Recent advances in large-scale text-to-image models have revolutionized creative fields by generating visually captivating outputs from textual prompts; however, while traditional photography offers precise control over camera settings to shape visual aesthetics - such as depth-of-field via aperture - current diffusion models typically rely on prompt engineering to mimic such effects. This approach often results in crude approximations and inadvertently alters the scene content. In this work, we propose Bokeh Diffusion, a scene-consistent bokeh control framework that explicitly conditions a diffusion model on a physical defocus blur parameter. To overcome the scarcity of paired real-world images captured under different camera settings, we introduce a hybrid training pipeline that aligns in-the-wild images with synthetic blur augmentations, providing diverse scenes and subjects as well as supervision to learn the separation of image content from lens blur. Central to our framework is our grounded self-attention mechanism, trained on image pairs with different bokeh levels of the same scene, which enables blur strength to be adjusted in both directions while preserving the underlying scene. Extensive experiments demonstrate that our approach enables flexible, lens-like blur control, supports downstream applications such as real image editing via inversion, and generalizes effectively across both Stable Diffusion and FLUX architectures.
Large-scale pre-trained Vision-Language Models (VLMs) have become essential for transfer learning across diverse tasks. However, adapting these models with limited few-shot data often leads to overfitting, diminishing their performance on new tasks. To tackle this issue, we propose a novel Multi-Modal Representation Learning (MMRL) framework that introduces a shared, learnable, and modality-agnostic representation space. MMRL projects the space tokens to text and image representation tokens, facilitating more effective multi-modal interactions. Unlike previous approaches that solely optimize class token features, MMRL integrates representation tokens at higher layers of the encoders--where dataset-specific features are more prominent--while preserving generalized knowledge in the lower layers. During training, both representation and class features are optimized, with trainable projection layer applied to the representation tokens, whereas the class token projection layer remains frozen to retain pre-trained knowledge. Furthermore, a regularization term is introduced to align the class features and text features with the zero-shot features from the frozen VLM, thereby safeguarding the model's generalization capacity. For inference, a decoupling strategy is employed, wherein both representation and class features are utilized for base classes, while only the class features, which retain more generalized knowledge, are used for new tasks. Extensive experiments across 15 datasets demonstrate that MMRL outperforms state-of-the-art methods, achieving a balanced trade-off between task-specific adaptation and generalization. Code is available at https://github.com/yunncheng/MMRL.
The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific error patterns or address cross-modal challenges. This study introduces a granular error taxonomy through systematic analysis of top 10 models on MedBench, categorizing incorrect responses into eight types: Omissions, Hallucination, Format Mismatch, Causal Reasoning Deficiency, Contextual Inconsistency, Unanswered, Output Error, and Deficiency in Medical Language Generation. Evaluation of 10 leading models reveals vulnerabilities: despite achieving 0.86 accuracy in medical knowledge recall, critical reasoning tasks show 96.3% omission, while safety ethics evaluations expose alarming inconsistency (robustness score: 0.79) under option shuffled. Our analysis uncovers systemic weaknesses in knowledge boundary enforcement and multi-step reasoning. To address these, we propose a tiered optimization strategy spanning four levels, from prompt engineering and knowledge-augmented retrieval to hybrid neuro-symbolic architectures and causal reasoning frameworks. This work establishes an actionable roadmap for developing clinically robust LLMs while redefining evaluation paradigms through error-driven insights, ultimately advancing the safety and trustworthiness of AI in high-stakes medical environments.
The COVID-19 pandemic has accelerated the adoption of telemedicine and patient messaging through electronic medical portals (patient medical advice requests, or PMARs). While these platforms enhance patient access to healthcare, they have also increased the burden on healthcare providers due to the surge in PMARs. This study seeks to develop an efficient tool for message triaging to reduce physician workload and improve patient-provider communication. We developed OPTIC (Optimizing Patient-Provider Triaging & Improving Communications in Clinical Operations), a powerful message triaging tool that utilizes GPT-4 for data labeling and BERT for model distillation. The study used a dataset of 405,487 patient messaging encounters from Johns Hopkins Medicine between January and June 2020. High-quality labeled data was generated through GPT-4-based prompt engineering, which was then used to train a BERT model to classify messages as "Admin" or "Clinical." The BERT model achieved 88.85% accuracy on the test set validated by GPT-4 labeling, with a sensitivity of 88.29%, specificity of 89.38%, and an F1 score of 0.8842. BERTopic analysis identified 81 distinct topics within the test data, with over 80% accuracy in classifying 58 topics. The system was successfully deployed through Epic's Nebula Cloud Platform, demonstrating its practical effectiveness in healthcare settings.
Large Language Model (LLM) Agents leverage the advanced reasoning capabilities of LLMs in real-world applications. To interface with an environment, these agents often rely on tools, such as web search or database APIs. As the agent provides the LLM with tool documentation along the user query, the completeness and correctness of this documentation is critical. However, tool documentation is often over-, under-, or ill-specified, impeding the agent's accuracy. Standard software testing approaches struggle to identify these errors as they are expressed in natural language. Thus, despite its importance, there currently exists no automated method to test the tool documentation for agents. To address this issue, we present ToolFuzz, the first method for automated testing of tool documentations. ToolFuzz is designed to discover two types of errors: (1) user queries leading to tool runtime errors and (2) user queries that lead to incorrect agent responses. ToolFuzz can generate a large and diverse set of natural inputs, effectively finding tool description errors at a low false positive rate. Further, we present two straightforward prompt-engineering approaches. We evaluate all three tool testing approaches on 32 common LangChain tools and 35 newly created custom tools and 2 novel benchmarks to further strengthen the assessment. We find that many publicly available tools suffer from underspecification. Specifically, we show that ToolFuzz identifies 20x more erroneous inputs compared to the prompt-engineering approaches, making it a key component for building reliable AI agents.
While a plethora of machine learning (ML) models are currently available, along with their implementation on disparate platforms, there is hardly any verifiable ML code which can be executed on public blockchains. We propose a novel approach named LMST that enables conversion of the inferencing path of an ML model as well as its weights trained off-chain into Solidity code using Large Language Models (LLMs). Extensive prompt engineering is done to achieve gas cost optimization beyond mere correctness of the produced code, while taking into consideration the capabilities and limitations of the Ethereum Virtual Machine. We have also developed a proof of concept decentralized application using the code so generated for verifying the accuracy claims of the underlying ML model. An extensive set of experiments demonstrate the feasibility of deploying ML models on blockchains through automated code translation using LLMs.
The rise of Large Language Models (LLMs) and generative visual analytics systems has transformed data-driven insights, yet significant challenges persist in accurately interpreting users' analytical and interaction intents. While language inputs offer flexibility, they often lack precision, making the expression of complex intents inefficient, error-prone, and time-intensive. To address these limitations, we investigate the design space of multimodal interactions for generative visual analytics through a literature review and pilot brainstorming sessions. Building on these insights, we introduce a highly extensible workflow that integrates multiple LLM agents for intent inference and visualization generation. We develop InterChat, a generative visual analytics system that combines direct manipulation of visual elements with natural language inputs. This integration enables precise intent communication and supports progressive, visually driven exploratory data analyses. By employing effective prompt engineering, and contextual interaction linking, alongside intuitive visualization and interaction designs, InterChat bridges the gap between user interactions and LLM-driven visualizations, enhancing both interpretability and usability. Extensive evaluations, including two usage scenarios, a user study, and expert feedback, demonstrate the effectiveness of InterChat. Results show significant improvements in the accuracy and efficiency of handling complex visual analytics tasks, highlighting the potential of multimodal interactions to redefine user engagement and analytical depth in generative visual analytics.
Cognitive biases, systematic deviations from rationality in judgment, pose significant challenges in generating objective content. This paper introduces a novel approach for real-time cognitive bias detection in user-generated text using large language models (LLMs) and advanced prompt engineering techniques. The proposed system analyzes textual data to identify common cognitive biases such as confirmation bias, circular reasoning, and hidden assumption. By designing tailored prompts, the system effectively leverages LLMs' capabilities to both recognize and mitigate these biases, improving the quality of human-generated content (e.g., news, media, reports). Experimental results demonstrate the high accuracy of our approach in identifying cognitive biases, offering a valuable tool for enhancing content objectivity and reducing the risks of biased decision-making.
We introduce the Context Compliance Attack (CCA), a novel, optimization-free method for bypassing AI safety mechanisms. Unlike current approaches -- which rely on complex prompt engineering and computationally intensive optimization -- CCA exploits a fundamental architectural vulnerability inherent in many deployed AI systems. By subtly manipulating conversation history, CCA convinces the model to comply with a fabricated dialogue context, thereby triggering restricted behavior. Our evaluation across a diverse set of open-source and proprietary models demonstrates that this simple attack can circumvent state-of-the-art safety protocols. We discuss the implications of these findings and propose practical mitigation strategies to fortify AI systems against such elementary yet effective adversarial tactics.
Large Language Models (LLMs) have shown remarkable capabilities as AI agents. However, existing methods for enhancing LLM-agent abilities often lack a focus on data quality, leading to inefficiencies and suboptimal results in both fine-tuning and prompt engineering. To address this issue, we introduce EDGE, a novel approach for identifying informative samples without needing golden answers. We propose the Guideline Effectiveness (GE) metric, which selects challenging samples by measuring the impact of human-provided guidelines in multi-turn interaction tasks. A low GE score indicates that the human expertise required for a sample is missing from the guideline, making the sample more informative. By selecting samples with low GE scores, we can improve the efficiency and outcomes of both prompt engineering and fine-tuning processes for LLMs. Extensive experiments validate the performance of our method. Our method achieves competitive results on the HotpotQA and WebShop and datasets, requiring 75\% and 50\% less data, respectively, while outperforming existing methods. We also provide a fresh perspective on the data quality of LLM-agent fine-tuning.
Multiple previous studies have reported suboptimal performance of LLMs in biomedical text mining. By analyzing failure patterns in these evaluations, we identified three primary challenges for LLMs in biomedical corpora: (1) LLMs fail to learn implicit dataset-specific nuances from supervised data, (2) The common formatting requirements of discriminative tasks limit the reasoning capabilities of LLMs particularly for LLMs that lack test-time compute, and (3) LLMs struggle to adhere to annotation guidelines and match exact schemas, which hinders their ability to understand detailed annotation requirements which is essential in biomedical annotation workflow. We experimented with prompt engineering techniques targeted to the above issues, and developed a pipeline that dynamically extracts instructions from annotation guidelines. Our results show that frontier LLMs can approach or surpass the performance of SOTA BERT-based models with minimal reliance on manually annotated data and without fine-tuning. Furthermore, we performed model distillation on a closed-source LLM, demonstrating that a BERT model trained exclusively on synthetic data annotated by LLMs can also achieve a practical performance. Based on these findings, we explored the feasibility of partially replacing manual annotation with LLMs in production scenarios for biomedical text mining.
Autonomous driving (AD) testing constitutes a critical methodology for assessing performance benchmarks prior to product deployment. The creation of segmented scenarios within a simulated environment is acknowledged as a robust and effective strategy; however, the process of tailoring these scenarios often necessitates laborious and time-consuming manual efforts, thereby hindering the development and implementation of AD technologies. In response to this challenge, we introduce Text2Scenario, a framework that leverages a Large Language Model (LLM) to autonomously generate simulation test scenarios that closely align with user specifications, derived from their natural language inputs. Specifically, an LLM, equipped with a meticulously engineered input prompt scheme functions as a text parser for test scenario descriptions, extracting from a hierarchically organized scenario repository the components that most accurately reflect the user's preferences. Subsequently, by exploiting the precedence of scenario components, the process involves sequentially matching and linking scenario representations within a Domain Specific Language corpus, ultimately fabricating executable test scenarios. The experimental results demonstrate that such prompt engineering can meticulously extract the nuanced details of scenario elements embedded within various descriptive formats, with the majority of generated scenarios aligning closely with the user's initial expectations, allowing for the efficient and precise evaluation of diverse AD stacks void of the labor-intensive need for manual scenario configuration. Project page: https://caixxuan.github.io/Text2Scenario.GitHub.io.
Identifying customer needs (CNs) is important for product management, product development, and marketing. Applications rely on professional analysts interpreting textual data (e.g., interview transcripts, online reviews) to understand the nuances of customer experience and concisely formulate "jobs to be done." The task is cognitively complex and time-consuming. Current practice facilitates the process with keyword search and machine learning but relies on human judgment to formulate CNs. We examine whether Large Language Models (LLMs) can automatically extract CNs. Because evaluating CNs requires professional judgment, we partnered with a marketing consulting firm to conduct a blind study of CNs extracted by: (1) a foundational LLM with prompt engineering only (Base LLM), (2) an LLM fine-tuned with professionally identified CNs (SFT LLM), and (3) professional analysts. The SFT LLM performs as well as or better than professional analysts when extracting CNs. The extracted CNs are well-formulated, sufficiently specific to identify opportunities, and justified by source content (no hallucinations). The SFT LLM is efficient and provides more complete coverage of CNs. The Base LLM was not sufficiently accurate or specific. Organizations can rely on SFT LLMs to reduce manual effort, enhance the precision of CN articulation, and provide improved insight for innovation and marketing strategy.
Speech-comprehension difficulties are common among older people. Standard speech tests do not fully capture such difficulties because the tests poorly resemble the context-rich, story-like nature of ongoing conversation and are typically available only in a country's dominant/official language (e.g., English), leading to inaccurate scores for native speakers of other languages. Assessments for naturalistic, story speech in multiple languages require accurate, time-efficient scoring. The current research leverages modern large language models (LLMs) in native English speakers and native speakers of 10 other languages to automate the generation of high-quality, spoken stories and scoring of speech recall in different languages. Participants listened to and freely recalled short stories (in quiet/clear and in babble noise) in their native language. LLM text-embeddings and LLM prompt engineering with semantic similarity analyses to score speech recall revealed sensitivity to known effects of temporal order, primacy/recency, and background noise, and high similarity of recall scores across languages. The work overcomes limitations associated with simple speech materials and testing of closed native-speaker groups because recall data of varying length and details can be mapped across languages with high accuracy. The full automation of speech generation and recall scoring provides an important step towards comprehension assessments of naturalistic speech with clinical applicability.
Prompt optimization aims to search for effective prompts that enhance the performance of large language models (LLMs). Although existing prompt optimization methods have discovered effective prompts, they often differ from sophisticated prompts carefully designed by human experts. Prompt design strategies, representing best practices for improving prompt performance, can be key to improving prompt optimization. Recently, a method termed the Autonomous Prompt Engineering Toolbox (APET) has incorporated various prompt design strategies into the prompt optimization process. In APET, the LLM is needed to implicitly select and apply the appropriate strategies because prompt design strategies can have negative effects. This implicit selection may be suboptimal due to the limited optimization capabilities of LLMs. This paper introduces Optimizing Prompts with sTrategy Selection (OPTS), which implements explicit selection mechanisms for prompt design. We propose three mechanisms, including a Thompson sampling-based approach, and integrate them into EvoPrompt, a well-known prompt optimizer. Experiments optimizing prompts for two LLMs, Llama-3-8B-Instruct and GPT-4o mini, were conducted using BIG-Bench Hard. Our results show that the selection of prompt design strategies improves the performance of EvoPrompt, and the Thompson sampling-based mechanism achieves the best overall results. Our experimental code is provided at https://github.com/shiralab/OPTS .
Maintaining a balanced diet is essential for overall health, yet many individuals struggle with meal planning due to nutritional complexity, time constraints, and lack of dietary knowledge. Personalized food recommendations can help address these challenges by tailoring meal plans to individual preferences, habits, and dietary restrictions. However, existing dietary recommendation systems often lack adaptability, fail to consider real-world constraints such as food ingredient availability, and require extensive user input, making them impractical for sustainable and scalable daily use. To address these limitations, we introduce NutriGen, a framework based on large language models (LLM) designed to generate personalized meal plans that align with user-defined dietary preferences and constraints. By building a personalized nutrition database and leveraging prompt engineering, our approach enables LLMs to incorporate reliable nutritional references like the USDA nutrition database while maintaining flexibility and ease-of-use. We demonstrate that LLMs have strong potential in generating accurate and user-friendly food recommendations, addressing key limitations in existing dietary recommendation systems by providing structured, practical, and scalable meal plans. Our evaluation shows that Llama 3.1 8B and GPT-3.5 Turbo achieve the lowest percentage errors of 1.55\% and 3.68\%, respectively, producing meal plans that closely align with user-defined caloric targets while minimizing deviation and improving precision. Additionally, we compared the performance of DeepSeek V3 against several established models to evaluate its potential in personalized nutrition planning.
This paper focuses on the piloting of CyberScholar, a Generative AI (GenAI) assistant tool that aims to provide feedback on writing K-12 contexts. The aim was to use GenAI to provide formative and summative feedback on students' texts in English Language Arts (ELA), Social Studies, and Modern World History. The trials discussed in this paper involved Grades 7, 8, 10, and 11 and were conducted in three schools in the Midwest and one in the Northwest of the United States. The tool used two main mechanisms: "prompt engineering" based on participant teachers' assessment rubric and "fine-tuning" a Large Language Model (LLM) from a customized corpus of teaching materials using Retrieval Augmented Generation. This paper focuses on CyberScholar's potential to enhance students' writing abilities and support teachers in diverse subject areas requiring written assignments.
This paper presents a game master AI for single-player role-playing games. The AI is designed to deliver interactive text-based narratives and experiences typically associated with multiplayer tabletop games like Dungeons & Dragons. We report on the design process and the series of experiments to improve the functionality and experience design, resulting in two functional versions of the system. While v1 of our system uses simplified prompt engineering, v2 leverages a multi-agent architecture and the ReAct framework to include reasoning and action. A comparative evaluation demonstrates that v2 as an agentic system maintains play while significantly improving modularity and game experience, including immersion and curiosity. Our findings contribute to the evolution of AI-driven interactive fiction, highlighting new avenues for enhancing solo role-playing experiences.
Recent advances in Large Language Models have led to remarkable achievements across a variety of Natural Language Processing tasks, making prompt engineering increasingly central to guiding model outputs. While manual methods can be effective, they typically rely on intuition and do not automatically refine prompts over time. In contrast, automatic prompt optimization employing heuristic-based search algorithms can systematically explore and improve prompts with minimal human oversight. This survey proposes a comprehensive taxonomy of these methods, categorizing them by where optimization occurs, what is optimized, what criteria drive the optimization, which operators generate new prompts, and which iterative search algorithms are applied. We further highlight specialized datasets and tools that support and accelerate automated prompt refinement. We conclude by discussing key open challenges pointing toward future opportunities for more robust and versatile LLM applications.
Large Language Models (LLMs) have helped programmers increase efficiency through code generation, comprehension, and repair. However, their application to large-scale projects remains challenging due to complex interdependencies and the extensive size of modern codebases. Although Knuth's concept of Literate Programming (LP) combines code and natural language to convey logic and intent, its potential for enhancing relationships in large projects has not been fully explored. In this study, we introduce the idea of Interoperable LP (ILP), which leverages literate programming principles to enhance the development of both small-scale documents and large-scale projects with LLMs. We investigate how LLMs perform under ILP-style instructions for both document-oriented tasks and entire projects. Recognizing that many researchers rely on well-structured templates to guide LLMs, we propose a concise prompt engineering method to write LP documents so LLMs can better be involved in code generation. We also examine the capacity of various LLMs to generate Scheme and Python code on the RepoBench benchmark, illustrating the advantages of our approach. Our findings indicate that ILP with LLMs can enhance LLM-based code generation in large-scale project development.