Existing studies on bundle construction have relied merely on user feedback via bipartite graphs or enhanced item representations using semantic information. These approaches fail to capture elaborate relations hidden in real-world bundle structures, resulting in suboptimal bundle representations. To overcome this limitation, we propose RaMen, a novel method that provides a holistic multi-strategy approach for bundle construction. RaMen utilizes both intrinsic (characteristics) and extrinsic (collaborative signals) information to model bundle structures through Explicit Strategy-aware Learning (ESL) and Implicit Strategy-aware Learning (ISL). ESL employs task-specific attention mechanisms to encode multi-modal data and direct collaborative relations between items, thereby explicitly capturing essential bundle features. Moreover, ISL computes hyperedge dependencies and hypergraph message passing to uncover shared latent intents among groups of items. Integrating diverse strategies enables RaMen to learn more comprehensive and robust bundle representations. Meanwhile, Multi-strategy Alignment & Discrimination module is employed to facilitate knowledge transfer between learning strategies and ensure discrimination between items/bundles. Extensive experiments demonstrate the effectiveness of RaMen over state-of-the-art models on various domains, justifying valuable insights into complex item set problems.
Crop mapping involves identifying and classifying crop types using spatial data, primarily derived from remote sensing imagery. This study presents the first comprehensive review of large-scale, pixel-wise crop mapping workflows, encompassing both conventional supervised methods and emerging transfer learning approaches. To identify the optimal supervised crop mapping workflows, we conducted systematic experiments, comparing six widely adopted satellite image-based preprocessing methods, alongside eleven supervised pixel-wise classification models. Additionally, we assessed the synergistic impact of varied training sample sizes and variable combinations. Moreover, we identified optimal transfer learning techniques for different magnitudes of domain shift. The evaluation of best methods was conducted across five diverse agricultural sites. Landsat 8 served as the primary satellite data source. Labels come from CDL trusted pixels and field surveys. Our findings reveal three key insights. First, fine-scale interval preprocessing paired with Transformer models consistently delivered optimal performance for both supervised and transferable workflows. RF offered rapid training and competitive performance in conventional supervised learning and direct transfer to similar domains. Second, transfer learning techniques enhanced workflow adaptability, with UDA being effective for homogeneous crop classes while fine-tuning remains robust across diverse scenarios. Finally, workflow choice depends heavily on the availability of labeled samples. With a sufficient sample size, supervised training typically delivers more accurate and generalizable results. Below a certain threshold, transfer learning that matches the level of domain shift is a viable alternative to achieve crop mapping. Repository: Best-Practices-for-Large-Scale-Pixel-Wise-Crop-Mapping-and-Transfer-Learning-Workflows
Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated whole slide image analysis requires multiple instance learning (MIL) frameworks due to the gigapixel scale of the slides. The diversity among histopathology FMs has highlighted the need to design real-world challenges for evaluating their effectiveness. To bridge this gap, our work presents a novel benchmark for evaluating histopathology FMs as patch-level feature extractors within a MIL classification framework. For that purpose, we leverage the AI4SkIN dataset, a multi-center cohort encompassing slides with challenging cutaneous spindle cell neoplasm subtypes. We also define the Foundation Model - Silhouette Index (FM-SI), a novel metric to measure model consistency against distribution shifts. Our experimentation shows that extracting less biased features enhances classification performance, especially in similarity-based MIL classifiers.
Multi-task learning (MTL) has shown effectiveness in exploiting shared information across tasks to improve generalization. MTL assumes tasks share similarities that can improve performance. In addition, boosting algorithms have demonstrated exceptional performance across diverse learning problems, primarily due to their ability to focus on hard-to-learn instances and iteratively reduce residual errors. This makes them a promising approach for learning multi-task problems. However, real-world MTL scenarios often involve tasks that are not well-aligned (known as outlier or adversarial tasks), which do not share beneficial similarities with others and can, in fact, deteriorate the performance of the overall model. To overcome this challenge, we propose Robust-Multi-Task Gradient Boosting (R-MTGB), a novel boosting framework that explicitly models and adapts to task heterogeneity during training. R-MTGB structures the learning process into three sequential blocks: (1) learning shared patterns, (2) partitioning tasks into outliers and non-outliers with regularized parameters, and (3) fine-tuning task-specific predictors. This architecture enables R-MTGB to automatically detect and penalize outlier tasks while promoting effective knowledge transfer among related tasks. Our method integrates these mechanisms seamlessly within gradient boosting, allowing robust handling of noisy or adversarial tasks without sacrificing accuracy. Extensive experiments on both synthetic benchmarks and real-world datasets demonstrate that our approach successfully isolates outliers, transfers knowledge, and consistently reduces prediction errors for each task individually, and achieves overall performance gains across all tasks. These results highlight robustness, adaptability, and reliable convergence of R-MTGB in challenging MTL environments.
This survey reviews prompt tuning, a parameter-efficient approach for adapting language models by prepending trainable continuous vectors while keeping the model frozen. We classify existing approaches into two categories: direct prompt learning and transfer learning. Direct prompt learning methods include: general optimization approaches, encoder-based methods, decomposition strategies, and mixture-of-experts frameworks. Transfer learning methods consist of: general transfer approaches, encoder-based methods, and decomposition strategies. For each method, we analyze method designs, innovations, insights, advantages, and disadvantages, with illustrative visualizations comparing different frameworks. We identify challenges in computational efficiency and training stability, and discuss future directions in improving training robustness and broadening application scope.
Pediatric medical imaging presents unique challenges due to significant anatomical and developmental differences compared to adults. Direct application of segmentation models trained on adult data often yields suboptimal performance, particularly for small or rapidly evolving structures. To address these challenges, several strategies leveraging the nnU-Net framework have been proposed, differing along four key axes: (i) the fingerprint dataset (adult, pediatric, or a combination thereof) from which the Training Plan -including the network architecture-is derived; (ii) the Learning Set (adult, pediatric, or mixed), (iii) Data Augmentation parameters, and (iv) the Transfer learning method (finetuning versus continual learning). In this work, we introduce PSAT (Pediatric Segmentation Approaches via Adult Augmentations and Transfer learning), a systematic study that investigates the impact of these axes on segmentation performance. We benchmark the derived strategies on two pediatric CT datasets and compare them with state-of-theart methods, including a commercial radiotherapy solution. PSAT highlights key pitfalls and provides actionable insights for improving pediatric segmentation. Our experiments reveal that a training plan based on an adult fingerprint dataset is misaligned with pediatric anatomy-resulting in significant performance degradation, especially when segmenting fine structures-and that continual learning strategies mitigate institutional shifts, thus enhancing generalization across diverse pediatric datasets. The code is available at https://github.com/ICANS-Strasbourg/PSAT.
As language agents tackle increasingly complex tasks, they struggle with effective error correction and experience reuse across domains. We introduce Agent KB, a hierarchical experience framework that enables complex agentic problem solving via a novel Reason-Retrieve-Refine pipeline. Agent KB addresses a core limitation: agents traditionally cannot learn from each other's experiences. By capturing both high-level strategies and detailed execution logs, Agent KB creates a shared knowledge base that enables cross-agent knowledge transfer. Evaluated on the GAIA benchmark, Agent KB improves success rates by up to 16.28 percentage points. On the most challenging tasks, Claude-3 improves from 38.46% to 57.69%, while GPT-4 improves from 53.49% to 73.26% on intermediate tasks. On SWE-bench code repair, Agent KB enables Claude-3 to improve from 41.33% to 53.33%. Our results suggest that Agent KB provides a modular, framework-agnostic infrastructure for enabling agents to learn from past experiences and generalize successful strategies to new tasks.
This paper presents our submission to Task 1, Subjectivity Detection, of the CheckThat! Lab at CLEF 2025. We investigate the effectiveness of transfer-learning and stylistic data augmentation to improve classification of subjective and objective sentences in English news text. Our approach contrasts fine-tuning of pre-trained encoders and transfer-learning of fine-tuned transformer on related tasks. We also introduce a controlled augmentation pipeline using GPT-4o to generate paraphrases in predefined subjectivity styles. To ensure label and style consistency, we employ the same model to correct and refine the generated samples. Results show that transfer-learning of specified encoders outperforms fine-tuning general-purpose ones, and that carefully curated augmentation significantly enhances model robustness, especially in detecting subjective content. Our official submission placed us $16^{th}$ of 24 participants. Overall, our findings underscore the value of combining encoder specialization with label-consistent augmentation for improved subjectivity detection. Our code is available at https://github.com/dsgt-arc/checkthat-2025-subject.
Transfer learning in Reinforcement Learning (RL) enables agents to leverage knowledge from source tasks to accelerate learning in target tasks. While prior work, such as the Attend, Adapt, and Transfer (A2T) framework, addresses negative transfer and selective transfer, other critical challenges remain underexplored. This paper introduces the Generalized Adaptive Transfer Network (GATN), a deep RL architecture designed to tackle task generalization across domains, robustness to environmental changes, and computational efficiency in transfer. GATN employs a domain-agnostic representation module, a robustness-aware policy adapter, and an efficient transfer scheduler to achieve these goals. We evaluate GATN on diverse benchmarks, including Atari 2600, MuJoCo, and a custom chatbot dialogue environment, demonstrating superior performance in cross-domain generalization, resilience to dynamic environments, and reduced computational overhead compared to baselines. Our findings suggest GATN is a versatile framework for real-world RL applications, such as adaptive chatbots and robotic control.
Zero-shot skeleton-based action recognition aims to classify unseen skeleton-based human actions without prior exposure to such categories during training. This task is extremely challenging due to the difficulty in generalizing from known to unknown actions. Previous studies typically use two-stage training: pre-training skeleton encoders on seen action categories using cross-entropy loss and then aligning pre-extracted skeleton and text features, enabling knowledge transfer to unseen classes through skeleton-text alignment and language models' generalization. However, their efficacy is hindered by 1) insufficient discrimination for skeleton features, as the fixed skeleton encoder fails to capture necessary alignment information for effective skeleton-text alignment; 2) the neglect of alignment bias between skeleton and unseen text features during testing. To this end, we propose a prototype-guided feature alignment paradigm for zero-shot skeleton-based action recognition, termed PGFA. Specifically, we develop an end-to-end cross-modal contrastive training framework to improve skeleton-text alignment, ensuring sufficient discrimination for skeleton features. Additionally, we introduce a prototype-guided text feature alignment strategy to mitigate the adverse impact of the distribution discrepancy during testing. We provide a theoretical analysis to support our prototype-guided text feature alignment strategy and empirically evaluate our overall PGFA on three well-known datasets. Compared with the top competitor SMIE method, our PGFA achieves absolute accuracy improvements of 22.96%, 12.53%, and 18.54% on the NTU-60, NTU-120, and PKU-MMD datasets, respectively.
Federated learning(FL) is used for distributed scenarios to train artificial intelligence(AI) models while ensuring users' privacy. In federated learning scenario, the server generally never knows about users' data. This type of concept makes the AI training process efficient in terms of data privacy. However, regarding model performance, federated AI models may not sufficiently satisfy AI users' expectations. Furthermore, AI users have a wide range of different needs. It is not easy to satisfy the whole users needs. These types of issues can be addressed through AI model optimization, fine-tuning, or personalization to achieve optimal model performance. To address model optimization challenges, we propose reference model-based federated learning for optimal fine-tuning, which overcomes catastrophic forgetting in each round. This method is derived from Bayesian parameter-efficient transfer learning, which includes an optimal proximal term and enables overcoming the catastrophic forgetting issue in each round by utilizing a reference model that incorporates previous model parameters. As a result, this method achieves both high model performance and low computing cost.
Atypical mitoses mark a deviation in the cell division process that can be an independent prognostically relevant marker for tumor malignancy. However, their identification remains challenging due to low prevalence, at times subtle morphological differences from normal mitoses, low inter-rater agreement among pathologists, and class imbalance in datasets. Building on the Atypical Mitosis dataset for Breast Cancer (AMi-Br), this study presents a comprehensive benchmark comparing deep learning approaches for automated atypical mitotic figure (AMF) classification, including baseline models, foundation models with linear probing, and foundation models fine-tuned with low-rank adaptation (LoRA). For rigorous evaluation, we further introduce two new hold-out AMF datasets - AtNorM-Br, a dataset of mitoses from the The TCGA breast cancer cohort, and AtNorM-MD, a multi-domain dataset of mitoses from the MIDOG++ training set. We found average balanced accuracy values of up to 0.8135, 0.7696, and 0.7705 on the in-domain AMi-Br and the out-of-domain AtNorm-Br and AtNorM-MD datasets, respectively, with the results being particularly good for LoRA-based adaptation of the Virchow-line of foundation models. Our work shows that atypical mitosis classification, while being a challenging problem, can be effectively addressed through the use of recent advances in transfer learning and model fine-tuning techniques. We make available all code and data used in this paper in this github repository: https://github.com/DeepMicroscopy/AMi-Br_Benchmark.
Cross-domain time series imputation is an underexplored data-centric research task that presents significant challenges, particularly when the target domain suffers from high missing rates and domain shifts in temporal dynamics. Existing time series imputation approaches primarily focus on the single-domain setting, which cannot effectively adapt to a new domain with domain shifts. Meanwhile, conventional domain adaptation techniques struggle with data incompleteness, as they typically assume the data from both source and target domains are fully observed to enable adaptation. For the problem of cross-domain time series imputation, missing values introduce high uncertainty that hinders distribution alignment, making existing adaptation strategies ineffective. Specifically, our proposed solution tackles this problem from three perspectives: (i) Data: We introduce a frequency-based time series interpolation strategy that integrates shared spectral components from both domains while retaining domain-specific temporal structures, constructing informative priors for imputation. (ii) Model: We design a diffusion-based imputation model that effectively learns domain-shared representations and captures domain-specific temporal dependencies with dedicated denoising networks. (iii) Algorithm: We further propose a cross-domain consistency alignment strategy that selectively regularizes output-level domain discrepancies, enabling effective knowledge transfer while preserving domain-specific characteristics. Extensive experiments on three real-world datasets demonstrate the superiority of our proposed approach. Our code implementation is available here.
Transfer learning is a cornerstone of modern machine learning, promising a way to adapt models pretrained on a broad mix of data to new tasks with minimal new data. However, a significant challenge remains in ensuring that transferred features are sufficient to handle unseen datasets, amplified by the difficulty of quantifying whether two tasks are "related". To address these challenges, we evaluate model transfer from a pretraining mixture to each of its component tasks, assessing whether pretrained features can match the performance of task-specific direct training. We identify a fundamental limitation in deep learning models -- an "information saturation bottleneck" -- where networks fail to learn new features once they encode similar competing features during training. When restricted to learning only a subset of key features during pretraining, models will permanently lose critical features for transfer and perform inconsistently on data distributions, even components of the training mixture. Empirical evidence from published studies suggests that this phenomenon is pervasive in deep learning architectures -- factors such as data distribution or ordering affect the features that current representation learning methods can learn over time. This study suggests that relying solely on large-scale networks may not be as effective as focusing on task-specific training, when available. We propose richer feature representations as a potential solution to better generalize across new datasets and, specifically, present existing methods alongside a novel approach, the initial steps towards addressing this challenge.
There is growing interest in extending average treatment effect (ATE) estimation to incorporate non-tabular data, such as images and text, which may act as sources of confounding. Neglecting these effects risks biased results and flawed scientific conclusions. However, incorporating non-tabular data necessitates sophisticated feature extractors, often in combination with ideas of transfer learning. In this work, we investigate how latent features from pre-trained neural networks can be leveraged to adjust for sources of confounding. We formalize conditions under which these latent features enable valid adjustment and statistical inference in ATE estimation, demonstrating results along the example of double machine learning. We discuss critical challenges inherent to latent feature learning and downstream parameter estimation arising from the high dimensionality and non-identifiability of representations. Common structural assumptions for obtaining fast convergence rates with additive or sparse linear models are shown to be unrealistic for latent features. We argue, however, that neural networks are largely insensitive to these issues. In particular, we show that neural networks can achieve fast convergence rates by adapting to intrinsic notions of sparsity and dimension of the learning problem.
Transferring extensive knowledge from relevant social networks has emerged as a promising solution to overcome label scarcity in detecting social bots and other anomalies with GNN-based models. However, effective transfer faces two critical challenges. Firstly, the network heterophily problem, which is caused by bots hiding malicious behaviors via indiscriminately interacting with human users, hinders the model's ability to learn sufficient and accurate bot-related knowledge from source domains. Secondly, single-source transfer might lead to inferior and unstable results, as the source network may embody weak relevance to the task and provide limited knowledge. To address these challenges, we explore multiple source domains and propose a multi-source graph domain adaptation model named \textit{BotTrans}. We initially leverage the labeling knowledge shared across multiple source networks to establish a cross-source-domain topology with increased network homophily. We then aggregate cross-domain neighbor information to enhance the discriminability of source node embeddings. Subsequently, we integrate the relevance between each source-target pair with model optimization, which facilitates knowledge transfer from source networks that are more relevant to the detection task. Additionally, we propose a refinement strategy to improve detection performance by utilizing semantic knowledge within the target domain. Extensive experiments on real-world datasets demonstrate that \textit{BotTrans} outperforms the existing state-of-the-art methods, revealing its efficacy in leveraging multi-source knowledge when the target detection task is unlabeled.
Machine learning has promised to change the landscape of laboratory chemistry, with impressive results in molecular property prediction and reaction retro-synthesis. However, chemical datasets are often inaccessible to the machine learning community as they tend to require cleaning, thorough understanding of the chemistry, or are simply not available. In this paper, we introduce a novel dataset for yield prediction, providing the first-ever transient flow dataset for machine learning benchmarking, covering over 1200 process conditions. While previous datasets focus on discrete parameters, our experimental set-up allow us to sample a large number of continuous process conditions, generating new challenges for machine learning models. We focus on solvent selection, a task that is particularly difficult to model theoretically and therefore ripe for machine learning applications. We showcase benchmarking for regression algorithms, transfer-learning approaches, feature engineering, and active learning, with important applications towards solvent replacement and sustainable manufacturing.
We present a novel federated multi-task learning method that leverages cross-client similarity to enable personalized learning for each client. To avoid transmitting the entire model to the parameter server, we propose a communication-efficient scheme that introduces a feature anchor, a compact vector representation that summarizes the features learned from the client's local classes. This feature anchor is shared with the server to account for local clients' distribution. In addition, the clients share the classification heads, a lightweight linear layer, and perform a graph-based regularization to enable collaboration among clients. By modeling collaboration between clients as a dynamic graph and continuously updating and refining this graph, we can account for any drift from the clients. To ensure beneficial knowledge transfer and prevent negative collaboration, we leverage a community detection-based approach that partitions this dynamic graph into homogeneous communities, maximizing the sum of task similarities, represented as the graph edges' weights, within each community. This mechanism restricts collaboration to highly similar clients within their formed communities, ensuring positive interaction and preserving personalization. Extensive experiments on two heterogeneous datasets demonstrate that our method significantly outperforms state-of-the-art baselines. Furthermore, we show that our method exhibits superior computation and communication efficiency and promotes fairness across clients.
Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly supervised clinical datasets. In contrast to fields such as NLP and conventional computer vision, where transfer learning is widely used to address data scarcity, the transferability of MIL models remains poorly understood. In this study, we systematically evaluate the transfer learning capabilities of pretrained MIL models by assessing 11 models across 21 pretraining tasks for morphological and molecular subtype prediction. Our results show that pretrained MIL models, even when trained on different organs than the target task, consistently outperform models trained from scratch. Moreover, pretraining on pancancer datasets enables strong generalization across organs and tasks, outperforming slide foundation models while using substantially less pretraining data. These findings highlight the robust adaptability of MIL models and demonstrate the benefits of leveraging transfer learning to boost performance in CPath. Lastly, we provide a resource which standardizes the implementation of MIL models and collection of pretrained model weights on popular CPath tasks, available at https://github.com/mahmoodlab/MIL-Lab
In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised learning (SSL) enhances the utilization of unlabeled data by facilitating knowledge transfer, significantly improving the performance of fully supervised models and emerging as a highly promising research direction in medical image analysis. Inspired by the ability of Vision Foundation Models (e.g., SAM-2) to provide rich prior knowledge, we propose SSS (Semi-Supervised SAM-2), a novel approach that leverages SAM-2's robust feature extraction capabilities to uncover latent knowledge in unlabeled medical images, thus effectively enhancing feature support for fully supervised medical image segmentation. Specifically, building upon the single-stream "weak-to-strong" consistency regularization framework, this paper introduces a Discriminative Feature Enhancement (DFE) mechanism to further explore the feature discrepancies introduced by various data augmentation strategies across multiple views. By leveraging feature similarity and dissimilarity across multi-scale augmentation techniques, the method reconstructs and models the features, thereby effectively optimizing the salient regions. Furthermore, a prompt generator is developed that integrates Physical Constraints with a Sliding Window (PCSW) mechanism to generate input prompts for unlabeled data, fulfilling SAM-2's requirement for additional prompts. Extensive experiments demonstrate the superiority of the proposed method for semi-supervised medical image segmentation on two multi-label datasets, i.e., ACDC and BHSD. Notably, SSS achieves an average Dice score of 53.15 on BHSD, surpassing the previous state-of-the-art method by +3.65 Dice. Code will be available at https://github.com/AIGeeksGroup/SSS.