Harmonization of T1-weighted MR images across different scanners is crucial for ensuring consistency in neuroimaging studies. This study introduces a novel approach to direct image harmonization, moving beyond feature standardization to ensure that extracted features remain inherently reliable for downstream analysis. Our method enables image transfer in two ways: (1) mapping images to a scanner-free space for uniform appearance across all scanners, and (2) transforming images into the domain of a specific scanner used in model training, embedding its unique characteristics. Our approach presents strong generalization capability, even for unseen scanners not included in the training phase. We validated our method using MR images from diverse cohorts, including healthy controls, traveling subjects, and individuals with Alzheimer's disease (AD). The model's effectiveness is tested in multiple applications, such as brain age prediction (R2 = 0.60 \pm 0.05), biomarker extraction, AD classification (Test Accuracy = 0.86 \pm 0.03), and diagnosis prediction (AUC = 0.95). In all cases, our harmonization technique outperforms state-of-the-art methods, showing improvements in both reliability and predictive accuracy. Moreover, our approach eliminates the need for extensive preprocessing steps, such as skull-stripping, which can introduce errors by misclassifying brain and non-brain structures. This makes our method particularly suitable for applications that require full-head analysis, including research on head trauma and cranial deformities. Additionally, our harmonization model does not require retraining for new datasets, allowing smooth integration into various neuroimaging workflows. By ensuring scanner-invariant image quality, our approach provides a robust and efficient solution for improving neuroimaging studies across diverse settings. The code is available at this link.
This paper introduces Bifr\"ost, a novel 3D-aware framework that is built upon diffusion models to perform instruction-based image composition. Previous methods concentrate on image compositing at the 2D level, which fall short in handling complex spatial relationships ($\textit{e.g.}$, occlusion). Bifr\"ost addresses these issues by training MLLM as a 2.5D location predictor and integrating depth maps as an extra condition during the generation process to bridge the gap between 2D and 3D, which enhances spatial comprehension and supports sophisticated spatial interactions. Our method begins by fine-tuning MLLM with a custom counterfactual dataset to predict 2.5D object locations in complex backgrounds from language instructions. Then, the image-compositing model is uniquely designed to process multiple types of input features, enabling it to perform high-fidelity image compositions that consider occlusion, depth blur, and image harmonization. Extensive qualitative and quantitative evaluations demonstrate that Bifr\"ost significantly outperforms existing methods, providing a robust solution for generating realistically composited images in scenarios demanding intricate spatial understanding. This work not only pushes the boundaries of generative image compositing but also reduces reliance on expensive annotated datasets by effectively utilizing existing resources in innovative ways.
We offer a novel approach to image composition, which integrates multiple input images into a single, coherent image. Rather than concentrating on specific use cases such as appearance editing (image harmonization) or semantic editing (semantic image composition), we showcase the potential of utilizing the powerful generative prior inherent in large-scale pre-trained diffusion models to accomplish generic image composition applicable to both scenarios. We observe that the pre-trained diffusion models automatically identify simple copy-paste boundary areas as low-density regions during denoising. Building on this insight, we propose to optimize the composed image towards high-density regions guided by the diffusion prior. In addition, we introduce a novel maskguided loss to further enable flexible semantic image composition. Extensive experiments validate the superiority of our approach in achieving generic zero-shot image composition. Additionally, our approach shows promising potential in various tasks, such as object removal and multiconcept customization.
Painterly image harmonization aims at seamlessly blending disparate visual elements within a single image. However, previous approaches often struggle due to limitations in training data or reliance on additional prompts, leading to inharmonious and content-disrupted output. To surmount these hurdles, we design a Training-and-prompt-Free General Painterly Harmonization method (TF-GPH). TF-GPH incorporates a novel ``Similarity Disentangle Mask'', which disentangles the foreground content and background image by redirecting their attention to corresponding reference images, enhancing the attention mechanism for multi-image inputs. Additionally, we propose a ``Similarity Reweighting'' mechanism to balance harmonization between stylization and content preservation. This mechanism minimizes content disruption by prioritizing the content-similar features within the given background style reference. Finally, we address the deficiencies in existing benchmarks by proposing novel range-based evaluation metrics and a new benchmark to better reflect real-world applications. Extensive experiments demonstrate the efficacy of our method in all benchmarks. More detailed in https://github.com/BlueDyee/TF-GPH.
Image harmonization, which involves adjusting the foreground of a composite image to attain a unified visual consistency with the background, can be conceptualized as an image-to-image translation task. Diffusion models have recently promoted the rapid development of image-to-image translation tasks . However, training diffusion models from scratch is computationally intensive. Fine-tuning pre-trained latent diffusion models entails dealing with the reconstruction error induced by the image compression autoencoder, making it unsuitable for image generation tasks that involve pixel-level evaluation metrics. To deal with these issues, in this paper, we first adapt a pre-trained latent diffusion model to the image harmonization task to generate the harmonious but potentially blurry initial images. Then we implement two strategies: utilizing higher-resolution images during inference and incorporating an additional refinement stage, to further enhance the clarity of the initially harmonized images. Extensive experiments on iHarmony4 datasets demonstrate the superiority of our proposed method. The code and model will be made publicly available at https://github.com/nicecv/DiffHarmony .
In MRI studies, the aggregation of imaging data from multiple acquisition sites enhances sample size but may introduce site-related variabilities that hinder consistency in subsequent analyses. Deep learning methods for image translation have emerged as a solution for harmonizing MR images across sites. In this study, we introduce IGUANe (Image Generation with Unified Adversarial Networks), an original 3D model that leverages the strengths of domain translation and straightforward application of style transfer methods for multicenter brain MR image harmonization. IGUANe extends CycleGAN by integrating an arbitrary number of domains for training through a many-to-one architecture. The framework based on domain pairs enables the implementation of sampling strategies that prevent confusion between site-related and biological variabilities. During inference, the model can be applied to any image, even from an unknown acquisition site, making it a universal generator for harmonization. Trained on a dataset comprising T1-weighted images from 11 different scanners, IGUANe was evaluated on data from unseen sites. The assessments included the transformation of MR images with traveling subjects, the preservation of pairwise distances between MR images within domains, the evolution of volumetric patterns related to age and Alzheimer$'$s disease (AD), and the performance in age regression and patient classification tasks. Comparisons with other harmonization and normalization methods suggest that IGUANe better preserves individual information in MR images and is more suitable for maintaining and reinforcing variabilities related to age and AD. Future studies may further assess IGUANe in other multicenter contexts, either using the same model or retraining it for applications to different image modalities. IGUANe is available at https://github.com/RocaVincent/iguane_harmonization.git.
Painterly image harmonization aims to harmonize a photographic foreground object on the painterly background. Different from previous auto-encoder based harmonization networks, we develop a progressive multi-stage harmonization network, which harmonizes the composite foreground from low-level styles (e.g., color, simple texture) to high-level styles (e.g., complex texture). Our network has better interpretability and harmonization performance. Moreover, we design an early-exit strategy to automatically decide the proper stage to exit, which can skip the unnecessary and even harmful late stages. Extensive experiments on the benchmark dataset demonstrate the effectiveness of our progressive harmonization network.
Given a composite image with photographic object and painterly background, painterly image harmonization targets at stylizing the composite object to be compatible with the background. Despite the competitive performance of existing painterly harmonization works, they did not fully leverage the painterly objects in artistic paintings. In this work, we explore learning from painterly objects for painterly image harmonization. In particular, we learn a mapping from background style and object information to object style based on painterly objects in artistic paintings. With the learnt mapping, we can hallucinate the target style of composite object, which is used to harmonize encoder feature maps to produce the harmonized image. Extensive experiments on the benchmark dataset demonstrate the effectiveness of our proposed method.
Despite significant advancements in network-based image harmonization techniques, there still exists a domain disparity between typical training pairs and real-world composites encountered during inference. Most existing methods are trained to reverse global edits made on segmented image regions, which fail to accurately capture the lighting inconsistencies between the foreground and background found in composited images. In this work, we introduce a self-supervised illumination harmonization approach formulated in the intrinsic image domain. First, we estimate a simple global lighting model from mid-level vision representations to generate a rough shading for the foreground region. A network then refines this inferred shading to generate a harmonious re-shading that aligns with the background scene. In order to match the color appearance of the foreground and background, we utilize ideas from prior harmonization approaches to perform parameterized image edits in the albedo domain. To validate the effectiveness of our approach, we present results from challenging real-world composites and conduct a user study to objectively measure the enhanced realism achieved compared to state-of-the-art harmonization methods.
Image composition targets at synthesizing a realistic composite image from a pair of foreground and background images. Recently, generative composition methods are built on large pretrained diffusion models to generate composite images, considering their great potential in image generation. However, they suffer from lack of controllability on foreground attributes and poor preservation of foreground identity. To address these challenges, we propose a controllable image composition method that unifies four tasks in one diffusion model: image blending, image harmonization, view synthesis, and generative composition. Meanwhile, we design a self-supervised training framework coupled with a tailored pipeline of training data preparation. Moreover, we propose a local enhancement module to enhance the foreground details in the diffusion model, improving the foreground fidelity of composite images. The proposed method is evaluated on both public benchmark and real-world data, which demonstrates that our method can generate more faithful and controllable composite images than existing approaches. The code and model will be available at https://github.com/bcmi/ControlCom-Image-Composition.
Image harmonization is an essential step in image composition that adjusts the appearance of composite foreground to address the inconsistency between foreground and background. Existing methods primarily operate in correlated $RGB$ color space, leading to entangled features and limited representation ability. In contrast, decorrelated color space (e.g., $Lab$) has decorrelated channels that provide disentangled color and illumination statistics. In this paper, we explore image harmonization in dual color spaces, which supplements entangled $RGB$ features with disentangled $L$, $a$, $b$ features to alleviate the workload in harmonization process. The network comprises a $RGB$ harmonization backbone, an $Lab$ encoding module, and an $Lab$ control module. The backbone is a U-Net network translating composite image to harmonized image. Three encoders in $Lab$ encoding module extract three control codes independently from $L$, $a$, $b$ channels, which are used to manipulate the decoder features in harmonization backbone via $Lab$ control module. Our code and model are available at \href{https://github.com/bcmi/DucoNet-Image-Harmonization}{https://github.com/bcmi/DucoNet-Image-Harmonization}.
Painterly image harmonization aims to insert photographic objects into paintings and obtain artistically coherent composite images. Previous methods for this task mainly rely on inference optimization or generative adversarial network, but they are either very time-consuming or struggling at fine control of the foreground objects (e.g., texture and content details). To address these issues, we propose a novel Painterly Harmonization stable Diffusion model (PHDiffusion), which includes a lightweight adaptive encoder and a Dual Encoder Fusion (DEF) module. Specifically, the adaptive encoder and the DEF module first stylize foreground features within each encoder. Then, the stylized foreground features from both encoders are combined to guide the harmonization process. During training, besides the noise loss in diffusion model, we additionally employ content loss and two style losses, i.e., AdaIN style loss and contrastive style loss, aiming to balance the trade-off between style migration and content preservation. Compared with the state-of-the-art models from related fields, our PHDiffusion can stylize the foreground more sufficiently and simultaneously retain finer content. Our code and model are available at https://github.com/bcmi/PHDiffusion-Painterly-Image-Harmonization.
The goal of image harmonization is adjusting the foreground appearance in a composite image to make the whole image harmonious. To construct paired training images, existing datasets adopt different ways to adjust the illumination statistics of foregrounds of real images to produce synthetic composite images. However, different datasets have considerable domain gap and the performances on small-scale datasets are limited by insufficient training data. In this work, we explore learnable augmentation to enrich the illumination diversity of small-scale datasets for better harmonization performance. In particular, our designed SYthetic COmposite Network (SycoNet) takes in a real image with foreground mask and a random vector to learn suitable color transformation, which is applied to the foreground of this real image to produce a synthetic composite image. Comprehensive experiments demonstrate the effectiveness of our proposed learnable augmentation for image harmonization. The code of SycoNet is released at https://github.com/bcmi/SycoNet-Adaptive-Image-Harmonization.
Given a composite image, image harmonization aims to adjust the foreground illumination to be consistent with background. Previous methods have explored transforming foreground features to achieve competitive performance. In this work, we show that using global information to guide foreground feature transformation could achieve significant improvement. Besides, we propose to transfer the foreground-background relation from real images to composite images, which can provide intermediate supervision for the transformed encoder features. Additionally, considering the drawbacks of existing harmonization datasets, we also contribute a ccHarmony dataset which simulates the natural illumination variation. Extensive experiments on iHarmony4 and our contributed dataset demonstrate the superiority of our method. Our ccHarmony dataset is released at https://github.com/bcmi/Image-Harmonization-Dataset-ccHarmony.
We propose a zero-shot approach to image harmonization, aiming to overcome the reliance on large amounts of synthetic composite images in existing methods. These methods, while showing promising results, involve significant training expenses and often struggle with generalization to unseen images. To this end, we introduce a fully modularized framework inspired by human behavior. Leveraging the reasoning capabilities of recent foundation models in language and vision, our approach comprises three main stages. Initially, we employ a pretrained vision-language model (VLM) to generate descriptions for the composite image. Subsequently, these descriptions guide the foreground harmonization direction of a text-to-image generative model (T2I). We refine text embeddings for enhanced representation of imaging conditions and employ self-attention and edge maps for structure preservation. Following each harmonization iteration, an evaluator determines whether to conclude or modify the harmonization direction. The resulting framework, mirroring human behavior, achieves harmonious results without the need for extensive training. We present compelling visual results across diverse scenes and objects, along with a user study validating the effectiveness of our approach.
Accurately segmenting brain lesions in MRI scans is critical for providing patients with prognoses and neurological monitoring. However, the performance of CNN-based segmentation methods is constrained by the limited training set size. Advanced data augmentation is an effective strategy to improve the model's robustness. However, they often introduce intensity disparities between foreground and background areas and boundary artifacts, which weakens the effectiveness of such strategies. In this paper, we propose a foreground harmonization framework (ARHNet) to tackle intensity disparities and make synthetic images look more realistic. In particular, we propose an Adaptive Region Harmonization (ARH) module to dynamically align foreground feature maps to the background with an attention mechanism. We demonstrate the efficacy of our method in improving the segmentation performance using real and synthetic images. Experimental results on the ATLAS 2.0 dataset show that ARHNet outperforms other methods for image harmonization tasks, and boosts the down-stream segmentation performance. Our code is publicly available at https://github.com/King-HAW/ARHNet.
In MRI, images of the same contrast (e.g., T$_1$) from the same subject can exhibit noticeable differences when acquired using different hardware, sequences, or scan parameters. These differences in images create a domain gap that needs to be bridged by a step called image harmonization, to process the images successfully using conventional or deep learning-based image analysis (e.g., segmentation). Several methods, including deep learning-based approaches, have been proposed to achieve image harmonization. However, they often require datasets from multiple domains for deep learning training and may still be unsuccessful when applied to images from unseen domains. To address this limitation, we propose a novel concept called `Blind Harmonization', which utilizes only target domain data for training but still has the capability to harmonize images from unseen domains. For the implementation of blind harmonization, we developed BlindHarmony using an unconditional flow model trained on target domain data. The harmonized image is optimized to have a correlation with the input source domain image while ensuring that the latent vector of the flow model is close to the center of the Gaussian distribution. BlindHarmony was evaluated on both simulated and real datasets and compared to conventional methods. BlindHarmony demonstrated noticeable performance on both datasets, highlighting its potential for future use in clinical settings. The source code is available at: https://github.com/SNU-LIST/BlindHarmony
In this paper, we present a Neural Preset technique to address the limitations of existing color style transfer methods, including visual artifacts, vast memory requirement, and slow style switching speed. Our method is based on two core designs. First, we propose Deterministic Neural Color Mapping (DNCM) to consistently operate on each pixel via an image-adaptive color mapping matrix, avoiding artifacts and supporting high-resolution inputs with a small memory footprint. Second, we develop a two-stage pipeline by dividing the task into color normalization and stylization, which allows efficient style switching by extracting color styles as presets and reusing them on normalized input images. Due to the unavailability of pairwise datasets, we describe how to train Neural Preset via a self-supervised strategy. Various advantages of Neural Preset over existing methods are demonstrated through comprehensive evaluations. Notably, Neural Preset enables stable 4K color style transfer in real-time without artifacts. Besides, we show that our trained model can naturally support multiple applications without fine-tuning, including low-light image enhancement, underwater image correction, image dehazing, and image harmonization. Project page with demos: https://zhkkke.github.io/NeuralPreset .
High-resolution (HR) image harmonization is of great significance in real-world applications such as image synthesis and image editing. However, due to the high memory costs, existing dense pixel-to-pixel harmonization methods are mainly focusing on processing low-resolution (LR) images. Some recent works resort to combining with color-to-color transformations but are either limited to certain resolutions or heavily depend on hand-crafted image filters. In this work, we explore leveraging the implicit neural representation (INR) and propose a novel image Harmonization method based on Implicit neural Networks (HINet), which to the best of our knowledge, is the first dense pixel-to-pixel method applicable to HR images without any hand-crafted filter design. Inspired by the Retinex theory, we decouple the MLPs into two parts to respectively capture the content and environment of composite images. A Low-Resolution Image Prior (LRIP) network is designed to alleviate the Boundary Inconsistency problem, and we also propose new designs for the training and inference process. Extensive experiments have demonstrated the effectiveness of our method compared with state-of-the-art methods. Furthermore, some interesting and practical applications of the proposed method are explored. Our code is available at https://github.com/WindVChen/INR-Harmonization.
Image harmonization aims to produce visually harmonious composite images by adjusting the foreground appearance to be compatible with the background. When the composite image has photographic foreground and painterly background, the task is called painterly image harmonization. There are only few works on this task, which are either time-consuming or weak in generating well-harmonized results. In this work, we propose a novel painterly harmonization network consisting of a dual-domain generator and a dual-domain discriminator, which harmonizes the composite image in both spatial domain and frequency domain. The dual-domain generator performs harmonization by using AdaIN modules in the spatial domain and our proposed ResFFT modules in the frequency domain. The dual-domain discriminator attempts to distinguish the inharmonious patches based on the spatial feature and frequency feature of each patch, which can enhance the ability of generator in an adversarial manner. Extensive experiments on the benchmark dataset show the effectiveness of our method. Our code and model are available at https://github.com/bcmi/PHDNet-Painterly-Image-Harmonization.