Point-cloud semantic segmentation underpins a wide range of critical applications. Although recent deep architectures and large-scale datasets have driven impressive closed-set performance, these models struggle to recognize or properly segment objects outside their training classes. This gap has sparked interest in Open-Set Semantic Segmentation (O3S), where models must both correctly label known categories and detect novel, unseen classes. In this paper, we propose a plug and play framework for O3S. By modeling the segmentation pipeline as a conditional Markov chain, we derive a novel regularizer term dubbed Conditional Channel Capacity Maximization (3CM), that maximizes the mutual information between features and predictions conditioned on each class. When incorporated into standard loss functions, 3CM encourages the encoder to retain richer, label-dependent features, thereby enhancing the network's ability to distinguish and segment previously unseen categories. Experimental results demonstrate effectiveness of proposed method on detecting unseen objects. We further outline future directions for dynamic open-world adaptation and efficient information-theoretic estimation.
Accurate road segmentation is essential for autonomous driving and ADAS, enabling effective navigation in complex environments. This study examines how model architecture and dataset choice affect segmentation by training a modified VGG-16 on the Comma10k dataset and a modified U-Net on the KITTI Road dataset. Both models achieved high accuracy, with cross-dataset testing showing VGG-16 outperforming U-Net despite U-Net being trained for more epochs. We analyze model performance using metrics such as F1-score, mean intersection over union, and precision, discussing how architecture and dataset impact results.
The efficient rendering and explicit nature of 3DGS promote the advancement of 3D scene manipulation. However, existing methods typically encounter challenges in controlling the manipulation region and are unable to furnish the user with interactive feedback, which inevitably leads to unexpected results. Intuitively, incorporating interactive 3D segmentation tools can compensate for this deficiency. Nevertheless, existing segmentation frameworks impose a pre-processing step of scene-specific parameter training, which limits the efficiency and flexibility of scene manipulation. To deliver a 3D region control module that is well-suited for scene manipulation with reliable efficiency, we propose interactive Segment-and-Manipulate 3D Gaussians (iSegMan), an interactive segmentation and manipulation framework that only requires simple 2D user interactions in any view. To propagate user interactions to other views, we propose Epipolar-guided Interaction Propagation (EIP), which innovatively exploits epipolar constraint for efficient and robust interaction matching. To avoid scene-specific training to maintain efficiency, we further propose the novel Visibility-based Gaussian Voting (VGV), which obtains 2D segmentations from SAM and models the region extraction as a voting game between 2D Pixels and 3D Gaussians based on Gaussian visibility. Taking advantage of the efficient and precise region control of EIP and VGV, we put forth a Manipulation Toolbox to implement various functions on selected regions, enhancing the controllability, flexibility and practicality of scene manipulation. Extensive results on 3D scene manipulation and segmentation tasks fully demonstrate the significant advantages of iSegMan. Project page is available at https://zhao-yian.github.io/iSegMan.
Accurate segmentation of brain images typically requires the integration of complementary information from multiple image modalities. However, clinical data for all modalities may not be available for every patient, creating a significant challenge. To address this, previous studies encode multiple modalities into a shared latent space. While somewhat effective, it remains suboptimal, as each modality contains distinct and valuable information. In this study, we propose DC-Seg (Disentangled Contrastive Learning for Segmentation), a new method that explicitly disentangles images into modality-invariant anatomical representation and modality-specific representation, by using anatomical contrastive learning and modality contrastive learning respectively. This solution improves the separation of anatomical and modality-specific features by considering the modality gaps, leading to more robust representations. Furthermore, we introduce a segmentation-based regularizer that enhances the model's robustness to missing modalities. Extensive experiments on the BraTS 2020 and a private white matter hyperintensity(WMH) segmentation dataset demonstrate that DC-Seg outperforms state-of-the-art methods in handling incomplete multimodal brain tumor segmentation tasks with varying missing modalities, while also demonstrate strong generalizability in WMH segmentation. The code is available at https://github.com/CuCl-2/DC-Seg.
This paper addresses the task of cross-modal medical image segmentation by exploring unsupervised domain adaptation (UDA) approaches. We propose a model-agnostic UDA framework, LowBridge, which builds on a simple observation that cross-modal images share some similar low-level features (e.g., edges) as they are depicting the same structures. Specifically, we first train a generative model to recover the source images from their edge features, followed by training a segmentation model on the generated source images, separately. At test time, edge features from the target images are input to the pretrained generative model to generate source-style target domain images, which are then segmented using the pretrained segmentation network. Despite its simplicity, extensive experiments on various publicly available datasets demonstrate that \proposed achieves state-of-the-art performance, outperforming eleven existing UDA approaches under different settings. Notably, further ablation studies show that \proposed is agnostic to different types of generative and segmentation models, suggesting its potential to be seamlessly plugged with the most advanced models to achieve even more outstanding results in the future. The code is available at https://github.com/JoshuaLPF/LowBridge.
Recent advancements in prompt-based medical image segmentation have enabled clinicians to identify tumors using simple input like bounding boxes or text prompts. However, existing methods face challenges when doctors need to interact through natural language or when position reasoning is required - understanding spatial relationships between anatomical structures and pathologies. We present PRS-Med, a framework that integrates vision-language models with segmentation capabilities to generate both accurate segmentation masks and corresponding spatial reasoning outputs. Additionally, we introduce the MMRS dataset (Multimodal Medical in Positional Reasoning Segmentation), which provides diverse, spatially-grounded question-answer pairs to address the lack of position reasoning data in medical imaging. PRS-Med demonstrates superior performance across six imaging modalities (CT, MRI, X-ray, ultrasound, endoscopy, RGB), significantly outperforming state-of-the-art methods in both segmentation accuracy and position reasoning. Our approach enables intuitive doctor-system interaction through natural language, facilitating more efficient diagnoses. Our dataset pipeline, model, and codebase will be released to foster further research in spatially-aware multimodal reasoning for medical applications.
Medical image segmentation relies heavily on convolutional neural networks (CNNs) and Transformer-based models. However, CNNs are constrained by limited receptive fields, while Transformers suffer from scalability challenges due to their quadratic computational complexity. To address these limitations, recent advances have explored alternative architectures. The state-space model Mamba offers near-linear complexity while capturing long-range dependencies, and the Kolmogorov-Arnold Network (KAN) enhances nonlinear expressiveness by replacing fixed activation functions with learnable ones. Building on these strengths, we propose MedVKAN, an efficient feature extraction model integrating Mamba and KAN. Specifically, we introduce the EFC-KAN module, which enhances KAN with convolutional operations to improve local pixel interaction. We further design the VKAN module, integrating Mamba with EFC-KAN as a replacement for Transformer modules, significantly improving feature extraction. Extensive experiments on five public medical image segmentation datasets show that MedVKAN achieves state-of-the-art performance on four datasets and ranks second on the remaining one. These results validate the potential of Mamba and KAN for medical image segmentation while introducing an innovative and computationally efficient feature extraction framework. The code is available at: https://github.com/beginner-cjh/MedVKAN.
We report on the application of a high-capacity semantic segmentation pipeline to the GOOSE 2D Semantic Segmentation Challenge for unstructured off-road environments. Using a FlashInternImage-B backbone together with a UPerNet decoder, we adapt established techniques, rather than designing new ones, to the distinctive conditions of off-road scenes. Our training recipe couples strong photometric distortion augmentation (to emulate the wide lighting variations of outdoor terrain) with an Exponential Moving Average (EMA) of weights for better generalization. Using only the GOOSE training dataset, we achieve 88.8\% mIoU on the validation set.
We propose FlowCut, a simple and capable method for unsupervised video instance segmentation consisting of a three-stage framework to construct a high-quality video dataset with pseudo labels. To our knowledge, our work is the first attempt to curate a video dataset with pseudo-labels for unsupervised video instance segmentation. In the first stage, we generate pseudo-instance masks by exploiting the affinities of features from both images and optical flows. In the second stage, we construct short video segments containing high-quality, consistent pseudo-instance masks by temporally matching them across the frames. In the third stage, we use the YouTubeVIS-2021 video dataset to extract our training instance segmentation set, and then train a video segmentation model. FlowCut achieves state-of-the-art performance on the YouTubeVIS-2019, YouTubeVIS-2021, DAVIS-2017, and DAVIS-2017 Motion benchmarks.
Pre-training on real-image datasets has been widely proven effective for improving instance segmentation. However, industrial applications face two key challenges: (1) legal and ethical restrictions, such as ImageNet's prohibition of commercial use, and (2) limited transferability due to the domain gap between web images and industrial imagery. Even recent vision foundation models, including the segment anything model (SAM), show notable performance degradation in industrial settings. These challenges raise critical questions: Can we build a vision foundation model for industrial applications without relying on real images or manual annotations? And can such models outperform even fine-tuned SAM on industrial datasets? To address these questions, we propose the Instance Core Segmentation Dataset (InsCore), a synthetic pre-training dataset based on formula-driven supervised learning (FDSL). InsCore generates fully annotated instance segmentation images that reflect key characteristics of industrial data, including complex occlusions, dense hierarchical masks, and diverse non-rigid shapes, distinct from typical web imagery. Unlike previous methods, InsCore requires neither real images nor human annotations. Experiments on five industrial datasets show that models pre-trained with InsCore outperform those trained on COCO and ImageNet-21k, as well as fine-tuned SAM, achieving an average improvement of 6.2 points in instance segmentation performance. This result is achieved using only 100k synthetic images, more than 100 times fewer than the 11 million images in SAM's SA-1B dataset, demonstrating the data efficiency of our approach. These findings position InsCore as a practical and license-free vision foundation model for industrial applications.
In this study, we propose a robust methodology for automatic segmentation of infected lung regions in COVID-19 CT scans using convolutional neural networks. The approach is based on a modified U-Net architecture enhanced with attention mechanisms, data augmentation, and postprocessing techniques. It achieved a Dice coefficient of 0.8658 and mean IoU of 0.8316, outperforming other methods. The dataset was sourced from public repositories and augmented for diversity. Results demonstrate superior segmentation performance. Future work includes expanding the dataset, exploring 3D segmentation, and preparing the model for clinical deployment.
The dynamic movement of the human body presents a fundamental challenge for human pose estimation and body segmentation. State-of-the-art approaches primarily rely on combining keypoint heatmaps with segmentation masks but often struggle in scenarios involving overlapping joints or rapidly changing poses during instance-level segmentation. To address these limitations, we propose Keypoints as Dynamic Centroid (KDC), a new centroid-based representation for unified human pose estimation and instance-level segmentation. KDC adopts a bottom-up paradigm to generate keypoint heatmaps for both easily distinguishable and complex keypoints and improves keypoint detection and confidence scores by introducing KeyCentroids using a keypoint disk. It leverages high-confidence keypoints as dynamic centroids in the embedding space to generate MaskCentroids, allowing for swift clustering of pixels to specific human instances during rapid body movements in live environments. Our experimental evaluations on the CrowdPose, OCHuman, and COCO benchmarks demonstrate KDC's effectiveness and generalizability in challenging scenarios in terms of both accuracy and runtime performance. The implementation is available at: https://sites.google.com/view/niazahmad/projects/kdc.
Segmentation evaluation metrics traditionally rely on binary decision logic: predictions are either correct or incorrect, based on rigid IoU thresholds. Detection--based metrics such as F1 and mAP determine correctness at the object level using fixed overlap cutoffs, while overlap--based metrics like Intersection over Union (IoU) and Dice operate at the pixel level, often overlooking instance--level structure. Panoptic Quality (PQ) attempts to unify detection and segmentation assessment, but it remains dependent on hard-threshold matching--treating predictions below the threshold as entirely incorrect. This binary framing obscures important distinctions between qualitatively different errors and fails to reward gradual model improvements. We propose SoftPQ, a flexible and interpretable instance segmentation metric that redefines evaluation as a graded continuum rather than a binary classification. SoftPQ introduces tunable upper and lower IoU thresholds to define a partial matching region and applies a sublinear penalty function to ambiguous or fragmented predictions. These extensions allow SoftPQ to exhibit smoother score behavior, greater robustness to structural segmentation errors, and more informative feedback for model development and evaluation. Through controlled perturbation experiments, we show that SoftPQ captures meaningful differences in segmentation quality that existing metrics overlook, making it a practical and principled alternative for both benchmarking and iterative model refinement.
Large vision-language models exhibit inherent capabilities to handle diverse visual perception tasks. In this paper, we introduce VisionReasoner, a unified framework capable of reasoning and solving multiple visual perception tasks within a shared model. Specifically, by designing novel multi-object cognitive learning strategies and systematic task reformulation, VisionReasoner enhances its reasoning capabilities to analyze visual inputs, and addresses diverse perception tasks in a unified framework. The model generates a structured reasoning process before delivering the desired outputs responding to user queries. To rigorously assess unified visual perception capabilities, we evaluate VisionReasoner on ten diverse tasks spanning three critical domains: detection, segmentation, and counting. Experimental results show that VisionReasoner achieves superior performance as a unified model, outperforming Qwen2.5VL by relative margins of 29.1% on COCO (detection), 22.1% on ReasonSeg (segmentation), and 15.3% on CountBench (counting).
Recently, Ultra-High Field MRI (UHF-MRI) has become more available and one of the best tools to study the brain. One common step in quantitative neuroimaging is the brain segmentation. However, the differences between UHF-MRI and 1.5-3T images are such that the automatic segmentation techniques optimized at these field strengths usually produce unsatisfactory segmentation results for UHF images. It has been particularly challenging to perform quantitative analyses as typically done with 1.5-3T data, considerably limiting the potential of UHF-MRI. Hence, we propose a novel Deep Learning (DL)-based segmentation technique called GOUHFI: Generalized and Optimized segmentation tool for Ultra-High Field Images, designed to segment UHF images of various contrasts and resolutions. For training, we used a total of 206 label maps from four datasets acquired at 3T, 7T and 9.4T. In contrast to most DL strategies, we used a previously proposed domain randomization approach, where synthetic images generated from the label maps were used for training a 3D U-Net. GOUHFI was tested on seven different datasets and compared to techniques like FastSurferVINN and CEREBRUM-7T. GOUHFI was able to the segment six contrasts and seven resolutions tested at 3T, 7T and 9.4T. Average Dice-Sorensen Similarity Coefficient (DSC) scores of 0.87, 0.84, 0.91 were computed against the ground truth segmentations at 3T, 7T and 9.4T. Moreover, GOUHFI demonstrated impressive resistance to the typical inhomogeneities observed at UHF-MRI, making it a new powerful segmentation tool that allows to apply the usual quantitative analysis pipelines also at UHF. Ultimately, GOUHFI is a promising new segmentation tool, being the first of its kind proposing a contrast- and resolution-agnostic alternative for UHF-MRI, making it the forthcoming alternative for neuroscientists working with UHF-MRI or even lower field strengths.
The hippocampus, a critical brain structure involved in memory processing and various neurodegenerative and psychiatric disorders, comprises three key subregions: the dentate gyrus (DG), Cornu Ammonis 1 (CA1), and Cornu Ammonis 3 (CA3). Accurate segmentation of these subregions from histological tissue images is essential for advancing our understanding of disease mechanisms, developmental dynamics, and therapeutic interventions. However, no existing methods address the automated segmentation of hippocampal subregions from tissue images, particularly from immunohistochemistry (IHC) images. To bridge this gap, we introduce a novel set of four comprehensive murine hippocampal IHC datasets featuring distinct staining modalities: cFos, NeuN, and multiplexed stains combining cFos, NeuN, and either {\Delta}FosB or GAD67, capturing structural, neuronal activity, and plasticity associated information. Additionally, we propose ROIsGAN, a region-guided U-Net-based generative adversarial network tailored for hippocampal subregion segmentation. By leveraging adversarial learning, ROIsGAN enhances boundary delineation and structural detail refinement through a novel region-guided discriminator loss combining Dice and binary cross-entropy loss. Evaluated across DG, CA1, and CA3 subregions, ROIsGAN consistently outperforms conventional segmentation models, achieving performance gains ranging from 1-10% in Dice score and up to 11% in Intersection over Union (IoU), particularly under challenging staining conditions. Our work establishes foundational datasets and methods for automated hippocampal segmentation, enabling scalable, high-precision analysis of tissue images in neuroscience research. Our generated datasets, proposed model as a standalone tool, and its corresponding source code are publicly available at: https://github.com/MehediAzim/ROIsGAN
Efficient and accurate multi-organ segmentation from abdominal CT volumes is a fundamental challenge in medical image analysis. Existing 3D segmentation approaches are computationally and memory intensive, often processing entire volumes that contain many anatomically irrelevant slices. Meanwhile, 2D methods suffer from class imbalance and lack cross-view contextual awareness. To address these limitations, we propose a novel, anatomically-aware slice selector pipeline that reduces input volume prior to segmentation. Our unified framework introduces a vision-language model (VLM) for cross-view organ presence detection using fused tri-slice (2.5D) representations from axial, sagittal, and coronal planes. Our proposed model acts as an "expert" in anatomical localization, reasoning over multi-view representations to selectively retain slices with high structural relevance. This enables spatially consistent filtering across orientations while preserving contextual cues. More importantly, since standard segmentation metrics such as Dice or IoU fail to measure the spatial precision of such slice selection, we introduce a novel metric, Slice Localization Concordance (SLC), which jointly captures anatomical coverage and spatial alignment with organ-centric reference slices. Unlike segmentation-specific metrics, SLC provides a model-agnostic evaluation of localization fidelity. Our model offers substantial improvement gains against several baselines across all organs, demonstrating both accurate and reliable organ-focused slice filtering. These results show that our method enables efficient and spatially consistent organ filtering, thereby significantly reducing downstream segmentation cost while maintaining high anatomical fidelity.
This work addresses the task of completely weakly supervised class-incremental learning for semantic segmentation to learn segmentation for both base and additional novel classes using only image-level labels. While class-incremental semantic segmentation (CISS) is crucial for handling diverse and newly emerging objects in the real world, traditional CISS methods require expensive pixel-level annotations for training. To overcome this limitation, partially weakly-supervised approaches have recently been proposed. However, to the best of our knowledge, this is the first work to introduce a completely weakly-supervised method for CISS. To achieve this, we propose to generate robust pseudo-labels by combining pseudo-labels from a localizer and a sequence of foundation models based on their uncertainty. Moreover, to mitigate catastrophic forgetting, we introduce an exemplar-guided data augmentation method that generates diverse images containing both previous and novel classes with guidance. Finally, we conduct experiments in three common experimental settings: 15-5 VOC, 10-10 VOC, and COCO-to-VOC, and in two scenarios: disjoint and overlap. The experimental results demonstrate that our completely weakly supervised method outperforms even partially weakly supervised methods in the 15-5 VOC and 10-10 VOC settings while achieving competitive accuracy in the COCO-to-VOC setting.
While sugar beets are stored prior to processing, they lose sugar due to factors such as microorganisms present in adherent soil and excess vegetation. Their automated visual inspection promises to aide in quality assurance and thereby increase efficiency throughout the processing chain of sugar production. In this work, we present a novel high-quality annotated dataset and two-stage method for the detection, semantic segmentation and mass estimation of post-harvest and post-storage sugar beets in monocular RGB images. We conduct extensive ablation experiments for the detection of sugar beets and their fine-grained semantic segmentation regarding damages, rot, soil adhesion and excess vegetation. For these tasks, we evaluate multiple image sizes, model architectures and encoders, as well as the influence of environmental conditions. Our experiments show an mAP50-95 of 98.8 for sugar-beet detection and an mIoU of 64.0 for the best-performing segmentation model.