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arXiv:2506.09403공식 코드 · Papers with Code

SRPL-SFDA: SAM-Guided Reliable Pseudo-Labels for Source-Free Domain Adaptation in Medical Image Segmentation

Domain Adaptation (DA) is crucial for robust deployment of medical image segmentation models when applied to new clinical centers with significant domain shifts. Source-Free Domain Adaptation (SFDA) is appealing as it can deal with privacy concerns and access constraints on source-domain data during adaptation to target-domain data. However, SFDA faces challenges such as insufficient supervision in the target domain with unlabeled images. In this work, we propose a Segment Anything Model (SAM)-guided Reliable Pseudo-Labels method for SFDA (SRPL-SFDA) with three key components: 1) Test-Time Tri-branch Intensity Enhancement (T3IE) that not only improves quality of raw pseudo-labels in the target domain, but also leads to SAM-compatible inputs with three channels to better leverage SAM's zero-shot inference ability for refining the pseudo-labels; 2) A reliable pseudo-label selection module that rejects low-quality pseudo-labels based on Consistency of Multiple SAM Outputs (CMSO) under input perturbations with T3IE; and 3) A reliability-aware training procedure in the unlabeled target domain where reliable pseudo-labels are used for supervision and unreliable parts are regularized by entropy minimization. Experiments conducted on two multi-domain medical image segmentation datasets for fetal brain and the prostate respectively demonstrate that: 1) SRPL-SFDA effectively enhances pseudo-label quality in the unlabeled target domain, and improves SFDA performance by leveraging the reliability-aware training; 2) SRPL-SFDA outperformed state-of-the-art SFDA methods, and its performance is close to that of supervised training in the target domain. The code of this work is available online: https://github.com/HiLab-git/SRPL-SFDA.

arXiv:2505.24216공식 코드 · Papers with Code

Shuffle PatchMix Augmentation with Confidence-Margin Weighted Pseudo-Labels for Enhanced Source-Free Domain Adaptation

This work investigates Source-Free Domain Adaptation (SFDA), where a model adapts to a target domain without access to source data. A new augmentation technique, Shuffle PatchMix (SPM), and a novel reweighting strategy are introduced to enhance performance. SPM shuffles and blends image patches to generate diverse and challenging augmentations, while the reweighting strategy prioritizes reliable pseudo-labels to mitigate label noise. These techniques are particularly effective on smaller datasets like PACS, where overfitting and pseudo-label noise pose greater risks. State-of-the-art results are achieved on three major benchmarks: PACS, VisDA-C, and DomainNet-126. Notably, on PACS, improvements of 7.3% (79.4% to 86.7%) and 7.2% are observed in single-target and multi-target settings, respectively, while gains of 2.8% and 0.7% are attained on DomainNet-126 and VisDA-C. This combination of advanced augmentation and robust pseudo-label reweighting establishes a new benchmark for SFDA. The code is available at: https://github.com/PrasannaPulakurthi/SPM

arXiv:2505.09927공식 코드 · Papers with Code

DDFP: Data-dependent Frequency Prompt for Source Free Domain Adaptation of Medical Image Segmentation

Domain adaptation addresses the challenge of model performance degradation caused by domain gaps. In the typical setup for unsupervised domain adaptation, labeled data from a source domain and unlabeled data from a target domain are used to train a target model. However, access to labeled source domain data, particularly in medical datasets, can be restricted due to privacy policies. As a result, research has increasingly shifted to source-free domain adaptation (SFDA), which requires only a pretrained model from the source domain and unlabeled data from the target domain data for adaptation. Existing SFDA methods often rely on domain-specific image style translation and self-supervision techniques to bridge the domain gap and train the target domain model. However, the quality of domain-specific style-translated images and pseudo-labels produced by these methods still leaves room for improvement. Moreover, training the entire model during adaptation can be inefficient under limited supervision. In this paper, we propose a novel SFDA framework to address these challenges. Specifically, to effectively mitigate the impact of domain gap in the initial training phase, we introduce preadaptation to generate a preadapted model, which serves as an initialization of target model and allows for the generation of high-quality enhanced pseudo-labels without introducing extra parameters. Additionally, we propose a data-dependent frequency prompt to more effectively translate target domain images into a source-like style. To further enhance adaptation, we employ a style-related layer fine-tuning strategy, specifically designed for SFDA, to train the target model using the prompted target domain images and pseudo-labels. Extensive experiments on cross-modality abdominal and cardiac SFDA segmentation tasks demonstrate that our proposed method outperforms existing state-of-the-art methods.

arXiv:2505.08527공식 코드 · Papers with Code

Leveraging Segment Anything Model for Source-Free Domain Adaptation via Dual Feature Guided Auto-Prompting

Source-free domain adaptation (SFDA) for segmentation aims at adapting a model trained in the source domain to perform well in the target domain with only the source model and unlabeled target data.Inspired by the recent success of Segment Anything Model (SAM) which exhibits the generality of segmenting images of various modalities and in different domains given human-annotated prompts like bounding boxes or points, we for the first time explore the potentials of Segment Anything Model for SFDA via automatedly finding an accurate bounding box prompt. We find that the bounding boxes directly generated with existing SFDA approaches are defective due to the domain gap.To tackle this issue, we propose a novel Dual Feature Guided (DFG) auto-prompting approach to search for the box prompt. Specifically, the source model is first trained in a feature aggregation phase, which not only preliminarily adapts the source model to the target domain but also builds a feature distribution well-prepared for box prompt search. In the second phase, based on two feature distribution observations, we gradually expand the box prompt with the guidance of the target model feature and the SAM feature to handle the class-wise clustered target features and the class-wise dispersed target features, respectively. To remove the potentially enlarged false positive regions caused by the over-confident prediction of the target model, the refined pseudo-labels produced by SAM are further postprocessed based on connectivity analysis. Experiments on 3D and 2D datasets indicate that our approach yields superior performance compared to conventional methods. Code is available at https://github.com/xmed-lab/DFG.

arXiv:2504.13077공식 코드 · Papers with Code

Effective Dual-Region Augmentation for Reduced Reliance on Large Amounts of Labeled Data

This paper introduces a novel dual-region augmentation approach designed to reduce reliance on large-scale labeled datasets while improving model robustness and adaptability across diverse computer vision tasks, including source-free domain adaptation (SFDA) and person re-identification (ReID). Our method performs targeted data transformations by applying random noise perturbations to foreground objects and spatially shuffling background patches. This effectively increases the diversity of the training data, improving model robustness and generalization. Evaluations on the PACS dataset for SFDA demonstrate that our augmentation strategy consistently outperforms existing methods, achieving significant accuracy improvements in both single-target and multi-target adaptation settings. By augmenting training data through structured transformations, our method enables model generalization across domains, providing a scalable solution for reducing reliance on manually annotated datasets. Furthermore, experiments on Market-1501 and DukeMTMC-reID datasets validate the effectiveness of our approach for person ReID, surpassing traditional augmentation techniques.

arXiv:2503.20771공식 코드 · Papers with Code

Disentangled Source-Free Personalization for Facial Expression Recognition with Neutral Target Data

Facial Expression Recognition (FER) from videos is a crucial task in various application areas, such as human-computer interaction and health monitoring (e.g., pain, depression, fatigue, and stress). Beyond the challenges of recognizing subtle emotional or health states, the effectiveness of deep FER models is often hindered by the considerable variability of expressions among subjects. Source-free domain adaptation (SFDA) methods are employed to adapt a pre-trained source model using only unlabeled target domain data, thereby avoiding data privacy and storage issues. Typically, SFDA methods adapt to a target domain dataset corresponding to an entire population and assume it includes data from all recognition classes. However, collecting such comprehensive target data can be difficult or even impossible for FER in healthcare applications. In many real-world scenarios, it may be feasible to collect a short neutral control video (displaying only neutral expressions) for target subjects before deployment. These videos can be used to adapt a model to better handle the variability of expressions among subjects. This paper introduces the Disentangled Source-Free Domain Adaptation (DSFDA) method to address the SFDA challenge posed by missing target expression data. DSFDA leverages data from a neutral target control video for end-to-end generation and adaptation of target data with missing non-neutral data. Our method learns to disentangle features related to expressions and identity while generating the missing non-neutral target data, thereby enhancing model accuracy. Additionally, our self-supervision strategy improves model adaptation by reconstructing target images that maintain the same identity and source expression. Experimental results on the challenging BioVid and UNBC-McMaster pain datasets indicate that our DSFDA approach can outperform state-of-the-art adaptation method.

arXiv:2503.08749공식 코드 · Papers with Code

Source-free domain adaptation based on label reliability for cross-domain bearing fault diagnosis

Source-free domain adaptation (SFDA) has been exploited for cross-domain bearing fault diagnosis without access to source data. Current methods select partial target samples with reliable pseudo-labels for model adaptation, which is sub-optimal due to the ignored target samples. We argue that every target sample can contribute to model adaptation, and accordingly propose in this paper a novel SFDA-based approach for bearing fault diagnosis that exploits both reliable and unreliable pseudo-labels. We develop a data-augmentation-based label voting strategy to divide the target samples into reliable and unreliable ones. We propose to explore the underlying relation between feature space and label space by using the reliable pseudo-labels as ground-truth labels, meanwhile, alleviating negative transfer by maximizing the entropy of the unreliable pseudo-labels. The proposed method achieves well-balance between discriminability and diversity by taking advantage of reliable and unreliable pseudo-labels. Extensive experiments are conducted on two bearing fault benchmarks, demonstrating that our approach achieves significant performance improvements against existing SFDA-based bearing fault diagnosis methods. Our code is available at https://github.com/BdLab405/SDALR.

arXiv:2501.03074공식 코드 · Papers with Code

AIF-SFDA: Autonomous Information Filter-driven Source-Free Domain Adaptation for Medical Image Segmentation

Decoupling domain-variant information (DVI) from domain-invariant information (DII) serves as a prominent strategy for mitigating domain shifts in the practical implementation of deep learning algorithms. However, in medical settings, concerns surrounding data collection and privacy often restrict access to both training and test data, hindering the empirical decoupling of information by existing methods. To tackle this issue, we propose an Autonomous Information Filter-driven Source-free Domain Adaptation (AIF-SFDA) algorithm, which leverages a frequency-based learnable information filter to autonomously decouple DVI and DII. Information Bottleneck (IB) and Self-supervision (SS) are incorporated to optimize the learnable frequency filter. The IB governs the information flow within the filter to diminish redundant DVI, while SS preserves DII in alignment with the specific task and image modality. Thus, the autonomous information filter can overcome domain shifts relying solely on target data. A series of experiments covering various medical image modalities and segmentation tasks were conducted to demonstrate the benefits of AIF-SFDA through comparisons with leading algorithms and ablation studies. The code is available at https://github.com/JingHuaMan/AIF-SFDA.

arXiv:2412.14301공식 코드 · Papers with Code

What Has Been Overlooked in Contrastive Source-Free Domain Adaptation: Leveraging Source-Informed Latent Augmentation within Neighborhood Context

Source-free domain adaptation (SFDA) involves adapting a model originally trained using a labeled dataset ({\em source domain}) to perform effectively on an unlabeled dataset ({\em target domain}) without relying on any source data during adaptation. This adaptation is especially crucial when significant disparities in data distributions exist between the two domains and when there are privacy concerns regarding the source model's training data. The absence of access to source data during adaptation makes it challenging to analytically estimate the domain gap. To tackle this issue, various techniques have been proposed, such as unsupervised clustering, contrastive learning, and continual learning. In this paper, we first conduct an extensive theoretical analysis of SFDA based on contrastive learning, primarily because it has demonstrated superior performance compared to other techniques. Motivated by the obtained insights, we then introduce a straightforward yet highly effective latent augmentation method tailored for contrastive SFDA. This augmentation method leverages the dispersion of latent features within the neighborhood of the query sample, guided by the source pre-trained model, to enhance the informativeness of positive keys. Our approach, based on a single InfoNCE-based contrastive loss, outperforms state-of-the-art SFDA methods on widely recognized benchmark datasets.

arXiv:2412.13577공식 코드 · Papers with Code

Bridge then Begin Anew: Generating Target-relevant Intermediate Model for Source-free Visual Emotion Adaptation

Visual emotion recognition (VER), which aims at understanding humans' emotional reactions toward different visual stimuli, has attracted increasing attention. Given the subjective and ambiguous characteristics of emotion, annotating a reliable large-scale dataset is hard. For reducing reliance on data labeling, domain adaptation offers an alternative solution by adapting models trained on labeled source data to unlabeled target data. Conventional domain adaptation methods require access to source data. However, due to privacy concerns, source emotional data may be inaccessible. To address this issue, we propose an unexplored task: source-free domain adaptation (SFDA) for VER, which does not have access to source data during the adaptation process. To achieve this, we propose a novel framework termed Bridge then Begin Anew (BBA), which consists of two steps: domain-bridged model generation (DMG) and target-related model adaptation (TMA). First, the DMG bridges cross-domain gaps by generating an intermediate model, avoiding direct alignment between two VER datasets with significant differences. Then, the TMA begins training the target model anew to fit the target structure, avoiding the influence of source-specific knowledge. Extensive experiments are conducted on six SFDA settings for VER. The results demonstrate the effectiveness of BBA, which achieves remarkable performance gains compared with state-of-the-art SFDA methods and outperforms representative unsupervised domain adaptation approaches.

arXiv:2411.12558공식 코드 · Papers with Code

Recall and Refine: A Simple but Effective Source-free Open-set Domain Adaptation Framework

Open-set Domain Adaptation (OSDA) aims to adapt a model from a labeled source domain to an unlabeled target domain, where novel classes - also referred to as target-private unknown classes - are present. Source-free Open-set Domain Adaptation (SF-OSDA) methods address OSDA without accessing labeled source data, making them particularly relevant under privacy constraints. However, SF-OSDA presents significant challenges due to distribution shifts and the introduction of novel classes. Existing SF-OSDA methods typically rely on thresholding the prediction entropy of a sample to identify it as either a known or unknown class but fail to explicitly learn discriminative features for the target-private unknown classes. We propose Recall and Refine (RRDA), a novel SF-OSDA framework designed to address these limitations by explicitly learning features for target-private unknown classes. RRDA employs a two-step process. First, we enhance the model's capacity to recognize unknown classes by training a target classifier with an additional decision boundary, guided by synthetic samples generated from target domain features. This enables the classifier to effectively separate known and unknown classes. In the second step, we adapt the entire model to the target domain, addressing both domain shifts and improving generalization to unknown classes. Any off-the-shelf source-free domain adaptation method (e.g., SHOT, AaD) can be seamlessly integrated into our framework at this stage. Extensive experiments on three benchmark datasets demonstrate that RRDA significantly outperforms existing SF-OSDA and OSDA methods.

arXiv:2410.16606공식 코드 · Papers with Code

GALA: Graph Diffusion-based Alignment with Jigsaw for Source-free Domain Adaptation

Source-free domain adaptation is a crucial machine learning topic, as it contains numerous applications in the real world, particularly with respect to data privacy. Existing approaches predominantly focus on Euclidean data, such as images and videos, while the exploration of non-Euclidean graph data remains scarce. Recent graph neural network (GNN) approaches can suffer from serious performance decline due to domain shift and label scarcity in source-free adaptation scenarios. In this study, we propose a novel method named Graph Diffusion-based Alignment with Jigsaw (GALA), tailored for source-free graph domain adaptation. To achieve domain alignment, GALA employs a graph diffusion model to reconstruct source-style graphs from target data. Specifically, a score-based graph diffusion model is trained using source graphs to learn the generative source styles. Then, we introduce perturbations to target graphs via a stochastic differential equation instead of sampling from a prior, followed by the reverse process to reconstruct source-style graphs. We feed the source-style graphs into an off-the-shelf GNN and introduce class-specific thresholds with curriculum learning, which can generate accurate and unbiased pseudo-labels for target graphs. Moreover, we develop a simple yet effective graph-mixing strategy named graph jigsaw to combine confident graphs and unconfident graphs, which can enhance generalization capabilities and robustness via consistency learning. Extensive experiments on benchmark datasets validate the effectiveness of GALA.

arXiv:2409.18418공식 코드 · Papers with Code

A3: Active Adversarial Alignment for Source-Free Domain Adaptation

Unsupervised domain adaptation (UDA) aims to transfer knowledge from a labeled source domain to an unlabeled target domain. Recent works have focused on source-free UDA, where only target data is available. This is challenging as models rely on noisy pseudo-labels and struggle with distribution shifts. We propose Active Adversarial Alignment (A3), a novel framework combining self-supervised learning, adversarial training, and active learning for robust source-free UDA. A3 actively samples informative and diverse data using an acquisition function for training. It adapts models via adversarial losses and consistency regularization, aligning distributions without source data access. A3 advances source-free UDA through its synergistic integration of active and adversarial learning for effective domain alignment and noise reduction.

arXiv:2409.16538공식 코드 · Papers with Code

Source-Free Domain Adaptation for YOLO Object Detection

Source-free domain adaptation (SFDA) is a challenging problem in object detection, where a pre-trained source model is adapted to a new target domain without using any source domain data for privacy and efficiency reasons. Most state-of-the-art SFDA methods for object detection have been proposed for Faster-RCNN, a detector that is known to have high computational complexity. This paper focuses on domain adaptation techniques for real-world vision systems, particularly for the YOLO family of single-shot detectors known for their fast baselines and practical applications. Our proposed SFDA method - Source-Free YOLO (SF-YOLO) - relies on a teacher-student framework in which the student receives images with a learned, target domain-specific augmentation, allowing the model to be trained with only unlabeled target data and without requiring feature alignment. A challenge with self-training using a mean-teacher architecture in the absence of labels is the rapid decline of accuracy due to noisy or drifting pseudo-labels. To address this issue, a teacher-to-student communication mechanism is introduced to help stabilize the training and reduce the reliance on annotated target data for model selection. Despite its simplicity, our approach is competitive with state-of-the-art detectors on several challenging benchmark datasets, even sometimes outperforming methods that use source data for adaptation.

arXiv:2409.04409공식 코드 · Papers with Code

Train Till You Drop: Towards Stable and Robust Source-free Unsupervised 3D Domain Adaptation

We tackle the challenging problem of source-free unsupervised domain adaptation (SFUDA) for 3D semantic segmentation. It amounts to performing domain adaptation on an unlabeled target domain without any access to source data; the available information is a model trained to achieve good performance on the source domain. A common issue with existing SFUDA approaches is that performance degrades after some training time, which is a by product of an under-constrained and ill-posed problem. We discuss two strategies to alleviate this issue. First, we propose a sensible way to regularize the learning problem. Second, we introduce a novel criterion based on agreement with a reference model. It is used (1) to stop the training when appropriate and (2) as validator to select hyperparameters without any knowledge on the target domain. Our contributions are easy to implement and readily amenable for all SFUDA methods, ensuring stable improvements over all baselines. We validate our findings on various 3D lidar settings, achieving state-of-the-art performance. The project repository (with code) is: github.com/valeoai/TTYD.

arXiv:2407.16189공식 코드 · Papers with Code

EIANet: A Novel Domain Adaptation Approach to Maximize Class Distinction with Neural Collapse Principles

Source-free domain adaptation (SFDA) aims to transfer knowledge from a labelled source domain to an unlabelled target domain. A major challenge in SFDA is deriving accurate categorical information for the target domain, especially when sample embeddings from different classes appear similar. This issue is particularly pronounced in fine-grained visual categorization tasks, where inter-class differences are subtle. To overcome this challenge, we introduce a novel ETF-Informed Attention Network (EIANet) to separate class prototypes by utilizing attention and neural collapse principles. More specifically, EIANet employs a simplex Equiangular Tight Frame (ETF) classifier in conjunction with an attention mechanism, facilitating the model to focus on discriminative features and ensuring maximum class prototype separation. This innovative approach effectively enlarges the feature difference between different classes in the latent space by locating salient regions, thereby preventing the misclassification of similar but distinct category samples and providing more accurate categorical information to guide the fine-tuning process on the target domain. Experimental results across four SFDA datasets validate EIANet's state-of-the-art performance. Code is available at: https://github.com/zichengpan/EIANet.

arXiv:2407.16497공식 코드 · Papers with Code

Dynamic Retraining-Updating Mean Teacher for Source-Free Object Detection

In object detection, unsupervised domain adaptation (UDA) aims to transfer knowledge from a labeled source domain to an unlabeled target domain. However, UDA's reliance on labeled source data restricts its adaptability in privacy-related scenarios. This study focuses on source-free object detection (SFOD), which adapts a source-trained detector to an unlabeled target domain without using labeled source data. Recent advancements in self-training, particularly with the Mean Teacher (MT) framework, show promise for SFOD deployment. However, the absence of source supervision significantly compromises the stability of these approaches. We identify two primary issues, (1) uncontrollable degradation of the teacher model due to inopportune updates from the student model, and (2) the student model's tendency to replicate errors from incorrect pseudo labels, leading to it being trapped in a local optimum. Both factors contribute to a detrimental circular dependency, resulting in rapid performance degradation in recent self-training frameworks. To tackle these challenges, we propose the Dynamic Retraining-Updating (DRU) mechanism, which actively manages the student training and teacher updating processes to achieve co-evolutionary training. Additionally, we introduce Historical Student Loss to mitigate the influence of incorrect pseudo labels. Our method achieves state-of-the-art performance in the SFOD setting on multiple domain adaptation benchmarks, comparable to or even surpassing advanced UDA methods. The code will be released at https://github.com/lbktrinh/DRU

arXiv:2407.07586공식 코드 · Papers with Code

Simplifying Source-Free Domain Adaptation for Object Detection: Effective Self-Training Strategies and Performance Insights

This paper focuses on source-free domain adaptation for object detection in computer vision. This task is challenging and of great practical interest, due to the cost of obtaining annotated data sets for every new domain. Recent research has proposed various solutions for Source-Free Object Detection (SFOD), most being variations of teacher-student architectures with diverse feature alignment, regularization and pseudo-label selection strategies. Our work investigates simpler approaches and their performance compared to more complex SFOD methods in several adaptation scenarios. We highlight the importance of batch normalization layers in the detector backbone, and show that adapting only the batch statistics is a strong baseline for SFOD. We propose a simple extension of a Mean Teacher with strong-weak augmentation in the source-free setting, Source-Free Unbiased Teacher (SF-UT), and show that it actually outperforms most of the previous SFOD methods. Additionally, we showcase that an even simpler strategy consisting in training on a fixed set of pseudo-labels can achieve similar performance to the more complex teacher-student mutual learning, while being computationally efficient and mitigating the major issue of teacher-student collapse. We conduct experiments on several adaptation tasks using benchmark driving datasets including (Foggy)Cityscapes, Sim10k and KITTI, and achieve a notable improvement of 4.7\% AP50 on Cityscapes$\rightarrow$Foggy-Cityscapes compared with the latest state-of-the-art in SFOD. Source code is available at https://github.com/EPFL-IMOS/simple-SFOD.

arXiv:2407.02893공식 코드 · Papers with Code

An Uncertainty-guided Tiered Self-training Framework for Active Source-free Domain Adaptation in Prostate Segmentation

Deep learning models have exhibited remarkable efficacy in accurately delineating the prostate for diagnosis and treatment of prostate diseases, but challenges persist in achieving robust generalization across different medical centers. Source-free Domain Adaptation (SFDA) is a promising technique to adapt deep segmentation models to address privacy and security concerns while reducing domain shifts between source and target domains. However, recent literature indicates that the performance of SFDA remains far from satisfactory due to unpredictable domain gaps. Annotating a few target domain samples is acceptable, as it can lead to significant performance improvement with a low annotation cost. Nevertheless, due to extremely limited annotation budgets, careful consideration is needed in selecting samples for annotation. Inspired by this, our goal is to develop Active Source-free Domain Adaptation (ASFDA) for medical image segmentation. Specifically, we propose a novel Uncertainty-guided Tiered Self-training (UGTST) framework, consisting of efficient active sample selection via entropy-based primary local peak filtering to aggregate global uncertainty and diversity-aware redundancy filter, coupled with a tiered self-learning strategy, achieves stable domain adaptation. Experimental results on cross-center prostate MRI segmentation datasets revealed that our method yielded marked advancements, with a mere 5% annotation, exhibiting an average Dice score enhancement of 9.78% and 7.58% in two target domains compared with state-of-the-art methods, on par with fully supervised learning. Code is available at:https://github.com/HiLab-git/UGTST

arXiv:2406.01658공식 코드 · Papers with Code

Proxy Denoising for Source-Free Domain Adaptation

Source-Free Domain Adaptation (SFDA) aims to adapt a pre-trained source model to an unlabeled target domain with no access to the source data. Inspired by the success of large Vision-Language (ViL) models in many applications, the latest research has validated ViL's benefit for SFDA by using their predictions as pseudo supervision. However, we observe that ViL's supervision could be noisy and inaccurate at an unknown rate, introducing additional negative effects during adaption. To address this thus-far ignored challenge, we introduce a novel Proxy Denoising (ProDe) approach. The key idea is to leverage the ViL model as a proxy to facilitate the adaptation process towards the latent domain-invariant space. We design a proxy denoising mechanism to correct ViL's predictions, grounded on a proxy confidence theory that models the dynamic effect of proxy's divergence against the domain-invariant space during adaptation. To capitalize on the corrected proxy, we derive a mutual knowledge distilling regularization. Extensive experiments show that ProDe significantly outperforms current state-of-the-art alternatives under the conventional closed set setting and more challenging open set, partial set, generalized SFDA, multi-target, multi-source, and test-time settings. Our code and data are available at https://github.com/tntek/source-free-domain-adaptation.