We consider the effect of introducing a curriculum of targets when training Boolean models on supervised Multi Label Classification (MLC) problems. In particular, we consider how to order targets in the absence of prior knowledge, and how such a curriculum may be enforced when using meta-heuristics to train discrete non-linear models. We show that hierarchical dependencies between targets can be exploited by enforcing an appropriate curriculum using hierarchical loss functions. On several multi output circuit-inference problems with known target difficulties, Feedforward Boolean Networks (FBNs) trained with such a loss function achieve significantly lower out-of-sample error, up to $10\%$ in some cases. This improvement increases as the loss places more emphasis on target order and is strongly correlated with an easy-to-hard curricula. We also demonstrate the same improvements on three real-world models and two Gene Regulatory Network (GRN) inference problems. We posit a simple a-priori method for identifying an appropriate target order and estimating the strength of target relationships in Boolean MLCs. These methods use intrinsic dimension as a proxy for target difficulty, which is estimated using optimal solutions to a combinatorial optimisation problem known as the Minimum-Feature-Set (minFS) problem. We also demonstrate that the same generalisation gains can be achieved without providing any knowledge of target difficulty.
Manually labeling documents is tedious and expensive, but it is essential for training a traditional text classifier. In recent years, a few dataless text classification techniques have been proposed to address this problem. However, existing works mainly center on single-label classification problems, that is, each document is restricted to belonging to a single category. In this paper, we propose a novel Seed-guided Multi-label Topic Model, named SMTM. With a few seed words relevant to each category, SMTM conducts multi-label classification for a collection of documents without any labeled document. In SMTM, each category is associated with a single category-topic which covers the meaning of the category. To accommodate with multi-labeled documents, we explicitly model the category sparsity in SMTM by using spike and slab prior and weak smoothing prior. That is, without using any threshold tuning, SMTM automatically selects the relevant categories for each document. To incorporate the supervision of the seed words, we propose a seed-guided biased GPU (i.e., generalized Polya urn) sampling procedure to guide the topic inference of SMTM. Experiments on two public datasets show that SMTM achieves better classification accuracy than state-of-the-art alternatives and even outperforms supervised solutions in some scenarios.
In the context of the Electronic Health Record, automated diagnosis coding of patient notes is a useful task, but a challenging one due to the large number of codes and the length of patient notes. We investigate four models for assigning multiple ICD codes to discharge summaries taken from both MIMIC II and III. We present Hierarchical Attention-GRU (HA-GRU), a hierarchical approach to tag a document by identifying the sentences relevant for each label. HA-GRU achieves state-of-the art results. Furthermore, the learned sentence-level attention layer highlights the model decision process, allows easier error analysis, and suggests future directions for improvement.
Recent work has shown that convolutional networks can be substantially deeper, more accurate, and efficient to train if they contain shorter connections between layers close to the input and those close to the output. In this paper, we embrace this observation and introduce the Dense Convolutional Network (DenseNet), which connects each layer to every other layer in a feed-forward fashion. Whereas traditional convolutional networks with L layers have L connections - one between each layer and its subsequent layer - our network has L(L+1)/2 direct connections. For each layer, the feature-maps of all preceding layers are used as inputs, and its own feature-maps are used as inputs into all subsequent layers. DenseNets have several compelling advantages: they alleviate the vanishing-gradient problem, strengthen feature propagation, encourage feature reuse, and substantially reduce the number of parameters. We evaluate our proposed architecture on four highly competitive object recognition benchmark tasks (CIFAR-10, CIFAR-100, SVHN, and ImageNet). DenseNets obtain significant improvements over the state-of-the-art on most of them, whilst requiring less computation to achieve high performance. Code and pre-trained models are available at https://github.com/liuzhuang13/DenseNet .
The field of medical diagnostics contains a wealth of challenges which closely resemble classical machine learning problems; practical constraints, however, complicate the translation of these endpoints naively into classical architectures. Many tasks in radiology, for example, are largely problems of multi-label classification wherein medical images are interpreted to indicate multiple present or suspected pathologies. Clinical settings drive the necessity for high accuracy simultaneously across a multitude of pathological outcomes and greatly limit the utility of tools which consider only a subset. This issue is exacerbated by a general scarcity of training data and maximizes the need to extract clinically relevant features from available samples -- ideally without the use of pre-trained models which may carry forward undesirable biases from tangentially related tasks. We present and evaluate a partial solution to these constraints in using LSTMs to leverage interdependencies among target labels in predicting 14 pathologic patterns from chest x-rays and establish state of the art results on the largest publicly available chest x-ray dataset from the NIH without pre-training. Furthermore, we propose and discuss alternative evaluation metrics and their relevance in clinical practice.
Multi-label classification (MLC) is an important class of machine learning problems that come with a wide spectrum of applications, each demanding a possibly different evaluation criterion. When solving the MLC problems, we generally expect the learning algorithm to take the hidden correlation of the labels into account to improve the prediction performance. Extracting the hidden correlation is generally a challenging task. In this work, we propose a novel deep learning framework to better extract the hidden correlation with the help of the memory structure within recurrent neural networks. The memory stores the temporary guesses on the labels and effectively allows the framework to rethink about the goodness and correlation of the guesses before making the final prediction. Furthermore, the rethinking process makes it easy to adapt to different evaluation criteria to match real-world application needs. In particular, the framework can be trained in an end-to-end style with respect to any given MLC evaluation criteria. The end-to-end design can be seamlessly combined with other deep learning techniques to conquer challenging MLC problems like image tagging. Experimental results across many real-world data sets justify that the rethinking framework indeed improves MLC performance across different evaluation criteria and leads to superior performance over state-of-the-art MLC algorithms.
Background and Objective: Code assignment is of paramount importance in many levels in modern hospitals, from ensuring accurate billing process to creating a valid record of patient care history. However, the coding process is tedious and subjective, and it requires medical coders with extensive training. This study aims to evaluate the performance of deep-learning-based systems to automatically map clinical notes to ICD-9 medical codes. Methods: The evaluations of this research are focused on end-to-end learning methods without manually defined rules. Traditional machine learning algorithms, as well as state-of-the-art deep learning methods such as Recurrent Neural Networks and Convolution Neural Networks, were applied to the Medical Information Mart for Intensive Care (MIMIC-III) dataset. An extensive number of experiments was applied to different settings of the tested algorithm. Results: Findings showed that the deep learning-based methods outperformed other conventional machine learning methods. From our assessment, the best models could predict the top 10 ICD-9 codes with 0.6957 F1 and 0.8967 accuracy and could estimate the top 10 ICD-9 categories with 0.7233 F1 and 0.8588 accuracy. Our implementation also outperformed existing work under certain evaluation metrics. Conclusion: A set of standard metrics was utilized in assessing the performance of ICD-9 code assignment on MIMIC-III dataset. All the developed evaluation tools and resources are available online, which can be used as a baseline for further research.
Machine learning has played an important role in information retrieval (IR) in recent times. In search engines, for example, query keywords are accepted and documents are returned in order of relevance to the given query; this can be cast as a multi-label ranking problem in machine learning. Generally, the number of candidate documents is extremely large (from several thousand to several million); thus, the classifier must handle many labels. This problem is referred to as extreme multi-label classification (XMLC). In this paper, we propose a novel approach to XMLC termed the Sparse Weighted Nearest-Neighbor Method. This technique can be derived as a fast implementation of state-of-the-art (SOTA) one-versus-rest linear classifiers for very sparse datasets. In addition, we show that the classifier can be written as a sparse generalization of a representer theorem with a linear kernel. Furthermore, our method can be viewed as the vector space model used in IR. Finally, we show that the Sparse Weighted Nearest-Neighbor Method can process data points in real time on XMLC datasets with equivalent performance to SOTA models, with a single thread and smaller storage footprint. In particular, our method exhibits superior performance to the SOTA models on a dataset with 3 million labels.
The goal in extreme multi-label classification is to learn a classifier which can assign a small subset of relevant labels to an instance from an extremely large set of target labels. Datasets in extreme classification exhibit a long tail of labels which have small number of positive training instances. In this work, we pose the learning task in extreme classification with large number of tail-labels as learning in the presence of adversarial perturbations. This view motivates a robust optimization framework and equivalence to a corresponding regularized objective. Under the proposed robustness framework, we demonstrate efficacy of Hamming loss for tail-label detection in extreme classification. The equivalent regularized objective, in combination with proximal gradient based optimization, performs better than state-of-the-art methods on propensity scored versions of precision@k and nDCG@k(upto 20% relative improvement over PFastreXML - a leading tree-based approach and 60% relative improvement over SLEEC - a leading label-embedding approach). Furthermore, we also highlight the sub-optimality of a sparse solver in a widely used package for large-scale linear classification, which is interesting in its own right. We also investigate the spectral properties of label graphs for providing novel insights towards understanding the conditions governing the performance of Hamming loss based one-vs-rest scheme vis-\`a-vis label embedding methods.
The task of Fine-grained Entity Type Classification (FETC) consists of assigning types from a hierarchy to entity mentions in text. Existing methods rely on distant supervision and are thus susceptible to noisy labels that can be out-of-context or overly-specific for the training sentence. Previous methods that attempt to address these issues do so with heuristics or with the help of hand-crafted features. Instead, we propose an end-to-end solution with a neural network model that uses a variant of cross- entropy loss function to handle out-of-context labels, and hierarchical loss normalization to cope with overly-specific ones. Also, previous work solve FETC a multi-label classification followed by ad-hoc post-processing. In contrast, our solution is more elegant: we use public word embeddings to train a single-label that jointly learns representations for entity mentions and their context. We show experimentally that our approach is robust against noise and consistently outperforms the state-of-the-art on established benchmarks for the task.
Multi-label classification is an important yet challenging task in natural language processing. It is more complex than single-label classification in that the labels tend to be correlated. Existing methods tend to ignore the correlations between labels. Besides, different parts of the text can contribute differently for predicting different labels, which is not considered by existing models. In this paper, we propose to view the multi-label classification task as a sequence generation problem, and apply a sequence generation model with a novel decoder structure to solve it. Extensive experimental results show that our proposed methods outperform previous work by a substantial margin. Further analysis of experimental results demonstrates that the proposed methods not only capture the correlations between labels, but also select the most informative words automatically when predicting different labels.