We propose a novel retinal vessel segmentation network, the Weighted Multi-Kernel Attention Network (WMKA-Net), which aims to address the issues of insufficient multiscale feature capture, loss of contextual information, and noise sensitivity in retinal vessel segmentation. WMKA-Net significantly improves the segmentation performance of small vessels and low-contrast regions by integrating several innovative components, including the MultiKernelFeature Fusion Module (MKDC), the Progressive Feature Weighting Fusion Strategy (UDFF), and the Attention Mechanism Module (AttentionBlock). The MKDC module employs multiscale parallel convolutional kernels to extract vessel characteristics, thereby enhancing the ability to capture complex vascular structures. The UDFF strategy optimizes the transmission of feature information by weighted fusion of high- and low-level features. The AttentionBlock highlights key regions and suppresses noise interference through the attention mechanism. Experimental results demonstrate that WMKA-Net achieves excellent segmentation performance in multiple public datasets, particularly in segmentation of small vessels and processing of pathological regions. This work provides a robust and efficient new method for segmentation of the retinal vessel.
Accurate and efficient medical image segmentation is crucial for advancing clinical diagnostics and surgical planning, yet remains a complex challenge due to the variability in anatomical structures and the demand for low-complexity models. In this paper, we introduced Med-2D SegNet, a novel and highly efficient segmentation architecture that delivers outstanding accuracy while maintaining a minimal computational footprint. Med-2D SegNet achieves state-of-the-art performance across multiple benchmark datasets, including KVASIR-SEG, PH2, EndoVis, and GLAS, with an average Dice similarity coefficient (DSC) of 89.77% across 20 diverse datasets. Central to its success is the compact Med Block, a specialized encoder design that incorporates dimension expansion and parameter reduction, enabling precise feature extraction while keeping model parameters to a low count of just 2.07 million. Med-2D SegNet excels in cross-dataset generalization, particularly in polyp segmentation, where it was trained on KVASIR-SEG and showed strong performance on unseen datasets, demonstrating its robustness in zero-shot learning scenarios, even though we acknowledge that further improvements are possible. With top-tier performance in both binary and multi-class segmentation, Med-2D SegNet redefines the balance between accuracy and efficiency, setting a new benchmark for medical image analysis. This work paves the way for developing accessible, high-performance diagnostic tools suitable for clinical environments and resource-constrained settings, making it a step forward in the democratization of advanced medical technology.
This paper focuses on a key challenge in visual art understanding: given an art image, the model pinpoints pixel regions that trigger a specific human emotion, and generates linguistic explanations for the emotional arousal. Despite recent advances in art understanding, pixel-level emotion understanding still faces a dual challenge: first, the subjectivity of emotion makes it difficult for general segmentation models like SAM to adapt to emotion-oriented segmentation tasks; and second, the abstract nature of art expression makes it difficult for captioning models to balance pixel-level semantic understanding and emotion reasoning. To solve the above problems, this paper proposes the Emotion stimuli Segmentation and Explanation Model (EmoSEM) to endow the segmentation model SAM with emotion comprehension capability. First, to enable the model to perform segmentation under the guidance of emotional intent well, we introduce an emotional prompt with a learnable mask token as the conditional input for segmentation decoding. Then, we design an emotion projector to establish the association between emotion and visual features. Next, more importantly, to address emotion-visual stimuli alignment, we develop a lightweight prefix projector, a module that fuses the learned emotional mask with the corresponding emotion into a unified representation compatible with the language model.Finally, we input the joint visual, mask, and emotional tokens into the language model and output the emotional explanations. It ensures that the generated interpretations remain semantically and emotionally coherent with the visual stimuli. The method innovatively realizes end-to-end modeling from low-level pixel features to high-level emotion interpretation, providing the first interpretable fine-grained analysis framework for artistic emotion computing. Extensive experiments validate the effectiveness of our model.
Standard semantic instance segmentation provides useful, but inherently 2D information from a single image. To enable 3D analysis, one usually integrates absolute monocular depth estimation with instance segmentation. However, monocular depth is a difficult task. Instead, we leverage a simpler single-image task, occlusion-based relative depth ordering, providing coarser but useful 3D information. We show that relative depth ordering works more reliably from occlusions than from absolute depth. We propose to solve the joint task of relative depth ordering and segmentation of instances based on occlusions. We call this task Occlusion-Ordered Semantic Instance Segmentation (OOSIS). We develop an approach to OOSIS that extracts instances and their occlusion order simultaneously from oriented occlusion boundaries and semantic segmentation. Unlike popular detect-and-segment framework for instance segmentation, combining occlusion ordering with instance segmentation allows a simple and clean formulation of OOSIS as a labeling problem. As a part of our solution for OOSIS, we develop a novel oriented occlusion boundaries approach that significantly outperforms prior work. We also develop a new joint OOSIS metric based both on instance mask accuracy and correctness of their occlusion order. We achieve better performance than strong baselines on KINS and COCOA datasets.
Cancer remains one of the leading causes of mortality worldwide, and among its many forms, brain tumors are particularly notorious due to their aggressive nature and the critical challenges involved in early diagnosis. Recent advances in artificial intelligence have shown great promise in assisting medical professionals with precise tumor segmentation, a key step in timely diagnosis and treatment planning. However, many state-of-the-art segmentation methods require extensive computational resources and prolonged training times, limiting their practical application in resource-constrained settings. In this work, we present a novel dual-decoder U-Net architecture enhanced with attention-gated skip connections, designed specifically for brain tumor segmentation from MRI scans. Our approach balances efficiency and accuracy by achieving competitive segmentation performance while significantly reducing training demands. Evaluated on the BraTS 2020 dataset, the proposed model achieved Dice scores of 85.06% for Whole Tumor (WT), 80.61% for Tumor Core (TC), and 71.26% for Enhancing Tumor (ET) in only 50 epochs, surpassing several commonly used U-Net variants. Our model demonstrates that high-quality brain tumor segmentation is attainable even under limited computational resources, thereby offering a viable solution for researchers and clinicians operating with modest hardware. This resource-efficient model has the potential to improve early detection and diagnosis of brain tumors, ultimately contributing to better patient outcomes
Pelvic fractures, often caused by high-impact trauma, frequently require surgical intervention. Imaging techniques such as CT and 2D X-ray imaging are used to transfer the surgical plan to the operating room through image registration, enabling quick intraoperative adjustments. Specifically, segmenting pelvic fractures from 2D X-ray imaging can assist in accurately positioning bone fragments and guiding the placement of screws or metal plates. In this study, we propose a novel deep learning-based category and fragment segmentation (CFS) framework for the automatic segmentation of pelvic bone fragments in 2D X-ray images. The framework consists of three consecutive steps: category segmentation, fragment segmentation, and post-processing. Our best model achieves an IoU of 0.91 for anatomical structures and 0.78 for fracture segmentation. Results demonstrate that the CFS framework is effective and accurate.
Root canal (RC) treatment is a highly delicate and technically complex procedure in clinical practice, heavily influenced by the clinicians' experience and subjective judgment. Deep learning has made significant advancements in the field of computer-aided diagnosis (CAD) because it can provide more objective and accurate diagnostic results. However, its application in RC treatment is still relatively rare, mainly due to the lack of public datasets in this field. To address this issue, in this paper, we established a First Molar Root Canal segmentation dataset called FMRC-2025. Additionally, to alleviate the workload of manual annotation for dentists and fully leverage the unlabeled data, we designed a Cross-Frequency Collaborative training semi-supervised learning (SSL) Network called CFC-Net. It consists of two components: (1) Cross-Frequency Collaborative Mean Teacher (CFC-MT), which introduces two specialized students (SS) and one comprehensive teacher (CT) for collaborative multi-frequency training. The CT and SS are trained on different frequency components while fully integrating multi-frequency knowledge through cross and full frequency consistency supervisions. (2) Uncertainty-guided Cross-Frequency Mix (UCF-Mix) mechanism enables the network to generate high-confidence pseudo-labels while learning to integrate multi-frequency information and maintaining the structural integrity of the targets. Extensive experiments on FMRC-2025 and three public dental datasets demonstrate that CFC-MT is effective for RC segmentation and can also exhibit strong generalizability on other dental segmentation tasks, outperforming state-of-the-art SSL medical image segmentation methods. Codes and dataset will be released.
Referring video object segmentation (RVOS) aims to segment objects in videos guided by natural language descriptions. We propose FS-RVOS, a Transformer-based model with two key components: a cross-modal affinity module and an instance sequence matching strategy, which extends FS-RVOS to multi-object segmentation (FS-RVMOS). Experiments show FS-RVOS and FS-RVMOS outperform state-of-the-art methods across diverse benchmarks, demonstrating superior robustness and accuracy.
Accurate vascular segmentation is essential for coronary visualization and the diagnosis of coronary heart disease. This task involves the extraction of sparse tree-like vascular branches from the volumetric space. However, existing methods have faced significant challenges due to discontinuous vascular segmentation and missing endpoints. To address this issue, a 3D vision graph neural network framework, named ViG3D-UNet, was introduced. This method integrates 3D graph representation and aggregation within a U-shaped architecture to facilitate continuous vascular segmentation. The ViG3D module captures volumetric vascular connectivity and topology, while the convolutional module extracts fine vascular details. These two branches are combined through channel attention to form the encoder feature. Subsequently, a paperclip-shaped offset decoder minimizes redundant computations in the sparse feature space and restores the feature map size to match the original input dimensions. To evaluate the effectiveness of the proposed approach for continuous vascular segmentation, evaluations were performed on two public datasets, ASOCA and ImageCAS. The segmentation results show that the ViG3D-UNet surpassed competing methods in maintaining vascular segmentation connectivity while achieving high segmentation accuracy. Our code will be available soon.
Accurate retinal vessel segmentation provides essential structural information for ophthalmic image analysis. However, existing methods struggle with challenges such as multi-scale vessel variability, complex curvatures, and ambiguous boundaries. While Convolutional Neural Networks (CNNs), Transformer-based models and Mamba-based architectures have advanced the field, they often suffer from vascular discontinuities or edge feature ambiguity. To address these limitations, we propose a novel hybrid framework that synergistically integrates CNNs and Mamba for high-precision retinal vessel segmentation. Our approach introduces three key innovations: 1) The proposed High-Resolution Edge Fuse Network is a high-resolution preserving hybrid segmentation framework that combines a multi-scale backbone with the Multi-scale Retina Edge Fusion (MREF) module to enhance edge features, ensuring accurate and robust vessel segmentation. 2) The Dynamic Snake Visual State Space block combines Dynamic Snake Convolution with Mamba to adaptively capture vessel curvature details and long-range dependencies. An improved eight-directional 2D Snake-Selective Scan mechanism and a dynamic weighting strategy enhance the perception of complex vascular topologies. 3) The MREF module enhances boundary precision through multi-scale edge feature aggregation, suppressing noise while emphasizing critical vessel structures across scales. Experiments on three public datasets demonstrate that our method achieves state-of-the-art performance, particularly in maintaining vascular continuity and effectively segmenting vessels in low-contrast regions. This work provides a robust method for clinical applications requiring accurate retinal vessel analysis. The code is available at https://github.com/frank-oy/HREFNet.
Semantic segmentation of SAR images has garnered significant attention in remote sensing due to the immunity of SAR sensors to cloudy weather and light conditions. Nevertheless, SAR imagery lacks detailed information and is plagued by significant speckle noise, rendering the annotation or segmentation of SAR images a formidable task. Recent efforts have resorted to annotating paired optical-SAR images to generate pseudo-labels through the utilization of an optical image segmentation network. However, these pseudo-labels are laden with noise, leading to suboptimal performance in SAR image segmentation. In this study, we introduce a more precise method for generating pseudo-labels by incorporating semi-supervised learning alongside a novel image resolution alignment augmentation. Furthermore, we introduce a symmetric cross-entropy loss to mitigate the impact of noisy pseudo-labels. Additionally, a bag of training and testing tricks is utilized to generate better land-cover mapping results. Our experiments on the GRSS data fusion contest indicate the effectiveness of the proposed method, which achieves first place. The code is available at https://github.com/StuLiu/DFC2025Track1.git.
Colonoscopy is vital in the early diagnosis of colorectal polyps. Regular screenings can effectively prevent benign polyps from progressing to CRC. While deep learning has made impressive strides in polyp segmentation, most existing models are trained on single-modality and single-center data, making them less effective in real-world clinical environments. To overcome these limitations, we propose FocusNet, a Transformer-enhanced focus attention network designed to improve polyp segmentation. FocusNet incorporates three essential modules: the Cross-semantic Interaction Decoder Module (CIDM) for generating coarse segmentation maps, the Detail Enhancement Module (DEM) for refining shallow features, and the Focus Attention Module (FAM), to balance local detail and global context through local and pooling attention mechanisms. We evaluate our model on PolypDB, a newly introduced dataset with multi-modality and multi-center data for building more reliable segmentation methods. Extensive experiments showed that FocusNet consistently outperforms existing state-of-the-art approaches with a high dice coefficients of 82.47% on the BLI modality, 88.46% on FICE, 92.04% on LCI, 82.09% on the NBI and 93.42% on WLI modality, demonstrating its accuracy and robustness across five different modalities. The source code for FocusNet is available at https://github.com/JunZengz/FocusNet.
Anomaly segmentation is essential for industrial quality, maintenance, and stability. Existing text-guided zero-shot anomaly segmentation models are effective but rely on fixed prompts, limiting adaptability in diverse industrial scenarios. This highlights the need for flexible, context-aware prompting strategies. We propose Image-Aware Prompt Anomaly Segmentation (IAP-AS), which enhances anomaly segmentation by generating dynamic, context-aware prompts using an image tagging model and a large language model (LLM). IAP-AS extracts object attributes from images to generate context-aware prompts, improving adaptability and generalization in dynamic and unstructured industrial environments. In our experiments, IAP-AS improves the F1-max metric by up to 10%, demonstrating superior adaptability and generalization. It provides a scalable solution for anomaly segmentation across industries
Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images. Precise delineation of cardiac substructures and extraction of their morphological attributes are essential for evaluating the cardiac function, and diagnosing cardiovascular disease such as cardiomyopathy, valvular diseases, abnormalities related to septum perforations, and blood-flow rate. Semantic segmentation labels the CMR image at the pixel level, and localizes its subcomponents to facilitate the detection of abnormalities, including abnormalities in cardiac wall motion in an aging heart with muscle abnormalities, vascular abnormalities, and valvular abnormalities. In this paper, we describe a model to improve semantic segmentation of CMR images. The model extracts edge-attributes and context information during down-sampling of the U-Net and infuses this information during up-sampling to localize three major cardiac structures: left ventricle cavity (LV); right ventricle cavity (RV); and LV myocardium (LMyo). We present an algorithm and performance results. A comparison of our model with previous leading models, using similarity metrics between actual image and segmented image, shows that our approach improves Dice similarity coefficient (DSC) by 2%-11% and lowers Hausdorff distance (HD) by 1.6 to 5.7 mm.
Reliable tumor segmentation in thoracic computed tomography (CT) remains challenging due to boundary ambiguity, class imbalance, and anatomical variability. We propose an uncertainty-guided, coarse-to-fine segmentation framework that combines full-volume tumor localization with refined region-of-interest (ROI) segmentation, enhanced by anatomically aware post-processing. The first-stage model generates a coarse prediction, followed by anatomically informed filtering based on lung overlap, proximity to lung surfaces, and component size. The resulting ROIs are segmented by a second-stage model trained with uncertainty-aware loss functions to improve accuracy and boundary calibration in ambiguous regions. Experiments on private and public datasets demonstrate improvements in Dice and Hausdorff scores, with fewer false positives and enhanced spatial interpretability. These results highlight the value of combining uncertainty modeling and anatomical priors in cascaded segmentation pipelines for robust and clinically meaningful tumor delineation. On the Orlando dataset, our framework improved Swin UNETR Dice from 0.4690 to 0.6447. Reduction in spurious components was strongly correlated with segmentation gains, underscoring the value of anatomically informed post-processing.
Menisci are cartilaginous tissue found within the knee that contribute to joint lubrication and weight dispersal. Damage to menisci can lead to onset and progression of knee osteoarthritis (OA), a condition that is a leading cause of disability, and for which there are few effective therapies. Accurate automated segmentation of menisci would allow for earlier detection and treatment of meniscal abnormalities, as well as shedding more light on the role the menisci play in OA pathogenesis. Focus in this area has mainly used variants of convolutional networks, but there has been no attempt to utilise recent large vision transformer segmentation models. The Segment Anything Model (SAM) is a so-called foundation segmentation model, which has been found useful across a range of different tasks due to the large volume of data used for training the model. In this study, SAM was adapted to perform fully-automated segmentation of menisci from 3D knee magnetic resonance images. A 3D U-Net was also trained as a baseline. It was found that, when fine-tuning only the decoder, SAM was unable to compete with 3D U-Net, achieving a Dice score of $0.81\pm0.03$, compared to $0.87\pm0.03$, on a held-out test set. When fine-tuning SAM end-to-end, a Dice score of $0.87\pm0.03$ was achieved. The performance of both the end-to-end trained SAM configuration and the 3D U-Net were comparable to the winning Dice score ($0.88\pm0.03$) in the IWOAI Knee MRI Segmentation Challenge 2019. Performance in terms of the Hausdorff Distance showed that both configurations of SAM were inferior to 3D U-Net in matching the meniscus morphology. Results demonstrated that, despite its generalisability, SAM was unable to outperform a basic 3D U-Net in meniscus segmentation, and may not be suitable for similar 3D medical image segmentation tasks also involving fine anatomical structures with low contrast and poorly-defined boundaries.
The elliptical shape prior information plays a vital role in improving the accuracy of image segmentation for specific tasks in medical and natural images. Existing deep learning-based segmentation methods, including the Segment Anything Model (SAM), often struggle to produce segmentation results with elliptical shapes efficiently. This paper proposes a new approach to integrate the prior of elliptical shapes into the deep learning-based SAM image segmentation techniques using variational methods. The proposed method establishes a parameterized elliptical contour field, which constrains the segmentation results to align with predefined elliptical contours. Utilizing the dual algorithm, the model seamlessly integrates image features with elliptical priors and spatial regularization priors, thereby greatly enhancing segmentation accuracy. By decomposing SAM into four mathematical sub-problems, we integrate the variational ellipse prior to design a new SAM network structure, ensuring that the segmentation output of SAM consists of elliptical regions. Experimental results on some specific image datasets demonstrate an improvement over the original SAM.
Given a single labeled example, in-context segmentation aims to segment corresponding objects. This setting, known as one-shot segmentation in few-shot learning, explores the segmentation model's generalization ability and has been applied to various vision tasks, including scene understanding and image/video editing. While recent Segment Anything Models have achieved state-of-the-art results in interactive segmentation, these approaches are not directly applicable to in-context segmentation. In this work, we propose the Dual Consistency SAM (DC-SAM) method based on prompt-tuning to adapt SAM and SAM2 for in-context segmentation of both images and videos. Our key insights are to enhance the features of the SAM's prompt encoder in segmentation by providing high-quality visual prompts. When generating a mask prior, we fuse the SAM features to better align the prompt encoder. Then, we design a cycle-consistent cross-attention on fused features and initial visual prompts. Next, a dual-branch design is provided by using the discriminative positive and negative prompts in the prompt encoder. Furthermore, we design a simple mask-tube training strategy to adopt our proposed dual consistency method into the mask tube. Although the proposed DC-SAM is primarily designed for images, it can be seamlessly extended to the video domain with the support of SAM2. Given the absence of in-context segmentation in the video domain, we manually curate and construct the first benchmark from existing video segmentation datasets, named In-Context Video Object Segmentation (IC-VOS), to better assess the in-context capability of the model. Extensive experiments demonstrate that our method achieves 55.5 (+1.4) mIoU on COCO-20i, 73.0 (+1.1) mIoU on PASCAL-5i, and a J&F score of 71.52 on the proposed IC-VOS benchmark. Our source code and benchmark are available at https://github.com/zaplm/DC-SAM.
Pap smear image segmentation is crucial for cervical cancer diagnosis. However, traditional segmentation models often struggle with complex cellular structures and variations in pap smear images. This study proposes a hybrid Dense-UNet201 optimization approach that integrates a pretrained DenseNet201 as the encoder for the U-Net architecture and optimizes it using the spider monkey optimization (SMO) algorithm. The Dense-UNet201 model excelled at feature extraction. The SMO was modified to handle categorical and discrete parameters. The SIPaKMeD dataset was used in this study and evaluated using key performance metrics, including loss, accuracy, Intersection over Union (IoU), and Dice coefficient. The experimental results showed that Dense-UNet201 outperformed U-Net, Res-UNet50, and Efficient-UNetB0. SMO Dense-UNet201 achieved a segmentation accuracy of 96.16%, an IoU of 91.63%, and a Dice coefficient score of 95.63%. These findings underscore the effectiveness of image preprocessing, pretrained models, and metaheuristic optimization in improving medical image analysis and provide new insights into cervical cell segmentation methods.
Transvaginal ultrasound is a critical imaging modality for evaluating cervical anatomy and detecting physiological changes. However, accurate segmentation of cervical structures remains challenging due to low contrast, shadow artifacts, and indistinct boundaries. While convolutional neural networks (CNNs) have demonstrated efficacy in medical image segmentation, their reliance on large-scale annotated datasets presents a significant limitation in clinical ultrasound imaging. Semi-supervised learning (SSL) offers a potential solution by utilizing unlabeled data, yet existing teacher-student frameworks often encounter confirmation bias and high computational costs. In this paper, a novel semi-supervised segmentation framework, called HDC, is proposed incorporating adaptive consistency learning with a single-teacher architecture. The framework introduces a hierarchical distillation mechanism with two objectives: Correlation Guidance Loss for aligning feature representations and Mutual Information Loss for stabilizing noisy student learning. The proposed approach reduces model complexity while enhancing generalization. Experiments on fetal ultrasound datasets, FUGC and PSFH, demonstrate competitive performance with reduced computational overhead compared to multi-teacher models.