data. While the Segment Anything Model (SAM) offers robust segmentation capabilities at various granularities, directly applying SAM to this task introduces challenges such as class-agnostic predictions and potential over-segmentation. To address these complexities, we carefully integrate SAM into the semi-supervised instance segmentation framework, developing a novel distillation method that effectively captures the precise localization capabilities of SAM without compromising semantic recognition. Furthermore, we incorporate pseudo-label refinement as well as a specialized data augmentation with the refined pseudo-labels, resulting in superior performance. We establish state-of-the-art performance, and provide comprehensive experiments and ablation studies to validate the effectiveness of our proposed approach.
Motion expression video segmentation is designed to segment objects in accordance with the input motion expressions. In contrast to the conventional Referring Video Object Segmentation (RVOS), it places emphasis on motion as well as multi-object expressions, making it more arduous. Recently, Large Multimodal Models (LMMs) have begun to shine in RVOS due to their powerful vision-language perception capabilities. In this work, we propose a simple and effective inference optimization method to fully unleash the potential of LMMs in referring video segmentation. Firstly, we use Sa2VA as our baseline, which is a unified LMM for dense grounded understanding of both images and videos. Secondly, we uniformly sample the video frames during the inference process to enhance the model's understanding of the entire video. Finally, we integrate the results of multiple expert models to mitigate the erroneous predictions of a single model. Our solution achieved 61.98% J&F on the MeViS test set and ranked 1st place in the 4th PVUW Challenge MeViS Track at CVPR 2025.
Few-shot segmentation (FSS) aims to segment new classes using few annotated images. While recent FSS methods have shown considerable improvements by leveraging Segment Anything Model (SAM), they face two critical limitations: insufficient utilization of structural correlations in query images, and significant information loss when converting continuous position priors to discrete point prompts. To address these challenges, we propose CMaP-SAM, a novel framework that introduces contraction mapping theory to optimize position priors for SAM-driven few-shot segmentation. CMaP-SAM consists of three key components: (1) a contraction mapping module that formulates position prior optimization as a Banach contraction mapping with convergence guarantees. This module iteratively refines position priors through pixel-wise structural similarity, generating a converged prior that preserves both semantic guidance from reference images and structural correlations in query images; (2) an adaptive distribution alignment module bridging continuous priors with SAM's binary mask prompt encoder; and (3) a foreground-background decoupled refinement architecture producing accurate final segmentation masks. Extensive experiments demonstrate CMaP-SAM's effectiveness, achieving state-of-the-art performance with 71.1 mIoU on PASCAL-$5^i$ and 56.1 on COCO-$20^i$ datasets.
Curvilinear structure segmentation (CSS) is vital in various domains, including medical imaging, landscape analysis, industrial surface inspection, and plant analysis. While existing methods achieve high performance within specific domains, their generalizability is limited. On the other hand, large-scale models such as Segment Anything Model (SAM) exhibit strong generalization but are not optimized for curvilinear structures. Existing adaptations of SAM primarily focus on general object segmentation and lack specialized design for CSS tasks. To bridge this gap, we propose the Universal Curvilinear structure Segmentation (\textit{UCS}) model, which adapts SAM to CSS tasks while enhancing its generalization. \textit{UCS} features a novel encoder architecture integrating a pretrained SAM encoder with two innovations: a Sparse Adapter, strategically inserted to inherit the pre-trained SAM encoder's generalization capability while minimizing the number of fine-tuning parameters, and a Prompt Generation module, which leverages Fast Fourier Transform with a high-pass filter to generate curve-specific prompts. Furthermore, the \textit{UCS} incorporates a mask decoder that eliminates reliance on manual interaction through a dual-compression module: a Hierarchical Feature Compression module, which aggregates the outputs of the sampled encoder to enhance detail preservation, and a Guidance Feature Compression module, which extracts and compresses image-driven guidance features. Evaluated on a comprehensive multi-domain dataset, including an in-house dataset covering eight natural curvilinear structures, \textit{UCS} demonstrates state-of-the-art generalization and open-set segmentation performance across medical, engineering, natural, and plant imagery, establishing a new benchmark for universal CSS.
Uncertainty quantification is becoming increasingly important in image segmentation, especially for high-stakes applications like medical imaging. While conformal risk control generalizes conformal prediction beyond standard miscoverage to handle various loss functions such as false negative rate, its application to segmentation often yields inadequate conditional risk control: some images experience very high false negative rates while others have negligibly small ones. We develop Conformal Risk Adaptation (CRA), which introduces a new score function for creating adaptive prediction sets that significantly improve conditional risk control for segmentation tasks. We establish a novel theoretical framework that demonstrates a fundamental connection between conformal risk control and conformal prediction through a weighted quantile approach, applicable to any score function. To address the challenge of poorly calibrated probabilities in segmentation models, we introduce a specialized probability calibration framework that enhances the reliability of pixel-wise inclusion estimates. Using these calibrated probabilities, we propose Calibrated Conformal Risk Adaptation (CCRA) and a stratified variant (CCRA-S) that partitions images based on their characteristics and applies group-specific thresholds to further enhance conditional risk control. Our experiments on polyp segmentation demonstrate that all three methods (CRA, CCRA, and CCRA-S) provide valid marginal risk control and deliver more consistent conditional risk control across diverse images compared to standard approaches, offering a principled approach to uncertainty quantification that is particularly valuable for high-stakes and personalized segmentation applications.
3D part amodal segmentation--decomposing a 3D shape into complete, semantically meaningful parts, even when occluded--is a challenging but crucial task for 3D content creation and understanding. Existing 3D part segmentation methods only identify visible surface patches, limiting their utility. Inspired by 2D amodal segmentation, we introduce this novel task to the 3D domain and propose a practical, two-stage approach, addressing the key challenges of inferring occluded 3D geometry, maintaining global shape consistency, and handling diverse shapes with limited training data. First, we leverage existing 3D part segmentation to obtain initial, incomplete part segments. Second, we introduce HoloPart, a novel diffusion-based model, to complete these segments into full 3D parts. HoloPart utilizes a specialized architecture with local attention to capture fine-grained part geometry and global shape context attention to ensure overall shape consistency. We introduce new benchmarks based on the ABO and PartObjaverse-Tiny datasets and demonstrate that HoloPart significantly outperforms state-of-the-art shape completion methods. By incorporating HoloPart with existing segmentation techniques, we achieve promising results on 3D part amodal segmentation, opening new avenues for applications in geometry editing, animation, and material assignment.
Recent advancements in multi-modal models have significantly improved vision-language alignment in radiology. However, existing approaches struggle to effectively utilize complex radiology reports for learning, rely on low-resolution images, and offer limited interpretability in attention mechanisms. To address these challenges, we introduce RadZero, a novel similarity-based cross-attention framework for vision-language alignment in radiology with zero-shot multi-task capability. RadZero leverages large language models to extract minimal semantic sentences from radiology reports and employs a multi-positive contrastive learning strategy to effectively capture relationships between images and multiple relevant textual descriptions. It also utilizes a pre-trained vision encoder with additional trainable Transformer layers, allowing efficient high-resolution image processing. By computing similarity between text embeddings and local image patch features, RadZero enables zero-shot inference with similarity probability for classification and pixel-level cross-modal similarity maps for grounding and segmentation. Experimental results on public chest radiograph benchmarks show that RadZero outperforms state-of-the-art methods in zero-shot classification, grounding, and segmentation. Furthermore, cross-modal similarity map analysis highlights its potential for improving explainability in vision-language alignment. Additionally, qualitative evaluation demonstrates RadZero's capability for open-vocabulary semantic segmentation, further validating its effectiveness in medical imaging.
Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain knowledge, especially textual information. Conducting multimodal learning involves visual and text modalities shown as a solution, but collecting paired vision-language datasets is expensive and time-consuming, posing significant challenges. Inspired by the superior ability in numerous cross-modal tasks for Large Language Models (LLMs), we proposed a novel Vision-LLM union framework to address the issues. Specifically, we introduce frozen LLMs for zero-shot instruction generation based on corresponding medical images, imitating the radiology scanning and report generation process. {To better approximate real-world diagnostic processes}, we generate more precise text instruction from multimodal radiology images (e.g., T1-w or T2-w MRI and CT). Based on the impressive ability of semantic understanding and rich knowledge of LLMs. This process emphasizes extracting special features from different modalities and reunion the information for the ultimate clinical diagnostic. With generated text instruction, our proposed union segmentation framework can handle multimodal segmentation without prior collected vision-language datasets. To evaluate our proposed method, we conduct comprehensive experiments with influential baselines, the statistical results and the visualized case study demonstrate the superiority of our novel method.}
Accurate surgical instrument segmentation is essential in cataract surgery for tasks such as skill assessment and workflow optimization. However, limited annotated data makes it difficult to develop fully automatic models. Prompt-based methods like SAM2 offer flexibility yet remain highly sensitive to the point prompt placement, often leading to inconsistent segmentations. We address this issue by introducing RP-SAM2, which incorporates a novel shift block and a compound loss function to stabilize point prompts. Our approach reduces annotator reliance on precise point positioning while maintaining robust segmentation capabilities. Experiments on the Cataract1k dataset demonstrate that RP-SAM2 improves segmentation accuracy, with a 2% mDSC gain, a 21.36% reduction in mHD95, and decreased variance across random single-point prompt results compared to SAM2. Additionally, on the CaDIS dataset, pseudo masks generated by RP-SAM2 for fine-tuning SAM2's mask decoder outperformed those generated by SAM2. These results highlight RP-SAM2 as a practical, stable and reliable solution for semi-automatic instrument segmentation in data-constrained medical settings. The code is available at https://github.com/BioMedIA-MBZUAI/RP-SAM2.
An accurate segmentation of the pancreas on CT is crucial to identify pancreatic pathologies and extract imaging-based biomarkers. However, prior research on pancreas segmentation has primarily focused on modifying the segmentation model architecture or utilizing pre- and post-processing techniques. In this article, we investigate the utility of anatomical priors to enhance the segmentation performance of the pancreas. Two 3D full-resolution nnU-Net models were trained, one with 8 refined labels from the public PANORAMA dataset, and another that combined them with labels derived from the public TotalSegmentator (TS) tool. The addition of anatomical priors resulted in a 6\% increase in Dice score ($p < .001$) and a 36.5 mm decrease in Hausdorff distance for pancreas segmentation ($p < .001$). Moreover, the pancreas was always detected when anatomy priors were used, whereas there were 8 instances of failed detections without their use. The use of anatomy priors shows promise for pancreas segmentation and subsequent derivation of imaging biomarkers.
Chronic kidney disease (CKD) is a growing global health concern, necessitating precise and efficient image analysis to aid diagnosis and treatment planning. Automated segmentation of kidney pathology images plays a central role in facilitating clinical workflows, yet conventional segmentation models often require delicate threshold tuning. This paper proposes a novel \textit{Cascaded Threshold-Integrated U-Net (CTI-Unet)} to overcome the limitations of single-threshold segmentation. By sequentially integrating multiple thresholded outputs, our approach can reconcile noise suppression with the preservation of finer structural details. Experiments on the challenging KPIs2024 dataset demonstrate that CTI-Unet outperforms state-of-the-art architectures such as nnU-Net, Swin-Unet, and CE-Net, offering a robust and flexible framework for kidney pathology image segmentation.
Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with single-image contrast, multi-contrast, and multimodal imaging data. To improve human understanding of these black-box models, there is a growing need for Explainable AI (XAI) techniques for model transparency and accountability. Previous research has primarily focused on post hoc pixel-level explanations, using methods gradient-based and perturbation-based apporaches. These methods rely on gradients or perturbations to explain model predictions. However, these pixel-level explanations often struggle with the complexity inherent in multi-contrast magnetic resonance imaging (MRI) segmentation tasks, and the sparsely distributed explanations have limited clinical relevance. In this study, we propose using contrast-level Shapley values to explain state-of-the-art models trained on standard metrics used in brain tumor segmentation. Our results demonstrate that Shapley analysis provides valuable insights into different models' behavior used for tumor segmentation. We demonstrated a bias for U-Net towards over-weighing T1-contrast and FLAIR, while Swin-UNETR provided a cross-contrast understanding with balanced Shapley distribution.
Imbalanced datasets pose a considerable challenge in training deep learning (DL) models for medical diagnostics, particularly for segmentation tasks. Imbalance may be associated with annotation quality limited annotated datasets, rare cases, or small-scale regions of interest (ROIs). These conditions adversely affect model training and performance, leading to segmentation boundaries which deviate from the true ROIs. Traditional loss functions, such as Binary Cross Entropy, replicate annotation biases and limit model generalization. We propose a novel, statistically driven, conditionally adaptive loss function (CALF) tailored to accommodate the conditions of imbalanced datasets in DL training. It employs a data-driven methodology by estimating imbalance severity using statistical methods of skewness and kurtosis, then applies an appropriate transformation to balance the training dataset while preserving data heterogeneity. This transformative approach integrates a multifaceted process, encompassing preprocessing, dataset filtering, and dynamic loss selection to achieve optimal outcomes. We benchmark our method against conventional loss functions using qualitative and quantitative evaluations. Experiments using large-scale open-source datasets (i.e., UPENN-GBM, UCSF, LGG, and BraTS) validate our approach, demonstrating substantial segmentation improvements. Code availability: https://anonymous.4open.science/r/MICCAI-Submission-43F9/.
Convolutional neural networks like U-Net excel in medical image segmentation, while attention mechanisms and KAN enhance feature extraction. Meta's SAM 2 uses Vision Transformers for prompt-based segmentation without fine-tuning. However, biases in these models impact generalization with limited data. In this study, we systematically evaluate and compare the performance of three CNN-based models, i.e., U-Net, Attention U-Net, and U-KAN, and one transformer-based model, i.e., SAM 2 for segmenting femur bone structures in MRI scan. The dataset comprises 11,164 MRI scans with detailed annotations of femoral regions. Performance is assessed using the Dice Similarity Coefficient, which ranges from 0.932 to 0.954. Attention U-Net achieves the highest overall scores, while U-KAN demonstrated superior performance in anatomical regions with a smaller region of interest, leveraging its enhanced learning capacity to improve segmentation accuracy.
High-resolution segmentation is critical for precise disease diagnosis by extracting micro-imaging information from medical images. Existing transformer-based encoder-decoder frameworks have demonstrated remarkable versatility and zero-shot performance in medical segmentation. While beneficial, they usually require huge memory costs when handling large-size segmentation mask predictions, which are expensive to apply to real-world scenarios. To address this limitation, we propose a memory-efficient framework for high-resolution medical image segmentation, called HRMedSeg. Specifically, we first devise a lightweight gated vision transformer (LGViT) as our image encoder to model long-range dependencies with linear complexity. Then, we design an efficient cross-multiscale decoder (ECM-Decoder) to generate high-resolution segmentation masks. Moreover, we utilize feature distillation during pretraining to unleash the potential of our proposed model. Extensive experiments reveal that HRMedSeg outperforms state-of-the-arts in diverse high-resolution medical image segmentation tasks. In particular, HRMedSeg uses only 0.59GB GPU memory per batch during fine-tuning, demonstrating low training costs. Besides, when HRMedSeg meets the Segment Anything Model (SAM), our HRMedSegSAM takes 0.61% parameters of SAM-H. The code is available at https://github.com/xq141839/HRMedSeg.
Segment Anything 2 (SAM2) enables robust single-object tracking using segmentation. To extend this to multi-object tracking (MOT), we propose SAM2MOT, introducing a novel Tracking by Segmentation paradigm. Unlike Tracking by Detection or Tracking by Query, SAM2MOT directly generates tracking boxes from segmentation masks, reducing reliance on detection accuracy. SAM2MOT has two key advantages: zero-shot generalization, allowing it to work across datasets without fine-tuning, and strong object association, inherited from SAM2. To further improve performance, we integrate a trajectory manager system for precise object addition and removal, and a cross-object interaction module to handle occlusions. Experiments on DanceTrack, UAVDT, and BDD100K show state-of-the-art results. Notably, SAM2MOT outperforms existing methods on DanceTrack by +2.1 HOTA and +4.5 IDF1, highlighting its effectiveness in MOT. Code is available at https://github.com/TripleJoy/SAM2MOT.
Registering human meshes to 3D point clouds is essential for applications such as augmented reality and human-robot interaction but often yields imprecise results due to noise and background clutter in real-world data. We introduce a hybrid approach that incorporates body-part segmentation into the mesh fitting process, enhancing both human pose estimation and segmentation accuracy. Our method first assigns body part labels to individual points, which then guide a two-step SMPL-X fitting: initial pose and orientation estimation using body part centroids, followed by global refinement of the point cloud alignment. Additionally, we demonstrate that the fitted human mesh can refine body part labels, leading to improved segmentation. Evaluations on the cluttered and noisy real-world datasets InterCap, EgoBody, and BEHAVE show that our approach significantly outperforms prior methods in both pose estimation and segmentation accuracy. Code and results are available on our project website: https://segfit.github.io
Cropland non-agriculturalization refers to the conversion of arable land into non-agricultural uses such as forests, residential areas, and construction sites. This phenomenon not only directly leads to the loss of cropland resources but also poses systemic threats to food security and agricultural sustainability. Accurate identification of cropland and non-cropland areas is crucial for detecting and addressing this issue. Traditional CNNs employ static convolution layers, while dynamic convolution studies demonstrate that adaptively weighting multiple convolutional kernels through attention mechanisms can enhance accuracy. However, existing dynamic convolution methods relying on Global Average Pooling (GAP) for attention weight allocation suffer from information loss, limiting segmentation precision. This paper proposes Frequency-Aware Dynamic Convolution (FADConv) and a Frequency Attention (FAT) module to address these limitations. Building upon the foundational structure of dynamic convolution, we designed FADConv by integrating 2D Discrete Cosine Transform (2D DCT) to capture frequency domain features and fuse them. FAT module generates high-quality attention weights that replace the traditional GAP method,making the combination between dynamic convolution kernels more reasonable.Experiments on the GID and Hi-CNA datasets demonstrate that FADConv significantly improves segmentation accuracy with minimal computational overhead. For instance, ResNet18 with FADConv achieves 1.9% and 2.7% increases in F1-score and IoU for cropland segmentation on GID, with only 58.87M additional MAdds. Compared to other dynamic convolution approaches, FADConv exhibits superior performance in cropland segmentation tasks.
Accurate lumbar spine segmentation is crucial for diagnosing spinal disorders. Existing methods typically use coarse-grained segmentation strategies that lack the fine detail needed for precise diagnosis. Additionally, their reliance on visual-only models hinders the capture of anatomical semantics, leading to misclassified categories and poor segmentation details. To address these limitations, we present ATM-Net, an innovative framework that employs an anatomy-aware, text-guided, multi-modal fusion mechanism for fine-grained segmentation of lumbar substructures, i.e., vertebrae (VBs), intervertebral discs (IDs), and spinal canal (SC). ATM-Net adopts the Anatomy-aware Text Prompt Generator (ATPG) to adaptively convert image annotations into anatomy-aware prompts in different views. These insights are further integrated with image features via the Holistic Anatomy-aware Semantic Fusion (HASF) module, building a comprehensive anatomical context. The Channel-wise Contrastive Anatomy-Aware Enhancement (CCAE) module further enhances class discrimination and refines segmentation through class-wise channel-level multi-modal contrastive learning. Extensive experiments on the MRSpineSeg and SPIDER datasets demonstrate that ATM-Net significantly outperforms state-of-the-art methods, with consistent improvements regarding class discrimination and segmentation details. For example, ATM-Net achieves Dice of 79.39% and HD95 of 9.91 pixels on SPIDER, outperforming the competitive SpineParseNet by 8.31% and 4.14 pixels, respectively.