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arXiv:2505.16399공식 코드 · Papers with Code

Sketchy Bounding-box Supervision for 3D Instance Segmentation

Bounding box supervision has gained considerable attention in weakly supervised 3D instance segmentation. While this approach alleviates the need for extensive point-level annotations, obtaining accurate bounding boxes in practical applications remains challenging. To this end, we explore the inaccurate bounding box, named sketchy bounding box, which is imitated through perturbing ground truth bounding box by adding scaling, translation, and rotation. In this paper, we propose Sketchy-3DIS, a novel weakly 3D instance segmentation framework, which jointly learns pseudo labeler and segmentator to improve the performance under the sketchy bounding-box supervisions. Specifically, we first propose an adaptive box-to-point pseudo labeler that adaptively learns to assign points located in the overlapped parts between two sketchy bounding boxes to the correct instance, resulting in compact and pure pseudo instance labels. Then, we present a coarse-to-fine instance segmentator that first predicts coarse instances from the entire point cloud and then learns fine instances based on the region of coarse instances. Finally, by using the pseudo instance labels to supervise the instance segmentator, we can gradually generate high-quality instances through joint training. Extensive experiments show that our method achieves state-of-the-art performance on both the ScanNetV2 and S3DIS benchmarks, and even outperforms several fully supervised methods using sketchy bounding boxes. Code is available at https://github.com/dengq7/Sketchy-3DIS.

arXiv:2502.17429공식 코드 · Papers with Code

CLIMB-3D: Continual Learning for Imbalanced 3D Instance Segmentation

While 3D instance segmentation (3DIS) has advanced significantly, existing methods typically assume that all object classes are known in advance and are uniformly distributed. However, this assumption is unrealistic in dynamic, real-world environments where new classes emerge gradually and exhibit natural imbalance. Although some approaches have addressed class emergence, they often overlook class imbalance, resulting in suboptimal performance -- particularly on rare categories. To tackle this challenge, we propose CLIMB-3D, a unified framework for \textbf{CL}ass-incremental \textbf{Imb}alance-aware \textbf{3D}IS. Building upon established exemplar replay (ER) strategies, we show that ER alone is insufficient to achieve robust performance under constrained memory conditions. To mitigate this, we introduce a novel pseudo-label generator (PLG) that extends supervision to previously learned categories by leveraging predictions from a frozen prior model. Despite its promise, PLG tends to bias towards frequent classes. Therefore, we propose a class-balanced re-weighting (CBR) scheme, that estimates object frequencies from pseudo-labels and dynamically adjusts training bias -- without requiring access to past data. We design and evaluate three incremental scenarios for 3DIS on the challenging ScanNet200 dataset, and additionally on semantic segmentation on ScanNetV2. Our approach achieves state-of-the-art results, surpassing prior work by up to 16.76\% mAP for instance segmentation and approximately 30\% mIoU for semantic segmentation, demonstrating strong generalization across both frequent and rare classes.

arXiv:2411.07799공식 코드 · Papers with Code

Horticultural Temporal Fruit Monitoring via 3D Instance Segmentation and Re-Identification using Point Clouds

Robotic fruit monitoring is a key step toward automated agricultural production systems. Robots can significantly enhance plant and temporal fruit monitoring by providing precise, high-throughput assessments that overcome the limitations of traditional manual methods. Fruit monitoring is a challenging task due to the significant variation in size, shape, orientation, and occlusion of fruits. Also, fruits may be harvested or newly grown between recording sessions. Most methods are 2D image-based and they lack the 3D structure, depth, and spatial information, which represent key aspects of fruit monitoring. 3D colored point clouds, instead, can offer this information but they introduce challenges such as their sparsity and irregularity. In this paper, we present a novel approach for temporal fruit monitoring that addresses point clouds collected in a greenhouse over time. Our method segments fruits using a learning-based instance segmentation approach directly on the point cloud. Each segmented fruit is processed by a 3D sparse convolutional neural network to extract descriptors, which are used in an attention-based matching network to associate fruits with their instances from previous data collections. Experimental results on a real dataset of strawberries demonstrate that our approach outperforms other methods for fruits re-identification over time, allowing for precise temporal fruit monitoring in real and complex scenarios.

arXiv:2411.03819공식 코드 · Papers with Code

SA3DIP: Segment Any 3D Instance with Potential 3D Priors

The proliferation of 2D foundation models has sparked research into adapting them for open-world 3D instance segmentation. Recent methods introduce a paradigm that leverages superpoints as geometric primitives and incorporates 2D multi-view masks from Segment Anything model (SAM) as merging guidance, achieving outstanding zero-shot instance segmentation results. However, the limited use of 3D priors restricts the segmentation performance. Previous methods calculate the 3D superpoints solely based on estimated normal from spatial coordinates, resulting in under-segmentation for instances with similar geometry. Besides, the heavy reliance on SAM and hand-crafted algorithms in 2D space suffers from over-segmentation due to SAM's inherent part-level segmentation tendency. To address these issues, we propose SA3DIP, a novel method for Segmenting Any 3D Instances via exploiting potential 3D Priors. Specifically, on one hand, we generate complementary 3D primitives based on both geometric and textural priors, which reduces the initial errors that accumulate in subsequent procedures. On the other hand, we introduce supplemental constraints from the 3D space by using a 3D detector to guide a further merging process. Furthermore, we notice a considerable portion of low-quality ground truth annotations in ScanNetV2 benchmark, which affect the fair evaluations. Thus, we present ScanNetV2-INS with complete ground truth labels and supplement additional instances for 3D class-agnostic instance segmentation. Experimental evaluations on various 2D-3D datasets demonstrate the effectiveness and robustness of our approach. Our code and proposed ScanNetV2-INS dataset are available HERE.

arXiv:2407.11564공식 코드 · Papers with Code

SGIFormer: Semantic-guided and Geometric-enhanced Interleaving Transformer for 3D Instance Segmentation

In recent years, transformer-based models have exhibited considerable potential in point cloud instance segmentation. Despite the promising performance achieved by existing methods, they encounter challenges such as instance query initialization problems and excessive reliance on stacked layers, rendering them incompatible with large-scale 3D scenes. This paper introduces a novel method, named SGIFormer, for 3D instance segmentation, which is composed of the Semantic-guided Mix Query (SMQ) initialization and the Geometric-enhanced Interleaving Transformer (GIT) decoder. Specifically, the principle of our SMQ initialization scheme is to leverage the predicted voxel-wise semantic information to implicitly generate the scene-aware query, yielding adequate scene prior and compensating for the learnable query set. Subsequently, we feed the formed overall query into our GIT decoder to alternately refine instance query and global scene features for further capturing fine-grained information and reducing complex design intricacies simultaneously. To emphasize geometric property, we consider bias estimation as an auxiliary task and progressively integrate shifted point coordinates embedding to reinforce instance localization. SGIFormer attains state-of-the-art performance on ScanNet V2, ScanNet200 datasets, and the challenging high-fidelity ScanNet++ benchmark, striking a balance between accuracy and efficiency. The code, weights, and demo videos are publicly available at https://rayyoh.github.io/sgiformer.

arXiv:2407.10084공식 코드 · Papers with Code

Part2Object: Hierarchical Unsupervised 3D Instance Segmentation

Unsupervised 3D instance segmentation aims to segment objects from a 3D point cloud without any annotations. Existing methods face the challenge of either too loose or too tight clustering, leading to under-segmentation or over-segmentation. To address this issue, we propose Part2Object, hierarchical clustering with object guidance. Part2Object employs multi-layer clustering from points to object parts and objects, allowing objects to manifest at any layer. Additionally, it extracts and utilizes 3D objectness priors from temporally consecutive 2D RGB frames to guide the clustering process. Moreover, we propose Hi-Mask3D to support hierarchical 3D object part and instance segmentation. By training Hi-Mask3D on the objects and object parts extracted from Part2Object, we achieve consistent and superior performance compared to state-of-the-art models in various settings, including unsupervised instance segmentation, data-efficient fine-tuning, and cross-dataset generalization. Code is release at https://github.com/ChengShiest/Part2Object

arXiv:2406.16776공식 코드 · Papers with Code

Instance Consistency Regularization for Semi-Supervised 3D Instance Segmentation

Large-scale datasets with point-wise semantic and instance labels are crucial to 3D instance segmentation but also expensive. To leverage unlabeled data, previous semi-supervised 3D instance segmentation approaches have explored self-training frameworks, which rely on high-quality pseudo labels for consistency regularization. They intuitively utilize both instance and semantic pseudo labels in a joint learning manner. However, semantic pseudo labels contain numerous noise derived from the imbalanced category distribution and natural confusion of similar but distinct categories, which leads to severe collapses in self-training. Motivated by the observation that 3D instances are non-overlapping and spatially separable, we ask whether we can solely rely on instance consistency regularization for improved semi-supervised segmentation. To this end, we propose a novel self-training network InsTeacher3D to explore and exploit pure instance knowledge from unlabeled data. We first build a parallel base 3D instance segmentation model DKNet, which distinguishes each instance from the others via discriminative instance kernels without reliance on semantic segmentation. Based on DKNet, we further design a novel instance consistency regularization framework to generate and leverage high-quality instance pseudo labels. Experimental results on multiple large-scale datasets show that the InsTeacher3D significantly outperforms prior state-of-the-art semi-supervised approaches. Code is available: https://github.com/W1zheng/InsTeacher3D.

arXiv:2406.02548공식 코드 · Papers with Code

Open-YOLO 3D: Towards Fast and Accurate Open-Vocabulary 3D Instance Segmentation

Recent works on open-vocabulary 3D instance segmentation show strong promise, but at the cost of slow inference speed and high computation requirements. This high computation cost is typically due to their heavy reliance on 3D clip features, which require computationally expensive 2D foundation models like Segment Anything (SAM) and CLIP for multi-view aggregation into 3D. As a consequence, this hampers their applicability in many real-world applications that require both fast and accurate predictions. To this end, we propose a fast yet accurate open-vocabulary 3D instance segmentation approach, named Open-YOLO 3D, that effectively leverages only 2D object detection from multi-view RGB images for open-vocabulary 3D instance segmentation. We address this task by generating class-agnostic 3D masks for objects in the scene and associating them with text prompts. We observe that the projection of class-agnostic 3D point cloud instances already holds instance information; thus, using SAM might only result in redundancy that unnecessarily increases the inference time. We empirically find that a better performance of matching text prompts to 3D masks can be achieved in a faster fashion with a 2D object detector. We validate our Open-YOLO 3D on two benchmarks, ScanNet200 and Replica, under two scenarios: (i) with ground truth masks, where labels are required for given object proposals, and (ii) with class-agnostic 3D proposals generated from a 3D proposal network. Our Open-YOLO 3D achieves state-of-the-art performance on both datasets while obtaining up to $\sim$16$\times$ speedup compared to the best existing method in literature. On ScanNet200 val. set, our Open-YOLO 3D achieves mean average precision (mAP) of 24.7\% while operating at 22 seconds per scene. Code and model are available at github.com/aminebdj/OpenYOLO3D.

arXiv:2403.16318공식 코드 · Papers with Code

AutoInst: Automatic Instance-Based Segmentation of LiDAR 3D Scans

Recently, progress in acquisition equipment such as LiDAR sensors has enabled sensing increasingly spacious outdoor 3D environments. Making sense of such 3D acquisitions requires fine-grained scene understanding, such as constructing instance-based 3D scene segmentations. Commonly, a neural network is trained for this task; however, this requires access to a large, densely annotated dataset, which is widely known to be challenging to obtain. To address this issue, in this work we propose to predict instance segmentations for 3D scenes in an unsupervised way, without relying on ground-truth annotations. To this end, we construct a learning framework consisting of two components: (1) a pseudo-annotation scheme for generating initial unsupervised pseudo-labels; and (2) a self-training algorithm for instance segmentation to fit robust, accurate instances from initial noisy proposals. To enable generating 3D instance mask proposals, we construct a weighted proxy-graph by connecting 3D points with edges integrating multi-modal image- and point-based self-supervised features, and perform graph-cuts to isolate individual pseudo-instances. We then build on a state-of-the-art point-based architecture and train a 3D instance segmentation model, resulting in significant refinement of initial proposals. To scale to arbitrary complexity 3D scenes, we design our algorithm to operate on local 3D point chunks and construct a merging step to generate scene-level instance segmentations. Experiments on the challenging SemanticKITTI benchmark demonstrate the potential of our approach, where it attains 13.3% higher Average Precision and 9.1% higher F1 score compared to the best-performing baseline. The code will be made publicly available at https://github.com/artonson/autoinst.

arXiv:2403.15019공식 코드 · Papers with Code

BSNet: Box-Supervised Simulation-assisted Mean Teacher for 3D Instance Segmentation

3D instance segmentation (3DIS) is a crucial task, but point-level annotations are tedious in fully supervised settings. Thus, using bounding boxes (bboxes) as annotations has shown great potential. The current mainstream approach is a two-step process, involving the generation of pseudo-labels from box annotations and the training of a 3DIS network with the pseudo-labels. However, due to the presence of intersections among bboxes, not every point has a determined instance label, especially in overlapping areas. To generate higher quality pseudo-labels and achieve more precise weakly supervised 3DIS results, we propose the Box-Supervised Simulation-assisted Mean Teacher for 3D Instance Segmentation (BSNet), which devises a novel pseudo-labeler called Simulation-assisted Transformer. The labeler consists of two main components. The first is Simulation-assisted Mean Teacher, which introduces Mean Teacher for the first time in this task and constructs simulated samples to assist the labeler in acquiring prior knowledge about overlapping areas. To better model local-global structure, we also propose Local-Global Aware Attention as the decoder for teacher and student labelers. Extensive experiments conducted on the ScanNetV2 and S3DIS datasets verify the superiority of our designs. Code is available at \href{https://github.com/peoplelu/BSNet}{https://github.com/peoplelu/BSNet}.

arXiv:2401.03298공식 코드 · Papers with Code

ENSTRECT: A Stage-based Approach to 2.5D Structural Damage Detection

To effectively assess structural damage, it is essential to localize the instances of damage in the physical world of a civil structure. ENSTRECT is a stage-based approach designed to accomplish 2.5D structural damage detection. The method requires an image collection, the relative orientation, and a point cloud. Using these inputs, surface damages are segmented at the image level and then mapped into the point cloud space, resulting in a segmented point cloud. To enable further quantitative analyses, the segmented point cloud is transformed into measurable damage instances: cracks are extracted by contracting the clustered point cloud into a corresponding medial axis. For areal damages, such as spalling and corrosion, a procedure is proposed to compute the bounding polygon based on PCA and alpha shapes. With a localization tolerance of 4cm, ENSTRECT can achieve IoUs of over 90% for cracks, 82% for corrosion, and 41% for spalling. Detection at the instance level yields an AP50 of about 45% (cracks, spalling) and 56% (corrosion).

arXiv:2401.02416공식 코드 · Papers with Code

ODIN: A Single Model for 2D and 3D Segmentation

State-of-the-art models on contemporary 3D segmentation benchmarks like ScanNet consume and label dataset-provided 3D point clouds, obtained through post processing of sensed multiview RGB-D images. They are typically trained in-domain, forego large-scale 2D pre-training and outperform alternatives that featurize the posed RGB-D multiview images instead. The gap in performance between methods that consume posed images versus post-processed 3D point clouds has fueled the belief that 2D and 3D perception require distinct model architectures. In this paper, we challenge this view and propose ODIN (Omni-Dimensional INstance segmentation), a model that can segment and label both 2D RGB images and 3D point clouds, using a transformer architecture that alternates between 2D within-view and 3D cross-view information fusion. Our model differentiates 2D and 3D feature operations through the positional encodings of the tokens involved, which capture pixel coordinates for 2D patch tokens and 3D coordinates for 3D feature tokens. ODIN achieves state-of-the-art performance on ScanNet200, Matterport3D and AI2THOR 3D instance segmentation benchmarks, and competitive performance on ScanNet, S3DIS and COCO. It outperforms all previous works by a wide margin when the sensed 3D point cloud is used in place of the point cloud sampled from 3D mesh. When used as the 3D perception engine in an instructable embodied agent architecture, it sets a new state-of-the-art on the TEACh action-from-dialogue benchmark. Our code and checkpoints can be found at the project website (https://odin-seg.github.io).

arXiv:2312.11269공식 코드 · Papers with Code

Spherical Mask: Coarse-to-Fine 3D Point Cloud Instance Segmentation with Spherical Representation

Coarse-to-fine 3D instance segmentation methods show weak performances compared to recent Grouping-based, Kernel-based and Transformer-based methods. We argue that this is due to two limitations: 1) Instance size overestimation by axis-aligned bounding box(AABB) 2) False negative error accumulation from inaccurate box to the refinement phase. In this work, we introduce Spherical Mask, a novel coarse-to-fine approach based on spherical representation, overcoming those two limitations with several benefits. Specifically, our coarse detection estimates each instance with a 3D polygon using a center and radial distance predictions, which avoids excessive size estimation of AABB. To cut the error propagation in the existing coarse-to-fine approaches, we virtually migrate points based on the polygon, allowing all foreground points, including false negatives, to be refined. During inference, the proposal and point migration modules run in parallel and are assembled to form binary masks of instances. We also introduce two margin-based losses for the point migration to enforce corrections for the false positives/negatives and cohesion of foreground points, significantly improving the performance. Experimental results from three datasets, such as ScanNetV2, S3DIS, and STPLS3D, show that our proposed method outperforms existing works, demonstrating the effectiveness of the new instance representation with spherical coordinates. The code is available at: https://github.com/yunshin/SphericalMask

arXiv:2312.10671공식 코드 · Papers with Code

Open3DIS: Open-Vocabulary 3D Instance Segmentation with 2D Mask Guidance

We introduce Open3DIS, a novel solution designed to tackle the problem of Open-Vocabulary Instance Segmentation within 3D scenes. Objects within 3D environments exhibit diverse shapes, scales, and colors, making precise instance-level identification a challenging task. Recent advancements in Open-Vocabulary scene understanding have made significant strides in this area by employing class-agnostic 3D instance proposal networks for object localization and learning queryable features for each 3D mask. While these methods produce high-quality instance proposals, they struggle with identifying small-scale and geometrically ambiguous objects. The key idea of our method is a new module that aggregates 2D instance masks across frames and maps them to geometrically coherent point cloud regions as high-quality object proposals addressing the above limitations. These are then combined with 3D class-agnostic instance proposals to include a wide range of objects in the real world. To validate our approach, we conducted experiments on three prominent datasets, including ScanNet200, S3DIS, and Replica, demonstrating significant performance gains in segmenting objects with diverse categories over the state-of-the-art approaches.

arXiv:2312.06988공식 코드 · Papers with Code

MWSIS: Multimodal Weakly Supervised Instance Segmentation with 2D Box Annotations for Autonomous Driving

Instance segmentation is a fundamental research in computer vision, especially in autonomous driving. However, manual mask annotation for instance segmentation is quite time-consuming and costly. To address this problem, some prior works attempt to apply weakly supervised manner by exploring 2D or 3D boxes. However, no one has ever successfully segmented 2D and 3D instances simultaneously by only using 2D box annotations, which could further reduce the annotation cost by an order of magnitude. Thus, we propose a novel framework called Multimodal Weakly Supervised Instance Segmentation (MWSIS), which incorporates various fine-grained label generation and correction modules for both 2D and 3D modalities to improve the quality of pseudo labels, along with a new multimodal cross-supervision approach, named Consistency Sparse Cross-modal Supervision (CSCS), to reduce the inconsistency of multimodal predictions by response distillation. Particularly, transferring the 3D backbone to downstream tasks not only improves the performance of the 3D detectors, but also outperforms fully supervised instance segmentation with only 5% fully supervised annotations. On the Waymo dataset, the proposed framework demonstrates significant improvements over the baseline, especially achieving 2.59% mAP and 12.75% mAP increases for 2D and 3D instance segmentation tasks, respectively. The code is available at https://github.com/jiangxb98/mwsis-plugin.

arXiv:2312.03015공식 코드 · Papers with Code

PartSLIP++: Enhancing Low-Shot 3D Part Segmentation via Multi-View Instance Segmentation and Maximum Likelihood Estimation

Open-world 3D part segmentation is pivotal in diverse applications such as robotics and AR/VR. Traditional supervised methods often grapple with limited 3D data availability and struggle to generalize to unseen object categories. PartSLIP, a recent advancement, has made significant strides in zero- and few-shot 3D part segmentation. This is achieved by harnessing the capabilities of the 2D open-vocabulary detection module, GLIP, and introducing a heuristic method for converting and lifting multi-view 2D bounding box predictions into 3D segmentation masks. In this paper, we introduce PartSLIP++, an enhanced version designed to overcome the limitations of its predecessor. Our approach incorporates two major improvements. First, we utilize a pre-trained 2D segmentation model, SAM, to produce pixel-wise 2D segmentations, yielding more precise and accurate annotations than the 2D bounding boxes used in PartSLIP. Second, PartSLIP++ replaces the heuristic 3D conversion process with an innovative modified Expectation-Maximization algorithm. This algorithm conceptualizes 3D instance segmentation as unobserved latent variables, and then iteratively refines them through an alternating process of 2D-3D matching and optimization with gradient descent. Through extensive evaluations, we show that PartSLIP++ demonstrates better performance over PartSLIP in both low-shot 3D semantic and instance-based object part segmentation tasks. Code released at https://github.com/zyc00/PartSLIP2.

arXiv:2309.14338공식 코드 · Papers with Code

3D Indoor Instance Segmentation in an Open-World

Existing 3D instance segmentation methods typically assume that all semantic classes to be segmented would be available during training and only seen categories are segmented at inference. We argue that such a closed-world assumption is restrictive and explore for the first time 3D indoor instance segmentation in an open-world setting, where the model is allowed to distinguish a set of known classes as well as identify an unknown object as unknown and then later incrementally learning the semantic category of the unknown when the corresponding category labels are available. To this end, we introduce an open-world 3D indoor instance segmentation method, where an auto-labeling scheme is employed to produce pseudo-labels during training and induce separation to separate known and unknown category labels. We further improve the pseudo-labels quality at inference by adjusting the unknown class probability based on the objectness score distribution. We also introduce carefully curated open-world splits leveraging realistic scenarios based on inherent object distribution, region-based indoor scene exploration and randomness aspect of open-world classes. Extensive experiments reveal the efficacy of the proposed contributions leading to promising open-world 3D instance segmentation performance.

arXiv:2309.01692공식 코드 · Papers with Code

Mask-Attention-Free Transformer for 3D Instance Segmentation

Recently, transformer-based methods have dominated 3D instance segmentation, where mask attention is commonly involved. Specifically, object queries are guided by the initial instance masks in the first cross-attention, and then iteratively refine themselves in a similar manner. However, we observe that the mask-attention pipeline usually leads to slow convergence due to low-recall initial instance masks. Therefore, we abandon the mask attention design and resort to an auxiliary center regression task instead. Through center regression, we effectively overcome the low-recall issue and perform cross-attention by imposing positional prior. To reach this goal, we develop a series of position-aware designs. First, we learn a spatial distribution of 3D locations as the initial position queries. They spread over the 3D space densely, and thus can easily capture the objects in a scene with a high recall. Moreover, we present relative position encoding for the cross-attention and iterative refinement for more accurate position queries. Experiments show that our approach converges 4x faster than existing work, sets a new state of the art on ScanNetv2 3D instance segmentation benchmark, and also demonstrates superior performance across various datasets. Code and models are available at https://github.com/dvlab-research/Mask-Attention-Free-Transformer.

arXiv:2307.13251공식 코드 · Papers with Code

GaPro: Box-Supervised 3D Point Cloud Instance Segmentation Using Gaussian Processes as Pseudo Labelers

Instance segmentation on 3D point clouds (3DIS) is a longstanding challenge in computer vision, where state-of-the-art methods are mainly based on full supervision. As annotating ground truth dense instance masks is tedious and expensive, solving 3DIS with weak supervision has become more practical. In this paper, we propose GaPro, a new instance segmentation for 3D point clouds using axis-aligned 3D bounding box supervision. Our two-step approach involves generating pseudo labels from box annotations and training a 3DIS network with the resulting labels. Additionally, we employ the self-training strategy to improve the performance of our method further. We devise an effective Gaussian Process to generate pseudo instance masks from the bounding boxes and resolve ambiguities when they overlap, resulting in pseudo instance masks with their uncertainty values. Our experiments show that GaPro outperforms previous weakly supervised 3D instance segmentation methods and has competitive performance compared to state-of-the-art fully supervised ones. Furthermore, we demonstrate the robustness of our approach, where we can adapt various state-of-the-art fully supervised methods to the weak supervision task by using our pseudo labels for training. The source code and trained models are available at https://github.com/VinAIResearch/GaPro.

arXiv:2307.07044공식 코드 · Papers with Code

AnyStar: Domain randomized universal star-convex 3D instance segmentation

Star-convex shapes arise across bio-microscopy and radiology in the form of nuclei, nodules, metastases, and other units. Existing instance segmentation networks for such structures train on densely labeled instances for each dataset, which requires substantial and often impractical manual annotation effort. Further, significant reengineering or finetuning is needed when presented with new datasets and imaging modalities due to changes in contrast, shape, orientation, resolution, and density. We present AnyStar, a domain-randomized generative model that simulates synthetic training data of blob-like objects with randomized appearance, environments, and imaging physics to train general-purpose star-convex instance segmentation networks. As a result, networks trained using our generative model do not require annotated images from unseen datasets. A single network trained on our synthesized data accurately 3D segments C. elegans and P. dumerilii nuclei in fluorescence microscopy, mouse cortical nuclei in micro-CT, zebrafish brain nuclei in EM, and placental cotyledons in human fetal MRI, all without any retraining, finetuning, transfer learning, or domain adaptation. Code is available at https://github.com/neel-dey/AnyStar.