External cervical resorption (ECR) is a resorptive process affecting teeth. While in some patients, active resorption ceases and gets replaced by osseous tissue, in other cases, the resorption progresses and ultimately results in tooth loss. For proper ECR assessment, cone-beam computed tomography (CBCT) is the recommended imaging modality, enabling a 3-D characterization of these lesions. While it is possible to manually identify and measure ECR resorption in CBCT scans, this process can be time intensive and highly subject to human error. Therefore, there is an urgent need to develop an automated method to identify and quantify the severity of ECR resorption using CBCT. Here, we present a method for ECR lesion segmentation that is based on automatic, binary classification of locally extracted voxel-wise texture features. We evaluate our method on 6 longitudinal CBCT datasets and show that certain texture-features can be used to accurately detect subtle CBCT signal changes due to ECR. We also present preliminary analyses clustering texture features within a lesion to stratify the defects and identify patterns indicative of calcification. These methods are important steps in developing prognostic biomarkers to predict whether ECR will continue to progress or cease, ultimately informing treatment decisions.
While machine learning offers diverse techniques suitable for exploring various medical research questions, a cohesive synergistic framework can facilitate the integration and understanding of new approaches within unified model development and interpretation. We therefore introduce the Medical Artificial Intelligence Toolbox (MAIT), an explainable, open-source Python pipeline for developing and evaluating binary classification, regression, and survival models on tabular datasets. MAIT addresses key challenges (e.g., high dimensionality, class imbalance, mixed variable types, and missingness) while promoting transparency in reporting (TRIPOD+AI compliant). Offering automated configurations for beginners and customizable source code for experts, MAIT streamlines two primary use cases: Discovery (feature importance via unified scoring, e.g., SHapley Additive exPlanations - SHAP) and Prediction (model development and deployment with optimized solutions). Moreover, MAIT proposes new techniques including fine-tuning of probability threshold in binary classification, translation of cumulative hazard curves to binary classification, enhanced visualizations for model interpretation for mixed data types, and handling censoring through semi-supervised learning, to adapt to a wide set of data constraints and study designs. We provide detailed tutorials on GitHub, using four open-access data sets, to demonstrate how MAIT can be used to improve implementation and interpretation of ML models in medical research.
This study presents a comparative analysis of methods for detecting COVID-19 infection in radiographic images. The images, sourced from publicly available datasets, were categorized into three classes: 'normal,' 'pneumonia,' and 'COVID.' For the experiments, transfer learning was employed using eight pre-trained networks: SqueezeNet, DenseNet, ResNet, AlexNet, VGG, GoogleNet, ShuffleNet, and MobileNet. DenseNet achieved the highest accuracy of 97.64% using the ADAM optimization function in the multiclass approach. In the binary classification approach, the highest precision was 99.98%, obtained by the VGG, ResNet, and MobileNet networks. A comparative evaluation was also conducted using heat maps.
A promising tool for addressing fake news detection is Graph Neural Networks (GNNs). However, most existing GNN-based methods rely on binary classification, categorizing news as either real or fake. Additionally, traditional GNN models use a static neighborhood for each node, making them susceptible to issues like over-squashing. In this paper, we introduce a novel model named Decision-based Heterogeneous Graph Attention Network (DHGAT) for fake news detection in a semi-supervised setting. DHGAT effectively addresses the limitations of traditional GNNs by dynamically optimizing and selecting the neighborhood type for each node in every layer. It represents news data as a heterogeneous graph where nodes (news items) are connected by various types of edges. The architecture of DHGAT consists of a decision network that determines the optimal neighborhood type and a representation network that updates node embeddings based on this selection. As a result, each node learns an optimal and task-specific computational graph, enhancing both the accuracy and efficiency of the fake news detection process. We evaluate DHGAT on the LIAR dataset, a large and challenging dataset for multi-class fake news detection, which includes news items categorized into six classes. Our results demonstrate that DHGAT outperforms existing methods, improving accuracy by approximately 4% and showing robustness with limited labeled data.
The development of Generative AI Large Language Models (LLMs) raised the alarm regarding identifying content produced through generative AI or humans. In one case, issues arise when students heavily rely on such tools in a manner that can affect the development of their writing or coding skills. Other issues of plagiarism also apply. This study aims to support efforts to detect and identify textual content generated using LLM tools. We hypothesize that LLMs-generated text is detectable by machine learning (ML), and investigate ML models that can recognize and differentiate texts generated by multiple LLMs tools. We leverage several ML and Deep Learning (DL) algorithms such as Random Forest (RF), and Recurrent Neural Networks (RNN), and utilized Explainable Artificial Intelligence (XAI) to understand the important features in attribution. Our method is divided into 1) binary classification to differentiate between human-written and AI-text, and 2) multi classification, to differentiate between human-written text and the text generated by the five different LLM tools (ChatGPT, LLaMA, Google Bard, Claude, and Perplexity). Results show high accuracy in the multi and binary classification. Our model outperformed GPTZero with 98.5\% accuracy to 78.3\%. Notably, GPTZero was unable to recognize about 4.2\% of the observations, but our model was able to recognize the complete test dataset. XAI results showed that understanding feature importance across different classes enables detailed author/source profiles. Further, aiding in attribution and supporting plagiarism detection by highlighting unique stylistic and structural elements ensuring robust content originality verification.
The AUTO-PCOS Classification Challenge seeks to advance the diagnostic capabilities of artificial intelligence (AI) in identifying Polycystic Ovary Syndrome (PCOS) through automated classification of healthy and unhealthy ultrasound frames. This report outlines our methodology for building a robust AI pipeline utilizing transfer learning with the InceptionV3 architecture to achieve high accuracy in binary classification. Preprocessing steps ensured the dataset was optimized for training, validation, and testing, while interpretability methods like LIME and saliency maps provided valuable insights into the model's decision-making. Our approach achieved an accuracy of 90.52%, with precision, recall, and F1-score metrics exceeding 90% on validation data, demonstrating its efficacy. The project underscores the transformative potential of AI in healthcare, particularly in addressing diagnostic challenges like PCOS. Key findings, challenges, and recommendations for future enhancements are discussed, highlighting the pathway for creating reliable, interpretable, and scalable AI-driven medical diagnostic tools.
The detection of AI-generated faces is commonly approached as a binary classification task. Nevertheless, the resulting detectors frequently struggle to adapt to novel AI face generators, which evolve rapidly. In this paper, we describe an anomaly detection method for AI-generated faces by leveraging self-supervised learning of camera-intrinsic and face-specific features purely from photographic face images. The success of our method lies in designing a pretext task that trains a feature extractor to rank four ordinal exchangeable image file format (EXIF) tags and classify artificially manipulated face images. Subsequently, we model the learned feature distribution of photographic face images using a Gaussian mixture model. Faces with low likelihoods are flagged as AI-generated. Both quantitative and qualitative experiments validate the effectiveness of our method. Our code is available at \url{https://github.com/MZMMSEC/AIGFD_EXIF.git}.
Background: Recently, numerous foundation models pretrained on extensive data have demonstrated efficacy in disease prediction using Electronic Health Records (EHRs). However, there remains some unanswered questions on how to best utilize such models especially with very small fine-tuning cohorts. Methods: We utilized Med-BERT, an EHR-specific foundation model, and reformulated the disease binary prediction task into a token prediction task and a next visit mask token prediction task to align with Med-BERT's pretraining task format in order to improve the accuracy of pancreatic cancer (PaCa) prediction in both few-shot and fully supervised settings. Results: The reformulation of the task into a token prediction task, referred to as Med-BERT-Sum, demonstrates slightly superior performance in both few-shot scenarios and larger data samples. Furthermore, reformulating the prediction task as a Next Visit Mask Token Prediction task (Med-BERT-Mask) significantly outperforms the conventional Binary Classification (BC) prediction task (Med-BERT-BC) by 3% to 7% in few-shot scenarios with data sizes ranging from 10 to 500 samples. These findings highlight that aligning the downstream task with Med-BERT's pretraining objectives substantially enhances the model's predictive capabilities, thereby improving its effectiveness in predicting both rare and common diseases. Conclusion: Reformatting disease prediction tasks to align with the pretraining of foundation models enhances prediction accuracy, leading to earlier detection and timely intervention. This approach improves treatment effectiveness, survival rates, and overall patient outcomes for PaCa and potentially other cancers.
This paper proposes a data preparation process for managing real-world kinematic data and detecting fishing vessels. The solution is a binary classification that classifies ship trajectories into either fishing or non-fishing ships. The data used are characterized by the typical problems found in classic data mining applications using real-world data, such as noise and inconsistencies. The two classes are also clearly unbalanced in the data, a problem which is addressed using algorithms that resample the instances. For classification, a series of features are extracted from spatiotemporal data that represent the trajectories of the ships, available from sequences of Automatic Identification System (AIS) reports. These features are proposed for the modelling of ship behavior but, because they do not contain context-related information, the classification can be applied in other scenarios. Experimentation shows that the proposed data preparation process is useful for the presented classification problem. In addition, positive results are obtained using minimal information.
Face Anti-Spoofing (FAS) is essential for ensuring the security and reliability of facial recognition systems. Most existing FAS methods are formulated as binary classification tasks, providing confidence scores without interpretation. They exhibit limited generalization in out-of-domain scenarios, such as new environments or unseen spoofing types. In this work, we introduce a multimodal large language model (MLLM) framework for FAS, termed Interpretable Face Anti-Spoofing (I-FAS), which transforms the FAS task into an interpretable visual question answering (VQA) paradigm. Specifically, we propose a Spoof-aware Captioning and Filtering (SCF) strategy to generate high-quality captions for FAS images, enriching the model's supervision with natural language interpretations. To mitigate the impact of noisy captions during training, we develop a Lopsided Language Model (L-LM) loss function that separates loss calculations for judgment and interpretation, prioritizing the optimization of the former. Furthermore, to enhance the model's perception of global visual features, we design a Globally Aware Connector (GAC) to align multi-level visual representations with the language model. Extensive experiments on standard and newly devised One to Eleven cross-domain benchmarks, comprising 12 public datasets, demonstrate that our method significantly outperforms state-of-the-art methods.
Malicious URL (Uniform Resource Locator) classification is a pivotal aspect of Cybersecurity, offering defense against web-based threats. Despite deep learning's promise in this area, its advancement is hindered by two main challenges: the scarcity of comprehensive, open-source datasets and the limitations of existing models, which either lack real-time capabilities or exhibit suboptimal performance. In order to address these gaps, we introduce a novel, multi-class dataset for malicious URL classification, distinguishing between benign, phishing and malicious URLs, named DeepURLBench. The data has been rigorously cleansed and structured, providing a superior alternative to existing datasets. Notably, the multi-class approach enhances the performance of deep learning models, as compared to a standard binary classification approach. Additionally, we propose improvements to string-based URL classifiers, applying these enhancements to URLNet. Key among these is the integration of DNS-derived features, which enrich the model's capabilities and lead to notable performance gains while preserving real-time runtime efficiency-achieving an effective balance for cybersecurity applications.
Digital screening and monitoring applications can aid providers in the management of behavioral health conditions. We explore deep language models for detecting depression, anxiety, and their co-occurrence from conversational speech collected during 16k user interactions with an application. Labels come from PHQ-8 and GAD-7 results also collected by the application. We find that results for binary classification range from 0.86 to 0.79 AUC, depending on condition and co-occurrence. Best performance is achieved when a user has either both or neither condition, and we show that this result is not attributable to data skew. Finally, we find evidence suggesting that underlying word sequence cues may be more salient for depression than for anxiety.
Weakly Supervised Monitoring Anomaly Detection (WSMAD) utilizes weak supervision learning to identify anomalies, a critical task for smart city monitoring. However, existing multimodal approaches often fail to meet the real-time and interpretability requirements of edge devices due to their complexity. This paper presents TCVADS (Two-stage Cross-modal Video Anomaly Detection System), which leverages knowledge distillation and cross-modal contrastive learning to enable efficient, accurate, and interpretable anomaly detection on edge devices.TCVADS operates in two stages: coarse-grained rapid classification and fine-grained detailed analysis. In the first stage, TCVADS extracts features from video frames and inputs them into a time series analysis module, which acts as the teacher model. Insights are then transferred via knowledge distillation to a simplified convolutional network (student model) for binary classification. Upon detecting an anomaly, the second stage is triggered, employing a fine-grained multi-class classification model. This stage uses CLIP for cross-modal contrastive learning with text and images, enhancing interpretability and achieving refined classification through specially designed triplet textual relationships. Experimental results demonstrate that TCVADS significantly outperforms existing methods in model performance, detection efficiency, and interpretability, offering valuable contributions to smart city monitoring applications.
Machine learning systems increasingly drive innovation across scientific fields and industry, yet challenges in compute overhead, specifically during inference, limit their scalability and sustainability. Responsible AI guardrails, essential for ensuring fairness, transparency, and privacy, further exacerbate these computational demands. This study addresses critical gaps in the literature, chiefly the lack of generalized predictive techniques for latency and energy consumption, limited cross-comparisons of classifiers, and unquantified impacts of RAI guardrails on inference performance. Using Theory Construction Methodology, this work constructed a model-agnostic theoretical framework for predicting latency and energy consumption in binary classification models during inference. The framework synthesizes classifier characteristics, dataset properties, and RAI guardrails into a unified analytical instrument. Two predictive equations are derived that capture the interplay between these factors while offering generalizability across diverse classifiers. The proposed framework provides foundational insights for designing efficient, responsible ML systems. It enables researchers to benchmark and optimize inference performance and assists practitioners in deploying scalable solutions. Finally, this work establishes a theoretical foundation for balancing computational efficiency with ethical AI principles, paving the way for future empirical validation and broader applications.
This work focuses on two subtasks related to hate speech detection and target identification in Devanagari-scripted languages, specifically Hindi, Marathi, Nepali, Bhojpuri, and Sanskrit. Subtask B involves detecting hate speech in online text, while Subtask C requires identifying the specific targets of hate speech, such as individuals, organizations, or communities. We propose the MultilingualRobertaClass model, a deep neural network built on the pretrained multilingual transformer model ia-multilingual-transliterated-roberta, optimized for classification tasks in multilingual and transliterated contexts. The model leverages contextualized embeddings to handle linguistic diversity, with a classifier head for binary classification. We received 88.40% accuracy in Subtask B and 66.11% accuracy in Subtask C, in the test set.
Speech-based algorithms have gained interest for the management of behavioral health conditions such as depression. We explore a speech-based transfer learning approach that uses a lightweight encoder and that transfers only the encoder weights, enabling a simplified run-time model. Our study uses a large data set containing roughly two orders of magnitude more speakers and sessions than used in prior work. The large data set enables reliable estimation of improvement from transfer learning. Results for the prediction of PHQ-8 labels show up to 27% relative performance gains for binary classification; these gains are statistically significant with a p-value close to zero. Improvements were also found for regression. Additionally, the gain from transfer learning does not appear to require strong source task performance. Results suggest that this approach is flexible and offers promise for efficient implementation.
Imbalanced binary classification problems arise in many fields of study. When using machine learning models for these problems, it is common to subsample the majority class (i.e., undersampling) to create a (more) balanced dataset for model training. This biases the model's predictions because the model learns from a dataset that does not follow the same data generating process as new data. One way of accounting for this bias is to analytically map the resulting predictions to new values based on the sampling rate for the majority class, which was used to create the training dataset. While this approach may work well for some machine learning models, we have found that calibrating a random forest this way has unintended negative consequences, including prevalence estimates that can be upwardly biased. These prevalence estimates depend on both i) the number of predictors considered at each split in the random forest; and ii) the sampling rate used. We explain the former using known properties of random forests and analytical calibration. However, in investigating the latter issue, we made a surprising discovery - contrary to the widespread belief that decision trees are biased towards the majority class, they actually can be biased towards the minority class.
Machine learning continues to grow in popularity in academia, in industry, and is increasingly used in other fields. However, most of the common metrics used to evaluate even simple binary classification models have shortcomings that are neither immediately obvious nor consistently taught to practitioners. Here we present Interactive Classification Metrics (ICM), an application to visualize and explore the relationships between different evaluation metrics. The user changes the distribution statistics and explores corresponding changes across a suite of evaluation metrics. The interactive, graphical nature of this tool emphasizes the tradeoffs of each metric without the overhead of data wrangling and model training. The goals of this application are: (1) to aid practitioners in the ever-expanding machine learning field to choose the most appropriate evaluation metrics for their classification problem; (2) to promote careful attention to interpretation that is required even in the simplest scenarios like binary classification. Our application is publicly available for free under the MIT license as a Python package on PyPI at https://pypi.org/project/interactive-classification-metrics and on GitHub at https://github.com/davhbrown/interactive_classification_metrics.
Unsupervised anomaly detection methods can identify surface defects in industrial images by leveraging only normal samples for training. Due to the risk of overfitting when learning from a single class, anomaly synthesis strategies are introduced to enhance detection capability by generating artificial anomalies. However, existing strategies heavily rely on anomalous textures from auxiliary datasets. Moreover, their limitations in the coverage and directionality of anomaly synthesis may result in a failure to capture useful information and lead to significant redundancy. To address these issues, we propose a novel Progressive Boundary-guided Anomaly Synthesis (PBAS) strategy, which can directionally synthesize crucial feature-level anomalies without auxiliary textures. It consists of three core components: Approximate Boundary Learning (ABL), Anomaly Feature Synthesis (AFS), and Refined Boundary Optimization (RBO). To make the distribution of normal samples more compact, ABL first learns an approximate decision boundary by center constraint, which improves the center initialization through feature alignment. AFS then directionally synthesizes anomalies with more flexible scales guided by the hypersphere distribution of normal features. Since the boundary is so loose that it may contain real anomalies, RBO refines the decision boundary through the binary classification of artificial anomalies and normal features. Experimental results show that our method achieves state-of-the-art performance and the fastest detection speed on three widely used industrial datasets, including MVTec AD, VisA, and MPDD. The code will be available at: https://github.com/cqylunlun/PBAS.
We study first-order algorithms that are uniformly stable for empirical risk minimization (ERM) problems that are convex and smooth with respect to $p$-norms, $p \geq 1$. We propose a black-box reduction method that, by employing properties of uniformly convex regularizers, turns an optimization algorithm for H\"older smooth convex losses into a uniformly stable learning algorithm with optimal statistical risk bounds on the excess risk, up to a constant factor depending on $p$. Achieving a black-box reduction for uniform stability was posed as an open question by (Attia and Koren, 2022), which had solved the Euclidean case $p=2$. We explore applications that leverage non-Euclidean geometry in addressing binary classification problems.